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James Dundas Lane

Professor Emeritus in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
Box 3830 Med Ctr, Durham, NC 27710
40 Duke Medicine Cir, Duke Clinics, Room 3702, Durham, NC 27710

Featured Works


Pilot Study of Caffeine Abstinence for Control of Chronic Glucose in Type 2 Diabetes.

Journal article J Caffeine Res · May 24, 2012 Featured Publication BACKGROUND: A growing body of evidence suggests that caffeinated beverages may impair chronic glucose control in type 2 diabetes. This pilot study tested the chronic effects of caffeine abstinence on glucose control in type 2 diabetic patients who were dai ... Full text Link to item Cite

Brief meditation training can improve perceived stress and negative mood.

Journal article Altern Ther Health Med · 2007 Featured Publication OBJECTIVES: To test a brief, non-sectarian program of meditation training for effects on perceived stress and negative emotion, and to determine effects of practice frequency and test the moderating effects of neuroticism (emotional lability) on treatment ... Link to item Cite

Psychosocial benefits of three formats of a standardized behavioral stress management program.

Journal article Psychosom Med · 2006 Featured Publication OBJECTIVE: Psychosocial factors are associated with increased morbidity and mortality in healthy and clinical populations. Behavioral interventions are needed to train the large number of people in the community setting who are affected by stressors to use ... Full text Link to item Cite

Treatment regimen determines the relationship between depression and glycemic control.

Journal article Diabetes Res Clin Pract · July 2005 Featured Publication UNLABELLED: Several recent studies have suggested that depression is related to poorer glycemic control in patients with type 1 diabetes, but not in type 2 diabetes. We hypothesize that complexity of self-care regimen rather than the type of diabetes, is m ... Full text Link to item Cite

Caffeine impairs glucose metabolism in type 2 diabetes.

Journal article Diabetes Care · August 2004 Featured Publication Full text Link to item Cite

Beneficial effects of noetic therapies on mood before percutaneous intervention for unstable coronary syndromes.

Journal article Nurs Res · 2004 Featured Publication BACKGROUND: Many common medical, surgical, and diagnostic procedures performed for conscious patients can be accompanied by significant anxiety. Mind-body-spirit interventions could serve as useful adjunctive treatments for the reduction of stress. OBJECTI ... Full text Link to item Cite

Hostility, race, and glucose metabolism in nondiabetic individuals.

Journal article Diabetes Care · May 2002 Featured Publication OBJECTIVE: The present study was designed to determine whether hostility is differentially related to measures of glucose metabolism in African-Americans and Caucasians. RESEARCH DESIGN AND METHODS: The relationship of hostility, as measured by a subset of ... Full text Link to item Cite

Stress management improves long-term glycemic control in type 2 diabetes.

Journal article Diabetes Care · January 2002 Featured Publication OBJECTIVE: There is conflicting evidence regarding the utility of stress management training in the treatment of diabetes. The few studies that have shown a therapeutic effect of stress management have used time-intensive individual therapy. Unfortunately, ... Full text Link to item Cite

Caffeine affects cardiovascular and neuroendocrine activation at work and home.

Journal article Psychosom Med · 2002 Featured Publication OBJECTIVE: This study investigated the effects of moderate doses of caffeine on ambulatory blood pressure and heart rate, urinary excretion of epinephrine, norepinephrine, and cortisol, and subjective measures of stress during normal activities at work and ... Full text Link to item Cite

Personality correlates of glycemic control in type 2 diabetes.

Journal article Diabetes Care · September 2000 Featured Publication OBJECTIVE: To determine whether traits of normal personality are associated with variations in glycemic control in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: A longitudinal cohort study was conducted using data from 105 type 2 diabetic pat ... Full text Link to item Cite

Caffeine deprivation affects vigilance performance and mood.

Journal article Physiol Behav · August 1998 Featured Publication The effects of brief caffeine deprivation on vigilance performance, mood, and symptoms of caffeine withdrawal were studied in habitual coffee drinkers. Thirty male and female coffee drinkers were tested twice at midday (1130 to 1330 hours) after mornings i ... Full text Link to item Cite

Binaural auditory beats affect vigilance performance and mood.

Journal article Physiol Behav · January 1998 Featured Publication When two tones of slightly different frequency are presented separately to the left and right ears the listener perceives a single tone that varies in amplitude at a frequency equal to the frequency difference between the two tones, a perceptual phenomenon ... Full text Link to item Cite

Caffeine raises blood pressure at work.

Journal article Psychosom Med · 1998 Featured Publication OBJECTIVE: The study investigated the effects of moderate doses of caffeine on ambulatory blood pressure and heart rate during workday activities. METHODS: Healthy, nonsmoking, habitual coffee drinkers (N = 21) received daily doses of 100 mg and 500 mg of ... Full text Link to item Cite

Caffeine withdrawal symptoms following brief caffeine deprivation.

Journal article Physiol Behav · December 31, 1997 Featured Publication The effects of short-term caffeine deprivation on mood, withdrawal symptoms and psychomotor performance were studied in habitual coffee drinkers. Thirty-one male and female coffee drinkers were tested twice at midday (1130 to 1330 h) 4 h after double-blind ... Full text Link to item Cite

Effects of brief caffeinated-beverage deprivation on mood, symptoms, and psychomotor performance.

Journal article Pharmacol Biochem Behav · September 1997 Featured Publication The effects of short-term deprivation of caffeinated beverages on mood, withdrawal symptoms, and psychomotor performance were studied in habitual coffee drinkers. Twenty-four male and female coffee drinkers were tested at midday (1130-1330 h) under two con ... Full text Link to item Cite

Quitting smoking raises whole blood glutathione.

Journal article Physiol Behav · November 1996 Featured Publication Cigarette smoke contains numerous oxygen free radicals that may be important in smoking-related disease pathogenesis. These free radicals may overwhelm antioxidant defenses and produce a condition of oxidative stress that can result in damage to DNA and ot ... Full text Link to item Cite

Neuroendocrine responses to caffeine in the work environment.

Journal article Psychosom Med · 1994 Featured Publication The effect of caffeine on neuroendocrine stress responses in the workplace was studied in 14 habitual coffee drinkers. Urinary catecholamine and cortisol levels were measured on 2 study days, in a 4-hour interval from morning until noon, while participants ... Full text Link to item Cite

Caffeine and cholesterol: interactions with hostility.

Journal article Psychosom Med · 1994 Featured Publication The consumption of caffeinated beverages has been linked to elevated serum cholesterol and an increased risk of coronary disease, although the relationships are inconsistent across studies and remain controversial. The effect of caffeine on cholesterol and ... Full text Link to item Cite

Respiratory sinus arrhythmia and cardiovascular responses to stress.

Journal article Psychophysiology · July 1992 Featured Publication The parasympathetic nervous system provides mechanisms that could attenuate sympathetically mediated heart rate stress responses and might have even more general antagonistic actions on stress reactivity. Individuals characterized by higher levels of paras ... Full text Link to item Cite

Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption.

Journal article Psychosom Med · 1990 Featured Publication The effects of a moderate dose of caffeine on cardiovascular and neuroendocrine stress reactivity were examined in 25 healthy male subjects selected as habitual or light consumers of caffeine. Measurements were taken under resting conditions before and aft ... Full text Link to item Cite

Cardiovascular effects of caffeine and stress in regular coffee drinkers.

Journal article Psychophysiology · March 1987 Featured Publication Full text Link to item Cite

Caffeine affects cardiovascular responses to stress.

Journal article Psychophysiology · November 1985 Featured Publication Full text Link to item Cite

Cardiovascular effects of mental arithmetic in Type A and Type B females.

Journal article Psychophysiology · January 1984 Featured Publication Full text Link to item Cite

Caffeine and cardiovascular responses to stress.

Journal article Psychosom Med · October 1983 Featured Publication Caffeine and psychologic stress have similar physiologic effects. Moderate doses of caffeine were found to elevate blood pressure in healthy, young males during periods of rest and stress. Blood pressure during stress was also significantly higher after ca ... Full text Link to item Cite

Type A behavior and elevated physiological and neuroendocrine responses to cognitive tasks.

Journal article Science · October 29, 1982 Featured Publication Qualitatively distinct patterns of cardiovascular and neuroendocrine responses were observed in male college students during mental work and during sensory intake task performance. During mental work, Type A (coronary-prone) subjects showed greater muscle ... Full text Link to item Cite