Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral Fellow, Molecular Genetics, NIEHS 1994 - 1999
  • Ph.D., Pennsylvania State University 1994
  • B.S., North Carolina State University 1988
• 

  Duke Appointment History

  • Associate Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2014 - 2016
  • Associate Research Professor in the Institute for Genome Sciences & Policy, Institutes and Centers, School of Medicine 2006 - 2014
  • Assistant Research Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2002 - 2006
  • Assistant Research Professor of Genetics, School of Medicine, Duke University 2001 - 2002
• Research
• 

  Selected Grants

  • A comprehensive research resource to define mechanisms underlying microbial regulation of host metabolism in pediatric obesity and obesity-targeted therapeutics awarded by National Institutes of Health 2016 - 2021
  • A hands-on, integrative next-generation sequencing course: design, experiment, and analysis awarded by National Institutes of Health 2016 - 2019
  • 3D Biology Signatures defined by Nanostring Max System awarded by North Carolina Biotechnology Center 2018 - 2019
  • Biodosimetry High-Throughput Test awarded by DxTerity Diagnostics 2017 - 2018
  • Single cell analysis of intratumoral heterogeneity in parathyroid neoplasia awarded by National Institutes of Health 2015 - 2017
  • Point of Care Biodosimeter awarded by Department of Health and Human Services 2009 - 2016
  • Alternative splicing and epithelial-mesenchymal plasticity in prostate tumors awarded by National Institutes of Health 2008 - 2014
  • Validating Molecular Signature Risk Models of NSCLC awarded by National Institutes of Health 2006 - 2012
  • Intellectual Property Challenges for the Development of Genomic Diagnostics awarded by National Institutes of Health 2009 - 2012
  • Molecular mechanisms of altered calcium sensing in human parathyroid disease awarded by National Institutes of Health 2010 - 2012
  • Novel Zebrafish Models to Study Toxicity of PCBs and Pesticides During Pregnancy awarded by National Institutes of Health 2007 - 2011
  • Neurosciences Microarray Center awarded by National Institutes of Health 2005 - 2011
  • Refining and Validating Genomic Signatures in Lung Cancer awarded by National Institutes of Health 2009 - 2010
  • Prospective Validation of Genomic Signatures of Chemosensitivity in NSCLC awarded by National Institutes of Health 2009 - 2010
  • Multiscale Integrative Immunology for Adjuvant Develpmnt awarded by National Institutes of Health 2005 - 2010
  • Duke-NHLBI Functional Microarray Facility awarded by National Institutes of Health 2002 - 2006
  • Neurosciences Microarray Center awarded by National Institutes of Health 2002 - 2005
  • Duke/NIDDK Functional Genomics Center awarded by National Institutes of Health 2000 - 2003
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Iversen, ES, McCarthy, JM, Bell Burdett, K, Lipton, G, Phillips, G, Dressman, H, Ross, J, and Chao, N. "Bridging the gaps: using an NHP model to predict single dose radiation absorption in humans." International Journal of Radiation Biology (October 29, 2018): 1-10.  Full Text
    • Balenga, N, Azimzadeh, P, Hogue, JA, Staats, PN, Shi, Y, Koh, J, Dressman, H, and Olson, JA. "Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling." Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research 32, no. 3 (March 2017): 654-666.  Full Text
    • Himburg, HA, Sasine, J, Yan, X, Kan, J, Dressman, H, and Chute, JP. "A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation." Radiation Research 186, no. 2 (August 2016): 141-152.  Full Text
    • Siamakpour-Reihani, S, Owzar, K, Jiang, C, Scarbrough, PM, Craciunescu, OI, Horton, JK, Dressman, HK, Blackwell, KL, and Dewhirst, MW. "Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival." International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 31, no. 4 (June 2015): 386-395.  Full Text
    • Zheng, L, Yan, X, Suchindran, S, Dressman, H, Chute, JP, and Lucas, J. "Biological pathway selection through Bayesian integrative modeling." Statistical applications in genetics and molecular biology 13, no. 4 (August 2014): 435-457.  Full Text
    • Lucas, J, Dressman, HK, Suchindran, S, Nakamura, M, Chao, NJ, Himburg, H, Minor, K, Phillips, G, Ross, J, Abedi, M, Terbrueggen, R, and Chute, JP. "A translatable predictor of human radiation exposure." Plos One 9, no. 9 (January 2014): e107897-null.  Full Text  Open Access Copy
    • Zheng, L, Yan, X, Suchindran, S, Dressman, H, Chute, JP, and Lucas, J. "Biological pathway selection through Bayesian integrative modeling." Statistical Applications in Genetics and Molecular Biology 13, no. 6 (January 1, 2014).  Full Text
    • "An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer." Plos One 6, no. 9 (December 1, 2011).  Full Text
    • Freedman, JA, Augustine, CK, Selim, AM, Holshausen, KC, Wei, Z, Tsamis, KA, Hsu, DS, Dressman, HK, Barry, WT, Tyler, DS, and Nevins, JR. "A methodology for utilization of predictive genomic signatures in FFPE samples. (Published online)" BMC Med Genomics 4 (July 11, 2011): 58-.  Full Text  Link to Item
    • Koh, J, Dar, M, Untch, BR, Dixit, D, Shi, Y, Yang, Z, Adam, MA, Dressman, H, Wang, X, Gesty-Palmer, D, Marks, JR, Spurney, R, Druey, KM, and Olson, JA. "Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor." Mol Endocrinol 25, no. 5 (May 2011): 867-876.  Full Text  Link to Item
    • Meadows, SK, Dressman, HK, Daher, P, Himburg, H, Russell, JL, Doan, P, Chao, NJ, Lucas, J, Nevins, JR, and Chute, JP. "Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. (Published online)" PLoS One 5, no. 7 (July 12, 2010): e11535-.  Full Text  Open Access Copy  Link to Item
    • Barry, W, Acharya, C, Datto, MB, Dressman, HK, Marcom, PK, Ready, N, Ginsburg, GS, Potti, A, and Nevins, JR. "Utilization of genomic signatures for chemotherapy response in prospective clinical studies." Journal of Clinical Oncology 28, no. 15_suppl (May 20, 2010): 10513-10513.  Full Text
    • Barry, WT, Kernagis, DN, Dressman, HK, Griffis, RJ, Hunter, JD, Olson, JA, Marks, JR, Ginsburg, GS, Marcom, PK, Nevins, JR, Geradts, J, and Datto, MB. "Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome." Journal of Clinical Oncology 28, no. 13 (May 2010): 2198-2206.  Full Text
    • Barnett, JC, Bean, SM, Whitaker, RS, Kondoh, E, Baba, T, Fujii, S, Marks, JR, Dressman, HK, Murphy, SK, and Berchuck, A. "Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype." Gynecologic Oncology 116, no. 3 (March 2010): 556-562.  Full Text
    • Tebbit, CL, Zhai, J, Untch, BR, Ellis, MJ, Dressman, HK, Bentley, RC, Baker, JA, Marcom, PK, Nevins, JR, Marks, JR, and Olson, JA. "Novel tumor sampling strategies to enable microarray gene expression signatures in breast cancer: a study to determine feasibility and reproducibility in the context of clinical care." Breast Cancer Research and Treatment 118, no. 3 (December 2009): 635-643.  Full Text
    • Boren, T, Xiong, Y, Hakam, A, Wenham, R, Apte, S, Chan, G, Kamath, SG, Chen, D-T, Dressman, H, and Lancaster, JM. "MicroRNAs and their target messenger RNAs associated with ovarian cancer response to chemotherapy." Gynecologic Oncology 113, no. 2 (May 2009): 249-255.  Full Text
    • Berchuck, A, Iversen, ES, Luo, J, Clarke, JP, Horne, H, Levine, DA, Boyd, J, Alonso, MA, Secord, AA, Bernardini, MQ, Barnett, JC, Boren, T, Murphy, SK, Dressman, HK, Marks, JR, and Lancaster, JM. "Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 15, no. 7 (April 2009): 2448-2455.  Full Text
    • Hsu, DS, Acharya, CR, Balakumaran, BS, Riedel, RF, Kim, MK, Stevenson, M, Tuchman, S, Mukherjee, S, Barry, W, Dressman, HK, Nevins, JR, Powers, S, Mu, D, and Potti, A. "Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer." Proc Natl Acad Sci U S A 106, no. 13 (March 31, 2009): 5312-5317.  Full Text  Link to Item
    • Pilon, AM, Arcasoy, MO, Dressman, HK, Vayda, SE, Maksimova, YD, Sangerman, JI, Gallagher, PG, and Bodine, DM. "Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2." Molecular and Cellular Biology 28, no. 24 (December 2008): 7394-7401.  Full Text
    • Haskins, KA, Russell, JF, Gaddis, N, Dressman, HK, and Aballay, A. "Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity." Developmental Cell 15, no. 1 (July 2008): 87-97.  Full Text
    • Cragun, JM, Boren, T, Xiong, Y, Indermaur, M, Kamath, S, Cottrill, H, Balducci, L, Sayer, R, Dressman, HK, Berchuck, A, and Lancaster, J. "Gene expression determinants of ovarian cancer platinum-response in older women." J Clin Oncol 26, no. 15_suppl (May 20, 2008): 22059-.  Link to Item
    • Cragun, JM, Boren, T, Xiong, Y, Indermaur, M, Kamath, S, Cottrill, H, Balducci, L, Sayer, R, Dressman, HK, Berchuck, A, and Lancaster, J. "Gene expression determinants of ovarian cancer platinum-response in older women." JOURNAL OF CLINICAL ONCOLOGY 26, no. 15 (May 20, 2008).  Full Text  Link to Item
    • Hsu, SD, Acharya, CR, Riedel, RF, Redman, RC, Garman, KS, Dressman, HK, Ginsburg, G, Powers, S, Mu, D, and Potti, A. "Use of co-activation of lung cancer specific developmental pathway genes, TTF-1, NKX2-8, and PAX9, to predict prognosis and guide therapeutic strategies." JOURNAL OF CLINICAL ONCOLOGY 26, no. 15 (May 20, 2008).  Full Text  Link to Item
    • Acharya, CR, Hsu, DS, Anders, CK, Anguiano, A, Salter, KH, Walters, KS, Redman, RC, Tuchman, SA, Moylan, CA, Mukherjee, S, Barry, WT, Dressman, HK, Ginsburg, GS, Marcom, KP, Garman, KS, Lyman, GH, Nevins, JR, and Potti, A. "Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer." JAMA 299, no. 13 (April 2, 2008): 1574-1587.  Full Text  Link to Item
    • Meadows, SK, Dressman, HK, Muramoto, GG, Himburg, H, Salter, A, Wei, Z, Ginsburg, GS, Chao, NJ, Nevins, JR, and Chute, JP. "Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. (Published online)" PLoS One 3, no. 4 (April 2, 2008): e1912-.  Full Text  Open Access Copy  Link to Item
    • Boren, T, Dressman, HK, Kamath, S, Wei, ZZ, Cragun, J, Humphrey, M, Chen, N, Xiong, Y, and Lancaster, JM. "MicroRNAs and their target messenger RNAs associated with the development of endometrial carcinoma." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S88-S89.  Link to Item
    • Boren, T, Dressman, HK, Wei, ZZ, Martino, MA, Zhang, T, Palmer, J, and Lancaster, JM. "Gene expression patterns in formalin-fixed, paraffin-embedded endometrial tissue associated with lymph node metastasis." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S89-S90.  Link to Item
    • Indermaur, MD, Boren, T, Cragun, J, Wenham, R, Aptel, S, Chan, G, Karnath, SG, Wei, Z, Dressman, HK, and Lancaster, JM. "Formalin-fixed, paraffin-embedded ovarian cancer gene expression signatures associated with platinum response." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S39-S39.  Link to Item
    • Indermaur, MD, Boren, T, Kamath, SG, Wei, Z, Wenham, R, Apte, S, Dressman, HK, and Lancaster, JM. "Targeted therapy to improve endometrial cancer response to doxorubicin." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S82-S82.  Link to Item
    • Boren, T, Xiong, Y, Hakam, A, Wenham, R, Apte, S, Wei, Z, Kamath, S, Chen, D-T, Dressman, H, and al, E. "MicroRNAs and their target messenger RNAs associated with endometrial carcinogenesis." Gynecologic Oncology 110, no. 2 (2008): 206-215.  Full Text
    • Salter, KH, Acharya, CR, Walters, KS, Redman, R, Anguiano, A, Garman, KS, Anders, CK, Mukherjee, S, Dressman, HK, Barry, WT, Marcom, KP, Olson, J, Nevins, JR, and Potti, A. "An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer." Plos One 3, no. 4 (January 2008): e1908-null.  Full Text  Open Access Copy
    • Hsu, DS, Balakumaran, BS, Acharya, CR, Vlahovic, V, Walters, KS, Garman, K, Anders, C, Riedel, RF, Lancaster, J, Harpole, D, Dressman, HK, Nevins, JR, Febbo, PG, and Potti, A. "Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer." J Clin Oncol 25, no. 28 (October 1, 2007): 4350-4357.  Full Text  Link to Item
    • Dressman, HK, Muramoto, GG, Chao, NJ, Meadows, S, Marshall, D, Ginsburg, GS, Nevins, JR, and Chute, JP. "Gene expression signatures that predict radiation exposure in mice and humans." Plos Medicine 4, no. 4 (April 2007): e106-null.  Full Text  Open Access Copy
    • Learn, CA, Grossi, PM, Schmittling, RJ, Xie, W, Mitchell, DA, Karikari, I, Wei, Z, Dressman, H, and Sampson, JH. "Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity." J Neuroimmunol 182, no. 1-2 (January 2007): 63-72.  Full Text  Link to Item
    • Learn, CA, Fecci, PE, Schmittling, RJ, Xie, W, Karikari, I, Mitchell, DA, Archer, GE, Wei, Z, Dressman, H, and Sampson, JH. "Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 12, no. 24 (December 2006): 7306-7315.  Full Text
    • Cheng, SH, Horng, C-F, West, M, Huang, E, Pittman, J, Tsou, M-H, Dressman, H, Chen, C-M, Tsai, SY, Jian, JJ, Liu, M-C, Nevins, JR, and Huang, AT. "Genomic prediction of locoregional recurrence after mastectomy in breast cancer." J Clin Oncol 24, no. 28 (October 1, 2006): 4594-4602.  Full Text  Link to Item
    • Lancaster, JM, Dressman, HK, Clarke, JP, Sayer, RA, Martino, MA, Cragun, JM, Henriott, AH, Gray, J, Sutphen, R, Elahi, A, Whitaker, RS, West, M, Marks, JR, Nevins, JR, and Berchuck, A. "Identification of genes associated with ovarian cancer metastasis using microarray expression analysis." Int J Gynecol Cancer 16, no. 5 (September 2006): 1733-1745.  Full Text  Link to Item
    • Gollob, JA, Sciambi, CJ, Peterson, BL, Richmond, T, Thoreson, M, Moran, K, Dressman, HK, Jelinek, J, and Issa, J-PJ. "Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 12, no. 15 (August 2006): 4619-4627.  Full Text
    • Dressman, HK, Bild, A, Garst, J, Harpole, D, and Potti, A. "Genomic signatures in non-small-cell lung cancer: targeting the targeted therapies." Curr Oncol Rep 8, no. 4 (July 2006): 252-257. (Review)  Link to Item
    • Chute, JP, Muramoto, GG, Dressman, HK, Wolfe, G, Chao, NJ, and Lin, S. "Molecular profile and partial functional analysis of novel endothelial cell-derived growth factors that regulate hematopoiesis." Stem Cells 24, no. 5 (May 2006): 1315-1327.  Full Text  Link to Item
    • Lux, A, Salway, F, Dressman, HK, Kröner-Lux, G, Hafner, M, Day, PJR, Marchuk, DA, and Garland, J. "ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression. (Published online)" BMC Cardiovasc Disord 6 (April 4, 2006): 13-.  Full Text  Link to Item
    • Damodaran, TV, Greenfield, ST, Patel, AG, Dressman, HK, Lin, SK, and Abou-Donia, MB. "Toxicogenomic studies of the rat brain at an early time point following acute sarin exposure." Neurochemical Research 31, no. 3 (March 2006): 367-381.  Full Text
    • Potti, A, Bild, A, Dressman, HK, Lewis, DA, Nevins, JR, and Ortel, TL. "Gene-expression patterns predict phenotypes of immune-mediated thrombosis." Blood 107, no. 4 (February 15, 2006): 1391-1396.  Full Text  Link to Item
    • Damodaran, TV, Patel, AG, Greenfield, ST, Dressman, HK, Lin, SM, and Abou-Donia, MB. "Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure." Biochemical Pharmacology 71, no. 4 (February 2006): 497-520.  Full Text
    • Dressman, HK, Hans, C, Bild, A, Olson, JA, Rosen, E, Marcom, PK, Liotcheva, VB, Jones, EL, Vujaskovic, Z, Marks, J, Dewhirst, MW, West, M, Nevins, JR, and Blackwell, K. "Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 12, no. 3 Pt 1 (February 2006): 819-826.  Full Text
    • Bild, AH, Yao, G, Chang, JT, Wang, Q, Potti, A, Chasse, D, Joshi, M-B, Harpole, D, Lancaster, JM, Berchuck, A, Olson, JA, Marks, JR, Dressman, HK, West, M, and Nevins, JR. "Oncogenic pathway signatures in human cancers as a guide to targeted therapies." Nature 439, no. 7074 (January 2006): 353-357.  Full Text
    • Dressman, HK, Barley-Maloney, L, Rowlette, L-L, Agris, PF, and Garcia-Blanco, MA. "Assessing incomplete deprotection of microarray oligonucleotides in situ." Nucleic Acids Res 34, no. 19 (2006): e131-.  Full Text  Link to Item
    • Boutlis, CS, Dressman, HK, Tjitra, E, Maniboey, H, Nevins, JR, Weinberg, JB, and Anstey, NM. "Patterns of gene expression that characterize outcomes of Plasmodium falciparum infection." AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 73, no. 6 (December 2005): 225-225.  Link to Item
    • Black, EP, Hallstrom, T, Dressman, HK, West, M, and Nevins, JR. "Distinctions in the specificity of E2F function revealed by gene expression signatures." Proceedings of the National Academy of Sciences of the United States of America 102, no. 44 (November 2005): 15948-15953.  Full Text
    • Gollob, JA, Sciambi, CJ, Huang, Z, and Dressman, HK. "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." Cancer Res 65, no. 19 (October 1, 2005): 8869-8877.  Full Text  Link to Item
    • Gollob, JA, Sciambi, CJ, Huang, Z, and Dressman, HK. "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." Cancer Research 65, no. 19 (October 2005): 8869-8877.  Full Text
    • Delong, M, Yao, G, Wang, Q, Dobra, A, Black, EP, Chang, JT, Bild, A, West, M, Nevins, JR, and Dressman, H. "DIG--a system for gene annotation and functional discovery." Bioinformatics (Oxford, England) 21, no. 13 (July 2005): 2957-2959.  Full Text
    • Martino, MA, Elahi, A, Sutphen, R, Klippel, C, Boren, T, Dressman, HK, Berchuck, A, and Lancaster, JM. "Expression analysis of genes involved in ovarian cancer metastasis." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 23, no. 16_suppl (June 2005): 5038-.
    • Berchuck, A, Iversen, ES, Lancaster, JM, Pittman, J, Luo, J, Lee, P, Murphy, S, Dressman, HK, Febbo, PG, West, M, Nevins, JR, and Marks, JR. "Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers." Clin Cancer Res 11, no. 10 (May 15, 2005): 3686-3696.  Full Text  Link to Item
    • Bammler, T, Beyer, RP, Bhattacharya, S, Boorman, GA, Boyles, A, Bradford, BU, Bumgarner, RE, Bushel, PR, Chaturvedi, K, Choi, D, Cunningham, ML, Deng, S, Dressman, HK, Fannin, RD, Farin, FM, Freedman, JH, Fry, RC, Harper, A, Humble, MC, Hurban, P, Kavanagh, TJ, Kaufmann, WK, Kerr, KF, Jing, L, Lapidus, JA, Lasarev, MR, Li, J, Li, Y-J, Lobenhofer, EK, Lu, X, Malek, RL, Milton, S, Nagalla, SR, O'malley, JP, Palmer, VS, Pattee, P, Paules, RS, Perou, CM, Phillips, K, Qin, L-X, Qiu, Y, Quigley, SD, Rodland, M, Rusyn, I, Samson, LD, Schwartz, DA, Shi, Y, Shin, J-L, Sieber, SO, Slifer, S, Speer, MC, Spencer, PS, Sproles, DI, Swenberg, JA, Suk, WA, Sullivan, RC, Tian, R, Tennant, RW, Todd, SA, Tucker, CJ, Van Houten, B, Weis, BK, Xuan, S, Zarbl, H, and Members of the Toxicogenomics Research Consortium, . "Standardizing global gene expression analysis between laboratories and across platforms." Nature Methods 2, no. 5 (May 2005): 351-356.  Full Text
    • Deng, S, Dressman, HK, Fannin, RD, Farin, FM, Freedman, JH, Fry, RC, Harper, A, Humble, MC, Hurban, P, Kavanagh, TJ, Kaufmann, WK, Kerr, KF, Jing, L, Lapidus, JA, Lasarev, MR, Li, J, Li, YJ, Lobenhofer, EK, Lu, X, Malek, RL, Milton, S, Nagalla, SR, O'Malley, JP, Palmer, VS, Pattee, P, Paules, RS, Perou, CM, Phillips, K, Qin, LX, Qiu, Y, Quigley, SD, Rodland, M, Rusyn, I, Samson, LD, Schwartz, DA, Shi, Y, Shin, JL, Sieber, SO, Slifer, S, Speer, MC, Spencer, PS, Sproles, DI, Swenberg, JA, Suk, WA, Sullivan, RC, Tian, R, Tennant, RW, Todd, SA, Tucker, CJ, Van Houten, B, Weis, BK, Xuan, S, and Zarbl, H. "Standardizing global gene expression analysis between laboratories and across platforms." Nature Methods 2, no. 5 (May 1, 2005): 1-6.  Full Text
    • Rich, JN, Hans, C, Jones, B, Iversen, ES, McLendon, RE, Rasheed, BKA, Dobra, A, Dressman, HK, Bigner, DD, Nevins, JR, and West, M. "Gene expression profiling and genetic markers in glioblastoma survival." Cancer Research 65, no. 10 (May 2005): 4051-4058.  Full Text
    • Seo, D, Wang, T, Dressman, H, Herderick, EE, Iversen, ES, Dong, C, Vata, K, Milano, CA, Rigat, F, Pittman, J, Nevins, JR, West, M, and Goldschmidt-Clermont, PJ. "Gene expression phenotypes of atherosclerosis." Arterioscler Thromb Vasc Biol 24, no. 10 (October 2004): 1922-1927.  Full Text  Link to Item
    • Pittman, J, Huang, E, Dressman, H, Horng, C-F, Cheng, SH, Tsou, M-H, Chen, C-M, Bild, A, Iversen, ES, Huang, AT, Nevins, JR, and West, M. "Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes." Proceedings of the National Academy of Sciences of the United States of America 101, no. 22 (June 2004): 8431-8436.  Full Text
    • Berchuck, A, Iversen, ES, Lancaster, JM, Dressman, HK, West, M, Nevins, JR, and Marks, JR. "Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays." Am J Obstet Gynecol 190, no. 4 (April 2004): 910-925.  Full Text  Link to Item
    • Advani, AS, Dressman, HK, Quiroz, M, Taylor, GA, and Pendergast, AM. "Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis." Leukemia Research 28, no. 3 (March 2004): 285-294.  Full Text
    • Hashimoto, T, Lawton, MT, Wen, G, Yang, G-Y, Chaly, T, Stewart, CL, Dressman, HK, Barbaro, NM, Marchuk, DA, and Young, WL. "Gene microarray analysis of human brain arteriovenous malformations." Neurosurgery 54, no. 2 (February 2004): 410-423.  Full Text
    • Lancaster, JM, Dressman, HK, Whitaker, RS, Havrilesky, L, Gray, J, Marks, JR, Nevins, JR, and Berchuck, A. "Gene expression patterns that characterize advanced stage serous ovarian cancers." J Soc Gynecol Investig 11, no. 1 (January 2004): 51-59.  Link to Item
    • Qin, L-X, Kerr, KF, and Contributing Members of the Toxicogenomics Research Consortium, . "Empirical evaluation of data transformations and ranking statistics for microarray analysis." Nucleic Acids Research 32, no. 18 (January 2004): 5471-5479.  Full Text
    • Nevins, JR, Huang, ES, Dressman, H, Pittman, J, Huang, AT, and West, M. "Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction." Human Molecular Genetics 12 Spec No 2 (October 2003): R153-R157. (Review)  Full Text
    • Ellis, MJ, Rosen, E, Dressman, H, and Marks, J. "Neoadjuvant comparisons of aromatase inhibitors and tamoxifen: pretreatment determinants of response and on-treatment effect." The Journal of Steroid Biochemistry and Molecular Biology 86, no. 3-5 (September 2003): 301-307. (Review)  Full Text
    • Huang, ES, Black, EP, Dressman, H, West, M, and Nevins, JR. "Gene expression phenotypes of oncogenic signaling pathways." Cell Cycle (Georgetown, Tex.) 2, no. 5 (September 2003): 415-417. (Review)
    • Huang, E, Ishida, S, Pittmann, J, Dressman, H, Bild, A, Kloos, M, D'Amico, M, Pestell, RG, West, M, and Nevins, JR. "Erratum: Gene expression phenotypic models that predict the activity of oncogenic pathways." Nature Genetics 34, no. 4 (August 2003): 465-465.  Full Text
    • Black, EP, Huang, E, Dressman, H, Rempel, R, Laakso, N, Asa, SL, Ishida, S, West, M, and Nevins, JR. "Distinct gene expression phenotypes of cells lacking Rb and Rb family members." Cancer Res 63, no. 13 (July 1, 2003): 3716-3723.  Link to Item
    • Huang, E, Ishida, S, Pittman, J, Dressman, H, Bild, A, Kloos, M, D'Amico, M, Pestell, RG, West, M, and Nevins, JR. "Gene expression phenotypic models that predict the activity of oncogenic pathways." Nature Genetics 34, no. 2 (June 2003): 226-230.  Full Text
    • Huang, E, Cheng, SH, Dressman, H, Pittman, J, Tsou, MH, Horng, CF, Bild, A, Iversen, ES, Liao, M, Chen, CM, West, M, Nevins, JR, and Huang, AT. "Gene expression predictors of breast cancer outcomes." Lancet 361, no. 9369 (May 10, 2003): 1590-1596.  Full Text  Link to Item
    • Bebenek, A, Carver, GT, Dressman, HK, Kadyrov, FA, Haseman, JK, Petrov, V, Konigsberg, WH, Karam, JD, and Drake, JW. "Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins." Genetics 162, no. 3 (November 2002): 1003-1018.  Link to Item
    • West, M, Blanchette, C, Dressman, H, Huang, E, Ishida, S, Spang, R, Zuzan, H, Olson, JA, Marks, JR, and Nevins, JR. "Predicting the clinical status of human breast cancer by using gene expression profiles." Proceedings of the National Academy of Sciences of the United States of America 98, no. 20 (September 18, 2001): 11462-11467.  Full Text
    • Bebenek, A, Dressman, HK, Carver, GT, Ng, S, Petrov, V, Yang, G, Konigsberg, WH, Karam, JD, and Drake, JW. "Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69." J Biol Chem 276, no. 13 (March 30, 2001): 10387-10397.  Full Text  Link to Item
    • Dressman, HK, and Drake, JW. "Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene." Journal of Bacteriology 181, no. 14 (July 1999): 4391-4396.
    • Paddison, P, Abedon, ST, Dressman, HK, Gailbreath, K, Tracy, J, Mosser, E, Neitzel, J, Guttman, B, and Kutter, E. "The roles of the bacteriophage T4 r genes in lysis inhibition and fine-structure genetics: a new perspective." Genetics 148, no. 4 (April 1998): 1539-1550.
    • Dressman, HK, Wang, CC, Karam, JD, and Drake, JW. "Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment." Proceedings of the National Academy of Sciences of the United States of America 94, no. 15 (July 1997): 8042-8046.  Full Text
    • Humphries, JE, Dressman, HK, and Williams, ME. "Immunoglobulin gene rearrangement in multiple myeloma: limitations of Southern blot analysis." Human Pathology 22, no. 10 (October 1991): 966-971.  Full Text

  • Other Articles

    • Hsu, DS, Balakumaran, BS, Acharya, CR, Vlahovic, V, Walters, KS, Garman, K, Anders, C, Riedel, RF, Lancaster, J, Harpole, D, and al, E. "Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer (Journal of Clinical Oncology (2007) 25, (4350-4357))." Journal of Clinical Oncology 28, no. 35 (2010): 5229--.  Full Text
    • Not Available, NA. "Prediction of optimal versus suboptimal cytoreduction of advanced-stage serious ovarian cancer with the use of microarrays." The Women'S Oncology Review 4, no. 3 (September 1, 2004): 203-204.  Full Text

  • Conference Papers

    • Danko, ME, Untch, BR, Tebbit, CL, Zhai, J, Dressman, HK, Bentley, RC, Baker, J, Marks, JR, Nevins, JR, and Jr, OJA. "A clinicogenomic model to predict lymph node metastasis in breast cancer." September 2008.  Full Text  Link to Item
    • Gallagher, PG, Pilon, AM, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, and Bodine, DM. "Failure of definitive erythropoiesis in EKLF-deficient mice." : Elsevier BV, March 2007.  Full Text
    • Pilon, AM, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, Bodine, DM, and Gallagher, PG. "EKLF-deficiency leads to multiple defects in erythropoiesis: Dysregulation of AHSP and E2F." : Elsevier BV, March 2007.  Full Text
    • Pilon, AM, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, Bodine, DM, and Gallagher, PG. "Defects in E2F1/2 expression are associated with abnormalities in cell cycle and differentiation in EKLF-deficient erythroid cells." November 16, 2006.  Link to Item
    • Gallagher, PG, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, and Bodine, DM. "A differentiation block in erythroid cells lacking erythroid krupple-like factor (EKLF)." November 16, 2005.  Link to Item
    • Potti, A, Dressman, HK, and Arcasoy, MO. "Gene expression patterns identify novel biologically relevant signaling and transcriptional pathways involved in terminal erythroid differentiation and polycythemia vera." November 16, 2005.  Link to Item
    • Bild, AH, Yao, G, Chang, JT, Wang, QL, Potti, A, Harpole, D, Lancaster, J, Berchuck, A, Olson, JA, Marks, J, Dressman, HK, West, M, and Nevins, JR. "Oncogenic pathway signatures in human cancers as a guide to targeted therapies." November 2005.  Link to Item
    • Martino, MA, Elahi, A, Sutphen, R, Klippel, C, Boren, T, Dressman, HK, Berchuck, A, and Lancaster, JM. "Expression analysis of genes involved in ovarian cancer metastasis." June 1, 2005.  Link to Item
    • Burch, LH, Yang, IV, Dressman, HK, Schwartz, DA, Guo, H, Kuo, PC, Cohen, HJ, and Lagoo-Deenadayalan, SA. "Transcriptional response to endotoxin in young adult and aged rats." Annual Meeting of the American-Geriatrics-Society. Orlando, FL. May 11, 2005 - May 15, 2005.: WILEY-BLACKWELL, April 1, 2005.  Link to Item
    • Pittman, JL, Tebbit, CL, Black, EP, Dressman, HK, Huang, ES, Olson, JA, Marks, JR, Marcom, PK, Huang, AT, West, M, and Nevins, JR. "Predictive models that combine multiple forms of genomic and clinical data to achieve personalized prediction of outcomes in breast cancer." 2004.  Link to Item
    • Advani, AS, Dressman, HK, Quiroz, M, Taylor, GA, and Pendergast, AM. "Elevated expression of numerous interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis." 44th Annual Meeting of the American-Society-of-Hematology. PHILADELPHIA, PENNSYLVANIA. December 6, 2002 - December 10, 2002.: AMER SOC HEMATOLOGY, November 16, 2002.  Link to Item

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