Scholarly Works - Book sections
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January 1, 2026
The classic definition of cancer is a disease in which cells grow uncontrollably and with the potential to invade or spread to other parts of the body. While this definition is accurate, it is also true that cancer, at its essence, is a disease of multicel ...
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January 1, 2024
Chapter 1 introduces cancer as a speciation event that is inexorably linked to multicellularity and marked by a return to unicellularity. Although each cancer arises as an independent speciation event, common ecological features drive convergent evolution ...
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January 1, 2024
Cancer is a result of the breakdown in processes governing multicellularity, leading to a population of cells that no longer abide by the cues of their multicellular context and begin to act as a population of unicellular organisms within the body. This ch ...
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January 1, 2024
This chapter summarizes the main points of the prior chapters, discusses the benefits of incorporating ecological and evolutionary perspectives into research and treatment of cancer, and highlights gaps in our knowledge. In particular, the chapter discusse ...
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January 1, 2023
Dolphins and other marine mammals possess unique adaptations that allow them to thrive in aquatic environments. While many physiological and anatomical adaptations play a clear role in marine mammal phenotypes, less is known about how genetic and molecular ...
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January 1, 2020
In the United States alone prostate cancer is responsible for nearly 70 days each day. The vast majority of these deaths are due to metastatic spread of therapy-resistant disease. Metastasis and therapy resistance are mediated by phenotypic plasticity in w ...
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