Book section · February 8, 2017
About 100,000 species of fungi have been described so far, of which a high percentage obtain nutrients by living in close association with other organisms, mainly plants. Many fungi are pathogenic and can have important impact on human health or lead to se ...
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Book section · January 1, 2016
Recombination, both crossover and gene conversion, plays fundamental roles in evolution by generating novel allele combinations, as well as by increasing the genetic diversity and facilitating natural selection. In many fungal species, recombination is als ...
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Book section · October 20, 2014
In this chapter, the author brings the various types of evidence for sexuality and asexuality in the microsporidia, ranging from observations of life cycles under the light and electron microscope to population genetic analyses of recombination and surveys ...
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Book section · January 1, 2014
This chapter outlines issues that were quickly explored, starting with the realization in 2001 that Vancouver Island was a hot spot for a pathogen not previously described as endemic and not restricted to tropical and subtropical climates. The picture of t ...
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Book section · January 1, 2014
The Cryptococcus mating-type locus (MAT) locus has emerged as an exemplary model to elucidate general principles governing the assembly and function of gene clusters. Moreover, comparative genomic studies of the evolutionary trajectory of MAT in the pathog ...
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Book section · January 1, 2014
This chapter reviews the discovery of both opposite-sex and unisexual reproduction and illustrates how these pathways are molecularly controlled and the central cell biology questions that remain to be addressed. Fungal sexual reproduction is genetically r ...
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Book section · January 1, 2014
G-protein-coupled receptors (GPCRs) are an important receptor gene family and play important roles in sensing sugars in eukaryotic organisms, including fungi. Recent studies on the interactions between Cryptococcus and plants, a major environmental niche, ...
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Book section · January 1, 2014
Cryptococcus neoformans and Cryptococcus gattii are closely related basidiomycetous fungi that commonly infect humans to predominantly cause meningoencephalitis. Both grow as budding yeasts in the environment and in the infected host yet undergo a dimorphi ...
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Book section · January 1, 2014
While many fungi have a characterized sexual cycle, the pathogenic fungi represent a special example in which sexuality is uncommon and sexual mechanisms are unusual or cryptic. Given their evolutionary relationship to model organisms such as Saccharomyces ...
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Book section · January 1, 2014
Sexual systems are classified into heterothallism or homothallism in fungi. This chapter focuses on examples of homothallic fungi and how their sexuality is governed. Conversions between heterothallic and homothallic sexual cycles are common evolutionary t ...
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Book section · January 1, 2014
The best-studied species to date are the human pathogens Candida albicans and C. glabrata. However, neither of these species is as yet known to possess a complete meiotic sexual cycle. C. lusitaniae, C. guilliermondii, and C. krusei are three members of th ...
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Book section · January 1, 2014
Of all the fungi, production of sexual structures is most prominent in the members of the phylum Basidiomycota. The sexual cycles of fungi have been well studied for several decades. Research has shown that although enormous variation exists between the se ...
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Book section · January 1, 2011
In 2007, the first confirmed case of Cryptococcus gattii was reported in the state of North Carolina, USA. An otherwise healthy human immunodeficiency virus (HIV) negative male patient presented with a large upper thigh cryptococcoma in February, which was ...
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Book section · January 1, 2011
We summarize current knowledge on the structure of mating type loci in different species of basidiomycetes, giving special consideration to bipolar and tetrapolar heterothallic species. In all three subphyla of the Basidiomycota, heterothallic bipolar, het ...
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https://orcid.org/0000-0001-6369-5995