Scholars@Duke
Qingrong Jackie Wu

Qingrong Jackie Wu

Professor of Radiation Oncology
Radiation Oncology
jackie.wu@duke.edu
Box 3295 Med Ctr, Durham, NC 27710
201 Trent Drive, Box 3295, Durham, NC 27710

Featured Works

Quantitative analysis of the factors which affect the interpatient organ-at-risk dose sparing variation in IMRT plans.

Journal article Med Phys · November 2012 Featured Publication PURPOSE: The authors present an evidence-based approach to quantify the effects of an array of patient anatomical features of the planning target volumes (PTVs) and organs-at-risk (OARs) and their spatial relationships on the interpatient OAR dose sparing ... Full text Link to item Cite

Volumetric-modulated arc therapy: effective and efficient end-to-end patient-specific quality assurance.

Journal article Int J Radiat Oncol Biol Phys · April 1, 2012 Featured Publication PURPOSE: To explore an effective and efficient end-to-end patient-specific quality-assurance (QA) protocol for volumetric modulated arc radiotherapy (VMAT) and to evaluate the suitability of a stationary radiotherapy QA device (two-dimensional [2D] ion cha ... Full text Link to item Cite

Development of a 4D dosimetry simulation system in radiotherapy

Journal article International Journal of Biomedical Engineering and Technology · January 1, 2012 Featured Publication 4D CT image sets are used to encode patient-organ motion and to calculate the dose delivered during each respiratory phase. The dose-per-phase is summarised to the total dose via deformable registration. The system incorporates the actual beam parameters a ... Full text Cite

Adaptive prostate IGRT combining online re-optimization and re-positioning: a feasibility study.

Journal article Phys Med Biol · March 7, 2011 Featured Publication In prostate radiation therapy, inter-fractional organ motion/deformation has posed significant challenges on reliable daily dose delivery. To correct for this issue, off-line re-optimization and online re-positioning have been used clinically. In this pape ... Full text Link to item Cite

A planning quality evaluation tool for prostate adaptive IMRT based on machine learning.

Journal article Med Phys · February 2011 Featured Publication PURPOSE: To ensure plan quality for adaptive IMRT of the prostate, we developed a quantitative evaluation tool using a machine learning approach. This tool generates dose volume histograms (DVHs) of organs-at-risk (OARs) based on prior plans as a reference ... Full text Link to item Cite

An image-guided technique for planning and verification of supine craniospinal irradiation.

Journal article J Appl Clin Med Phys · January 31, 2011 Featured Publication We present a technique for planning and verification of craniospinal treatment with the patient in the supine position. Treatment delivery and verification is streamlined through the use of modern imaging techniques. Treatments use two lateral brain fields ... Full text Link to item Cite

Arc-modulated radiation therapy based on linear models.

Journal article Phys Med Biol · July 7, 2010 Featured Publication This paper reports an inverse arc-modulated radiation therapy planning technique based on linear models. It is implemented with a two-step procedure. First, fluence maps for 36 fixed-gantry beams are generated using a linear model-based intensity-modulated ... Full text Link to item Cite

Similarities between static and rotational intensity-modulated plans.

Journal article Phys Med Biol · January 7, 2010 Featured Publication The aim of this study was to explore similarities between intensity-modulated radiotherapy (IMRT) and intensity-modulated arc therapy (IMAT) techniques in the context of the number of multi-leaf collimator (MLC) segments required to achieve plan objectives ... Full text Link to item Cite

Volumetric arc intensity-modulated therapy for spine body radiotherapy: comparison with static intensity-modulated treatment.

Journal article Int J Radiat Oncol Biol Phys · December 1, 2009 Featured Publication PURPOSE: This clinical study evaluates the feasibility of using volumetric arc-modulated treatment (VMAT) for spine stereotactic body radiotherapy (SBRT) to achieve highly conformal dose distributions that spare adjacent organs at risk (OAR) with reduced t ... Full text Link to item Cite

Comparing Static vs. Rotational IMRT for Spine Body Radiotherapy

Conference International Journal of Radiation Oncology*Biology*Physics · November 2009 Featured Publication Full text Cite

The impact of respiratory motion and treatment technique on stereotactic body radiation therapy for liver cancer.

Journal article Med Phys · April 2008 Featured Publication Stereotactic body radiation therapy (SBRT), which delivers a much higher fractional dose than conventional treatment in only a few fractions, is an effective treatment for liver metastases. For patients who are treated under free-breathing conditions, howe ... Full text Link to item Cite

Real-time inverse planning for Gamma Knife radiosurgery.

Journal article Med Phys · November 2003 Featured Publication The challenges of real-time Gamma Knife inverse planning are the large number of variables involved and the unknown search space a priori. With limited collimator sizes, shots have to be heavily overlapped to form a smooth prescription isodose line that co ... Full text Link to item Cite

Morphology-guided radiosurgery treatment planning and optimization for multiple isocenters.

Journal article Med Phys · October 1999 Featured Publication This work merges two distinct fields, 3D morphology and ionizing radiation dosimetry, to solve the problem of 3D-treatment planning and optimization in stereotactic radiosurgery. In Leksell Gamma Knife radiosurgery, dose delivery is based on the unit "shot ... Full text Link to item Cite