Overview
I am a physician-scientist with clinical and research expertise in lung transplantation and advanced lung disease, in particular idiopathic pulmonary fibrosis (IPF). My research aims to advance scientific knowledge related to the clinical and genetic risk factors underlying the development of lung fibrosis including that occurring in chronic lung transplant rejection and diseases leading to transplant, such as IPF. I also have an interest in understanding how the airway epithelial response to injury impacts lung repair, fibrosis, and tissue immunity.
Current Appointments & Affiliations
Associate Professor of Medicine
·
2023 - Present
Medicine, Pulmonary, Allergy, and Critical Care Medicine,
Medicine
Member in the Duke Clinical Research Institute
·
2012 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Basiliximab induction immunosuppression and lung transplant outcomes: Propensity analysis in a multicenter cohort.
Journal Article J Heart Lung Transplant · June 2025 BACKGROUND: Basiliximab induction immunosuppression is increasingly employed in lung transplant recipients despite limited prospective evidence to support its use in this population. We sought to determine the relationship between basiliximab induction and ... Full text Link to item CiteEvaluating the performance of a resampling approach for internally validating the association between a time-dependent binary indicator and time-to-event outcome.
Journal Article J Biopharm Stat · April 27, 2025 Identifying clinical or biological risk factors for disease plays a critical role in enabling earlier disease diagnosis, prognostic outcomes assessment, and may inform disease prevention or monitoring practices. One framework commonly examined is understan ... Full text Link to item CiteIdentification and validation of a threshold for early posttransplant bronchoalveolar fluid hyaluronan that distinguishes lung recipients at risk for chronic lung allograft dysfunction.
Journal Article J Heart Lung Transplant · March 2025 BACKGROUND: Few tools exist for the early identification of patients at risk for chronic lung allograft dysfunction (CLAD). We previously showed hyaluronan (HA), a matrix molecule that regulates lung inflammation and fibrosis, accumulates in bronchoalveola ... Full text Link to item CiteRecent Grants
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029EFC17801_9085-0205 SANOFI Pro00113681
Clinical TrialPrincipal Investigator · Awarded by Sanofi US · 2024 - 2028Lung Transplant Clinical Trial Network (LT-CTN)
ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2028View All Grants
Education, Training & Certifications
University of Colorado, School of Medicine ·
2005
M.D.