https://orcid.org/0000-0002-9787-3371
Overview
I am the PI of the Cancer Initiation and Cancer Cell Behavior lab. Our research objective is to determine how cancer cells adapt and grow before cancer is diagnosed. Our lab is also part of the Center for Applied therapeutics where we share our models as tools for preclinical and translational research. To learn more about our research please visit the Cancer Initiation and Cancer Cell Behavior Lab's homepage.
Current Appointments & Affiliations
Associate Professor in Surgery
·
2025 - Present
Surgery, Surgical Sciences,
Surgery
Associate Professor of Cell Biology
·
2022 - Present
Cell Biology,
Basic Science Departments
Associate Professor in Pharmacology and Cancer Biology
·
2022 - Present
Pharmacology & Cancer Biology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2017 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
β-Arrestin condensates regulate G-protein-coupled receptor function.
Journal Article Nature · May 27, 2026 β-Arrestins 1 and 2 are multifunctional adaptor proteins1 that regulate the signalling of G-protein-coupled receptors (GPCRs), the largest class of receptors, which impact nearly all aspects of physiology and are one of the most common drug targets2. Altho ... Full text Link to item CiteCoSiDeX: A hyperspectral fluorescent protein resource for highly multiplexed imaging.
Preprint · May 14, 2025 Full text Link to item CitePrecision preclinical modeling to advance cancer treatment.
Journal Article J Natl Cancer Inst · April 1, 2025 A new era of cancer management is underway in which treatments are being developed for the entire continuum of the disease process. The availability of genetically engineered and naturally occurring preclinical models serves as instructive platforms for ev ... Full text Link to item CiteRecent Grants
The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program
ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028Role of PTEN in Homeostatic Repopulation in Kidney Transplantation
FellowshipCollaborator · Awarded by National Institutes of Health · 2026 - 2028Single Cell and Spatial Analysis of Lethal Breast Cancers
ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2028View All Grants
Education
University of Pittsburgh, School of Medicine ·
2009
Ph.D.