Jamie Lynn Todd | Scholars@Duke

Jamie Lynn Todd
Assistant Professor of Medicine

I am a physician-scientist with clinical and research expertise in lung transplantation and advanced lung disease, in particular idiopathic pulmonary fibrosis (IPF). My research aims to advance scientific knowledge related to the clinical and genetic risk factors underlying the development of lung fibrosis including that occurring in chronic lung transplant rejection and diseases leading to transplant, such as IPF. I also have an interest in understanding how the airway epithelial response to injury impacts lung repair, fibrosis, and tissue immunity.

Current Appointments & Affiliations

Assistant Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2021
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2012

Contact Information

Box 103002, MSRB II, Durham, NC 27710
Suite 2073, MSRB II, 106 Research Drive, Durham, NC 27710
jamie.todd@duke.edu (919) 681-1353

Background
Education, Training, & Certifications
- Fellow in Pulmonary Medicine, Medicine, Duke University 2008 - 2009
- Resident, Medicine, Duke University 2005 - 2008
- M.D., University of Colorado School of Medicine 2005
Previous Appointments & Affiliations
- Assistant Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2015 - 2020
- Medical Instructor in the Department of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2012 - 2015
- Medical Instructor in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2009 - 2010
Research
Selected Grants
- Lung Transplant Clinical Trial Network (LT-CTN) awarded by National Institutes of Health 2021 - 2028
- Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER) awarded by National Institutes of Health 2022 - 2026
- CTOT Long-Term Extension Study awarded by Cystic Fibrosis Foundation 2019 - 2024
- Early Posttransplant Intragraft Hyaluronan as an Independent Biomarker of CLAD Risk awarded by Cystic Fibrosis Foundation 2022 - 2024
- Club cell secretory protein to distinguish chronic allograft dysfunction risk in lung transplant recipients awarded by Cystic Fibrosis Foundation 2023
- Genetics of Acute Rejection and Chronic Lung Allograft Dysfunction awarded by Cystic Fibrosis Foundation 2019 - 2022
- Chronic Lung Allograft Dysfunction awarded by AstraZeneca AB 2019 - 2021
- Cell-free DNA in the Blood and Lung Allograft Fluid: Understanding Association with Acute Rejection in Lung Transplant Recipients awarded by CareDx, Inc. 2019 - 2021
- Club Cells and CCSP in the pathogenesis of CLAD/spatial transcriptomics awarded by Icahn School of Medicine at Mount Sinai 2020 - 2021
- Hyaluronan in Acute Rejection and Chronic Allograft Dysfunction after Lung Transplantation - CTOT Ancillary awarded by Mount Sinai School of Medicine 2019 - 2021
- Immune Profiles to Better Understand Chronic Allograft Dysfunction and Successful Long-term Clinical Outcomes after Human Lung Transplantation awarded by National Institutes of Health 2016 - 2021
- Lung Tissue Gene Expression Profiling in Chronic Lung Allograft Dysfunction-CTOT awarded by Mount Sinai School of Medicine 2018 - 2019
- CTOT - Cell Free DNA awarded by Mount Sinai School of Medicine 2016 - 2017
- CTOT Ancillary Studies Fund Carry Forward BAL awarded by Mount Sinai School of Medicine 2016 - 2017
- Hyaluronan in Acute Rejection and Chronic Lung Allograft Dysfunction after Human Lung Transplantation awarded by Mount Sinai School of Medicine 2016 - 2017
- CTOT Ancillary Studies Fund awarded by Mount Sinai School of Medicine 2014 - 2016
- Blood-SCAN feasibility Phase 3 awarded by Harvard Pilgrim Health Care, Inc. 2013 - 2016
External Relationships
- Cellarity Inc.
- Enzyvant Therapeutics
- Natera
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Schneeberger, Pierre H. H., Chen Yang Kevin Zhang, Jessica Santilli, Bo Chen, Wei Xu, Youngho Lee, Zonelle Wijesinha, et al. “Lung Allograft Microbiome Association with Gastroesophageal Reflux, Inflammation, and Allograft Dysfunction.” Am J Respir Crit Care Med 206, no. 12 (December 15, 2022): 1495–1507. https://doi.org/10.1164/rccm.202110-2413OC.
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  - Pavlisko, Elizabeth N., Megan L. Neely, Heather Kopetskie, David M. Hwang, Carol F. Farver, W Dean Wallace, Andrea Arrossi, et al. “Prognostic implications of and clinical risk factors for acute lung injury and organizing pneumonia after lung transplantation: Data from a multicenter prospective cohort study.” Am J Transplant 22, no. 12 (December 2022): 3002–11. https://doi.org/10.1111/ajt.17183.
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  - Zhang, David, Gundula Povysil, Chad A. Newton, Toby M. Maher, Philip L. Molyneaux, Imre Noth, Fernando J. Martinez, et al. “Genome-wide Enrichment of TERT Rare Variants in Idiopathic Pulmonary Fibrosis Patients of Latino Ancestry.” Am J Respir Crit Care Med 206, no. 7 (October 1, 2022): 903–5. https://doi.org/10.1164/rccm.202203-0622LE.
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  - Shino, Michael Y., Jamie L. Todd, Megan L. Neely, Jerry Kirchner, Courtney W. Frankel, Laurie D. Snyder, Elizabeth N. Pavlisko, et al. “Plasma CXCL9 and CXCL10 at allograft injury predict chronic lung allograft dysfunction.” Am J Transplant 22, no. 9 (September 2022): 2169–79. https://doi.org/10.1111/ajt.17108.
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  - Glanville, Allan R., Christian Benden, Anne Bergeron, Guang-Shing Cheng, Jens Gottlieb, Erika D. Lease, Michael Perch, Jamie L. Todd, Kirsten M. Williams, and Geert M. Verleden. “Bronchiolitis obliterans syndrome after lung or haematopoietic stem cell transplantation: current management and future directions.” Erj Open Res 8, no. 3 (July 2022). https://doi.org/10.1183/23120541.00185-2022.
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  - Zhang, David, Gundula Povysil, Philippe H. Kobeissy, Qi Li, Binhan Wang, Mason Amelotte, Hager Jaouadi, et al. “Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis.” Am J Respir Crit Care Med 206, no. 1 (July 1, 2022): 56–69. https://doi.org/10.1164/rccm.202110-2439OC.
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  - Gao, Qimeng, Matthew G. Hartwig, and Jamie L. Todd. “Bridging the translation gap in cytomegalovirus therapeutics through ex vivo lung perfusion: Opportunities and challenges.” J Heart Lung Transplant 41, no. 3 (March 2022): 298–99. https://doi.org/10.1016/j.healun.2021.11.018.
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  - Todd, Jamie L., Megan L. Neely, Robert Overton, Hillary Mulder, Jesse Roman, Joseph A. Lasky, Joao A. de Andrade, et al. “Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort.” Lung 200, no. 1 (February 2022): 11–18. https://doi.org/10.1007/s00408-021-00505-y.
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  - Todd, Jamie L., Megan L. Neely, Robert Overton, Hillary Mulder, Jesse Roman, Joseph A. Lasky, Joao A. de Andrade, et al. “Correction to: Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort.” Lung 200, no. 1 (February 2022): 19. https://doi.org/10.1007/s00408-022-00516-3.
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  - Shino, Michael Y., Ning Li, Jamie L. Todd, Megan L. Neely, Jerry Kirchner, Heather Kopetskie, Michelle L. Sever, et al. “Correlation between BAL CXCR3 chemokines and lung allograft histopathologies: A multicenter study.” Am J Transplant 21, no. 10 (October 2021): 3401–10. https://doi.org/10.1111/ajt.16601.
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  - Wolff, Daniel, Vedran Radojcic, Robert Lafyatis, Resat Cinar, Rachel K. Rosenstein, Edward W. Cowen, Guang-Shing Cheng, et al. “National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report.” Transplant Cell Ther 27, no. 10 (October 2021): 817–35. https://doi.org/10.1016/j.jtct.2021.06.001.
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  - Hostetler, Haley P., Megan L. Neely, Francine L. Kelly, John A. Belperio, Marie Budev, John M. Reynolds, Pali D. Shah, et al. “Intragraft Hyaluronan Increases in Association With Acute Lung Transplant Rejection.” Transplant Direct 7, no. 4 (April 2021): e685. https://doi.org/10.1097/TXD.0000000000001138.
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  - Swaminathan, Aparna C., Jamie L. Todd, and Scott M. Palmer. “Advances in Human Lung Transplantation.” Annu Rev Med 72 (January 27, 2021): 135–49. https://doi.org/10.1146/annurev-med-080119-103200.
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  - Todd, J. L., and X. Luo. “Interleukin-33 Activates Regulatory T Cells to Suppress Innate γδ T-cell Responses in the Lung.” Transplantation 105, no. 1 (January 1, 2021): 10. https://doi.org/10.1097/TP.0000000000003555.
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  - Martinu, Tereza, Angela Koutsokera, Christian Benden, Edward Cantu, Daniel Chambers, Marcelo Cypel, Jeffrey Edelman, et al. “International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation.” J Heart Lung Transplant 39, no. 11 (November 2020): 1171–90. https://doi.org/10.1016/j.healun.2020.07.006.
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  - Swaminathan, Aparna C., and Jamie L. Todd. “That Was Then, This Is Now: A Fresh Look at Idiopathic Pulmonary Fibrosis Biomarkers in the Antifibrotic Era.” Chest 158, no. 4 (October 2020): 1321–22. https://doi.org/10.1016/j.chest.2020.05.564.
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  - Zhang, Chen Yang Kevin, Musawir Ahmed, Ella Huszti, Liran Levy, Sarah E. Hunter, Kristen M. Boonstra, Sajad Moshkelgosha, et al. “Bronchoalveolar bile acid and inflammatory markers to identify high-risk lung transplant recipients with reflux and microaspiration.” J Heart Lung Transplant 39, no. 9 (September 2020): 934–44. https://doi.org/10.1016/j.healun.2020.05.006.
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  - Todd, Jamie L., Megan L. Neely, Heather Kopetskie, Michelle L. Sever, Jerry Kirchner, Courtney W. Frankel, Laurie D. Snyder, et al. “Risk Factors for Acute Rejection in the First Year after Lung Transplant. A Multicenter Study.” Am J Respir Crit Care Med 202, no. 4 (August 15, 2020): 576–85. https://doi.org/10.1164/rccm.201910-1915OC.
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  - Todd, Jamie L. “Putting the 2019 CLAD consensus definitions to the test: Two steps forward, one step back?” J Heart Lung Transplant 39, no. 8 (August 2020): 771–73. https://doi.org/10.1016/j.healun.2020.06.008.
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  - Snyder, Laurie D., John Belperio, Marie Budev, Courtney Frankel, Jerry Kirchner, Tereza Martinu, Megan L. Neely, et al. “Highlights from the clinical trials in organ transplantation (CTOT)-20 and CTOT-22 Consortium studies in lung transplant.” Am J Transplant 20, no. 6 (June 2020): 1489–94. https://doi.org/10.1111/ajt.15957.
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  - O’Brien, Emily C., Anne S. Hellkamp, Megan L. Neely, Aparna Swaminathan, Shaun Bender, Laurie D. Snyder, Daniel A. Culver, et al. “Disease Severity and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis: A Cross-Sectional Analysis of the IPF-PRO Registry.” Chest 157, no. 5 (May 2020): 1188–98. https://doi.org/10.1016/j.chest.2019.11.042.
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  - Todd, Jamie L., Richard Vinisko, Yi Liu, Megan L. Neely, Robert Overton, Kevin R. Flaherty, Imre Noth, et al. “Circulating matrix metalloproteinases and tissue metalloproteinase inhibitors in patients with idiopathic pulmonary fibrosis in the multicenter IPF-PRO Registry cohort.” Bmc Pulm Med 20, no. 1 (March 14, 2020): 64. https://doi.org/10.1186/s12890-020-1103-4.
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  - Todd, Jamie L., Fran L. Kelly, Andrew Nagler, Kane Banner, Elizabeth N. Pavlisko, John A. Belperio, David Brass, S Sam Weigt, and Scott M. Palmer. “Amphiregulin contributes to airway remodeling in chronic allograft dysfunction after lung transplantation.” Am J Transplant 20, no. 3 (March 2020): 825–33. https://doi.org/10.1111/ajt.15667.
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  - Todd, Jamie L., Megan L. Neely, Robert Overton, Katey Durham, Mridu Gulati, Howard Huang, Jesse Roman, et al. “Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry.” Respir Res 20, no. 1 (October 22, 2019): 227. https://doi.org/10.1186/s12931-019-1190-z.
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  - Swaminathan, Aparna C., Megan L. Neely, Courtney W. Frankel, Fran L. Kelly, Slavé Petrovski, Michael T. Durheim, Erika Bush, et al. “Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants.” Chest 156, no. 3 (September 2019): 477–85. https://doi.org/10.1016/j.chest.2019.03.030.
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  - Todd, Jamie L., Joshua A. Hill, and Guang-Shing Cheng. “Herpesviruses: Silent Instigators of Lung Injury after Hematopoietic Cell Transplant.” Am J Respir Crit Care Med 200, no. 1 (July 1, 2019): 8–10. https://doi.org/10.1164/rccm.201901-0185ED.
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  - Kelly, Francine L., Kaitlyn E. Weinberg, Andrew E. Nagler, Andrew B. Nixon, Mark D. Star, Jamie L. Todd, David M. Brass, and Scott M. Palmer. “EGFR-Dependent IL8 Production by Airway Epithelial Cells After Exposure to the Food Flavoring Chemical 2,3-Butanedione.” Toxicol Sci 169, no. 2 (June 1, 2019): 534–42. https://doi.org/10.1093/toxsci/kfz066.
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  - Glanville, Allan R., Geert M. Verleden, Jamie L. Todd, Christian Benden, Fiorella Calabrese, Jens Gottlieb, Ramsey R. Hachem, et al. “Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome-A consensus report from the Pulmonary Council of the ISHLT.” J Heart Lung Transplant 38, no. 5 (May 2019): 483–92. https://doi.org/10.1016/j.healun.2019.03.008.
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  - Todd, Jamie L., Megan L. Neely, C. A. Finlen Copeland, Courtney W. Frankel, John M. Reynolds, and Scott M. Palmer. “Prognostic significance of early pulmonary function changes after onset of chronic lung allograft dysfunction.” J Heart Lung Transplant 38, no. 2 (February 2019): 184–93. https://doi.org/10.1016/j.healun.2018.10.006.
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  - Palmer, Scott M., Laurie Snyder, Jamie L. Todd, Benjamin Soule, Rose Christian, Kevin Anstrom, Yi Luo, Robert Gagnon, and Glenn Rosen. “Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis.” Chest 154, no. 5 (November 2018): 1061–69. https://doi.org/10.1016/j.chest.2018.08.1058.
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  - Messina, Julia A., Cameron R. Wolfe, Marion Hemmersbach-Miller, Carmelo Milano, Jamie L. Todd, John Reynolds, Barbara D. Alexander, Wiley A. Schell, Christina A. Cuomo, and John R. Perfect. “Genomic characterization of recurrent mold infections in thoracic transplant recipients.” Transpl Infect Dis 20, no. 5 (October 2018): e12935. https://doi.org/10.1111/tid.12935.
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  - Riley, Isaretta L., L Ebony Boulware, Jie-Lena Sun, Karen Chiswell, Loretta G. Que, Monica Kraft, Jamie L. Todd, Scott M. Palmer, and Monique L. Anderson. “Factors associated with reporting results for pulmonary clinical trials in ClinicalTrials.gov.” Clin Trials 15, no. 1 (February 2018): 87–94. https://doi.org/10.1177/1740774517740352.
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  - Petrovski, Slavé, Jamie L. Todd, Michael T. Durheim, Quanli Wang, Jason W. Chien, Fran L. Kelly, Courtney Frankel, et al. “An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis.” Am J Respir Crit Care Med 196, no. 1 (July 1, 2017): 82–93. https://doi.org/10.1164/rccm.201610-2088OC.
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  - Todd, Jamie L., and Scott M. Palmer. “Danger signals in regulating the immune response to solid organ transplantation.” J Clin Invest 127, no. 7 (June 30, 2017): 2464–72. https://doi.org/10.1172/JCI90594.
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  - DerHovanessian, Ariss, Jamie L. Todd, Alice Zhang, Ning Li, Aradhna Mayalall, C Ashley Finlen Copeland, Michael Shino, et al. “Validation and Refinement of Chronic Lung Allograft Dysfunction Phenotypes in Bilateral and Single Lung Recipients.” Ann Am Thorac Soc 13, no. 5 (May 2016): 627–35. https://doi.org/10.1513/AnnalsATS.201510-719OC.
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  - Genao, Liza, Michael T. Durheim, Xiaojuan Mi, Jamie L. Todd, Heather E. Whitson, and Lesley H. Curtis. “Early and Long-term Outcomes of Older Adults after Acute Care Encounters for Chronic Obstructive Pulmonary Disease Exacerbation.” Ann Am Thorac Soc 12, no. 12 (December 2015): 1805–12. https://doi.org/10.1513/AnnalsATS.201504-250OC.
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  - Verleden, S. E., J. L. Todd, M. Sato, S. M. Palmer, T. Martinu, E. N. Pavlisko, R. Vos, et al. “Impact of CLAD Phenotype on Survival After Lung Retransplantation: A Multicenter Study.” Am J Transplant 15, no. 8 (August 2015): 2223–30. https://doi.org/10.1111/ajt.13281.
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  - Sayah, David M., Beñat Mallavia, Fengchun Liu, Guadalupe Ortiz-Muñoz, Axelle Caudrillier, Ariss DerHovanessian, David J. Ross, et al. “Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation.” Am J Respir Crit Care Med 191, no. 4 (February 15, 2015): 455–63. https://doi.org/10.1164/rccm.201406-1086OC.
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  - Foster, Matthew W., Lake D. Morrison, Jamie L. Todd, Laurie D. Snyder, J Will Thompson, Erik J. Soderblom, Kelly Plonk, et al. “Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis.” J Proteome Res 14, no. 2 (February 6, 2015): 1238–49. https://doi.org/10.1021/pr501149m.
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  - Todd, J. L., and S. M. Palmer. “Alemtuzumab induction in lung transplantation: time to move on?” Am J Transplant 14, no. 8 (August 2014): 1721–22. https://doi.org/10.1111/ajt.12825.
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  - Todd, Jamie L., Jason D. Christie, and Scott M. Palmer. “Update in lung transplantation 2013.” Am J Respir Crit Care Med 190, no. 1 (July 1, 2014): 19–24. https://doi.org/10.1164/rccm.201402-0384UP.
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  - Todd, Jamie L., Xingan Wang, Seichiro Sugimoto, Vanessa E. Kennedy, Helen L. Zhang, Elizabeth N. Pavlisko, Fran L. Kelly, et al. “Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity.” Am J Respir Crit Care Med 189, no. 5 (March 1, 2014): 556–66. https://doi.org/10.1164/rccm.201308-1481OC.
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  - Todd, Jamie L., Rahil Jain, Elizabeth N. Pavlisko, C Ashley Finlen Copeland, John M. Reynolds, Laurie D. Snyder, and Scott M. Palmer. “Impact of forced vital capacity loss on survival after the onset of chronic lung allograft dysfunction.” Am J Respir Crit Care Med 189, no. 2 (January 15, 2014): 159–66. https://doi.org/10.1164/rccm.201306-1155OC.
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  - Todd, Jamie L., Kyle R. White, Karen Chiswell, Asba Tasneem, and Scott M. Palmer. “Using ClinicalTrials.gov to understand the state of clinical research in pulmonary, critical care, and sleep medicine.” Ann Am Thorac Soc 10, no. 5 (October 2013): 411–17. https://doi.org/10.1513/AnnalsATS.201305-111OC.
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  - Kennedy, V. E., J. L. Todd, and S. M. Palmer. “Bronchoalveolar lavage as a tool to predict, diagnose and understand bronchiolitis obliterans syndrome.” Am J Transplant 13, no. 3 (March 2013): 552–61. https://doi.org/10.1111/ajt.12091.
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  - Bedoya, A. D., J. L. Todd, T. Martinu, S. M. Palmer, and L. D. Snyder. “Lung Transplantation For Pulmonary Complications After Bone Marrow Transplantation.” American Journal of Respiratory and Critical Care Medicine 187 (January 1, 2013).
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  - Davis, W. A., C. A. Finlen Copeland, J. L. Todd, L. D. Snyder, J. A. Martissa, and S. M. Palmer. “Spirometrically significant acute rejection increases the risk for BOS and death after lung transplantation.” Am J Transplant 12, no. 3 (March 2012): 745–52. https://doi.org/10.1111/j.1600-6143.2011.03849.x.
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  - Todd, Jamie L., and Scott M. Palmer. “Montelukast for Bronchiolitis Obliterans Syndrome After Lung Transplantation: Response.” Chest 141, no. 1 (January 2012): 276. https://doi.org/10.1378/chest.11-2258.
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  - Todd, Jamie L., David B. Goldstein, Dongliang Ge, Jason Christie, and Scott M. Palmer. “The state of genome-wide association studies in pulmonary disease: a new perspective.” Am J Respir Crit Care Med 184, no. 8 (October 15, 2011): 873–80. https://doi.org/10.1164/rccm.201106-0971PP.
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  - Todd, Jamie L., and Scott M. Palmer. “Bronchiolitis obliterans syndrome: the final frontier for lung transplantation.” Chest 140, no. 2 (August 2011): 502–8. https://doi.org/10.1378/chest.10-2838.
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  - Todd, Jamie L., and Scott M. Palmer. “Lung transplantation in advanced COPD: is it worth it?” Semin Respir Crit Care Med 31, no. 3 (June 2010): 365–72. https://doi.org/10.1055/s-0030-1254076.
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  - Todd, Jamie L., and Victor F. Tapson. “Thrombolytic therapy for acute pulmonary embolism: a critical appraisal.” Chest 135, no. 5 (May 2009): 1321–29. https://doi.org/10.1378/chest.08-2125.
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  - Mwita, W., J. Chilongani, R. White, G. Mshana, J. Changalucha, F. Mosha, D. Ross, B. Zaba, and J. Todd. “Has the HIV epidemic in rural Mwanza, Tanzania reached a plateau?” Tanzan J Health Res 10, no. 3 (July 2008): 117–23. https://doi.org/10.4314/thrb.v10i3.14333.
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  - Todd, J. L., J. Lakey, D. Howell, M. Reidy, and D. Zaas. “Portal hypertension and granulomatous liver disease in a lung transplant recipient due to disseminated atypical mycobacterial infection.” Am J Transplant 7, no. 5 (May 2007): 1300–1303. https://doi.org/10.1111/j.1600-6143.2007.01748.x.
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  - Ross, S. E., J. Todd, L. A. Moore, B. L. Beaty, L. Wittevrongel, and C. T. Lin. “Expectations of patients and physicians regarding patient-accessible medical records.” Journal of Medical Internet Research 7, no. 2 (January 1, 2005). https://doi.org/10.2196/jmir.7.2.e13.
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- Book Sections
  - Smith, J. B., and J. L. Todd. “Chronic Lung Allograft Dysfunction.” In Encyclopedia of Respiratory Medicine, Second Edition, 5:741–56, 2021. https://doi.org/10.1016/B978-0-08-102723-3.00173-6.
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  - Todd, J. L., and S. M. Palmer. “Innate immune responses and bronchiolitis obliterans syndrome.” In Bronchiolitis Obliterans Syndrome in Lung Transplantation, 147–67, 2013. https://doi.org/10.1007/978-1-4614-7636-8_8.
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- Conference Papers
  - Hostetler, Haley P., Megan L. Neely, Elizabeth Lydon, Lara A. Danziger-Isakov, Jamie L. Todd, and Scott M. Palmer. “Immunity to varicella, measles, and mumps in patients evaluated for lung transplantation.” In Am J Transplant, 21:2864–70, 2021. https://doi.org/10.1111/ajt.16602.
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  - Levy, L., M. Ahmed, E. Huszti, C. K. Zhang, S. E. Hunter, K. M. Boonstra, A. T. Sage, et al. “Bronchoalveolar Bile Acids are Associated with Acute Rejection, Inflammation, and Allograft Survival: A Multi-Center Study.” In Journal of Heart and Lung Transplantation, 40:S62–63, 2021.
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  - Luckhardt, T., M. L. Neely, H. Mulder, J. A. Belperio, M. Ramaswamy, M. L. Salisbury, C. Hesslinger, S. M. Palmer, J. L. Todd, and T. B. Leonard. “Associations Between Circulating MicroRNAs and Clinical Outcomes in Patients with IPF: Data from the IPF-PRO Registry.” In American Journal of Respiratory and Critical Care Medicine, Vol. 203, 2021.
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  - Schneeberger, P. H., C. Zhang, J. Santilli, Z. Wijesinha, L. Levy, B. Chen, W. Xu, et al. “The Pulmonary Microbiome after Lung Transplantation is Associated with Gastroesophageal Reflux Disease, Inflammation, and Allograft Dysfunction.” In Journal of Heart and Lung Transplantation, 40:S59–60, 2021.
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  - Liu, Yi, Huang Lin, Julia F. Soellner, Janine Roy, Richard Vinisko, Ramona Schmid, Benjamin Strobel, et al. “Integrative clustering analysis to discover novel IPF disease subtypes in the IPF-PRO Registry.” In Idiopathic Interstitial Pneumonias. European Respiratory Society, 2020. https://doi.org/10.1183/13993003.congress-2020.733.
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  - Oldham, Justin, Jamie L. Todd, Megan L. Neely, Hillary Mulder, Robert Overton, Hyun J. Kim, Mridu Gulati, et al. “Association of neoepitopes with disease severity and respiratory hospitalization in patients with IPF.” In Idiopathic Interstitial Pneumonias. European Respiratory Society, 2020. https://doi.org/10.1183/13993003.congress-2020.5188.
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  - Frankel, C. W., H. Kopetskie, M. Sever, M. Cosgrove, J. Kirchner, M. Robien, N. Williams, et al. “Prospective Assessment of Chronic Lung Allograft Dysfunction (CLAD); the Clinical Trials in Organ Transplantation (CTOT) Study Experience.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S303, 2020. https://doi.org/10.1016/j.healun.2020.01.677.
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  - Rozenberg, D., L. G. Singer, M. L. Neely, J. M. Weber, H. A. Kopetskie, M. L. Sever, J. Kirchner, et al. “Agreement between Fried Frailty Phenotype and Cumulative Deficits Frailty Indices: A Prospective Multi-Center Study.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S314, 2020. https://doi.org/10.1016/j.healun.2020.01.707.
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  - Shino, M. Y., R. M. Elashoff, N. Li, J. L. Todd, M. L. Neely, H. Kopetskie, M. Sever, et al. “A Multi-Center Study of BAL CXCR3 Chemokines during Allograft Injury after Lung Transplantation.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S115, 2020. https://doi.org/10.1016/j.healun.2020.01.990.
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  - Todd, J. L., F. L. Kelly, M. L. Neely, K. Keslar, E. N. Pavlisko, S. J. McCall, A. Fletcher, et al. “NanoString Gene Expression Profiling in Chronic Lung Allograft Dysfunction (CLAD).” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S113, 2020. https://doi.org/10.1016/j.healun.2020.01.985.
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  - Zhang, C., P. H. Schneeberger, L. Levy, Y. Lee, E. Huszti, S. E. Hunter, M. Ahmed, et al. “Pulmonary Microbiome Changes in Lung Transplant Recipients with Gastroesophageal Reflux.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S105, 2020. https://doi.org/10.1016/j.healun.2020.01.963.
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  - Noth, I., J. Roy, R. Schmid, R. Vinisko, B. Strobel, M. L. Neely, C. Hesslinger, et al. “Relationship Between MRNA-microRNA Interactions and Forced Vital Capacity in Patients with Idiopathic Pulmonary Fibrosis.” In American Journal of Respiratory and Critical Care Medicine, Vol. 201, 2020.
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  - Palmer, S. M., M. L. Neely, J. A. Belperio, S. Bender, D. A. Culver, J. De Andrade, E. C. O’Brien, et al. “Improving Our Understanding of Progressive Fibrosing Interstitial Lung Diseases (ILDs): Design of the ILD-PRO Registry.” In American Journal of Respiratory and Critical Care Medicine, Vol. 201, 2020.
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  - Swaminathan, A. C., J. Li, K. Chiswell, W. McManigle, I. O’Doherty, W. Fitzsimmons, J. L. Todd, S. Tibbs, and S. M. Palmer. “The State of Interventional Clinical Trials in Solid Organ Transplant: Insights from a Systematic Analysis of Clinicaltrials.gov.” In American Journal of Transplantation, 20:598–598, 2020.
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  - Swaminathan, A., R. Clare, W. McManigle, K. Chiswell, M. Robertshaw, J. Cu, M. Dorry, S. Tibbs, J. L. Todd, and S. M. Palmer. “The State of Interventional Clinical Research in Pulmonary, Critical Care, and Sleep Medicine: Insights from a Systematic Analysis of Clinicaltrials.gov.” In American Journal of Respiratory and Critical Care Medicine, Vol. 201, 2020.
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  - Todd, J. L., M. L. Neely, R. Overton, H. Mulder, J. Roman, J. A. Lasky, J. De Andrade, et al. “Association of Circulating Proteins with Death or Lung Transplant in the IPF-PRO Registry Cohort.” In American Journal of Respiratory and Critical Care Medicine, Vol. 201, 2020.
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  - Hesslinger, Christian, Robert Overton, Sascha Keller, Megan L. Neely, John A. Belperio, Richard Vinisko, Thomas Leonard, et al. “The circulating metabolome in idiopathic pulmonary fibrosis (IPF).” In European Respiratory Journal, Vol. 54. EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2019. https://doi.org/10.1183/13993003.congress-2019.0A1924.
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  - Ahmed, M., L. Levy, S. E. Hunter, K. C. Zhang, E. Huszti, K. M. Boonstra, A. T. Sage, et al. “Lung Bile Acid as Biomarker of Microaspiration and Its Relationship to Lung Inflammation.” In The Journal of Heart and Lung Transplantation, 38:S255–56. Elsevier BV, 2019. https://doi.org/10.1016/j.healun.2019.01.635.
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  - Martinu, T., A. Koutsokera, C. Benden, E. Cantu, D. Chambers, M. Cypel, J. Edelman, et al. “ISHLT Consensus on Standardization of Bronchoalveolar Lavage in Lung Transplantation.” In The Journal of Heart and Lung Transplantation, 38:S120–21. Elsevier BV, 2019. https://doi.org/10.1016/j.healun.2019.01.283.
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  - Pavlisko, E. N., M. L. Neely, H. Kopetskie, D. Hwang, C. F. Farver, A. V. Arrossi, W. D. Wallace, et al. “Occurrence and Risk Factors for Acute Lung Injury (ALI) and Organizing Pneumonia (OP) after Lung Transplant.” In The Journal of Heart and Lung Transplantation, 38:S56–57. Elsevier BV, 2019. https://doi.org/10.1016/j.healun.2019.01.124.
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  - Todd, J. L., M. L. Neely, H. Kopetskie, M. Sever, J. Kirchner, C. W. Frankel, L. D. Snyder, et al. “Acute Rejection (AR) and Lymphocytic Bronchiolitis (LB) in a Multicenter Lung Transplant Cohort.” In The Journal of Heart and Lung Transplantation, 38:S402–3. Elsevier BV, 2019. https://doi.org/10.1016/j.healun.2019.01.1025.
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  - Zhang, K. C., S. E. Hunter, E. Huszti, M. Ahmed, L. Levy, K. M. Boonstra, A. T. Sage, et al. “Effects of Nissen Fundoplication on Markers of Microaspiration and Inflammation after Lung Transplantation.” In The Journal of Heart and Lung Transplantation, 38:S73–74. Elsevier BV, 2019. https://doi.org/10.1016/j.healun.2019.01.166.
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  - Todd, J. L., K. Durham, R. Overton, M. Neely, J. A. Belperio, M. Gulati, H. J. Huang, et al. “Peripheral Blood Proteomic Profiling to Distinguish Disease Biomarkers in the Multicenter IPF-PRO Registry Cohort.” In American Journal of Respiratory and Critical Care Medicine, Vol. 199. AMER THORACIC SOC, 2019.
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  - Todd, J. L., M. L. Neely, R. Overton, M. Gulati, H. J. Huang, J. Roman, K. R. Flaherty, et al. “Association of Circulating Proteins with Disease Specific Measures in the Multicenter IPF-PRO Registry Cohort.” In American Journal of Respiratory and Critical Care Medicine, Vol. 199. AMER THORACIC SOC, 2019.
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  - Noth, I., R. Schmid, B. Strobel, G. Leparc, J. Roy, R. Vinisko, M. Neely, et al. “Peripheral Blood Gene Expression Profiling in the Multicenter IPF-PRO Registry Cohort.” In American Journal of Respiratory and Critical Care Medicine, Vol. 199. AMER THORACIC SOC, 2019.
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  - Todd, J. L., M. L. Neely, C. Brinkley, F. L. Kelly, C. W. Frankel, J. Kirchner, J. A. Belperio, et al. “Hyaluronan in Acute Rejection After Lung Transplantation.” In The Journal of Heart and Lung Transplantation, 37:S441–S441. Elsevier BV, 2018. https://doi.org/10.1016/j.healun.2018.01.1144.
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  - Todd, J. L., V. Venkat, R. Henao, C. Brinkley, F. L. Kelly, C. W. Frankel, A. Frear, et al. “Bronchoalveolar Lavage Fluid Proteome in Chronic Lung Allograft Dysfunction.” In The Journal of Heart and Lung Transplantation, 37:S204–S204. Elsevier BV, 2018. https://doi.org/10.1016/j.healun.2018.01.496.
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  - Fuller, Candace C., Craig Zinderman, Steven A. Anderson, Carolyn Balsbaugh, Nicholas Bryant, Hayley Burgess, Howard Chazin, et al. “Assessment of Transfusion-Related Acute Lung Injury after Red Blood Cell, Plasma and Platelet Administration: Initial Results in the Sentinel System.” In Pharmacoepidemiology and Drug Safety, 26:385–385. WILEY, 2017.
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  - Klement, W., J. Tikkanen, S. Juvet, J. L. Todd, S. S. Weigt, L. D. Snyder, S. Azad, et al. “Automating the Diagnosis of Potential CLAD and Its Subtypes in Lung Transplant Recipients.” In Journal of Heart and Lung Transplantation, 36:S309–S309. ELSEVIER SCIENCE INC, 2017.
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  - Todd, J. L., A. J. Mikels-Vigdal, F. L. Kelly, E. N. Pavlisko, I. Mikaelian, T. G. O’Riordan, V. C. Smith, and S. M. Palmer. “Loxl-2 Contributes To The Development Of Obliterative Bronchiolitis (ob) In Humans.” In American Journal of Respiratory and Critical Care Medicine, Vol. 195. AMER THORACIC SOC, 2017.
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  - Todd, J. L., M. W. Foster, A. Valente, C. Brinkley, H. A. Ali, J. M. Reynolds, F. L. Kelly, and S. M. Palmer. “Proteomics Of Bronchoalveolar Lavage (bal) Fluid In Bronchiolitis Obliterans Syndrome (bos).” In American Journal of Respiratory and Critical Care Medicine, Vol. 195. AMER THORACIC SOC, 2017.
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  - Durheim, M. T., D. M. Wojdyla, C. L. Green, S. Keshavjee, K. McCurry, A. O. Lidor, R. D. Davis, S. M. Palmer, and J. L. Todd. “Evaluation of an FVC-Based Definition of Restrictive Chronic Lung Allograft Dysfunction (CLAD) in a Multi-Center Cohort.” In The Journal of Heart and Lung Transplantation, 35:S117–18. Elsevier BV, 2016. https://doi.org/10.1016/j.healun.2016.01.321.
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  - Todd, J. L., C. A. Finlen Copeland, M. Neely, and S. M. Palmer. “FVC and FEV1 Decline in Chronic Lung Allograft Dysfunction (CLAD) Phenotypes.” In The Journal of Heart and Lung Transplantation, 35:S223–24. Elsevier BV, 2016. https://doi.org/10.1016/j.healun.2016.01.633.
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  - O’Brien, E. C., P. Shrader, M. T. Durheim, L. D. Snyder, J. L. Todd, V. Gamerman, K. J. Anstrom, et al. “Disease Severity And Quality Of Life In Newly Diagnosed Idiopathic Pulmonary Fibrosis Patients.” In American Journal of Respiratory and Critical Care Medicine, Vol. 193. AMER THORACIC SOC, 2016.
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  - Ali, H. A., L. D. Snyder, L. F. Diehl, J. L. Todd, and S. Aryal. “Atypical Primary Effusion Lymphoma In A Lung Transplant Recipient.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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  - Aryal, S., E. N. Pavlisko, and J. L. Todd. “A Case Of Acute Fibrinous And Organizing Pneumonia Associated With Development Of Anti-Hla Antibodies After Lung Transplantation.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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  - Chery, G. S., S. M. Palmer, L. D. Snyder, A. L. Gray, J. L. Todd, G. Harrison, and E. N. Pavlisko. “Post-Transplant Lymphoproliferative Disorder Erosion Into A Large Pulmonary Artery With Death Secondary To Hemorrhagic Shock.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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  - Chery, G. S., S. M. Palmer, L. D. Snyder, J. L. Todd, and C. Wolfe. “Brincidofovir In Progressive Multifocal Leukoencephalopathy After Lung Transplant.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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  - Copeland, CA Finlen, J. A. Martissa, C. W. Frankel, E. C. Benedetti, E. Callahan, D. Ross, S. M. Palmer, et al. “A Prospective Multicenter Assessment Of Aztreonam Lysine For Inhalation In The Treatment Of Lung Transplant Recipients With Chronic Lung Allograft Dysfunction.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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  - Todd, J. L., F. L. Kelly, D. M. Brass, V. E. Kennedy, E. N. Pavlisko, and S. M. Palmer. “Increased Amphiregulin Expression Is Associated With Chronic Allograft Dysfunction After Lung Transplantation.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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  - Todd, J. L., T. J. Urban, C. A. Finlen Copeland, F. L. Kelly, D. B. Goldstein, and S. M. Palmer. “Whole Exome Sequencing: A Novel Strategy to Understand Chronic Lung Allograft Dysfunction (CLAD).” In The Journal of Heart and Lung Transplantation, 33:S140–S140. Elsevier BV, 2014. https://doi.org/10.1016/j.healun.2014.01.377.
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  - Todd, J. L., V. E. Kennedy, E. N. Pavlisko, H. L. Zhang, F. L. Kelly, and S. M. Palmer. “Elevated Hyaluronan Is Associated with Bronchiolitis Obliterans Syndrome.” In The Journal of Heart and Lung Transplantation, 33:S106–7. Elsevier BV, 2014. https://doi.org/10.1016/j.healun.2014.01.319.
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  - Todd, J. L., R. Jain, E. N. Pavlisko, C Finlen Copeland, L. D. Snyder, and S. M. Palmer. “Restrictive Spirometry At Bronchiolitis Obliterans Syndrome Onset Predicts Worse Survival.” In American Journal of Respiratory and Critical Care Medicine, Vol. 187. AMER THORACIC SOC, 2013.
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