Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Pulmonary Medicine, Medicine, Duke University 2008 - 2009
  • Resident, Medicine, Duke University 2005 - 2008
  • M.D., University of Colorado School of Medicine 2005
• 

  Duke Appointment History

  • Medical Instructor in the Department of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2012 - 2015
  • Medical Instructor in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2009 - 2010
• Research
• 

  Selected Grants

  • Immune Profiles to Better Understand Chronic Allograft Dysfunction and Successful Long-term Clinical Outcomes after Human Lung Transplantation awarded by National Institutes of Health 2016 - 2021
  • Genetics of Acute Rejection and Chronic Lung Allograft Dysfunction awarded by Cystic Fibrosis Foundation 2019 - 2020
  • Lung Tissue Gene Expression Profiling in Chronic Lung Allograft Dysfunction-CTOT awarded by Mount Sinai School of Medicine 2018 - 2019
  • CTOT - Cell Free DNA awarded by Mount Sinai School of Medicine 2016 - 2017
  • CTOT Ancillary Studies Fund Carry Forward BAL awarded by Mount Sinai School of Medicine 2016 - 2017
  • Hyaluronan in Acute Rejection and Chronic Lung Allograft Dysfunction after Human Lung Transplantation awarded by Mount Sinai School of Medicine 2016 - 2017
  • CTOT Ancillary Studies Fund awarded by Mount Sinai School of Medicine 2014 - 2016
  • Blood-SCAN feasibility Phase 3 awarded by Harvard Pilgrim Health Care, Inc. 2013 - 2016
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Glanville, AR, Verleden, GM, Todd, JL, Benden, C, Calabrese, F, Gottlieb, J, Hachem, RR, Levine, D, Meloni, F, Palmer, SM, Roman, A, Sato, M, Singer, LG, Tokman, S, Verleden, SE, von der Thüsen, J, Vos, R, and Snell, G. "Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome-A consensus report from the Pulmonary Council of the ISHLT." The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation 38, no. 5 (May 2019): 483-492.  Full Text
    • Kelly, FL, Weinberg, KE, Nagler, AE, Nixon, AB, Star, MD, Todd, JL, Brass, DM, and Palmer, SM. "EGFR-dependent IL8 Production by Airway Epithelial Cells after Exposure to the Food Flavoring Chemical 2,3-butanedione." Toxicological Sciences : an Official Journal of the Society of Toxicology (March 9, 2019).  Full Text
    • Todd, JL, Hill, JA, and Cheng, G-S. "Herpesviruses: Silent Instigators of Lung Injury after Hematopoietic Cell Transplant." American Journal of Respiratory and Critical Care Medicine (February 20, 2019).  Full Text
    • Todd, JL, Neely, ML, Finlen Copeland, CA, Frankel, CW, Reynolds, JM, and Palmer, SM. "Prognostic significance of early pulmonary function changes after onset of chronic lung allograft dysfunction." The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation 38, no. 2 (February 2019): 184-193.  Full Text
    • Palmer, SM, Snyder, L, Todd, JL, Soule, B, Christian, R, Anstrom, K, Luo, Y, Gagnon, R, and Rosen, G. "Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis." Chest 154, no. 5 (November 2018): 1061-1069.  Full Text
    • Messina, JA, Wolfe, CR, Hemmersbach-Miller, M, Milano, C, Todd, JL, Reynolds, J, Alexander, BD, Schell, WA, Cuomo, CA, and Perfect, JR. "Genomic characterization of recurrent mold infections in thoracic transplant recipients." Transplant Infectious Disease : an Official Journal of the Transplantation Society 20, no. 5 (October 2018): e12935-null.  Full Text
    • Riley, IL, Boulware, LE, Sun, J-L, Chiswell, K, Que, LG, Kraft, M, Todd, JL, Palmer, SM, and Anderson, ML. "Factors associated with reporting results for pulmonary clinical trials in ClinicalTrials.gov." Clinical Trials (London, England) 15, no. 1 (February 2018): 87-94.  Full Text
    • Petrovski, S, Todd, JL, Durheim, MT, Wang, Q, Chien, JW, Kelly, FL, Frankel, C, Mebane, CM, Ren, Z, Bridgers, J, Urban, TJ, Malone, CD, Finlen Copeland, A, Brinkley, C, Allen, AS, O'Riordan, T, McHutchison, JG, Palmer, SM, and Goldstein, DB. "An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis." American Journal of Respiratory and Critical Care Medicine 196, no. 1 (July 2017): 82-93.  Full Text
    • Todd, JL, and Palmer, SM. "Danger signals in regulating the immune response to solid organ transplantation." The Journal of Clinical Investigation 127, no. 7 (June 2017): 2464-2472. (Review)  Full Text
    • DerHovanessian, A, Todd, JL, Zhang, A, Li, N, Mayalall, A, Finlen Copeland, CA, Shino, M, Pavlisko, EN, Wallace, WD, Gregson, A, Ross, DJ, Saggar, R, Lynch, JP, Belperio, J, Snyder, LD, Palmer, SM, and Weigt, SS. "Validation and Refinement of Chronic Lung Allograft Dysfunction Phenotypes in Bilateral and Single Lung Recipients." Annals of the American Thoracic Society 13, no. 5 (May 2016): 627-635.  Full Text
    • Genao, L, Durheim, MT, Mi, X, Todd, JL, Whitson, HE, and Curtis, LH. "Early and Long-term Outcomes of Older Adults after Acute Care Encounters for Chronic Obstructive Pulmonary Disease Exacerbation." Annals of the American Thoracic Society 12, no. 12 (December 2015): 1805-1812.  Full Text
    • Verleden, SE, Todd, JL, Sato, M, Palmer, SM, Martinu, T, Pavlisko, EN, Vos, R, Neyrinck, A, Van Raemdonck, D, Saito, T, Oishi, H, Keshavjee, S, Greer, M, Warnecke, G, Gottlieb, J, and Haverich, A. "Impact of CLAD Phenotype on Survival After Lung Retransplantation: A Multicenter Study." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, no. 8 (August 2015): 2223-2230.  Full Text
    • Foster, MW, Morrison, LD, Todd, JL, Snyder, LD, Thompson, JW, Soderblom, EJ, Plonk, K, Weinhold, KJ, Townsend, R, Minnich, A, and Moseley, MA. "Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis." Journal of Proteome Research 14, no. 2 (February 2015): 1238-1249.  Full Text
    • Sayah, DM, Mallavia, B, Liu, F, Ortiz-Muñoz, G, Caudrillier, A, DerHovanessian, A, Ross, DJ, Lynch, JP, Saggar, R, Ardehali, A, Lung Transplant Outcomes Group Investigators, , Ware, LB, Christie, JD, Belperio, JA, and Looney, MR. "Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation." American Journal of Respiratory and Critical Care Medicine 191, no. 4 (February 2015): 455-463.  Full Text
    • Todd, JL, and Palmer, SM. "Alemtuzumab induction in lung transplantation: time to move on?." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 14, no. 8 (August 2014): 1721-1722.  Full Text
    • Todd, JL, Christie, JD, and Palmer, SM. "Update in lung transplantation 2013." American Journal of Respiratory and Critical Care Medicine 190, no. 1 (July 2014): 19-24.  Full Text
    • Todd, JL, Wang, X, Sugimoto, S, Kennedy, VE, Zhang, HL, Pavlisko, EN, Kelly, FL, Huang, H, Kreisel, D, Palmer, SM, and Gelman, AE. "Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity." American Journal of Respiratory and Critical Care Medicine 189, no. 5 (March 2014): 556-566.  Full Text
    • Todd, JL, Jain, R, Pavlisko, EN, Finlen Copeland, CA, Reynolds, JM, Snyder, LD, and Palmer, SM. "Impact of forced vital capacity loss on survival after the onset of chronic lung allograft dysfunction." Am J Respir Crit Care Med 189, no. 2 (January 15, 2014): 159-166.  Full Text  Link to Item
    • Todd, JL, and Palmer, SM. "Alemtuzumab induction in lung transplantation: Time to move on?." American Journal of Transplantation 14, no. 8 (January 1, 2014): 1721-1722.  Full Text
    • Todd, JL, White, KR, Chiswell, K, Tasneem, A, and Palmer, SM. "Using ClinicalTrials.gov to understand the state of clinical research in pulmonary, critical care, and sleep medicine." Annals of the American Thoracic Society 10, no. 5 (October 2013): 411-417.  Full Text
    • Kennedy, VE, Todd, JL, and Palmer, SM. "Bronchoalveolar lavage as a tool to predict, diagnose and understand bronchiolitis obliterans syndrome." Am J Transplant 13, no. 3 (March 2013): 552-561. (Review)  Full Text  Link to Item
    • Bedoya, AD, Todd, JL, Martinu, T, Palmer, SM, and Snyder, LD. "Lung Transplantation For Pulmonary Complications After Bone Marrow Transplantation." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 187 (2013).  Link to Item
    • Davis, WA, Finlen Copeland, CA, Todd, JL, Snyder, LD, Martissa, JA, and Palmer, SM. "Spirometrically significant acute rejection increases the risk for BOS and death after lung transplantation." Am J Transplant 12, no. 3 (March 2012): 745-752.  Full Text  Link to Item
    • Todd, JL, and Palmer, SM. "Response." Chest 141, no. 1 (January 1, 2012): 276-null. (Letter)  Full Text
    • Todd, JL, Goldstein, DB, Ge, D, Christie, J, and Palmer, SM. "The state of genome-wide association studies in pulmonary disease: a new perspective." American Journal of Respiratory and Critical Care Medicine 184, no. 8 (October 2011): 873-880. (Review)  Full Text
    • Todd, JL, and Palmer, SM. "Bronchiolitis obliterans syndrome: the final frontier for lung transplantation." Chest 140, no. 2 (August 2011): 502-508. (Review)  Full Text
    • Todd, JL, and Palmer, SM. "Lung transplantation in advanced COPD: is it worth it?." Semin Respir Crit Care Med 31, no. 3 (June 2010): 365-372. (Review)  Full Text  Link to Item
    • Todd, JL, and Tapson, VF. "Thrombolytic therapy for acute pulmonary embolism: a critical appraisal." Chest 135, no. 5 (May 2009): 1321-1329. (Review)  Full Text
    • Mwita, W, Chilongani, J, White, R, Mshana, G, Changalucha, J, Mosha, F, Ross, D, Zaba, B, and Todd, J. "Has the HIV epidemic in rural Mwanza, Tanzania reached a plateau?." Tanzania Journal of Health Research 10, no. 3 (July 2008): 117-123.
    • Todd, JL, Lakey, J, Howell, D, Reidy, M, and Zaas, D. "Portal hypertension and granulomatous liver disease in a lung transplant recipient due to disseminated atypical mycobacterial infection." Am J Transplant 7, no. 5 (May 2007): 1300-1303.  Full Text  Link to Item
    • Ross, SE, Todd, J, Moore, LA, Beaty, BL, Wittevrongel, L, and Lin, CT. "Expectations of patients and physicians regarding patient-accessible medical records." Journal of Medical Internet Research 7, no. 2 (April 1, 2005). (Review)  Full Text

  • Book Sections

    • Todd, JL, and Palmer, SM. "Innate immune responses and bronchiolitis obliterans syndrome." In Bronchiolitis Obliterans Syndrome in Lung Transplantation, 147-167. January 1, 2013.  Full Text

  • Conference Papers

    • Swaminathan, AC, Neely, ML, Frankel, CW, Kelly, FL, Petrovski, S, Durheim, MT, Bush, E, Snyder, L, Goldstein, DB, Todd, JL, and Palmer, SM. "Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants." April 9, 2019.  Full Text
    • Ahmed, M, Levy, L, Hunter, SE, Zhang, KC, Huszti, E, Boonstra, KM, Sage, AT, Azad, S, Zamel, R, Ghany, R, Yeung, JC, Crespin, OM, Frankel, C, Budev, M, Shah, P, Snyder, LD, Belperio, J, Singer, LG, Weigt, SS, Todd, JL, Palmer, SM, Keshavjee, S, and Martinu, T. "Lung Bile Acid as Biomarker of Microaspiration and Its Relationship to Lung Inflammation." : Elsevier BV, April 2019.  Full Text
    • Martinu, T, Koutsokera, A, Benden, C, Cantu, E, Chambers, D, Cypel, M, Edelman, J, Emtiazjoo, A, Fisher, AJ, Greenland, JR, Hayes, D, Hwang, DM, Keller, BC, Lease, ED, Perch, M, Sato, M, Todd, JL, Verleden, S, von der Thüsen, J, Weigt, SS, and Keshavjee, S. "ISHLT Consensus on Standardization of Bronchoalveolar Lavage in Lung Transplantation." : Elsevier BV, April 2019.  Full Text
    • Pavlisko, EN, Neely, ML, Kopetskie, H, Hwang, D, Farver, CF, Arrossi, AV, Wallace, WD, Illei, P, Sever, M, Kirchner, J, Frankel, CW, Snyder, LD, Martinu, T, Shino, MY, Williams, N, Robien, MA, Singer, LG, Budev, M, Tsuang, W, Shah, PD, Reynolds, JM, Weigt, S, Belperio, JA, Palmer, SM, and Todd, JL. "Occurrence and Risk Factors for Acute Lung Injury (ALI) and Organizing Pneumonia (OP) after Lung Transplant." : Elsevier BV, April 2019.  Full Text
    • Todd, JL, Neely, ML, Kopetskie, H, Sever, M, Kirchner, J, Frankel, CW, Snyder, LD, Pavlisko, EN, Martinu, T, Tsuang, W, Shino, M, Williams, N, Robien, MA, Singer, LG, Budev, M, Shah, PD, Reynolds, JM, Palmer, SM, Belperio, JA, and Weigt, SS. "Acute Rejection (AR) and Lymphocytic Bronchiolitis (LB) in a Multicenter Lung Transplant Cohort." : Elsevier BV, April 2019.  Full Text
    • Zhang, KC, Hunter, SE, Huszti, E, Ahmed, M, Levy, L, Boonstra, KM, Sage, AT, Azad, S, Zamel, R, Frankel, C, Budev, M, Shah, P, Snyder, LD, Belperio, J, Singer, LG, Weigt, SS, Todd, JL, Keshavjee, S, Palmer, SM, and Martinu, T. "Effects of Nissen Fundoplication on Markers of Microaspiration and Inflammation after Lung Transplantation." : Elsevier BV, April 2019.  Full Text
    • Todd, JL, Neely, ML, Brinkley, C, Kelly, FL, Frankel, CW, Kirchner, J, Belperio, JA, Budev, M, Shah, PD, Singer, LG, Reynolds, JM, and Palmer, SM. "Hyaluronan in Acute Rejection After Lung Transplantation." 38th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT). Nice, FRANCE. April 11, 2018 - April 14, 2018.: ELSEVIER SCIENCE INC, April 1, 2018.  Link to Item
    • Todd, JL, Venkat, V, Henao, R, Brinkley, C, Kelly, FL, Frankel, CW, Frear, A, Moseley, MA, Thompson, JW, Belperio, JA, Budev, M, Shah, PD, Singer, LG, Reynolds, JM, Foster, MW, and Palmer, SM. "Bronchoalveolar Lavage Fluid Proteome in Chronic Lung Allograft Dysfunction." 38th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT). Nice, FRANCE. April 11, 2018 - April 14, 2018.: ELSEVIER SCIENCE INC, April 1, 2018.  Link to Item
    • Fuller, CC, Zinderman, C, Anderson, SA, Balsbaugh, C, Bryant, N, Burgess, H, Chazin, H, Clark, P, Curtis, LH, Forshee, R, Hickok, J, Honda, S, Kaufman, RM, Menis, M, Miller, KM, Niu, M, Obidi, J, Paul, W, Poland, R, Rosofsky, R, Shoaibi, A, Spencer-Smith, C, Todd, JL, Zhang, F, and Baker, MA. "Assessment of Transfusion-Related Acute Lung Injury after Red Blood Cell, Plasma and Platelet Administration: Initial Results in the Sentinel System." : WILEY, August 1, 2017.  Link to Item
    • Klement, W, Tikkanen, J, Juvet, S, Todd, JL, Weigt, SS, Snyder, LD, Azad, S, Belperio, JA, Palmer, SM, Singer, LG, Keshavjee, S, and Martinu, T. "Automating the Diagnosis of Potential CLAD and Its Subtypes in Lung Transplant Recipients." April 2017.  Link to Item
    • Todd, JL, Foster, MW, Valente, A, Brinkley, C, Ali, HA, Reynolds, JM, Kelly, FL, and Palmer, SM. "Proteomics Of Bronchoalveolar Lavage (bal) Fluid In Bronchiolitis Obliterans Syndrome (bos)." 2017.  Link to Item
    • Todd, JL, Mikels-Vigdal, AJ, Kelly, FL, Pavlisko, EN, Mikaelian, I, O'Riordan, TG, Smith, VC, and Palmer, SM. "Loxl-2 Contributes To The Development Of Obliterative Bronchiolitis (ob) In Humans." 2017.  Link to Item
    • Durheim, M, Wojdyla, D, Green, C, Keshavjee, S, McCurry, K, Lidor, A, Davis, R, Palmer, S, and Todd, J. "Evaluation of an FVC-Based Definition of Restrictive Chronic Lung Allograft Dysfunction (CLAD) in a Multi-Center Cohort." April 2016.  Full Text
    • Todd, J, Finlen Copeland, C, Neely, M, and Palmer, S. "FVC and FEV1 Decline in Chronic Lung Allograft Dysfunction (CLAD) Phenotypes." April 2016.  Full Text
    • O'Brien, EC, Shrader, P, Durheim, MT, Snyder, LD, Todd, JL, Gamerman, V, Anstrom, KJ, Belperio, JA, Culver, DA, De Andrade, JAM, Roman, J, Whelan, TPM, Conoscenti, CS, and Palmer, SM. "Disease Severity And Quality Of Life In Newly Diagnosed Idiopathic Pulmonary Fibrosis Patients." 2016.  Link to Item
    • Ali, HA, Snyder, LD, Diehl, LF, Todd, JL, and Aryal, S. "Atypical Primary Effusion Lymphoma In A Lung Transplant Recipient." 2015.  Link to Item
    • Aryal, S, Pavlisko, EN, and Todd, JL. "A Case Of Acute Fibrinous And Organizing Pneumonia Associated With Development Of Anti-Hla Antibodies After Lung Transplantation." 2015.  Link to Item
    • Chery, GS, Palmer, SM, Snyder, LD, Gray, AL, Todd, JL, Harrison, G, and Pavlisko, EN. "Post-Transplant Lymphoproliferative Disorder Erosion Into A Large Pulmonary Artery With Death Secondary To Hemorrhagic Shock." 2015.  Link to Item
    • Chery, GS, Palmer, SM, Snyder, LD, Todd, JL, and Wolfe, C. "Brincidofovir In Progressive Multifocal Leukoencephalopathy After Lung Transplant." 2015.  Link to Item
    • Copeland, CAF, Martissa, JA, Frankel, CW, Benedetti, EC, Callahan, E, Ross, D, Palmer, SM, Todd, JL, Belperio, JA, Snyder, LD, and Weigt, S. "A Prospective Multicenter Assessment Of Aztreonam Lysine For Inhalation In The Treatment Of Lung Transplant Recipients With Chronic Lung Allograft Dysfunction." 2015.  Link to Item
    • Todd, JL, Kelly, FL, Brass, DM, Kennedy, VE, Pavlisko, EN, and Palmer, SM. "Increased Amphiregulin Expression Is Associated With Chronic Allograft Dysfunction After Lung Transplantation." 2015.  Link to Item
    • Todd, JL, Kennedy, VE, Pavlisko, EN, Zhang, HL, Kelly, FL, and Palmer, SM. "Elevated Hyaluronan Is Associated with Bronchiolitis Obliterans Syndrome." : Elsevier BV, April 2014.  Full Text
    • Todd, JL, Urban, TJ, Finlen Copeland, CA, Kelly, FL, Goldstein, DB, and Palmer, SM. "Whole Exome Sequencing: A Novel Strategy to Understand Chronic Lung Allograft Dysfunction (CLAD)." : Elsevier BV, April 2014.  Full Text
    • Todd, JL, Jain, R, Pavlisko, EN, Copeland, CF, Snyder, LD, and Palmer, SM. "Restrictive Spirometry At Bronchiolitis Obliterans Syndrome Onset Predicts Worse Survival." 2013.  Link to Item

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