Current Appointments & Affiliations
Associate Professor in Medicine
·
2025 - Present
Medicine, Hematology,
Medicine
Assistant Research Professor in Cell Biology
·
2019 - Present
Cell Biology,
Basic Science Departments
Member of Duke Molecular Physiology Institute
·
2016 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Senior Fellow in the Center for the Study of Aging
·
2016 - Present
Center for the Study of Aging and Human Development,
Institutes and Centers
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Glutamine-driven reductive TCA cycle metabolism supports aged muscle stem cell function via de novo lipogenesis.
Journal Article Nat Aging · May 2026 Sarcopenia and the age-related decline in muscular strength and regenerative capacity contribute directly to loss of autonomy, greater risk for hospitalization and healthcare utilization. One contributing cellular phenotype associated with skeletal muscle ... Full text Link to item CiteThe exercise hormone irisin has neuroprotective effects in a mouse model of multiple sclerosis.
Journal Article Nat Metab · May 2026 Aerobic exercise is a disease-modifying intervention in multiple sclerosis (MS) that ameliorates several progressive neurological symptoms in people with MS. Here we show that the exercise hormone irisin mediates neuroprotective effects of exercise in the ... Full text Link to item CitePhosphoproteomics Modifications in Women with Rheumatoid Arthritis─Application of Web-Based Software to Enhance Data Visualization.
Journal Article J Proteome Res · September 5, 2025 Individuals with rheumatoid arthritis (RA) are at increased risk of functional disability, cardiovascular disease, and obesity, all of which are influenced by dysregulated skeletal muscle. This pilot study aims to identify phosphoproteomics changes in RA s ... Full text Link to item CiteRecent Grants
Fibro/Adipogenic Progenitor Metabolic Reprogramming for Age-Related Muscle Fibrosis
ResearchAdvisor · Awarded by National Institute on Aging · 2024 - 2029Endocrinology and Metabolism Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029Mechanisms linking the Branched-Chain alpha-Keto Acid regulatory network to the pathogenesis of NASH
ResearchCo Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2023 - 2028View All Grants
Education
University of South Carolina, Columbia ·
2010
Ph.D.
Florida State University ·
2005
M.S.