Herbert Ira Hurwitz

Adjunct Professor in the Department of Medicine

Medicine, Medical Oncology

hurwi004@mc.duke.edu

Duke Box 3052, Durham, NC 27710

439 Seeley-Mudd Bldg, 10 Bryan Searle Drive, Duke University M, Durham, NC 27710

AT A GLANCE

Credentials
1. Education
2. Training & Certifications

Academic Experience
1. Current Appointments & Affiliations
2. Previous Appointments & Affiliations

Expertise

Research
1. Selected Grants

Publications
1. Selected Publications

Artistic Works / Events

Teaching

Advising & Mentoring

Recognition

Professional Activities

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Selected Grants

A randomized double blind studyh of Ruxolitinib or placebo in combination with Regorafenib in subjects with relapsed or refractory metastatic colorectal cancer.

Clinical TrialPrincipal Investigator · Awarded by Incyte Corporation · 2014 - 2019

A Companion study for patient who completed participation in a REGN2810 study

Clinical TrialPrincipal Investigator · Awarded by Regeneron Pharmaceuticals, Inc. · 2016 - 2018

A Phase 2 randomized proff of concept study of Nab-Paclitaxel/Gemcitabine alone and in combination with ACP-196 in subjects with previously untreated metastatic pancreatic cancer.

Clinical TrialPrincipal Investigator · Awarded by Acerta Pharma · 2015 - 2017

Preclinical and Human Correlative Studies of a Novel Bruton Tyronsine Kinase Inhibitor in Pancreatic Cancer

ResearchCo Investigator · Awarded by Department of Defense · 2016 - 2017

Biomarker Discovery to Direct Bevacizumab Therapy in Ovarian Cancer - Blood-based Angiome Profiling

ResearchCollaborator · Awarded by National Institutes of Health · 2014 - 2017

A randomized double blind studyh of Ruxolitinib or placebo in combination with Regorafenib in subjects with relapsed or refractory metastatic colorectal cancer.

Clinical TrialPrincipal Investigator · Awarded by Incyte Corporation · 2014 - 2019

A Companion study for patient who completed participation in a REGN2810 study

Clinical TrialPrincipal Investigator · Awarded by Regeneron Pharmaceuticals, Inc. · 2016 - 2018

A Phase 2 randomized proff of concept study of Nab-Paclitaxel/Gemcitabine alone and in combination with ACP-196 in subjects with previously untreated metastatic pancreatic cancer.

Clinical TrialPrincipal Investigator · Awarded by Acerta Pharma · 2015 - 2017

Preclinical and Human Correlative Studies of a Novel Bruton Tyronsine Kinase Inhibitor in Pancreatic Cancer

ResearchCo Investigator · Awarded by Department of Defense · 2016 - 2017

Biomarker Discovery to Direct Bevacizumab Therapy in Ovarian Cancer - Blood-based Angiome Profiling

ResearchCollaborator · Awarded by National Institutes of Health · 2014 - 2017

A randomized double bline phase 3 study of the JAK 1/2 inhibitor Ruxotinib or placebo in conbination with capecitbine in subjects with advanced or metastatic adenocarcinoma of the pancreas

Clinical TrialPrincipal Investigator · Awarded by Incyte Corporation · 2014 - 2017

The prevalence of MET gene amplification in metastatic colorectal cancer

ResearchInvestigator · Awarded by Amgen, Inc. · 2014 - 2016

Cancer Biology Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Cancer Institute · 1993 - 2016

Clinical Oncology Research Career Development Program

ResearchMentor · Awarded by National Institutes of Health · 2009 - 2015

Anti-VEGF in Tumors & Wounds: Efficacy vs Toxicity

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2012

Wound Angiogenesis as a Biomarker for Tumor Angiogenesis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2011

Biomarker Studies for Novel Anti-Cancer Agents

ResearchCo Investigator · Awarded by National Institutes of Health · 2003 - 2008

Partner-Assisted Emotional Disclosure for GI Cancer

ResearchPhysician · Awarded by National Institutes of Health · 2004 - 2008

Does NO mediate clinical anti-VEGF vascular effects

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2003 - 2006

New Clinical Biomarker for Cancer--Wound Angiogenesis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2000 - 2006