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Qingrong Jackie Wu

Professor of Radiation Oncology
Radiation Oncology
Box 3295 Med Ctr, Durham, NC 27710
201 Trent Drive, Box 3295, Durham, NC 27710

Scholarly Works - Conferences


Examining Radiation Therapy Planning Knowledge in Large Language Models

Conference Bcb 2025 Proceedings of the 16th ACM International Conference on Bioinformatics Computational Biology and Health Informatics · December 10, 2025 Personalized radiation therapy (RT) planning is crucial for minimizing toxicities. As large language models (LLMs) advance, it is vital to assess the RT planning knowledge across model types and sizes. We introduce a board-exam-style RT dataset and benchma ... Full text Cite

Clinical commissioning and introduction of an in-house artificial intelligence (AI) platform for automated head and neck intensity modulated radiation therapy (IMRT) treatment planning.

Conference J Appl Clin Med Phys · January 2025 BACKGROUND AND PURPOSE: To describe the clinical commissioning of an in-house artificial intelligence (AI) treatment planning platform for head-and-neck (HN) Intensity Modulated Radiation Therapy (IMRT). MATERIALS AND METHODS: The AI planning platform has ... Full text Link to item Cite

Repeatability of Radiomic Features Against Simulated Scanning Position Stochasticity Across Imaging Modalities and Cancer Subtypes: A Retrospective Multi-institutional Study on Head-and-Neck Cases

Conference Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics · January 1, 2022 We attempted to investigate the Radiomic feature (RF) repeatability and its agreements across imaging modalities and head-and-neck cancer (HNC) subtypes via image perturbations. Contrast-enhanced computed tomography (CECT), CET1-weight, T2-weight magnetic ... Full text Cite

Transfer learning for fluence map prediction in adrenal stereotactic body radiation therapy.

Conference Phys Med Biol · December 6, 2021 Objective:To design a deep transfer learning framework for modeling fluence map predictions for stereotactic body radiation therapy (SBRT) of adrenal cancer and similar sites that usually have a small number of cases.Approach:We developed a transfer learni ... Full text Link to item Cite

Collect Insights of an H&N IMRT Planning AI Agent Through Analyzing Relationships Between Fluence Map Prediction Error and the Corresponding Dosimetric Impacts.

Conference International journal of radiation oncology, biology, physics · November 2021 Purpose/objective(s)With many deep learning (DL) models being developed for clinical applications, it is important to understand their behavior and clinical consequence. This study aims to collect insights of the relationship between fluence map p ... Full text Cite

Assessing the Robustness and Performance of Artificial Intelligence Powered Planning Tools in Clinical Settings.

Conference International journal of radiation oncology, biology, physics · November 2021 Purpose/objective(s)Artificial intelligence (AI) driven tools have been maturing in automating the radiation treatment planning process. To prepare for clinical deployment of these tools, it is essential to understand their robustness in clinical ... Full text Cite

The Reduction of Computational Cost by Introducing Kernel Sparsity and Truncation Into IMRT Optimization.

Conference International journal of radiation oncology, biology, physics · November 2021 Purpose/objective(s)Applications involving AI and Machine Learning are rapidly improving our ability to plan treatments efficiently and effectively by aiding human planners and physicians during the iterative process of planning. These algorithms ... Full text Cite

Fluence Map Prediction for Fast Pancreas Stereotactic Body Radiation Therapy (SBRT) Planning via Deep Learning

Conference INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS · November 1, 2020 Link to item Cite

An Artificial Intelligence-Driven Agent for Rapid Head-and-Neck IMRT Plan Generation

Conference INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS · November 1, 2020 Link to item Cite

Clinical Experience of the Machine Learning-based Automated Treatment Planning Tool for Breast Radiotherapy

Conference INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS · November 1, 2020 Link to item Cite

Quantifying the Progression of Clinical Knowledge with a Knowledge-based Tradeoff Model

Conference INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS · November 1, 2020 Link to item Cite

Abstract P4-12-10: Clinical implementation of the machine learning-based automated treatment planning tool for whole breast radiotherapy

Conference Cancer Research · February 15, 2020 AbstractObjectives: The machine learning (ML)-based automated treatment planning tool has been developed and evaluated for whole breast radiotherapy. This study implemented the tool in clinic and compared pl ... Full text Cite

Dose Prediction for Prostate Radiation Treatment: Feasibility of a Distance-Based Deep Learning Model

Conference Proceedings 2019 IEEE International Conference on Bioinformatics and Biomedicine Bibm 2019 · November 1, 2019 This study aims to demonstrate the feasibility of using a novel distance-based representation of 3D CT-scan images to train a deep learning model for dose predictions in radiation treatment planning. The distance representation is inspired by previous know ... Full text Cite

Two Photon Dose Engines for Accurate and Fast Volumetric Modulated Arc Therapy

Conference 2019 Advances in Science and Engineering Technology International Conferences Aset 2019 · May 14, 2019 Two photon dose computation engines based on pencil beam models were customized to meet the requirements of high conformity and fast computation for Volumetric Modulated Arc Therapy (VMAT) plans. The first model is designed to run through first VMAT iterat ... Full text Cite

Incorporating Case-Based Reasoning for Radiation Therapy Knowledge Modeling: A Pelvic Case Study

Conference Technology in Cancer Research and Treatment · January 1, 2019 Knowledge models in radiotherapy capture the relation between patient anatomy and dosimetry to provide treatment planning guidance. When treatment schemes evolve, existing models struggle to predict accurately. We propose a case-based reasoning framework d ... Full text Cite

A Collimator Setting Optimization Algorithm for Dual-Arc Volumetric Modulated Arc Therapy in Pancreas Stereotactic Body Radiation Therapy

Conference Technology in Cancer Research and Treatment · January 1, 2019 Purpose: To optimize collimator setting to improve dosimetric quality of pancreas volumetric modulated arc therapy plan for stereotactic body radiation therapy. Materials and Methods: Fifty-five volumetric modulated arc therapy cases in stereotactic body r ... Full text Cite

Modeling and Prediction of SIB Prostate IMRT Plans

Conference International Journal of Radiation Oncology*Biology*Physics · November 2018 Full text Cite

Building a Successful Adaptive Radiotherapy Program

Conference MEDICAL PHYSICS · June 1, 2018 Link to item Cite

An Efficient Tool for Structure Label Harmonization

Conference International Journal of Radiation Oncology*Biology*Physics · October 2017 Full text Cite

Comparison of Photon and Proton Liver SBRT Plan Quality Affected by Daily Positioning and Anatomic Deviations

Conference International Journal of Radiation Oncology*Biology*Physics · October 2017 Full text Cite

Comparison of Photon and Proton Lung SBRT Treatment Impacted by Daily Positioning and Anatomic Deviations

Conference International Journal of Radiation Oncology*Biology*Physics · October 2017 Full text Cite

Improving Quality and Consistency in Clinical Trials via Knowledge-Based Planning, NRG Oncology RTOG 0631

Conference International Journal of Radiation Oncology*Biology*Physics · October 2017 Full text Cite

An Efficient Tool for Structure Label Harmonization

Conference MEDICAL PHYSICS · June 1, 2017 Link to item Cite

Outlier Identification in Radiation Therapy Knowledge Modeling: A Pelvic Planning Case Study

Conference International Journal of Radiation Oncology*Biology*Physics · October 2016 Full text Cite

Development of an Ultra-Fast, High-Quality Whole-Breast Radiation Therapy Treatment Planning System

Conference INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS · October 1, 2016 Link to item Cite

Outlier Identification in Radiation Therapy Knowledge Modeling: A Pelvic Planning Case Study

Conference INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS · October 1, 2016 Link to item Cite

SU-D-204-01: A Methodology Based On Machine Learning and Quantum Clustering to Predict Lung SBRT Dosimetric Endpoints From Patient Specific Anatomic Features.

Conference Med Phys · June 2016 PURPOSE: To develop a data-mining methodology based on quantum clustering and machine learning to predict expected dosimetric endpoints for lung SBRT applications based on patient-specific anatomic features. METHODS: Ninety-three patients who received lung ... Full text Link to item Cite

AAPM Task Group 263: Tackling Standardization of Nomenclature for Radiation Therapy

Conference International Journal of Radiation Oncology*Biology*Physics · November 2015 Full text Cite

A Rapid Learning Approach to the Knowledge Modeling of Radiation Therapy Planning

Conference International Journal of Radiation Oncology*Biology*Physics · November 2015 Full text Cite

Treatment Plan Quality Assurance for XXXX With Knowledge Engineering

Conference International Journal of Radiation Oncology*Biology*Physics · November 2015 Full text Cite

Evaluation of Lung IMRT Plans Quality Using a Knowledge-Based Engineering Tool

Conference International Journal of Radiation Oncology*Biology*Physics · November 2015 Full text Cite

TH‐EF‐BRD‐07: Knowledge Based Automatic Lung IMRT Planning with Non‐Coplanar Beams

Conference Medical Physics · June 2015 Purpose:We present a lung IMRT planning method which automatically determines both plan optimization objectives and beam configurations with non‐coplanar beams by analyzing patient‐specific anatomical information ... Full text Cite

SU‐E‐T‐537: Local Multi‐Criteria Optimization for Clinical Tradeoff Decision Guidance in RT Planning

Conference Medical Physics · June 2015 Purpose:We present a novel method for generating a local segment of Pareto surface around the best achievable plan predicted by a knowledge model. This local‐MCO will provide an efficient method to enable clinical ... Full text Cite

MO‐G‐304‐03: Development of Knowledge Models for IMRT Treatment Planning Utilizing a Rapid Learning Approach

Conference Medical Physics · June 2015 Purpose:We present an implementation of the knowledge‐based planning method utilizing a rapid learning approach which enables the accurate evolution of models as new data are collected during daily clinical practi ... Full text Cite

Knowledge modeling for computer aided treatment planning

Conference Ifmbe Proceedings · January 1, 2015 The purpose for this study is to develop robust and comprehensive knowledge models which can provide patient specific prediction of achievable dose distribution in radiation therapy plans for a wide range of cancer types. These models are useful tools to g ... Full text Cite

Knowledge based automatic beam angle determination for lung IMRT planning

Conference Ifmbe Proceedings · January 1, 2015 We present an efficient knowledge based automatic beam configuration determination method by utilizing patient-specific anatomy and tumor geometry information and a beam bouquet atlas. The proposed technique is based on learning the relationship between pa ... Full text Cite

A rapid learning approach for the knowledge modeling of radiation therapy plan

Conference Ifmbe Proceedings · January 1, 2015 The purpose of this study is to implement a rapid learning method to train the knowledge models to predict the organ-at-risk (OAR) dose sparing in radiation therapy (RT) based on an array of patient anatomical features. We also aim to establish the evaluat ... Full text Cite

Infrared image non-rigid registration based on regional information entropy demons algorithm

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2015 Infrared imaging fault detection which is treated as an ideal, non-contact, non-destructive testing method is applied to the circuit board fault detection. Since Infrared images obtained by handheld infrared camera with wide-Angle lens have both rigid and ... Full text Cite

Predictive Models for Assuring Quality and Consistency of Lung IMRT Plans Across Institutions in Cooperative Group Trials

Conference International Journal of Radiation Oncology*Biology*Physics · September 2014 Full text Cite

Automatic Determination of Beam Angles in Lung IMRT Planning

Conference International Journal of Radiation Oncology*Biology*Physics · September 2014 Full text Cite

Predicting Dose Distributions in Spinal SBRT Plans Using An Active Appearance Model (AAM)

Conference International Journal of Radiation Oncology*Biology*Physics · September 2014 Full text Cite

SBRT for Prostate + Seminal Vesicles: Fixed Margin or Online Adaptation

Conference International Journal of Radiation Oncology*Biology*Physics · September 2014 Full text Cite

SU‐F‐BRD‐10: Lung IMRT Planning Using Standardized Beam Bouquet Templates

Conference Medical Physics · June 2014 Purpose:We investigate the feasibility of choosing from a small set of standardized templates of beam bouquets (i.e., entire beam configuration settings) for lung IMRT planning to improve planning efficiency and q ... Full text Cite

Incorporating Trade-Off in Knowledge Modeling of Parotid Dose Sparing in Head and Neck IMRT

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Quality Evaluation of an Automatic VMAT Planning Method for Head-and-Neck Cancer Cases

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Effects of PET Reconstruction Parameters on Region-of-Interest Contouring by SUV Threshold

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Modeling Organs at Risk Dose Sparing in Head and Neck Tomotherapy and IMRT Plans: A Comparison Study

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Normal Tissue Toxicity Criteria in Radiation Therapy

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Quantitative Comparison of Knowledge-Guided IMRT Planning to Expert Planning for Prostate Cancer

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Intertechnique and Interinstitutional Modeling of the Dosimetry of Organs-at-Risk in Head and Neck IMRT Plans

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

WE-G-108-08: A Novel Technique for VMAT QA with EPID in Cine Mode On Varian TrueBeam.

Conference Med Phys · June 2013 PURPOSE: Volumetric modulated arc therapy (VMAT) is a relatively new treatment modality for dynamic photon radiation therapy. Pre-treatment quality assurance (QA) is necessary and many efforts have been taken to apply electronic portal imaging device (EPID ... Full text Link to item Cite

SU-E-T-560: A Method to Determine Optimal Dynamic MLC Parameters for Varian Truebeam with Millennium MLC and HDMLC.

Conference Med Phys · June 2013 PURPOSE: Correct MLC modeling is essential to the accurate IMRT delivery. Most TPSs use simplified models with parameters of leaf transmission (LT) and dynamic leaf gap (DLG). The common way to determine them is through extrapolation from measurements. In ... Full text Link to item Cite

SU-E-T-553: Measurement of Incident Electron Spots On TrueBeam.

Conference Med Phys · June 2013 PURPOSE: Lateral dimensions of the incident electron beam (spot sizes) are essential for accurate modelling of x-ray fields, especially for small field output factors and penumbrae. We present spot sizes measured on the Varian TrueBeam linac and propose an ... Full text Link to item Cite

SU-E-T-602: Dynamic Electron Arc Radiotherapy (DEAR): A Planning Study.

Conference Med Phys · June 2013 PURPOSE: Electron beam therapy is under-utilized in radiation treatment of cancer and has remained practically unchanged for decades. We propose a new technique, Dynamic Electron Arc Radiotherapy (DEAR) with synchronized couch motion. In DEAR, gantry rotat ... Full text Link to item Cite

TU‐C‐108‐07: Transmission Detector Array System for RT Delivery Monitoring: Validation Testing

Conference Medical Physics · January 1, 2013 Purpose: To quantify the influence of the gantry‐mounted Delta4‐AT detector array on beam quality, and the detection sensitivity to machine output and MLC position deviations. Methods: A Delta4‐AT prototype was attached to the accessory holder mount of a V ... Full text Cite

SU‐E‐T‐707: Evaluation of the Quality of Organs‐At‐Risk Dose Sparing in Anorectal and Prostate IMRT Plans

Conference Medical Physics · January 1, 2013 Purpose: To evaluate the quality of organs‐at‐risk (OARs) dose sparing in IMRT plans for anorectal and prostate cancer cases utilizing organ‐based knowledge models to predict OAR DVHs.MethodsThe quality of OAR dose sparing in IMRT plans are evaluated by or ... Full text Cite

TH‐C‐137‐08: Dosimetric Quality of An Automatic IMRT Planning Method for Head and Neck Cancer Cases

Conference Medical Physics · January 1, 2013 Purpose: To evaluate the dosimetric quality of an automatic IMRT planning method for Head and Neck (HN) cancer cases. Methods: Eighteen HN cancer patients are planned with nine equally spaced IMRT beams. The OAR dose sparing objectives for each plan (prima ... Full text Cite

SU‐E‐CAMPUS‐T‐05: Quality Evaluation of An Automatic VMAT Planning Method for Head and Neck Cancer Cases

Conference Medical Physics · January 1, 2013 Purpose: To evaluate the dosimetric quality of an automatic volumetric‐modulated arc therapy (VMAT) planning method for Head and Neck (HN) cancer cases. Methods: Eighteen HN cancer cases are planned automatically by 2‐arc VMAT. An OAR DVH prediction model ... Full text Cite

TU‐E‐108‐02: Dynamic Electron Arc Radiotherapy (DEAR): A Feasibility Study

Conference Medical Physics · January 1, 2013 Purpose: Electron beam therapy is under‐utilized in radiation treatment of cancer and has remained practically unchanged for decades. We propose a new technique, Dynamic Electron Arc Radiotherapy (DEAR) with synchronized couch motion. DEAR utilizes modulat ... Full text Cite

SU‐E‐T‐247: Design and Implement of the Radiation Therapy Case Conference Multi‐Media System Based On Windows Remote Desktop Feature

Conference Medical Physics · January 1, 2013 Purpose: To explore a method of using a computer system for multi‐media cases conference in clinical radiation oncology, in order to replace the traditional use of film images and paper. Methods: In a conference room without any treatment planning system(T ... Full text Cite

SU‐E‐T‐398: Case Study of Performance Testing Method for An Intensity Modulated Radiation Therapy Treatment Planning System Named RayStation

Conference Medical Physics · January 1, 2013 Purpose: Referring to the Standard of the Pharmaceutical Industry of the People's Republic of China “Performance and test methods for intensity modulated radiation therapy(IMRT) treatment planning system”, we will do a series of tests to an IMRT planning s ... Full text Cite

Prostate SBRT in 5 Fractions: Initial Report on Dosimetric Results and IGRT Experiences

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

SU-E-T-406: Online Image-Guidance for Prostate SBRT: Dosimetric Benefits and Margin Analysis.

Conference Med Phys · June 2012 PURPOSE: To evaluate the dosimetric benefits of online image guidance during prostate stereotactic body radiotherapy (SBRT) and the potential on margin reduction. METHODS: 28 prostate SBRT patients were retrospectively studied, each treated with 37Gy in 5 ... Full text Link to item Cite

SU-E-T-626: Individualized Trade-Off of Dose Coverage and Sparing in IMRT Planning.

Conference Med Phys · June 2012 PURPOSE: We present an evidence-based approach to quantifying the dose sparing trade-offs between different Organs-at-risk (OARs) and the trade-off between OAR dose sparing and target dose coverage in IMRT plans. METHODS: The interaction between dose spari ... Full text Link to item Cite

MO-D-BRB-10: Modeling Inter-Patient Variation of Organ-At-Risk Sparing in IMRT Plans: An Evidence-Based Plan Quality Evaluation.

Conference Med Phys · June 2012 PURPOSE: To develop a predictive model to assess the quality of critical organ dose sparing in IMRT plans by providing patient specific dose sparing references, based on an array of patient anatomical features and prior planning experience. METHODS: Contri ... Full text Link to item Cite

WE‐E‐BRB‐07: EPID Based Verification of Delivered Fluence for VMAT with High Angular Resolution

Conference Medical Physics · January 1, 2011 Purpose: In VMAT, the dose rate, MLC position, and gantry angle change simultaneously, it is important they follow their predefined trajectories to ensure correct dose delivery. Our purpose is to develop an efficient VMAT QA strategy using EPID that is cap ... Full text Cite

WE‐E‐301‐01: Practical Tips for VMAT Implementation

Conference Medical Physics · January 1, 2011 Volumetric modulated arc therapy (VMAT) is an arc‐based dose delivery approach that produces highly conformal dose distributions similar to those generated with static gantry intensity modulated radiation therapy. Like many existing IMRT approaches, this t ... Full text Cite

SU‐E‐T‐419: Clinical Protocol for the Use of Scrotal Shields in IMRT Treatment of Anal Cancer

Conference Medical Physics · January 1, 2011 Purpose: To implement a clinical protocol for the use of scrotal shields for anal cancer IMRT treatment. Methods and Results: (1) Simulation The patient is immobilized in a full‐body alpha‐cradle mold in the frog‐leg position. Further, the mold is built up ... Full text Cite

MO‐D‐BRC‐07: Reducing Artifacts in Cone‐Beam CT Images Caused by the Presence of An Array Used for Tracking Transponders during Radiotherapy

Conference Medical Physics · January 1, 2011 Purpose: To compare two methods for reducing artifacts in cone‐beam CT (CBCT) images caused by the presence of an electromagnetic array used for tracking transponders during radiotherapy. Methods: A pelvis phantom was imaged using a gantry mounted CBCT sys ... Full text Cite

SU‐E‐T‐23: Ontological Representation of Radiation Treatment Guidelines

Conference Medical Physics · January 1, 2011 Purpose: To develop a Radiation Treatment Guidelines Ontology (RTGO) that represents the concepts, knowledge, and guidelines in radiation therapy using a formal and computable framework. This ontology will serve as the foundation of a decision support syst ... Full text Cite

SU‐E‐T‐99: A Patient Specific QA Protocol for Verification of 4D Dosimetry

Conference Medical Physics · January 1, 2011 Purpose: Presently, there is no patient specific dosimetric QA for radiation treatment of moving targets. Here we present a patient specific QA protocol for verification of 4D dosimetry delivered to a moving target in SBRT of lung and liver tumors. Methods ... Full text Cite

SU‐E‐T‐773: Dosimetric and Geometric Evaluation of a Hybrid Strategy of Online Image Guidance and Offline Adaptive Planning for Prostate Cancer Radiotherapy

Conference Medical Physics · January 1, 2011 Purpose: In fractionated radiotherapy of prostate cancer, both online and offline image‐guided strategies have been used to manage uncertainties such as setup errors and organ motions. In general, online image guidance is more effective than offline image ... Full text Cite

SU‐E‐T‐782: A Novel Geometric Index to Evaluate Image Guidance Strategies for Prostate Cancer Adaptive Radiotherapy

Conference Medical Physics · January 1, 2011 Purpose: Margin has been commonly used to evaluate different image guidance (IG) strategies in prostate cancer radiotherapy. However, it becomes cumbersome when applied to adaptive radiotherapy. In this study, a new index, cumulative index of target volume ... Full text Cite

SU‐E‐T‐270: A “Rolling Average” Adaptive Planning Technique to Compensate Target Volume Changes in Prostate Cancer Radiotherapy

Conference Medical Physics · January 1, 2011 Purpose: In external beam radiotherapy of prostate cancer, the inter‐fractional motion can have several forms: changes in position, shape and volume. The changes in position can be corrected by online image guidance, while the shape and volume changes are ... Full text Cite

SU‐C‐110‐01: Strategies for Online Plan Re‐Optimization: Objective Settings and Starting Stage

Conference Medical Physics · January 1, 2011 Purpose: To find the most robust strategies of objective setting and starting stage for online plan re‐optimization, so it can be automatically executed within 1 min while providing high quality adaptive plans. Methods: 10 prostate cancer patients, each wi ... Full text Cite

SU‐E‐T‐854: Key Anatomical Factors Influencing OAR Dose‐Volume Distribution in Prostate IMRT Plans

Conference Medical Physics · January 1, 2011 Purpose: To identify the key factors of patient anatomy that influence the optimal dose volume histograms (DVHs) for the organs‐at‐risk (OARs) and to explore the tradeoffs between different OAR sparing goals. Methods: 88 prostate IMRT plans were studied re ... Full text Cite

TH‐E‐BRB‐05: Modeling the Correlation Between OAR Dose Sparing and Patient's Anatomy in Head and Neck IMRT

Conference Medical Physics · January 1, 2011 Purpose: To summarize the knowledge of the dependence of organ‐at‐risk (OAR) dose‐volume distribution on patient's anatomy by machine learning techniques from a database of previous expert plans. Methods: 35 head‐and‐ neck IMRT plans were studied retrospec ... Full text Cite

SU‐E‐J‐05: Analysis of Setup Errors on CBCT‐Based Image‐Guided Radiation Therapy Patients

Conference Medical Physics · January 1, 2011 Purpose: To evaluate setup errors of 192 patients undergone image‐guided radiation therapy (IGRT) using kilovoltage (kV) cone beam CT (CBCT). Methods: A retrospective study has been carried out for 192 patients treated with intensity‐modulated radiation th ... Full text Cite

Intensity Modulated Arc Therapy: Effective and Efficient End-to-end Patient Specific Quality Assurance

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

SU‐GG‐T‐136: Treatment Plans Comparison with Static‐Gantry IMRT and RapidArcTM for Head‐And‐Neck Cancers Involving Cervical Lymph Nodes

Conference Medical Physics · January 1, 2010 Purpose: To compare the dosimetric results and treatment efficiency of intensity modulated arc therapy using RapidArc™ to static‐gantry IMRT plans for conventional fractionation treatment of head‐and‐neck cancer. Materials and Methods: This study evaluated ... Full text Cite

SU‐GG‐T‐225: Gantry‐Angle Dependence of a 2D Ion Chamber Array for IMAT QA

Conference Medical Physics · January 1, 2010 Purpose: Gantry‐angle dependence of dose measurement for intensity‐modulated arc therapy (IMAT) quality assurance (QA) using a two‐dimensional ion chamber array may be significant. A new device, the gantry angle sensor, has been provided to compensate for ... Full text Cite

SU‐GG‐T‐137: Similarities between Static and Rotational Intensity Modulated Plans

Conference Medical Physics · January 1, 2010 Purpose: To explore similarities between intensity modulated radiotherapy (IMRT) and intensity modulated arc therapy (IMAT) techniques in the context of the number of multi‐leaf collimator (MLC) segments required to achieve plan objectives, the major facto ... Full text Cite

SU‐GG‐T‐583: Dosimetric Comparison of Anisotropic Analytical and Pencil Beam Convolution Algorithms in Breast Cancer Radiation Treatment Planning

Conference Medical Physics · January 1, 2010 Purpose: The anisotropic analytical algorithm (AAA) has been shown to provide more accurate dose calculation due to 3D scatter and inhomogeneity corrections than the pencil beam convolution algorithm (PBC) for inhomogeneous anatomical regions such as lung ... Full text Cite

SU‐EE‐A1‐03: Arc Modulated Radiation Therapy Based on Linear Models

Conference Medical Physics · January 1, 2010 Purpose: The challenge for implementing promising Arc Modulated Radiation Therapy (AMRT) is its effectiveness of treatment planning tools to find optimal multileaf collimator (MLC) sequence and the fluence map. This study provides a new approach to the abo ... Full text Cite

WE‐B‐BRA‐03: Adaptive Image‐Guided Radiation Therapy (AIGRT) for Hypo‐Fractionated Prostate Cancer Treatment

Conference Medical Physics · January 1, 2010 Purpose: The large fractional dose of hypo‐fractionated prostate treatment requires high accuracy of daily treatment delivery. This study analyzes the performance of an adaptive IGRT (AIGRT) technique, which combines image guidance and adaptive re‐planning ... Full text Cite

TU‐E‐BRB‐03: A Planning Quality Evaluation Tool for Adaptive IMRT Treatment Based on Machine Learning

Conference Medical Physics · January 1, 2010 Purpose: To monitor the quality of adaptive IMRT plans, especially dose sparing for the organs‐at‐risk (OARs), a plan evaluation tool is developed to predict the dose volume histogram (DVH) based on patient's anatomical information and a database of high q ... Full text Cite

TU‐B‐BRA‐01: Total Body Irradiation (TBI): Looking from Differrent Angles

Conference Medical Physics · January 1, 2010 Purpose: To explore the new degree of freedom of VMAT to design a novel technique for TBI, in which patient is positioned supine/prone on the floor and an arc field is delivered with variable dose rate and/or dynamic collimators. Method and Materials: A fo ... Full text Cite

Imaging Guided Stereotactic Radiosurgery and its Accuracy Compared to Frame-based Localization

Conference International Journal of Radiation Oncology*Biology*Physics · November 2009 Full text Cite

Intensity Modulated Radiation Therapy (IMRT) for Anal Cancer: The Duke University Experience

Conference International Journal of Radiation Oncology*Biology*Physics · November 2009 Full text Cite

Hybrid IGRT Technique for Prostate Hypofractionation

Conference International Journal of Radiation Oncology*Biology*Physics · November 2009 Full text Cite

Comparing Static vs. Rotational IMRT for Spine Body Radiotherapy

Conference International Journal of Radiation Oncology*Biology*Physics · November 2009 Featured Publication Full text Cite

SU‐FF‐T‐309: Quality Assurance for Imaging Guided Stereotactic RadioSurgery with Novalis Tx™ System

Conference Medical Physics · January 1, 2009 Purpose: To present QA measurements over extended periods at our institute and recommend a QA program for image‐guided radiosurgery on Novalis Tx system. Method and Materials: Novalis Tx system is developed based on a Trilogy linear accelerator featuring B ... Full text Cite

SU‐FF‐T‐130: Radiotherapy Treatment Plans with RapidArc for Head‐And‐Neck Cancer

Conference Medical Physics · January 1, 2009 Purpose: The purpose of this study is to compare RapidArc plans and conventional IMRT plans for head‐and‐neck cancer treatment involving bilateral nodes. Methods and Materials: This study included 10 locally advanced head‐and‐neck cancer patients. The plan ... Full text Cite

SU‐EE‐A3‐02: Imaging Guided Frameless Stereotactic RadioSurgery Using CBCT 6D Image Registration and 6D Couch On Novalis Tx™ System

Conference Medical Physics · January 1, 2009 Purpose: To investigate localization accuracy for image‐guided frameless stereotactic‐radiosurgery (IG‐SRS) using CBCT 6D image registration and 6D‐couch on Novalis Tx system. Method and Materials: Novalis Tx system is a powerful radiosurgery system featur ... Full text Cite

SU‐FF‐T‐548: Comparison of Cone‐Beam CT and Frame‐Based Localizations for Stereotactic Radiosurgery with Fixed Head Rings and Removable Frames

Conference Medical Physics · January 1, 2009 Objectives: To compare localization accuracy using both conventional frame‐based localizers and cone‐beam CT (CBCT) images for stereotactic radiosurgery (SRS). Methods: A SRS geometric phantom was used to verify the localization accuracy based on a SRS loc ... Full text Cite

SU‐FF‐T‐301: Clinical Implementation and Commission of Volumetric Modulated Arc Therapy

Conference Medical Physics · January 1, 2009 Purpose Volumetric modulated arc therapy (VMAT) is a rotational IMRT modality that combines dose rate modulation with gantry and MLC motion, thereby increasing the complexity of IMRT delivery. Effective implementation of this technology is still quite new ... Full text Cite

SU‐FF‐T‐314: Patient‐Specific Quality Assurance Techniques for RapidArc Radiotherapy

Conference Medical Physics · January 1, 2009 Purpose: To develop a patient‐specific quality assurance protocol for RapidArc™ radiotherapy. Method and Materials: Following the commissioning of RapidArc™ treatment delivery, we tested several methods of patient‐specific quality assurance (QA). Ion chamb ... Full text Cite

SU‐FF‐J‐56: Integrating Real‐Time Tracking Into Image Guided Radiation Therapy for Prostate Cancer Treatment

Conference Medical Physics · January 1, 2009 Purpose: To investigate how a real‐time tracking technique, based on implanted transponders, could be effectively integrated into the current process for image‐guided radiation treatment of prostate cancer. Method and Materials: Current prostate IGRT proce ... Full text Cite

TH‐A‐211A‐01: Digital Tomosynthesis for Target Localization

Conference Medical Physics · January 1, 2009 Any deviation between treated and planned volumes for 3‐D conformal therapy, such as IMRT, may cause an adverse clinical outcome. It is therefore critical to minimize all potential deviations using an on‐board (or real‐time) imaging procedure immediately p ... Full text Cite

SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment

Conference Medical Physics · January 1, 2009 Purpose: Volumetric modulated arc treatment (VMAT) reduces treatment time over static beam intensity modulated treatment (IMRT) by delivering IMRT using arcs. This clinical study evaluates the feasibility of using VMAT for spine stereotactic body radiother ... Full text Cite

SU‐FF‐J‐55: Acceptance Testing and Quality‐Assurance Protocols for the Calypso® 4D Localization System™ and Q‐Fix®/Calypso® Couchtop

Conference Medical Physics · January 1, 2009 Purpose: To develop quality‐assurance (QA) protocols for the Calypso® 4D Localization System including acceptance testing, commissioning, daily QA, monthly QA, and annual QA. Method and Materials: The following acceptance testing/commissioning/QA protocols ... Full text Cite

SU‐FF‐J‐105: Is Offline Adaptive Planning Necessary for Online Image‐Guided Radiotherapy of Prostate Cancer?

Conference Medical Physics · January 1, 2009 Purpose: In online image‐guided radiation therapy of prostate cancer, the inter‐fractional translational motion is corrected at each fraction. However, rotation and deformation can only be accounted for using planning margins. Offline adaptive strategy has ... Full text Cite

SU‐FF‐T‐80: Hybrid Image Guided Radiation Therapy for Hypofractionated Prostate IMRT: Feasibility Study

Conference Medical Physics · January 1, 2009 Purpose: In prostate IGRT employing hypofractionation, two methods are commonly used: patient re‐positioning and re‐planning. We propose a hybrid IGRT technique in this study. The dosimetric benefits and efficiency improvement of the technique is quantitat ... Full text Cite

SU‐FF‐T‐574: Radiotherapy Treatment Plans with RapidArc for Prostate Cancer Involving Seminal Vesicles

Conference Medical Physics · January 1, 2009 Purpose: The purpose of this report is to compare RapidArc plans and conventional IMRT plans for prostate cancer involving seminal vesicles. Methods and Materials: This study included 10 patients. The planning‐target volume (PTV) contained the prostate and ... Full text Cite

MO‐D‐BRB‐08: A Hybrid Strategy of Offline Adaptive Planning and Online Image Guidance for Prostate Cancer Radiotherapy

Conference Medical Physics · January 1, 2009 Purpose: In online image‐guided radiotherapy of prostate cancer, the setup error and inter‐fractional motion is eliminated through pre‐treatment imaging and couch correction at each fraction. However, the rotation and deformation is not corrected and only ... Full text Cite

SU‐FF‐J‐95: Dosimetric Margin Assessment for Rigid Setup Error by CBCT for HN‐IMRT

Conference Medical Physics · January 1, 2009 Purpose: High dose gradients offered by IMRT increase the sensitivity of treatment to setup errors compared to conventional treatments. We evaluated the dosimetric effects of setup error on HN‐IMRT using actual patient CBCT measurements. The purposes were ... Full text Cite

SU‐FF‐T‐102: Is Average Fractional Dose Representative of Cumulative Dose for HN‐IMRT?

Conference Medical Physics · January 1, 2009 Purpose: Use of on‐board cone‐beam CT (CBCT) imaging during HN‐IMRT treatment course allows for calculation and reconstruction of the dose delivered to the patient daily. The purpose of this study was to investigate whether the average fractional dose repr ... Full text Cite

SU‐FF‐T‐223: A New IMRT/RapidArc QA Procedure Utilizing MLC Dynalog Files

Conference Medical Physics · January 1, 2009 Purpose: To develop a quick and efficient patient‐specific QA procedure for both IMRT and RapidArc using MLC dynalog files. Method and Materials: MLC dynalog files record both planned and actual MLC leaf positions, actual fractional MU and gantry angle. Th ... Full text Cite

Dosimetrical Evaluation of SRS/SBRT Techniques

Conference International Journal of Radiation Oncology*Biology*Physics · September 2008 Full text Cite

Can Cone Beam CT Replace Frame-based Localization for Stereotactic Radiosurgery?

Conference International Journal of Radiation Oncology*Biology*Physics · September 2008 Full text Cite

A Novel Digital Tomosynthesis (DTS) Reconstruction Method using Prior Information and a Deformation Model

Conference International Journal of Radiation Oncology*Biology*Physics · September 2008 Full text Cite

Stereotactic Body Radiosurgery of the Spine: The Duke Experience

Conference International Journal of Radiation Oncology*Biology*Physics · September 2008 Full text Cite

Dosimetrical Evaluation of an Online Adaptive IMRT Technique

Conference International Journal of Radiation Oncology*Biology*Physics · September 2008 Full text Cite

On-board CBCT Observations Support using Adaptive Non-uniform Custom Margins for Prostate IGRT

Conference International Journal of Radiation Oncology*Biology*Physics · September 2008 Full text Cite

SU‐GG‐T‐446: Dosimetric Characteristics of High Definition Multi‐Leaf Collimator

Conference Medical Physics · January 1, 2008 Purpose: A new type of high‐definition multi‐leaf collimator (HD 120 MLC, Varian Medical Systems) is being introduced into clinical practice to improve the conformality of stereotactic radiation therapy and radiosurgery. Its leaf width at isocenter is 2.5 ... Full text Cite

SU‐GG‐T‐454: Localization Accuracy of Cone‐Beam CT Guided Radiosurgery as Investigated Utilizing a Geometric Phantom

Conference Medical Physics · January 1, 2008 Purpose: While the advantage of imaging guidance with cone beam CT (CBCT) guided radiosurgery is obvious, the localization accuracy of CBCT guided radiosurgery still remains a concern. This study utilized a geometric phantom with known target positions to ... Full text Cite

SU‐GG‐J‐81: Efficacy of Patient Setup Correction Procedure in Prostate Radiotherapy

Conference Medical Physics · January 1, 2008 Purpose: Using an on‐board cone‐beam CT (CBCT) based statistical margin model to determine whether a prostate center‐of‐mass (COM) based translation correction procedure can significantly reduce the CTV‐to‐PTV margin required for prostate patients who were ... Full text Cite

SU‐GG‐I‐52: Conversion of On‐Board Digital TomoSynthesis (DTS) to HU Values

Conference Medical Physics · January 1, 2008 Purpose: To investigate a method to convert the pixel values of DTS images to HU values with reference HU values from CT images. Method and Materials: This study included CT and DTS images of two phantoms (Catphan and a chest phantom) and three patients (p ... Full text Cite

SU‐GG‐I‐53: The Impact of Scan Angles On the Visibility of Anatomy in On‐Board Digital Tomosynthesis (DTS) Images for Head and Neck Cancer Patients: A Single‐Observer Study

Conference Medical Physics · January 1, 2008 Purpose: To assess the impact of scan angles on the visibility of anatomy in on‐board digital tomosynthesis (DTS) images as a means to optimize this technique. Method and Materials: Head and neck cancer patients undergoing intensity‐modulated radiotherapy ... Full text Cite

SU‐GG‐T‐53: Integrating An Online Adaptive IMRT Process to the Prostate IGRT

Conference Medical Physics · January 1, 2008 Purpose: To investigate the feasibility of a novel online IMRT re‐optimization process. This online process can be an integral part to the current prostate IGRT paradigm to augment the existing patient alignment techniques for cases with complex daily orga ... Full text Cite

SU‐GG‐T‐13: Fast Seed Localization On MR Images For Post‐Prostate Implant Dosimetry

Conference Medical Physics · January 1, 2008 Purpose: Accurate and reliable post‐prostate implant dosimetric analysis requires optimal identification of the seeds on CT and optimal description of soft tissues on MRI. We present a fast seed localization technique for MRI that is also robust from motio ... Full text Cite

SU‐GG‐T‐54: On‐Line Adaptive IMRT for Prostate Cancer

Conference Medical Physics · January 1, 2008 Purpose: This study proposes a novel on‐line IGRT technique that can modify the original IMRT plan to match with the “anatomy‐of‐the‐day” within few minutes. The performance of this technique is compared with current on‐line IGRT strategies using bone/soft ... Full text Cite

SU‐GG‐J‐47: Clinical Implementation of An Integrated System for Image‐Guided Radiation Therapy (IGRT) and Adaptive Radiation Therapy (ART)

Conference Medical Physics · January 1, 2008 Purpose: It is critical that image‐guided radiation therapy (IGRT) and adaptive radiation therapy (ART) are performed with clearly defined goals without abusing the technologies. This study illustrates the current integrated system that provides efficient ... Full text Cite

Clinical Evaluation of Digital Tomosynthesis for Target Localization in Breath-Hold Liver Treatment

Conference International Journal of Radiation Oncology*Biology*Physics · November 2007 Full text Cite

The Effect of Scan Angle on Target Localization Accuracy Using Digital Tomosynthesis

Conference International Journal of Radiation Oncology*Biology*Physics · November 2007 Full text Cite

SU‐FF‐J‐58: Clinical Evaluation Using Digital Tomosynthesis for Positioning Verification of Breath‐Hold Liver Treatment

Conference Medical Physics · January 1, 2007 Purpose: To demonstrate clinical feasibility of generating digital tomosynthesis (DTS) in a single breath‐hold (BH) period compared to multiple BH periods for CBCT acquisition and to examine on‐board BH‐DTS as an efficient alternative to BH‐CBCT for target ... Full text Cite

SU‐FF‐J‐48: Three‐Dimensional MRI and Cone‐Beam CT Matching for Localization of Prostate Cancer Treatment

Conference Medical Physics · January 1, 2007 PURPOSES: There is a growing interest using MRI only for prostate cancer treatment planning. This study is aimed to investigate clinical feasibility of matching 3D planning MRI to on‐board cone‐beam CT (CBCT) images for target localization. Materials and M ... Full text Cite

On-line adaptive planning system for prostate IMRT treatment

Conference INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS · January 1, 2007 Link to item Cite

SU‐FF‐T‐252: Improvement of Localization Accuracy by Using 3D Cone Beam CT for Stereotactic Body Radiation Therapy of Liver, Lung and Spine Lesions

Conference Medical Physics · January 1, 2007 Purpose: To compare treatment isocenter placement based on OBI 2D kV imaging and OBI 3D‐CBCT imaging for patients undergoing SBRT, and compare the CBCT based isocenter shifts among liver, lung and spine lesions. Material and Methods: 119 SBRT fractions wer ... Full text Cite

SU‐FF‐T‐326: On the Use of Ice as a Water‐Equivalent Solid Medium for Brachytherapy Dosimetry Measurement

Conference Medical Physics · January 1, 2007 Purpose: It is well‐known that fluctuation in chemical compositions can lead to significant errors in the dosimetry of low‐energy brachytherapy sources using the traditional “water‐equivalent” solid phantoms. The aim of this work was to investigate the fea ... Full text Cite

SU‐FF‐T‐14: A High MU Efficiency Dynamic MLC Leaf Sequencing Algorithm

Conference Medical Physics · January 1, 2007 Purpose: MU efficiency is a major figure of merit for dMLC leaf sequencing. However, leaf sequencing is often generated with focus on other constraints and the MU efficiency is taken as a byproduct. This work is to develop a new dMLC leaf sequencing algori ... Full text Cite

TH‐D‐AUD‐07: The Impact of SBRT Treatment Techniques On Dose Delivery in Presence of Organ Motion and Deformation

Conference Medical Physics · January 1, 2007 Purpose: The impact of organ motion and deformation has been studied for conventional radiation therapy. The cumulative dose is usually a blurred version of the static plan after motion‐induced hot and cold spots average out over a large number of fraction ... Full text Cite

TH‐E‐M100F‐07: Amplitude Gated Breath‐Hold Treatment for Upper Abdominal Lesions with On Board Imaging Guidance

Conference Medical Physics · January 1, 2007 Purpose: To apply on‐boardmdash;image (OBI) guided amplitude gating for breath‐hold treatment and to assess treatment margin adequacy by analyzing the isocenter placement based on orthogonal 2D kV radiographs and 3D cone‐beam CT (CBCT) acquired under ampli ... Full text Cite

SU‐DD‐A3‐04: On‐Line Re‐Optimization of Prostate IMRT Plans for Image Guided Adaptive Radiation Therapy

Conference Medical Physics · January 1, 2007 Purpose: This study proposes a novel on‐line adaptive planning technique for the prostate treatment by directly re‐optimizing the IMRT plan based on both the “anatomy‐of‐the‐day” and the original plan information. Method & Materials: Using a commercial tre ... Full text Cite

WE‐E‐M100F‐01: 3D Interfraction Position Verification for Patients Undergoing Partial Breast Irradiation: Comparing Digital Tomosynthesis to Cone‐Beam CT

Conference Medical Physics · January 1, 2007 Purpose: This clinical study evaluates digital tomosynthesis (DTS) technology for daily imaging guidance for partial breast irradiation (PBI) and compares its positioning accuracy to the 3D CBCT technique. Compared to CBCT, DTS offers lower imaging dose an ... Full text Cite

TU‐EE‐A3‐03: Performing Concurrent Kilovoltage Imaging While Delivering Megavoltage Treatment Beams

Conference Medical Physics · January 1, 2007 Purpose: To investigate the clinical feasibility of performing concurrent kilovoltage (kV) x‐ray imaging while the patient at the treatment position was irradiated by megavoltage (MV) beams. Method and Materials: Anatomical visibility and contrast details ... Full text Cite

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Conference International Journal of Radiation Oncology*Biology*Physics · November 2006 Full text Cite

1028

Conference International Journal of Radiation Oncology*Biology*Physics · November 2006 Full text Cite

SU‐FF‐T‐263: Imaging with Brachytherapy Sources

Conference Medical Physics · January 1, 2006 Purpose: To demonstrate the concept of 2D projection and 3D volumetric imaging using brachytherapy treatment sources in patient prior to or during treatment. Method and Materials: As shown Figure 1, an Ir‐192 HDR catheter is placed at 15 cm depth (a reason ... Full text Cite

SU‐FF‐T‐151: Conservation of Integrated Reference Air Kerma

Conference Medical Physics · January 1, 2006 Purpose: To demonstrate the conservation rule of the integrated reference air kerma (IRAK). Method and Materials: For a brachytherapy photon source whose radial dose functions is flat over the clinical distance range, the dose falls off with the inverse sq ... Full text Cite

SU‐EE‐A1‐04: Verifying Internal Target Volume Using Cone‐Beam CT for Stereotactic Body Radiotherapy Treatment

Conference Medical Physics · January 1, 2006 Purpose: The internal target volume (ITV) could be determined using 4D CT simulation images and be verified in the treatment room using on‐board cone‐beam CT (CBCT) since the CBCT projection images are acquired over approximately 10 breathing cycles. This ... Full text Cite

SU‐FF‐J‐86: Intra‐ and Inter‐Breath‐Hold Position Variations for OBI Guided Amplitude Gating Treatment with Breath Hold

Conference Medical Physics · January 1, 2006 Purpose: We have applied OBI guidance together with a respiratory gating system to effectively control patient positioning for amplitude gating treatment with breath hold. The deep inspiration breath‐hold treatment has been proven effective in reducing the ... Full text Cite

MO‐A‐224C‐01: Daily Localization I: KV/CBCT

Conference Medical Physics · January 1, 2006 Daily target localization is a critical step to secure accurate delivery for 3‐D conformal radiation therapy and intensity‐modulated radiation therapy. One emerging technology using in‐room kilovoltage (kV) imaging has shown to be very promising for target ... Full text Cite

SU‐FF‐J‐16: A Tool for Off‐Line Review of 3D Target Verification and Localization with Cone‐Beam Computed Tomography

Conference Medical Physics · January 1, 2006 Purpose: To implement a clinical tool for off‐line review of Cone‐Beam Computed Tomography (CBCT) based 3D target verification and localization. Methods and Materials: An in‐house 3D target localization and verification tool is being developed to allow phy ... Full text Cite

SU‐FF‐J‐02: 3D Target Localization Using Cone‐Beam CT for Head and Neck IMRT Patients

Conference Medical Physics · January 1, 2006 Purpose: To evaluate clinical effectiveness of target localization using cone‐beam CT (CBCT) for H&N IMRT treatment. Method and Materials: All H&N patients treated with an IRB approved protocol were imaged on the first day of treatment and weekly thereafte ... Full text Cite