Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral Fellow, Molecular Genetics, NIEHS 1994 - 1999
  • Ph.D., Pennsylvania State University 1994
  • B.S., North Carolina State University 1988
• 

  Duke Appointment History

  • Associate Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2014 - 2016
  • Associate Research Professor in the Institute for Genome Sciences & Policy, Institutes and Centers, School of Medicine 2006 - 2014
  • Assistant Research Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2002 - 2006
  • Assistant Research Professor of Genetics, School of Medicine, Duke University 2001 - 2002
• Research
• 

  Selected Grants

  • A comprehensive research resource to define mechanisms underlying microbial regulation of host metabolism in pediatric obesity and obesity-targeted therapeutics awarded by National Institutes of Health 2016 - 2021
  • A hands-on, integrative next-generation sequencing course: design, experiment, and analysis awarded by National Institutes of Health 2016 - 2019
  • 3D Biology Signatures defined by Nanostring Max System awarded by North Carolina Biotechnology Center 2018 - 2019
  • Biodosimetry High-Throughput Test awarded by DxTerity Diagnostics 2017 - 2018
  • Single cell analysis of intratumoral heterogeneity in parathyroid neoplasia awarded by National Institutes of Health 2015 - 2017
  • Point of Care Biodosimeter awarded by Department of Health and Human Services 2009 - 2016
  • Alternative splicing and epithelial-mesenchymal plasticity in prostate tumors awarded by National Institutes of Health 2008 - 2014
  • Validating Molecular Signature Risk Models of NSCLC awarded by National Institutes of Health 2006 - 2012
  • Intellectual Property Challenges for the Development of Genomic Diagnostics awarded by National Institutes of Health 2009 - 2012
  • Molecular mechanisms of altered calcium sensing in human parathyroid disease awarded by National Institutes of Health 2010 - 2012
  • Novel Zebrafish Models to Study Toxicity of PCBs and Pesticides During Pregnancy awarded by National Institutes of Health 2007 - 2011
  • Neurosciences Microarray Center awarded by National Institutes of Health 2005 - 2011
  • Refining and Validating Genomic Signatures in Lung Cancer awarded by National Institutes of Health 2009 - 2010
  • Prospective Validation of Genomic Signatures of Chemosensitivity in NSCLC awarded by National Institutes of Health 2009 - 2010
  • Multiscale Integrative Immunology for Adjuvant Develpmnt awarded by National Institutes of Health 2005 - 2010
  • Duke-NHLBI Functional Microarray Facility awarded by National Institutes of Health 2002 - 2006
  • Neurosciences Microarray Center awarded by National Institutes of Health 2002 - 2005
  • Duke/NIDDK Functional Genomics Center awarded by National Institutes of Health 2000 - 2003
• Publications & Artistic Works
• 

  Selected Publications

  • Conference Papers

    • Danko, ME, Untch, BR, Tebbit, CL, Zhai, J, Dressman, HK, Bentley, RC, Baker, J, Marks, JR, Nevins, JR, and Jr, OJA. "A clinicogenomic model to predict lymph node metastasis in breast cancer." September 2008.  Full Text  Link to Item
    • Gallagher, PG, Pilon, AM, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, and Bodine, DM. "Failure of definitive erythropoiesis in EKLF-deficient mice." 2007.  Full Text  Link to Item
    • Pilon, AM, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, Bodine, DM, and Gallagher, PG. "EKLF-deficiency leads to multiple defects in erythropoiesis: Dysregulation of AHSP and E2F." 2007.  Full Text  Link to Item
    • Pilon, AM, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, Bodine, DM, and Gallagher, PG. "Defects in E2F1/2 expression are associated with abnormalities in cell cycle and differentiation in EKLF-deficient erythroid cells." November 16, 2006.  Link to Item
    • Gallagher, PG, Arcasoy, MO, Vayda, SE, Dressman, HK, Bieker, JJ, and Bodine, DM. "A differentiation block in erythroid cells lacking erythroid krupple-like factor (EKLF)." November 16, 2005.  Link to Item
    • Potti, A, Dressman, HK, and Arcasoy, MO. "Gene expression patterns identify novel biologically relevant signaling and transcriptional pathways involved in terminal erythroid differentiation and polycythemia vera." November 16, 2005.  Link to Item
    • Bild, AH, Yao, G, Chang, JT, Wang, QL, Potti, A, Harpole, D, Lancaster, J, Berchuck, A, Olson, JA, Marks, J, Dressman, HK, West, M, and Nevins, JR. "Oncogenic pathway signatures in human cancers as a guide to targeted therapies." November 2005.  Link to Item
    • Martino, MA, Elahi, A, Sutphen, R, Klippel, C, Boren, T, Dressman, HK, Berchuck, A, and Lancaster, JM. "Expression analysis of genes involved in ovarian cancer metastasis." June 1, 2005.  Link to Item
    • Burch, LH, Yang, IV, Dressman, HK, Schwartz, DA, Guo, H, Kuo, PC, Cohen, HJ, and Lagoo-Deenadayalan, SA. "Transcriptional response to endotoxin in young adult and aged rats." April 2005.  Link to Item
    • Pittman, JL, Tebbit, CL, Black, EP, Dressman, HK, Huang, ES, Olson, JA, Marks, JR, Marcom, PK, Huang, AT, West, M, and Nevins, JR. "Predictive models that combine multiple forms of genomic and clinical data to achieve personalized prediction of outcomes in breast cancer." 2004.  Link to Item
    • Advani, AS, Dressman, HK, Quiroz, M, Taylor, GA, and Pendergast, AM. "Elevated expression of numerous interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis." November 16, 2002.  Link to Item

  • Journal Articles

    • Balenga, N, Azimzadeh, P, Hogue, JA, Staats, PN, Shi, Y, Koh, J, Dressman, H, and Olson, JA. "Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 32, no. 3 (March 2017): 654-666.  Full Text
    • Himburg, HA, Sasine, J, Yan, X, Kan, J, Dressman, H, and Chute, JP. "A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation." Radiation research 186, no. 2 (August 2016): 141-152.  Full Text
    • Siamakpour-Reihani, S, Owzar, K, Jiang, C, Scarbrough, PM, Craciunescu, OI, Horton, JK, Dressman, HK, Blackwell, KL, and Dewhirst, MW. "Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival." International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 31, no. 4 (June 2015): 386-395.  Full Text
    • Zheng, L, Yan, X, Suchindran, S, Dressman, H, Chute, JP, and Lucas, J. "Biological pathway selection through Bayesian integrative modeling." Statistical applications in genetics and molecular biology 13, no. 4 (August 2014): 435-457.  Full Text
    • Lucas, J, Dressman, HK, Suchindran, S, Nakamura, M, Chao, NJ, Himburg, H, Minor, K, Phillips, G, Ross, J, Abedi, M, Terbrueggen, R, and Chute, JP. "A translatable predictor of human radiation exposure." PLoS ONE 9, no. 9 (January 2014): e107897-.  Full Text  Open Access Copy
    • Zheng, L, Yan, X, Suchindran, S, Dressman, H, Chute, JP, and Lucas, J. "Biological pathway selection through Bayesian integrative modeling." Statistical Applications in Genetics and Molecular Biology 13, no. 6 (January 1, 2014).  Full Text
    • Freedman, JA, Augustine, CK, Selim, AM, Holshausen, KC, Wei, Z, Tsamis, KA, Hsu, DS, Dressman, HK, Barry, WT, Tyler, DS, and Nevins, JR. "A methodology for utilization of predictive genomic signatures in FFPE samples. (Published online)" BMC Med Genomics 4 (July 11, 2011): 58-.  Full Text  Link to Item
    • Koh, J, Dar, M, Untch, BR, Dixit, D, Shi, Y, Yang, Z, Adam, MA, Dressman, H, Wang, X, Gesty-Palmer, D, Marks, JR, Spurney, R, Druey, KM, and Olson, JA. "Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor." Mol Endocrinol 25, no. 5 (May 2011): 867-876.  Full Text  Link to Item
    • Salter, KH, Acharya, CR, Walters, KS, Redman, R, Anguiano, A, Garman, KS, Anders, CK, Mukherjee, S, Dressman, HK, Barry, WT, Marcom, KP, Olson, J, Nevins, JR, and Potti, A. "An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer." PLoS ONE 6, no. 9 (2011).  Full Text
    • Meadows, SK, Dressman, HK, Daher, P, Himburg, H, Russell, JL, Doan, P, Chao, NJ, Lucas, J, Nevins, JR, and Chute, JP. "Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. (Published online)" PLoS One 5, no. 7 (July 12, 2010): e11535-.  Full Text  Open Access Copy  Link to Item
    • Barry, W, Acharya, C, Datto, MB, Dressman, HK, Marcom, PK, Ready, N, Ginsburg, GS, Potti, A, and Nevins, JR. "Utilization of genomic signatures for chemotherapy response in prospective clinical studies." Journal of Clinical Oncology 28, no. 15_suppl (May 20, 2010): 10513-10513.  Full Text
    • Barry, WT, Kernagis, DN, Dressman, HK, Griffis, RJ, Hunter, JD, Olson, JA, Marks, JR, Ginsburg, GS, Marcom, PK, Nevins, JR, Geradts, J, and Datto, MB. "Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome." J Clin Oncol 28, no. 13 (May 1, 2010): 2198-2206.  Full Text  Link to Item
    • Barnett, JC, Bean, SM, Whitaker, RS, Kondoh, E, Baba, T, Fujii, S, Marks, JR, Dressman, HK, Murphy, SK, and Berchuck, A. "Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype." Gynecol Oncol 116, no. 3 (March 2010): 556-562.  Full Text  Link to Item
    • Tebbit, CL, Zhai, J, Untch, BR, Ellis, MJ, Dressman, HK, Bentley, RC, Baker, JA, Marcom, PK, Nevins, JR, Marks, JR, and Olson, JA. "Novel tumor sampling strategies to enable microarray gene expression signatures in breast cancer: a study to determine feasibility and reproducibility in the context of clinical care." Breast Cancer Res Treat 118, no. 3 (December 2009): 635-643.  Full Text  Link to Item
    • Berchuck, A, Iversen, ES, Luo, J, Clarke, JP, Horne, H, Levine, DA, Boyd, J, Alonso, MA, Secord, AA, Bernardini, MQ, Barnett, JC, Boren, T, Murphy, SK, Dressman, HK, Marks, JR, and Lancaster, JM. "Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome." Clin Cancer Res 15, no. 7 (April 1, 2009): 2448-2455.  Full Text  Link to Item
    • Hsu, DS, Acharya, CR, Balakumaran, BS, Riedel, RF, Kim, MK, Stevenson, M, Tuchman, S, Mukherjee, S, Barry, W, Dressman, HK, Nevins, JR, Powers, S, Mu, D, and Potti, A. "Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer." Proc Natl Acad Sci U S A 106, no. 13 (March 31, 2009): 5312-5317.  Full Text  Link to Item
    • Boren, T, Xiong, Y, Hakam, A, Wenham, R, Apte, S, Chan, G, Kamath, SG, Chen, D-T, Dressman, H, and Lancaster, JM. "MicroRNAs and their target messenger RNAs associated with ovarian cancer response to chemotherapy." Gynecologic Oncology 113, no. 2 (2009): 249-255.  Full Text
    • Pilon, AM, Arcasoy, MO, Dressman, HK, Vayda, SE, Maksimova, YD, Sangerman, JI, Gallagher, PG, and Bodine, DM. "Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2." Mol Cell Biol 28, no. 24 (December 2008): 7394-7401.  Full Text  Link to Item
    • Haskins, KA, Russell, JF, Gaddis, N, Dressman, HK, and Aballay, A. "Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity." Dev Cell 15, no. 1 (July 2008): 87-97.  Full Text  Link to Item
    • Cragun, JM, Boren, T, Xiong, Y, Indermaur, M, Kamath, S, Cottrill, H, Balducci, L, Sayer, R, Dressman, HK, Berchuck, A, and Lancaster, J. "Gene expression determinants of ovarian cancer platinum-response in older women." J Clin Oncol 26, no. 15_suppl (May 20, 2008): 22059-.  Link to Item
    • Cragun, JM, Boren, T, Xiong, Y, Indermaur, M, Kamath, S, Cottrill, H, Balducci, L, Sayer, R, Dressman, HK, Berchuck, A, and Lancaster, J. "Gene expression determinants of ovarian cancer platinum-response in older women." JOURNAL OF CLINICAL ONCOLOGY 26, no. 15 (May 20, 2008).  Full Text  Link to Item
    • Hsu, SD, Acharya, CR, Riedel, RF, Redman, RC, Garman, KS, Dressman, HK, Ginsburg, G, Powers, S, Mu, D, and Potti, A. "Use of co-activation of lung cancer specific developmental pathway genes, TTF-1, NKX2-8, and PAX9, to predict prognosis and guide therapeutic strategies." JOURNAL OF CLINICAL ONCOLOGY 26, no. 15 (May 20, 2008).  Full Text  Link to Item
    • Acharya, CR, Hsu, DS, Anders, CK, Anguiano, A, Salter, KH, Walters, KS, Redman, RC, Tuchman, SA, Moylan, CA, Mukherjee, S, Barry, WT, Dressman, HK, Ginsburg, GS, Marcom, KP, Garman, KS, Lyman, GH, Nevins, JR, and Potti, A. "Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer." JAMA 299, no. 13 (April 2, 2008): 1574-1587.  Full Text  Link to Item
    • Meadows, SK, Dressman, HK, Muramoto, GG, Himburg, H, Salter, A, Wei, Z, Ginsburg, GS, Chao, NJ, Nevins, JR, and Chute, JP. "Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. (Published online)" PLoS One 3, no. 4 (April 2, 2008): e1912-.  Full Text  Open Access Copy  Link to Item
    • Salter, KH, Acharya, CR, Walters, KS, Redman, R, Anguiano, A, Garman, KS, Anders, CK, Mukherjee, S, Dressman, HK, Barry, WT, Marcom, KP, Olson, J, Nevins, JR, and Potti, A. "An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer. (Published online)" PLoS One 3, no. 4 (April 2, 2008): e1908-.  Full Text  Open Access Copy  Link to Item
    • Boren, T, Dressman, HK, Kamath, S, Wei, ZZ, Cragun, J, Humphrey, M, Chen, N, Xiong, Y, and Lancaster, JM. "MicroRNAs and their target messenger RNAs associated with the development of endometrial carcinoma." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S88-S89.  Link to Item
    • Boren, T, Dressman, HK, Wei, ZZ, Martino, MA, Zhang, T, Palmer, J, and Lancaster, JM. "Gene expression patterns in formalin-fixed, paraffin-embedded endometrial tissue associated with lymph node metastasis." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S89-S90.  Link to Item
    • Indermaur, MD, Boren, T, Cragun, J, Wenham, R, Aptel, S, Chan, G, Karnath, SG, Wei, Z, Dressman, HK, and Lancaster, JM. "Formalin-fixed, paraffin-embedded ovarian cancer gene expression signatures associated with platinum response." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S39-S39.  Link to Item
    • Indermaur, MD, Boren, T, Kamath, SG, Wei, Z, Wenham, R, Apte, S, Dressman, HK, and Lancaster, JM. "Targeted therapy to improve endometrial cancer response to doxorubicin." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S82-S82.  Link to Item
    • Boren, T, Xiong, Y, Hakam, A, Wenham, R, Apte, S, Wei, Z, Kamath, S, Chen, D-T, Dressman, H, and al, E. "MicroRNAs and their target messenger RNAs associated with endometrial carcinogenesis." Gynecologic Oncology 110, no. 2 (2008): 206-215.  Full Text
    • Hsu, DS, Balakumaran, BS, Acharya, CR, Vlahovic, V, Walters, KS, Garman, K, Anders, C, Riedel, RF, Lancaster, J, Harpole, D, Dressman, HK, Nevins, JR, Febbo, PG, and Potti, A. "Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer." J Clin Oncol 25, no. 28 (October 1, 2007): 4350-4357.  Full Text  Link to Item
    • Dressman, HK, Muramoto, GG, Chao, NJ, Meadows, S, Marshall, D, Ginsburg, GS, Nevins, JR, and Chute, JP. "Gene expression signatures that predict radiation exposure in mice and humans." PLoS Med 4, no. 4 (April 2007): e106-.  Full Text  Open Access Copy  Link to Item
    • Learn, CA, Grossi, PM, Schmittling, RJ, Xie, W, Mitchell, DA, Karikari, I, Wei, Z, Dressman, H, and Sampson, JH. "Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity." J Neuroimmunol 182, no. 1-2 (January 2007): 63-72.  Full Text  Link to Item
    • Learn, CA, Fecci, PE, Schmittling, RJ, Xie, W, Karikari, I, Mitchell, DA, Archer, GE, Wei, Z, Dressman, H, and Sampson, JH. "Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers." Clin Cancer Res 12, no. 24 (December 15, 2006): 7306-7315.  Full Text  Link to Item
    • Cheng, SH, Horng, C-F, West, M, Huang, E, Pittman, J, Tsou, M-H, Dressman, H, Chen, C-M, Tsai, SY, Jian, JJ, Liu, M-C, Nevins, JR, and Huang, AT. "Genomic prediction of locoregional recurrence after mastectomy in breast cancer." J Clin Oncol 24, no. 28 (October 1, 2006): 4594-4602.  Full Text  Link to Item
    • Lancaster, JM, Dressman, HK, Clarke, JP, Sayer, RA, Martino, MA, Cragun, JM, Henriott, AH, Gray, J, Sutphen, R, Elahi, A, Whitaker, RS, West, M, Marks, JR, Nevins, JR, and Berchuck, A. "Identification of genes associated with ovarian cancer metastasis using microarray expression analysis." Int J Gynecol Cancer 16, no. 5 (September 2006): 1733-1745.  Full Text  Link to Item
    • Gollob, JA, Sciambi, CJ, Peterson, BL, Richmond, T, Thoreson, M, Moran, K, Dressman, HK, Jelinek, J, and Issa, J-PJ. "Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma." Clin Cancer Res 12, no. 15 (August 1, 2006): 4619-4627.  Full Text  Link to Item
    • Dressman, HK, Bild, A, Garst, J, Harpole, D, and Potti, A. "Genomic signatures in non-small-cell lung cancer: targeting the targeted therapies." Curr Oncol Rep 8, no. 4 (July 2006): 252-257. (Review)  Link to Item
    • Chute, JP, Muramoto, GG, Dressman, HK, Wolfe, G, Chao, NJ, and Lin, S. "Molecular profile and partial functional analysis of novel endothelial cell-derived growth factors that regulate hematopoiesis." Stem Cells 24, no. 5 (May 2006): 1315-1327.  Full Text  Link to Item
    • Lux, A, Salway, F, Dressman, HK, Kröner-Lux, G, Hafner, M, Day, PJR, Marchuk, DA, and Garland, J. "ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression. (Published online)" BMC Cardiovasc Disord 6 (April 4, 2006): 13-.  Full Text  Link to Item
    • Damodaran, TV, Greenfield, ST, Patel, AG, Dressman, HK, Lin, SK, and Abou-Donia, MB. "Toxicogenomic studies of the rat brain at an early time point following acute sarin exposure." Neurochem Res 31, no. 3 (March 2006): 367-381.  Full Text  Link to Item
    • Potti, A, Bild, A, Dressman, HK, Lewis, DA, Nevins, JR, and Ortel, TL. "Gene-expression patterns predict phenotypes of immune-mediated thrombosis." Blood 107, no. 4 (February 15, 2006): 1391-1396.  Full Text  Link to Item
    • Damodaran, TV, Patel, AG, Greenfield, ST, Dressman, HK, Lin, SM, and Abou-Donia, MB. "Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure." Biochem Pharmacol 71, no. 4 (February 14, 2006): 497-520.  Full Text  Link to Item
    • Dressman, HK, Hans, C, Bild, A, Olson, JA, Rosen, E, Marcom, PK, Liotcheva, VB, Jones, EL, Vujaskovic, Z, Marks, J, Dewhirst, MW, West, M, Nevins, JR, and Blackwell, K. "Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy." Clin Cancer Res 12, no. 3 Pt 1 (February 1, 2006): 819-826.  Full Text  Link to Item
    • Bild, AH, Yao, G, Chang, JT, Wang, Q, Potti, A, Chasse, D, Joshi, M-B, Harpole, D, Lancaster, JM, Berchuck, A, Olson, JA, Marks, JR, Dressman, HK, West, M, and Nevins, JR. "Oncogenic pathway signatures in human cancers as a guide to targeted therapies." Nature 439, no. 7074 (January 19, 2006): 353-357.  Full Text  Link to Item
    • Dressman, HK, Barley-Maloney, L, Rowlette, L-L, Agris, PF, and Garcia-Blanco, MA. "Assessing incomplete deprotection of microarray oligonucleotides in situ." Nucleic Acids Res 34, no. 19 (2006): e131-.  Full Text  Link to Item
    • Boutlis, CS, Dressman, HK, Tjitra, E, Maniboey, H, Nevins, JR, Weinberg, JB, and Anstey, NM. "Patterns of gene expression that characterize outcomes of Plasmodium falciparum infection." AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 73, no. 6 (December 2005): 225-225.  Link to Item
    • Black, EP, Hallstrom, T, Dressman, HK, West, M, and Nevins, JR. "Distinctions in the specificity of E2F function revealed by gene expression signatures." Proc Natl Acad Sci U S A 102, no. 44 (November 1, 2005): 15948-15953.  Full Text  Link to Item
    • Gollob, JA, Sciambi, CJ, Huang, Z, and Dressman, HK. "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." Cancer Res 65, no. 19 (October 1, 2005): 8869-8877.  Full Text  Link to Item
    • Gollob, JA, Sciambi, CJ, Huang, ZQ, and Dressman, HK. "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." CANCER RESEARCH 65, no. 19 (October 1, 2005): 8869-8877.  Full Text  Link to Item
    • Delong, M, Yao, G, Wang, Q, Dobra, A, Black, EP, Chang, JT, Bild, A, West, M, Nevins, JR, and Dressman, H. "DIG--a system for gene annotation and functional discovery." Bioinformatics 21, no. 13 (July 1, 2005): 2957-2959.  Full Text  Link to Item
    • Martino, MA, Elahi, A, Sutphen, R, Klippel, C, Boren, T, Dressman, HK, Berchuck, A, and Lancaster, JM. "Expression analysis of genes involved in ovarian cancer metastasis." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 23, no. 16_suppl (June 2005): 5038-.
    • Berchuck, A, Iversen, ES, Lancaster, JM, Pittman, J, Luo, J, Lee, P, Murphy, S, Dressman, HK, Febbo, PG, West, M, Nevins, JR, and Marks, JR. "Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers." Clin Cancer Res 11, no. 10 (May 15, 2005): 3686-3696.  Full Text  Link to Item
    • Rich, JN, Hans, C, Jones, B, Iversen, ES, McLendon, RE, Rasheed, BKA, Dobra, A, Dressman, HK, Bigner, DD, Nevins, JR, and West, M. "Gene expression profiling and genetic markers in glioblastoma survival." Cancer Res 65, no. 10 (May 15, 2005): 4051-4058.  Full Text  Link to Item
    • Bammler, T, Beyer, RP, Bhattacharya, S, Boorman, GA, Boyles, A, Bradford, BU, Bumgarner, RE, Bushel, PR, Chaturvedi, K, Choi, D, Cunningham, ML, Deng, S, Dressman, HK, Fannin, RD, Farin, FM, Freedman, JH, Fry, RC, Harper, A, Humble, MC, Hurban, P, Kavanagh, TJ, Kaufmann, WK, Kerr, KF, Jing, L, Lapidus, JA, Lasarev, MR, Li, J, Li, Y-J, Lobenhofer, EK, Lu, X, Malek, RL, Milton, S, Nagalla, SR, O'malley, JP, Palmer, VS, Pattee, P, Paules, RS, Perou, CM, Phillips, K, Qin, L-X, Qiu, Y, and Quigley, SD et al. "Standardizing global gene expression analysis between laboratories and across platforms." Nat Methods 2, no. 5 (May 2005): 351-356.  Full Text  Link to Item
    • Bammler, T, Beyer, RP, Bhattacharya, S, Boorman, GA, Boyles, A, Bradford, BU, Bumgarner, RE, Bushel, PR, Chaturvedi, K, Choi, D, and al, E. "Standardizing global gene expression analysis between laboratories and across platforms." Nature Methods 2, no. 5 (2005): 1-6.  Full Text
    • Seo, D, Wang, T, Dressman, H, Herderick, EE, Iversen, ES, Dong, C, Vata, K, Milano, CA, Rigat, F, Pittman, J, Nevins, JR, West, M, and Goldschmidt-Clermont, PJ. "Gene expression phenotypes of atherosclerosis." Arterioscler Thromb Vasc Biol 24, no. 10 (October 2004): 1922-1927.  Full Text  Link to Item
    • Pittman, J, Huang, E, Dressman, H, Horng, C-F, Cheng, SH, Tsou, M-H, Chen, C-M, Bild, A, Iversen, ES, Huang, AT, Nevins, JR, and West, M. "Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes." Proc Natl Acad Sci U S A 101, no. 22 (June 1, 2004): 8431-8436.  Full Text  Link to Item
    • Berchuck, A, Iversen, ES, Lancaster, JM, Dressman, HK, West, M, Nevins, JR, and Marks, JR. "Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays." Am J Obstet Gynecol 190, no. 4 (April 2004): 910-925.  Full Text  Link to Item
    • Advani, AS, Dressman, HK, Quiroz, M, Taylor, GA, and Pendergast, AM. "Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis." Leuk Res 28, no. 3 (March 2004): 285-294.  Link to Item
    • Hashimoto, T, Lawton, MT, Wen, G, Yang, G-Y, Chaly, T, Stewart, CL, Dressman, HK, Barbaro, NM, Marchuk, DA, and Young, WL. "Gene microarray analysis of human brain arteriovenous malformations." Neurosurgery 54, no. 2 (February 2004): 410-423.  Link to Item
    • Lancaster, JM, Dressman, HK, Whitaker, RS, Havrilesky, L, Gray, J, Marks, JR, Nevins, JR, and Berchuck, A. "Gene expression patterns that characterize advanced stage serous ovarian cancers." J Soc Gynecol Investig 11, no. 1 (January 2004): 51-59.  Link to Item
    • Qin, L-X, Kerr, KF, Boyles, A, Dressman, HK, Freedman, JH, Li, Y-J, Malek, RL, Schwartz, DA, Slifer, S, Speer, MC, and al, E. "Empirical evaluation of data transformations and ranking statistics for microarray analysis." Nucleic Acids Research 32, no. 18 (2004): 5471-5479.  Full Text
    • Nevins, JR, Huang, ES, Dressman, H, Pittman, J, Huang, AT, and West, M. "Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction." Hum Mol Genet 12 Spec No 2 (October 15, 2003): R153-R157. (Review)  Full Text  Link to Item
    • Ellis, MJ, Rosen, E, Dressman, H, and Marks, J. "Neoadjuvant comparisons of aromatase inhibitors and tamoxifen: pretreatment determinants of response and on-treatment effect." J Steroid Biochem Mol Biol 86, no. 3-5 (September 2003): 301-307. (Review)  Link to Item
    • Huang, ES, Black, EP, Dressman, H, West, M, and Nevins, JR. "Gene expression phenotypes of oncogenic signaling pathways." Cell Cycle 2, no. 5 (September 2003): 415-417. (Review)  Link to Item
    • Black, EP, Huang, E, Dressman, H, Rempel, R, Laakso, N, Asa, SL, Ishida, S, West, M, and Nevins, JR. "Distinct gene expression phenotypes of cells lacking Rb and Rb family members." Cancer Res 63, no. 13 (July 1, 2003): 3716-3723.  Link to Item
    • Huang, E, Ishida, S, Pittman, J, Dressman, H, Bild, A, Kloos, M, D'Amico, M, Pestell, RG, West, M, and Nevins, JR. "Gene expression phenotypic models that predict the activity of oncogenic pathways." Nat Genet 34, no. 2 (June 2003): 226-230.  Full Text  Link to Item
    • Huang, E, Cheng, SH, Dressman, H, Pittman, J, Tsou, MH, Horng, CF, Bild, A, Iversen, ES, Liao, M, Chen, CM, West, M, Nevins, JR, and Huang, AT. "Gene expression predictors of breast cancer outcomes." Lancet 361, no. 9369 (May 10, 2003): 1590-1596.  Full Text  Link to Item
    • Huang, E, Ishida, S, Pittmann, J, Dressman, H, Bild, A, Kloos, M, D'Amico, M, Pestell, RG, West, M, and Nevins, JR. "Erratum: Gene expression phenotypic models that predict the activity of oncogenic pathways (Nature Genetics (2003) 34 (226-230))." Nature Genetics 34, no. 4 (2003): 465--.  Full Text
    • Bebenek, A, Carver, GT, Dressman, HK, Kadyrov, FA, Haseman, JK, Petrov, V, Konigsberg, WH, Karam, JD, and Drake, JW. "Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins." Genetics 162, no. 3 (November 2002): 1003-1018.  Link to Item
    • West, M, Blanchette, C, Dressman, H, Huang, E, Ishida, S, Spang, R, Zuzan, H, Olson, JA, Marks, JR, and Nevins, JR. "Predicting the clinical status of human breast cancer by using gene expression profiles." Proc Natl Acad Sci U S A 98, no. 20 (September 25, 2001): 11462-11467.  Full Text  Link to Item
    • Bebenek, A, Dressman, HK, Carver, GT, Ng, S, Petrov, V, Yang, G, Konigsberg, WH, Karam, JD, and Drake, JW. "Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69." J Biol Chem 276, no. 13 (March 30, 2001): 10387-10397.  Full Text  Link to Item
    • Dressman, HK, and Drake, JW. "Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene." J Bacteriol 181, no. 14 (July 1999): 4391-4396.  Link to Item
    • Paddison, P, Abedon, ST, Dressman, HK, Gailbreath, K, Tracy, J, Mosser, E, Neitzel, J, Guttman, B, and Kutter, E. "The roles of the bacteriophage T4 r genes in lysis inhibition and fine-structure genetics: a new perspective." Genetics 148, no. 4 (April 1998): 1539-1550.  Link to Item
    • Dressman, HK, Wang, CC, Karam, JD, and Drake, JW. "Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment." Proc Natl Acad Sci U S A 94, no. 15 (July 22, 1997): 8042-8046.  Link to Item
    • Humphries, JE, Dressman, HK, and Williams, ME. "Immunoglobulin gene rearrangement in multiple myeloma: limitations of Southern blot analysis." Hum Pathol 22, no. 10 (October 1991): 966-971.  Link to Item

  • Other Articles

    • Hsu, DS, Balakumaran, BS, Acharya, CR, Vlahovic, V, Walters, KS, Garman, K, Anders, C, Riedel, RF, Lancaster, J, Harpole, D, and al, E. "Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer (Journal of Clinical Oncology (2007) 25, (4350-4357))." Journal of Clinical Oncology 28, no. 35 (2010): 5229--.  Full Text
    • Andrew, B, Iversen, ES, Lancaster, JM, Dressman, HK, West, M, Nevins, JR, Marks, JR, and Miller, BE. "Prediction of optimal versus suboptimal cytoreduction of advanced-stage serious ovarian cancer with the use of microarrays." Women's Oncology Review 4, no. 3 (2004): 203-204.  Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.