James Patrick Daubert

Journal article Eur Heart J · July 2011 Featured Publication AIMS: There are no data regarding the differential response to cardiac resynchronization therapy with defibrillator (CRT-D) by the aetiology of cardiomyopathy in mildly symptomatic patients. We evaluated the outcome of patients enrolled in MADIT-CRT by isc ... Full text Link to item Cite

Left ventricular lead position and clinical outcome in the multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy (MADIT-CRT) trial.

Journal article Circulation · March 22, 2011 Featured Publication BACKGROUND: An important determinant of successful cardiac resynchronization therapy for heart failure is the position of the left ventricular (LV) pacing lead. The aim of this study was to analyze the impact of the LV lead position on outcome in patients ... Full text Link to item Cite

Effectiveness of Cardiac Resynchronization Therapy by QRS Morphology in the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT).

Journal article Circulation · March 15, 2011 Featured Publication BACKGROUND: This study aimed to determine whether QRS morphology identifies patients who benefit from cardiac resynchronization therapy with a defibrillator (CRT-D) and whether it influences the risk of primary and secondary end points in patients enrolled ... Full text Link to item Cite

Percutaneous intravascular defibrillator: preliminary data and many questions.

Journal article Heart Rhythm · February 2011 Featured Publication Full text Link to item Cite

Pulmonary vein contraction before and after radiofrequency ablation for atrial fibrillation.

Journal article J Cardiovasc Electrophysiol · February 2011 Featured Publication UNLABELLED: INTRODUCTION: Cardiovascular magnetic resonance imaging (cMRI) may provide a noninvasive method to test for pulmonary vein (PV) isolation after ablation for atrial fibrillation (AF) by detecting changes in PV contraction. METHODS: PV contract ... Full text Link to item Cite

Catheter ablation of atrial fibrillation in the elderly.

Journal article Curr Opin Cardiol · January 2011 Featured Publication PURPOSE OF REVIEW: Atrial fibrillation is increasingly prevalent among older adults and is a major contributor to morbidity in this population due to associated strokes, heart failure, and quality of life impairment. Catheter ablation for atrial fibrillati ... Full text Link to item Cite

Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest.

Journal article Resuscitation · December 2010 Featured Publication INTRODUCTION: Therapeutic hypothermia has been shown to provide neuroprotection and improved survival in patients suffering a cardiac arrest. We report outcomes of consecutive patients receiving therapeutic hypothermia for cardiac arrest and describe predi ... Full text Link to item Cite

Prevalence and clinical characteristics associated with left atrial appendage thrombus in fully anticoagulated patients undergoing catheter-directed atrial fibrillation ablation.

Journal article J Cardiovasc Electrophysiol · August 1, 2010 Featured Publication INTRODUCTION: Catheter-directed atrial fibrillation (AF) ablation is contraindicated among patients with left atrial appendage (LAA) thrombus. The prevalence of LAA thrombus among fully anticoagulated patients undergoing AF ablation is unknown. METHODS AND ... Full text Link to item Cite

Can we improve the identification of ventricular scar to guide substrate-based ventricular tachycardia ablation?

Journal article J Cardiovasc Electrophysiol · June 1, 2010 Featured Publication Full text Link to item Cite

Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation.

Journal article Pacing Clin Electrophysiol · May 2010 Featured Publication BACKGROUND: Recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA) has been well established and is in part related to left atrial (LA) size. The purpose of this study was to assess the predictive capability of LA diameter (LA ... Full text Link to item Cite

Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria.

Journal article Eur Heart J · April 2010 Featured Publication BACKGROUND: In 1994, an International Task Force proposed criteria for the clinical diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) that facilitated recognition and interpretation of the frequently nonspecific clinical featu ... Full text Link to item Cite

Cardiac-resynchronization therapy for the prevention of heart-failure events.

Journal article N Engl J Med · October 1, 2009 Featured Publication BACKGROUND: This trial was designed to determine whether cardiac-resynchronization therapy (CRT) with biventricular pacing would reduce the risk of death or heart-failure events in patients with mild cardiac symptoms, a reduced ejection fraction, and a wid ... Full text Link to item Cite

Rationale and design for the Defibrillators to Reduce Risk by Magnetic Resonance Imaging Evaluation (DETERMINE) trial.

Journal article J Cardiovasc Electrophysiol · September 2009 Featured Publication BACKGROUND: Cardiac magnetic resonance imaging (CMR) can accurately determine infarct size. Prior studies using indirect methods and CMR to assess infarct size have shown that patients with larger myocardial infarctions have worse prognoses. Implantable ca ... Full text Link to item Cite

Why are (only) some infarcted hearts arrhythmogenic?

Journal article J Am Coll Cardiol · July 7, 2009 Featured Publication Full text Link to item Cite

Arrhythmogenic right ventricular cardiomyopathy/dysplasia clinical presentation and diagnostic evaluation: results from the North American Multidisciplinary Study.

Journal article Heart Rhythm · July 2009 Featured Publication BACKGROUND: Prior reports on patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) focused on individuals with advanced forms of the disease. Data on the diagnostic performance of various testing modalities in newly identified in ... Full text Link to item Cite

Ventricular arrhythmia inducibility predicts subsequent ICD activation in nonischemic cardiomyopathy patients: a DEFINITE substudy.

Journal article Pacing Clin Electrophysiol · June 2009 Featured Publication OBJECTIVES: We evaluated whether electrophysiologic (EP) inducibility predicts the subsequent occurrence of spontaneous ventricular tachycardia (VT) or ventricular fibrillation (VF) in the Defibrillators in Nonischemic Cardiomyopathy Treatment Evaluation ( ... Full text Link to item Cite

Mystery of biphasic defibrillation waveform efficacy is it calcium?

Journal article J Am Coll Cardiol · September 2, 2008 Featured Publication Full text Link to item Cite

Congenital long QT syndrome: considerations for primary care physicians.

Journal article Cleve Clin J Med · August 2008 Featured Publication Congenital long QT syndrome is an inherited disorder of cardiac repolarization that predisposes to syncope and to sudden death from polymorphic ventricular tachycardia. The disorder should be suspected when the electrocardiogram shows characteristic QT abn ... Full text Link to item Cite

Acute and long-term efficacy and safety of catheter cryoablation of the cavotricuspid isthmus for treatment of type 1 atrial flutter.

Journal article Heart Rhythm · July 2008 Featured Publication BACKGROUND: Atrial flutter (AFL) is commonly treated by radiofrequency catheter ablation. Catheter-based cryoablation may be an effective alternative with potential advantages. OBJECTIVE: The purpose of this study was to study the acute and long-term safet ... Full text Link to item Cite

Inappropriate implantable cardioverter-defibrillator shocks in MADIT II: frequency, mechanisms, predictors, and survival impact.

Journal article J Am Coll Cardiol · April 8, 2008 Featured Publication OBJECTIVES: This study sought to identify the incidence and outcome related to inappropriate implantable cardioverter-defibrillator (ICD) shocks, that is, those for nonventricular arrhythmias. BACKGROUND: The MADIT (Multicenter Automatic Defibrillator Impl ... Full text Link to item Cite

Mechanisms of ventricular fibrillation initiation in MADIT II patients with implantable cardioverter defibrillators.

Journal article Pacing Clin Electrophysiol · February 2008 Featured Publication BACKGROUND: The availability of stored intracardiac electrograms from implantable defibrillators (ICDs) has facilitated the study of the mechanisms of ventricular tachyarrhythmia onset. This study aimed to determine the patterns of initiation of ventricula ... Full text Link to item Cite

Role of magnetic resonance imaging in arrhythmogenic right ventricular dysplasia: insights from the North American arrhythmogenic right ventricular dysplasia (ARVD/C) study.

Journal article Am Heart J · January 2008 Featured Publication BACKGROUND: Prior reports describing magnetic resonance (MR) imaging abnormalities in arrhythmogenic right ventricular dysplasia (ARVD/C) were limited by nonuniform inclusion criteria. The aim of our study was to define the prevalence, sensitivity, and spe ... Full text Link to item Cite

Risks and challenges of implantable cardioverter-defibrillators in young adults.

Journal article Prog Cardiovasc Dis · 2008 Featured Publication The clinical use of the implantable cardioverter-defibrillator (ICD) is well established to prevent sudden death in patients with left ventricular dysfunction due to coronary artery disease and dilated cardiomyopathy, and its use has saved thousands of liv ... Full text Link to item Cite

Ventricular arrhythmia storms in postinfarction patients with implantable defibrillators for primary prevention indications: a MADIT-II substudy.

Journal article Heart Rhythm · November 2007 Featured Publication BACKGROUND: Much of prognostic implications of ventricular arrhythmia storms remain unclear. OBJECTIVE: We evaluated the risk associated with electrical storm in patients with defibrillators in the Multicenter Automatic Defibrillator Implantation Trial II ... Full text Link to item Cite

Iatrogenic left atrial tachycardias: where are we?

Journal article J Am Coll Cardiol · October 30, 2007 Featured Publication Full text Link to item Cite

Improved survival associated with prophylactic implantable defibrillators in elderly patients with prior myocardial infarction and depressed ventricular function: a MADIT-II substudy.

Journal article J Cardiovasc Electrophysiol · August 2007 Featured Publication INTRODUCTION: We aim to evaluate the mortality benefit from defibrillator therapy in eligible elderly patients. Effective primary prevention of sudden cardiac death with implantable cardioverter defibrillators is well demonstrated in patients with coronary ... Full text Link to item Cite

Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy.

Journal article JAMA · July 25, 2007 Featured Publication CONTEXT: Recently, the implantable cardioverter-defibrillator (ICD) has been promoted for prevention of sudden death in hypertrophic cardiomyopathy (HCM). However, the effectiveness and appropriate selection of patients for this therapy is incompletely res ... Full text Link to item Cite

Role of implantable cardioverter defibrillator therapy in patients with long QT syndrome.

Journal article Am Heart J · April 2007 Featured Publication Long QT syndrome (LQTS) is one of several primary electrical disorders or hereditary arrhythmia syndromes along with the short QT syndrome, Brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia. Since its initial recognition in 1957 b ... Full text Link to item Cite

Predictive value of ventricular arrhythmia inducibility for subsequent ventricular tachycardia or ventricular fibrillation in Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients.

Journal article J Am Coll Cardiol · January 3, 2006 Featured Publication UNLABELLED: In the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II, implantable cardioverter-defibrillator (ICD)-randomized patients underwent electrophysiologic testing. Both inducible and noninducible patients received an ICD. We correl ... Full text Link to item Cite

Safety of transvenous cardiac resynchronization system implantation in patients with chronic heart failure: combined results of over 2,000 patients from a multicenter study program.

Journal article J Am Coll Cardiol · December 20, 2005 Featured Publication OBJECTIVES: The purpose of this study was to evaluate the safety of implanting a cardiac resynchronization therapy (CRT) system. BACKGROUND: Clinicians and patients require data on the safety of the CRT implant procedure to estimate procedural risk. METHOD ... Full text Link to item Cite

Factors influencing appropriate firing of the implanted defibrillator for ventricular tachycardia/fibrillation: findings from the Multicenter Automatic Defibrillator Implantation Trial II (MADIT-II).

Journal article J Am Coll Cardiol · November 1, 2005 Featured Publication OBJECTIVES: The purpose of this study was to prospectively examine the role of clinical, laboratory, echocardiographic, and electrophysiological variables as predictors of appropriate initial implantable cardioverter-defibrillator (ICD) therapy for ventric ... Full text Link to item Cite

Safety and efficacy of flecainide in subjects with Long QT-3 syndrome (DeltaKPQ mutation): a randomized, double-blind, placebo-controlled clinical trial.

Journal article Ann Noninvasive Electrocardiol · October 2005 Featured Publication BACKGROUND: We conducted a study of chronic therapy with flecainide versus placebo in a small group of LQT-3 patients with the DeltaKPQ deletion to evaluate the safety and efficacy of flecainide in this genetic disorder. In vitro studies have shown that fl ... Full text Link to item Cite

The clinical implications of cumulative right ventricular pacing in the multicenter automatic defibrillator trial II.

Journal article J Cardiovasc Electrophysiol · April 2005 Featured Publication INTRODUCTION: This study was designed to assess whether right ventricular pacing in the implantable cardioverter defibrillator (ICD) arm of the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II was associated with an unfavorable outcome. ME ... Full text Link to item Cite

Performance of a new cardiac cryoablation system in the treatment of cavotricuspid valve isthmus-dependent atrial flutter.

Journal article Pacing Clin Electrophysiol · January 2005 Featured Publication We sought to evaluate prospectively the safety and efficacy of cryothermal energy to ablate typical atrial flutter (AFL). Ablation of cardiac tissue using cryothermal energy has recently been developed as an alternative to radiofrequency energy, which may ... Full text Link to item Cite

Prophylactic defibrillator implantation in patients with nonischemic dilated cardiomyopathy.

Journal article N Engl J Med · May 20, 2004 Featured Publication BACKGROUND: Patients with nonischemic dilated cardiomyopathy are at substantial risk for sudden death from cardiac causes. However, the value of prophylactic implantation of an implantable cardioverter-defibrillator (ICD) to prevent sudden death in such pa ... Full text Link to item Cite

Implantable cardioverter defibrillator in high-risk long QT syndrome patients.

Journal article J Cardiovasc Electrophysiol · April 2003 Featured Publication INTRODUCTION: Implantable cardioverter defibrillators (ICDs) are increasingly being used in high-risk long QT syndrome (LQTS) patients, but there are limited data regarding clinical experience with this therapeutic modality. The aim of this study is to des ... Full text Link to item Cite

MADIT-II: clinical implications.

Journal article Card Electrophysiol Rev · December 2002 Featured Publication The MADIT-II trial showed that in patients with a prior myocardial infarction and ejection fraction Full text Link to item Cite

Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction.

Journal article N Engl J Med · March 21, 2002 Featured Publication BACKGROUND: Patients with reduced left ventricular function after myocardial infarction are at risk for life-threatening ventricular arrhythmias. This randomized trial was designed to evaluate the effect of an implantable defibrillator on survival in such ... Full text Link to item Cite

Response of relatively refractory canine myocardium to monophasic and biphasic shocks.

Journal article Circulation · December 1991 Featured Publication BACKGROUND: Certain biphasic waveforms defibrillate at lower energies than monophasic waveforms, although the mechanism is unknown. METHODS AND RESULTS: The relative ability of monophasic and biphasic shocks to stimulate partially refractory myocardium was ... Full text Link to item Cite