ConferenceRespir Res · February 17, 2026
BACKGROUND: Dysregulation of lipid metabolism is implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF). We assessed associations between circulating levels of high-density lipoprotein-cholesterol (HDL-C) and its components apolipoprotein A- ...
Full textLink to itemCite
ConferenceLung · August 27, 2025
We evaluated relationships between changes in lung function and changes in patient-reported outcomes (PROs) in 736 patients with idiopathic pulmonary fibrosis (IPF) enrolled in the IPF-PRO Registry. Weak correlations were observed between changes in percen ...
Full textLink to itemCite
ConferenceLung · October 2024
PURPOSE: We investigated whether a 52-gene signature was associated with transplant-free survival and other clinically meaningful outcomes in patients with idiopathic pulmonary fibrosis (IPF) in the IPF-PRO Registry, which enrolled patients who were and we ...
Full textLink to itemCite
ConferenceAm J Transplant · August 2021
Vaccine-preventable viral infections are associated with increased risk of morbidity and mortality in post-transplant patients on immunosuppression regimens. Therefore, we studied rates of immunity against vaccine-preventable viruses in lung transplantatio ...
Full textOpen AccessLink to itemCite
ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: CLAD, mainly manifest as bronchiolitis obliterans syndrome (BOS), is the leading cause of late death in lung recipients. BOS develops despite routine immunosuppression and its pathogenesis is poorly understood. The histological correlate of BOS is ...
Full textCite
ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: The pulmonary microbiome modulates the immune milieu in the lung allograft and is in turn influenced by external factors such as microaspiration of oropharyngeal contents. A potential driver of microaspiration is gastroesophageal reflux disease (G ...
Full textCite
ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: The occurrence of acute allograft injuries remains one of the most important factors responsible for the development of early chronic lung allograft dysfunction. We and others have previously demonstrated a consistent association between acute lun ...
Full textCite
ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: Frailty is gaining increased recognition in the evaluation of lung transplant (LTx) candidates. The Fried Frailty Phenotype (FFP) index has been the most commonly used instrument and is associated with pre- and post-transplant morbidity and mortal ...
Full textCite
ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: Diagnosis of CLAD after lung transplantation (LT) requires sustained decline in lung function and exclusion of other etiologies for the decline. The limitations of relying primarily on pulmonary function test (PFT) decline to define CLAD onset for ...
Full textCite