Scholars@Duke
Hutton Chapman

Hutton Chapman

Assistant Professor of Pediatrics
Pediatrics, Hematology-Oncology

Scholarly Works

Implementation Science Methodology for the Successful Introduction of High-Dose Methotrexate for the Treatment of Pediatric Mature B-Cell Non-Hodgkin Lymphoma in a Resource-Limited Setting.

Journal article Pediatr Blood Cancer · March 2026 BACKGROUND: Despite the excellent outcomes achieved for pediatric mature B-cell non-Hodgkin lymphoma (MB-NHL) in high-income countries, outcomes remain very poor in low- and middle-income countries. High-dose methotrexate (HD-MTX), which is highly efficaci ... Full text Link to item Cite

Prospective Psychometric Validation of the Swahili Translated and Adapted Pediatric Patient Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (Ped-PRO-CTCAE).

Journal article Meas Eval Cancer Care · December 2025 BACKGROUND: High quality clinical research is necessary in order to address the significant disparities in pediatric cancer outcomes seen in low- and middle-income countries (LMICs). Patient reported outcomes are now recognized as a critical part of many c ... Full text Link to item Cite

Abstract 18: Use of Patient Reported Outcomes to Assess Treatment Associated Toxicities for Pediatric Burkitt Lymphoma Patients in Tanzania

Conference Cancer Epidemiology, Biomarkers & Prevention · December 1, 2025 AbstractPurpose:Despite their increasing use in clinical practice and research in high resource settings, the use of patient re ... Full text Cite

Retrospective analysis of pediatric patients with Burkitt lymphoma treated in Tanzania following the implementation of the 2016 National Treatment Guidelines: Poor outcomes to current standard-of-care therapy.

Journal article Pediatr Blood Cancer · September 2024 BACKGROUND: Despite the excellent outcomes achieved in the treatment of pediatric Burkitt lymphoma (BL) in high-income countries (HICs), outcomes remain poor in low- and middle-income countries (LMICs). Efforts to improve BL outcomes in Tanzania included t ... Full text Link to item Cite

Development of an Evidence-Based Clinical Tool for Childhood Cancer Survivorship Care in Tanzania

Conference Blood · November 2, 2023 CONCLUSIONSThree in every four childhood cancer survivors experience late effects from treatment. As childhood cancer outcomes improve globally, it is important for providers to screen for these potential la ... Full text Cite

Analysis of Nutrition Status and Outcomes for Pediatric Patients with Burkitt Lymphoma Treated in Mwanza, Tanzania

Conference Blood · November 2, 2023 Introduction: Despite decades of improvement in outcomes for pediatric cancers in High-Income Countries (HICs), outcomes remain incredibly disparate as compared to those achieved in Low- and Middle-Income Countries (LMI ... Full text Cite

Abstract 33: Epidemiology, Diagnosis, and Outcomes of Pediatric Burkitt Lymphoma Patients Treated at Bugando Medical Centre in Mwanza, Tanzania

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2023 AbstractPurpose: Despite the significant improvement in outcomes over the last few decades for the treatment of pediatric Burkitt lymphoma, outcomes in sub-Saharan Africa remain poor, with an approximately 5 ... Full text Cite

Pediatric lymphoma patients in Malawi present with poor health-related quality of life at diagnosis and improve throughout treatment and follow-up across all Pediatric PROMIS-25 domains.

Journal article Pediatr Blood Cancer · October 2021 BACKGROUND: Patient-reportedoutcomes (PROs) that assess health-related quality of life (HRQoL) are increasingly important components of cancer care and research that are infrequently used in sub-Saharan Africa (SSA). METHODS: We administered the Chichewa P ... Full text Open Access Link to item Cite