Jeffrey Giles Gaca | Scholars@Duke

Jeffrey Giles Gaca
Associate Professor - Track IV of Surgery

Current Appointments & Affiliations

Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2017

Contact Information

Box 31174 Med Ctr, Durham, NC 27710
Dept Of Surgery, Durham, NC 27710
jeffrey.gaca@duke.edu (919) 613-5672

Background
Education, Training, & Certifications
- M.D., Columbia University 1998
Duke Appointment History
- Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2016 - 2017
- Assistant Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2008 - 2015
Research
Selected Grants
- PORTICO awarded by St. Jude Medical Inc. 2014 - 2022
- Core Clinical Centers for the CTSN awarded by National Institutes of Health 2007 - 2018
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Smith, PJ, Browndyke, JN, Monge, ZA, Harshbarger, TB, James, ML, Gaca, JG, Alexander, JH, Berger, MM, Newman, MF, Milano, CA, Mathew, JP, and Neurologic Outcomes Research Group (NORG), . "Longitudinal Changes in Regional Cerebral Perfusion and Cognition After Cardiac Operation." The Annals of Thoracic Surgery 107, no. 1 (January 2019): 112-118. Full Text Open Access Copy
  - Inohara, T, Manandhar, P, Kosinski, AS, Matsouaka, RA, Kohsaka, S, Mentz, RJ, Thourani, VH, Carroll, JD, Kirtane, AJ, Bavaria, JE, Cohen, DJ, Kiefer, TL, Gaca, JG, Kapadia, SR, Peterson, ED, and Vemulapalli, S. "Association of Renin-Angiotensin Inhibitor Treatment With Mortality and Heart Failure Readmission in Patients With Transcatheter Aortic Valve Replacement." Jama 320, no. 21 (December 2018): 2231-2241. Full Text
  - Zwischenberger, BA, Barac, YD, Wang, A, Gaca, JG, and Glower, DD. "Is Septal Myectomy Needed During Mitral Replacement for Hypertrophic Obstructive Cardiomyopathy?." The Annals of Thoracic Surgery 106, no. 6 (December 2018): 1892-null. (Letter) Full Text
  - Wang, A, Gaca, JG, and Chu, VH. "Injection Drug Use-Associated Infective Endocarditis-Reply." Jama 320, no. 18 (November 2018): 1939-1940. (Letter) Full Text
  - Waldron, NH, Cooter, M, Haney, JC, Schroder, JN, Gaca, JG, Lin, SS, Sigurdsson, MI, Fudim, M, Podgoreanu, MV, Stafford-Smith, M, Milano, CA, Piccini, JP, and Mathew, JP. "Temporary autonomic modulation with botulinum toxin type A to reduce atrial fibrillation after cardiac surgery." Heart Rhythm (October 26, 2018). Full Text
  - McCartney, SL, and Gaca, JG. "Invited Commentary: A Case of Multiple Ventricular Gradients." Journal of Cardiothoracic and Vascular Anesthesia 32, no. 4 (August 2018): 1833-1834. Full Text
  - Wang, A, Gaca, JG, and Chu, VH. "Management Considerations in Infective Endocarditis: A Review." Jama 320, no. 1 (July 2018): 72-83. (Review) Full Text
  - Barac, YD, Zwischenberger, B, Schroder, JN, Daneshmand, MA, Haney, JC, Gaca, JG, Wang, A, Milano, CA, and Glower, DD. "Using a Regent Aortic Valve in a Small Annulus Mitral Position Is a Viable Option." The Annals of Thoracic Surgery 105, no. 4 (April 2018): 1200-1204. Full Text
  - Friedman, DJ, Piccini, JP, Wang, T, Zheng, J, Malaisrie, SC, Holmes, DR, Suri, RM, Mack, MJ, Badhwar, V, Jacobs, JP, Gaca, JG, Chow, S-C, Peterson, ED, and Brennan, JM. "Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery." Jama 319, no. 4 (January 2018): 365-374. Full Text
  - Karhausen, JA, Smeltz, AM, Akushevich, I, Cooter, M, Podgoreanu, MV, Stafford-Smith, M, Martinelli, SM, Fontes, ML, and Kertai, MD. "Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery." Anesthesia and Analgesia 125, no. 4 (October 2017): 1129-1139. Full Text Open Access Copy
  - Teeter, EG, Dakik, C, Cooter, M, Samad, Z, Ghadimi, K, Harrison, JK, Gaca, J, Stafford-Smith, M, and Bottiger, BA. "Assessment of Paravalvular Leak After Transcatheter Aortic Valve Replacement: Transesophageal Echocardiography Compared With Transthoracic Echocardiography." Journal of cardiothoracic and vascular anesthesia 31, no. 4 (August 2017): 1278-1284. Full Text
  - Patel, PA, Ackermann, AM, Augoustides, JGT, Ender, J, Gutsche, JT, Giri, J, Vallabhajosyula, P, Desai, ND, Kostibas, M, Brady, MB, Eoh, EJ, Gaca, JG, Thompson, A, and Fitzsimons, MG. "Anesthetic Evolution in Transcatheter Aortic Valve Replacement: Expert Perspectives From High-Volume Academic Centers in Europe and the United States." Journal of Cardiothoracic and Vascular Anesthesia 31, no. 3 (June 2017): 777-790. (Review) Full Text
  - Iribarne, A, Keenan, J, Benrashid, E, Wang, H, Meza, JM, Ganapathi, A, Gaca, JG, Kim, HW, Hurwitz, LM, and Hughes, GC. "Imaging Surveillance After Proximal Aortic Operations: Is it Necessary?." The Annals of Thoracic Surgery 103, no. 3 (March 2017): 734-741. Full Text
  - Wang, A, McCartney, SL, Williams, JB, Ganapathi, A, Glower, DD, Nicoara, A, and Gaca, JG. "Use of Adjuncts Reduces Cardiopulmonary Bypass Time During Minimally Invasive Aortic Valve Replacement." The Journal of heart valve disease 26, no. 2 (March 2017): 155-160.
  - Browndyke, JN, Berger, M, Harshbarger, TB, Smith, PJ, White, W, Bisanar, TL, Alexander, JH, Gaca, JG, Welsh-Bohmer, K, Newman, MF, and Mathew, JP. "Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings." Journal of the American Geriatrics Society 65, no. 1 (January 2017): e6-e12. Full Text Open Access Copy
  - Kertai, MD, Zhou, S, Karhausen, JA, Cooter, M, Jooste, E, Li, Y-J, White, WD, Aronson, S, Podgoreanu, MV, Gaca, J, Welsby, IJ, Levy, JH, Stafford-Smith, M, Mathew, JP, and Fontes, ML. "In Reply." Anesthesiology 125, no. 2 (August 2016): 438-439. (Letter) Full Text
  - Shah, AA, Glower, DD, and Gaca, JG. "Trans-aortic Alfieri stitch at the time of septal myectomy for hypertrophic obstructive cardiomyopathy." Journal of cardiac surgery 31, no. 8 (August 2016): 503-506. Full Text
  - Yerokun, BA, Williams, JB, Gaca, J, Smith, PK, and Roe, MT. "Indications, algorithms, and outcomes for coronary artery bypass surgery in patients with acute coronary syndromes." Coronary Artery Disease 27, no. 4 (June 2016): 319-326. (Review) Full Text
  - Andersen, ND, Benrashid, E, Ross, AK, Pickett, LC, Smith, PK, Daneshmand, MA, Schroder, JN, Gaca, JG, and Hughes, GC. "The utility of the aortic dissection team: outcomes and insights after a decade of experience." Annals of cardiothoracic surgery 5, no. 3 (May 2016): 194-201. Full Text
  - Ranney, DN, Williams, JB, Wang, A, and Gaca, JG. "Valve-in-Valve Transcatheter Valve Implantation in the Nonaortic Position." Journal of Cardiac Surgery 31, no. 5 (May 2016): 282-288. Full Text
  - Hanna, JM, Keenan, JE, Wang, H, Andersen, ND, Gaca, JG, Lombard, FW, Welsby, IJ, and Hughes, GC. "Use of human fibrinogen concentrate during proximal aortic reconstruction with deep hypothermic circulatory arrest." The Journal of thoracic and cardiovascular surgery 151, no. 2 (February 2016): 376-382. Full Text
  - Kertai, MD, Zhou, S, Karhausen, JA, Cooter, M, Jooste, E, Li, Y-J, White, WD, Aronson, S, Podgoreanu, MV, Gaca, J, Welsby, IJ, Levy, JH, Stafford-Smith, M, Mathew, JP, and Fontes, ML. "Platelet Counts, Acute Kidney Injury, and Mortality after Coronary Artery Bypass Grafting Surgery." Anesthesiology 124, no. 2 (February 2016): 339-352. Full Text Open Access Copy
  - Williams, J, Sherwood, MM, Wang, A, and Gaca, JG. "Balloon-Expandable Device for Non-Aortic Valve in Valve Transcatheter Heart Valve Implantation." CARDIOLOGY 134, no. 2 (January 1, 2016): 239-239. Link to Item
  - Stafford-Smith, M, Li, Y-J, Mathew, JP, Li, Y-W, Ji, Y, Phillips-Bute, BG, Milano, CA, Newman, MF, Kraus, WE, Kertai, MD, Shah, SH, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci." Kidney international 88, no. 4 (October 2015): 823-832. Full Text Open Access Copy
  - Cherry, AD, Nicoara, A, McQuilkin, SH, Gaca, JG, and Del Rio, JM. "Multimodal Evaluation of Aortic Regurgitation After Mitral and Tricuspid Valve Repairs." Anesthesia and analgesia 121, no. 2 (August 2015): 319-322. Full Text
  - Esper, SA, Bottiger, BA, Ginsberg, B, Del Rio, JM, Glower, DD, Gaca, JG, Stafford-Smith, M, Neuburger, PJ, and Chaney, MA. "CASE 8--2015. Paravertebral Catheter-Based Strategy for Primary Analgesia After Minimally Invasive Cardiac Surgery." Journal of cardiothoracic and vascular anesthesia 29, no. 4 (August 2015): 1071-1080. Full Text
  - Tang, P, Onaitis, M, Gaca, JG, Milano, CA, Stafford-Smith, M, and Glower, D. "Right Minithoracotomy Versus Median Sternotomy for Mitral Valve Surgery: A Propensity Matched Study." The Annals of thoracic surgery 100, no. 2 (August 2015): 575-581. Full Text
  - Ganapathi, AM, Hirji, SA, Wang, A, Patel, CB, Gaca, JG, and Schroder, JN. "Bridge to long-term mechanical circulatory support with a left ventricular assist device: novel use of transcatheter aortic valve replacement." The Annals of thoracic surgery 99, no. 4 (April 2015): e91-e93. Full Text
  - Walker, WL, Boll, DT, Bueno, JM, Kiefer, TL, Vavalle, JP, Gaca, JG, Harrison, JK, Hughes, GC, Wang, A, and Hurwitz, LM. "Assessment of single-bolus contrast administration technique using hybrid dual-source ECG-gated thoracic and dual-source non-ECG-gated high-pitch abdominopelvic CT acquisitions for procedural planning before transcatheter aortic valve replacement." Journal of computer assisted tomography 39, no. 2 (March 2015): 207-212. Full Text
  - "Assessment of single-bolus contrast administration technique using hybrid dual-source ECG-gated thoracic and dual-source non-ECG-gated high-pitch abdominopelvic CT acquisitions for procedural planning before transcatheter aortic valve replacement." Journal of Computer Assisted Tomography 39, no. 2 (January 1, 2015): 207-212. Full Text
  - Ganapathi, AM, Hanna, JM, Schechter, MA, Englum, BR, Castleberry, AW, Gaca, JG, and Hughes, GC. "Antegrade versus retrograde cerebral perfusion for hemiarch replacement with deep hypothermic circulatory arrest: does it matter? A propensity-matched analysis." The Journal of Thoracic and Cardiovascular Surgery 148, no. 6 (December 2014): 2896-2902. Full Text
  - Andersen, ND, Hanna, JM, Ganapathi, AM, Bhattacharya, SD, Williams, JB, Gaca, JG, McCann, RL, and Hughes, GC. "Insurance status predicts acuity of thoracic aortic operations." The Journal of thoracic and cardiovascular surgery 148, no. 5 (November 2014): 2082-2086. Full Text
  - DeLong, MR, Hughes, DB, Gaca, JG, Fischer, JP, Bond, JE, Hargrove, WC, Atluri, P, Levin, LS, and Erdmann, D. "Sternal talon offers a solution for secondary sternum osteosynthesis in patients with nonunion." The Annals of thoracic surgery 98, no. 5 (November 2014): 1804-1808. Full Text
  - Harskamp, RE, Brennan, JM, Xian, Y, Halkos, ME, Puskas, JD, Thourani, VH, Gammie, JS, Taylor, BS, de Winter, RJ, Kim, S, O'Brien, S, Peterson, ED, and Gaca, JG. "Practice patterns and clinical outcomes after hybrid coronary revascularization in the United States: an analysis from the society of thoracic surgeons adult cardiac database." Circulation 130, no. 11 (September 2014): 872-879. Full Text
  - Andersen, ND, Ganapathi, AM, Hanna, JM, Williams, JB, Gaca, JG, and Hughes, GC. "Outcomes of acute type a dissection repair before and after implementation of a multidisciplinary thoracic aortic surgery program." Journal of the American College of Cardiology 63, no. 17 (May 2014): 1796-1803. Full Text
  - Andersen, ND, Keenan, JE, Ganapathi, AM, Gaca, JG, McCann, RL, and Hughes, GC. "Current management and outcome of chronic type B aortic dissection: results with open and endovascular repair since the advent of thoracic endografting." Annals of Cardiothoracic Surgery 3, no. 3 (May 2014): 264-274. Full Text
  - Ganapathi, AM, Andersen, ND, Hanna, JM, Gaca, JG, McCann, RL, and Hughes, GC. "Comparison of attachment site endoleak rates in Dacron versus native aorta landing zones after thoracic endovascular aortic repair." J Vasc Surg 59, no. 4 (April 2014): 921-929. Full Text Link to Item
  - Glower, DD, Desai, BS, Hughes, GC, Milano, CA, and Gaca, JG. "Aortic valve replacement via right minithoracotomy versus median sternotomy: a propensity score analysis." Innovations (Philadelphia, Pa.) 9, no. 2 (March 2014): 75-81. Full Text
  - James, ML, Andersen, ND, Swaminathan, M, Phillips-Bute, B, Hanna, JM, Smigla, GR, Barfield, ME, Bhattacharya, SD, Williams, JB, Gaca, JG, Husain, AM, and Hughes, GC. "Predictors of electrocerebral inactivity with deep hypothermia." The Journal of Thoracic and Cardiovascular Surgery 147, no. 3 (March 2014): 1002-1007. Full Text
  - Ganapathi, AM, Englum, BR, Hanna, JM, Schechter, MA, Gaca, JG, Hurwitz, LM, and Hughes, GC. "Frailty and risk in proximal aortic surgery." The Journal of Thoracic and Cardiovascular Surgery 147, no. 1 (January 2014): 186-191.e1. Full Text
  - Lombard, FW, and Welsby, IJ. "Reduced use of allogeneic platelets through high-yield perioperative autologous plateletpheresis and reinfusion." Transfusion 54, no. 5 (January 1, 2014): 1348-1357. Full Text
  - Gaca, JG, Clare, RM, Rankin, JS, Daneshmand, MA, Milano, CA, Hughes, GC, Wolfe, WG, Glower, DD, and Smith, PK. "Risk-adjusted survival after tissue versus mechanical aortic valve replacement: a 23-year assessment." The Journal of heart valve disease 22, no. 6 (November 2013): 810-816.
  - Gaca, JG, Sheng, S, Daneshmand, M, Rankin, JS, Williams, ML, O'Brien, SM, and Gammie, JS. "Current outcomes for tricuspid valve infective endocarditis surgery in North America." Ann Thorac Surg 96, no. 4 (October 2013): 1374-1381. Full Text Link to Item
  - Kiefer, TL, Vavalle, J, Halim, S, Kaul, P, Klein, JL, Hurwitz, LH, Gaca, JG, and Harrison, JK. "Anterograde percutaneous coronary-cameral fistula closure employing a guide-in-guide technique." JACC Cardiovasc Interv 6, no. 10 (October 2013): 1105-1107. Full Text Link to Item
  - Tang, P, Onaitis, M, Desai, B, Gaca, JG, Milano, CA, Stafford-Smith, M, and Glower, DD. "Minithoracotomy versus sternotomy for mitral surgery in patients with chronic renal impairment: a propensity-matched study." Innovations (Philadelphia, Pa.) 8, no. 5 (September 2013): 325-331. Full Text
  - Parsa, CJ, Shaw, LK, Rankin, JS, Daneshmand, MA, Gaca, JG, Milano, CA, Glower, DD, and Smith, PK. "Twenty-five-year outcomes after multiple internal thoracic artery bypass." The Journal of Thoracic and Cardiovascular Surgery 145, no. 4 (April 2013): 970-975. Full Text
  - Aronson, S, Phillips-Bute, B, Stafford-Smith, M, Fontes, M, Gaca, J, Mathew, JP, and Newman, MF. "The association of postcardiac surgery acute kidney injury with intraoperative systolic blood pressure hypotension." Anesthesiol Res Pract 2013 (2013): 174091-. Full Text Open Access Copy Link to Item
  - Hughes, GC, Zhao, Y, Rankin, JS, Scarborough, JE, O'Brien, S, Bavaria, JE, Wolfe, WG, Gaca, JG, Gammie, JS, Shahian, DM, and Smith, PK. "Effects of institutional volumes on operative outcomes for aortic root replacement in North America." The Journal of Thoracic and Cardiovascular Surgery 145, no. 1 (January 2013): 166-170. Full Text
  - Rankin, JS, Daneshmand, MA, Milano, CA, Gaca, JG, Glower, DD, and Smith, PK. "Mitral valve repair for ischemic mitral regurgitation: review of current techniques." Heart Lung Vessel 5, no. 4 (2013): 246-251. Link to Item
  - Andersen, ND, Bhattacharya, SD, Williams, JB, Fosbol, EL, Lockhart, EL, Patel, MB, Gaca, JG, Welsby, IJ, and Hughes, GC. "Intraoperative use of low-dose recombinant activated factor VII during thoracic aortic operations." The Annals of thoracic surgery 93, no. 6 (June 2012): 1921-1928. Full Text
  - Bennett-Guerrero, E, Phillips-Bute, B, Waweru, PM, Gaca, JG, Spann, JC, and Milano, CA. "Pilot study of sternal plating for primary closure of the sternum in cardiac surgical patients." Innovations (Phila) 6, no. 6 (November 2011): 382-388. Full Text Link to Item
  - Lima, B, Williams, JB, Bhattacharya, SD, Shah, AA, Andersen, N, Gaca, JG, and Hughes, GC. "Results of proximal arch replacement using deep hypothermia for circulatory arrest: is moderate hypothermia really justifiable?." The American surgeon 77, no. 11 (November 2011): 1438-1444.
  - Rankin, JS, and Gaca, JG. "Techniques of aortic valve repair." Innovations (Phila) 6, no. 6 (November 2011): 348-354. Full Text Link to Item
  - Rankin, JS, Gaca, JG, Brunsting, LA, Daneshmand, MA, Milano, CA, Glower, DD, and Smith, PK. "Increasing mitral valve repair rates with nonresectional techniques." Innovations (Phila) 6, no. 4 (July 2011): 209-220. Full Text Link to Item
  - Swaminathan, M, Nicoara, A, Phillips-Bute, BG, Aeschlimann, N, Milano, CA, Mackensen, GB, Podgoreanu, MV, Velazquez, EJ, Stafford-Smith, M, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery." Ann Thorac Surg 91, no. 6 (June 2011): 1844-1850. Full Text Link to Item
  - Gaca, JG, Sheng, S, Daneshmand, MA, O'Brien, S, Rankin, JS, Brennan, JM, Hughes, GC, Glower, DD, Gammie, JS, and Smith, PK. "Outcomes for endocarditis surgery in North America: a simplified risk scoring system." The Journal of Thoracic and Cardiovascular Surgery 141, no. 1 (January 2011): 98-106.e1-2-null. Full Text
  - Parsa, CJ, Daneshmand, MA, Gaca, JG, and Rankin, JS. "Arterial bypass grafting of the coronary circulation." HSR Proc Intensive Care Cardiovasc Anesth 3, no. 4 (2011): 227-234. Link to Item
  - Aronson, S, Stafford-Smith, M, Phillips-Bute, B, Shaw, A, Gaca, J, Newman, M, and Cardiothoracic Anesthesiology Research Endeavors, . "Intraoperative systolic blood pressure variability predicts 30-day mortality in aortocoronary bypass surgery patients." Anesthesiology 113, no. 2 (August 2010): 305-312. Full Text
  - Nikolov, NM, Fontes, ML, White, WD, Aronson, S, Bar-Yosef, S, Gaca, JG, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Pulse pressure and long-term survival after coronary artery bypass graft surgery." Anesthesia and Analgesia 110, no. 2 (February 2010): 335-340. Full Text
  - Rajagopal, K, Rogers, JG, Lodge, AJ, Gaca, JG, McCann, RL, Milano, CA, and Hughes, GC. "Two-stage total cardioaortic replacement for end-stage heart and aortic disease in Marfan syndrome: case report and review of the literature." J Heart Lung Transplant 28, no. 9 (September 2009): 958-963. (Review) Full Text Link to Item
  - Gaca, JG, Lima, B, Milano, CA, Lin, SS, Davis, RD, Lowe, JE, and Smith, PK. "Laser-assisted extraction of pacemaker and defibrillator leads: the role of the cardiac surgeon." Ann Thorac Surg 87, no. 5 (May 2009): 1446-1450. Full Text Link to Item
  - Cantu, E, Balsara, KR, Li, B, Lau, C, Gibson, S, Wyse, A, Baig, K, Gaca, J, Gonzalez-Stawinski, GV, Nichols, T, Parker, W, and Davis, RD. "Prolonged function of macrophage, von Willebrand factor-deficient porcine pulmonary xenografts." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 7, no. 1 (January 2007): 66-75. Full Text
  - Gaca, JG, Appel, JZ, Lukes, JG, Gonzalez-Stawinski, GV, Lesher, A, Palestrant, D, Logan, JS, Love, SD, Holzknecht, ZE, Platt, JL, Parker, W, and Davis, RD. "Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction." Transplantation 81, no. 12 (June 2006): 1686-1694. Full Text
  - Cantu, E, Gaca, JG, Palestrant, D, Baig, K, Lukes, DJ, Gibson, SE, Gonzalez-Stawinski, GV, Olausson, M, Parker, W, and Davis, RD. "Depletion of pulmonary intravascular macrophages prevents hyperacute pulmonary xenograft dysfunction." Transplantation 81, no. 8 (April 2006): 1157-1164. Full Text
  - Gaca, JG, Petersen, RP, Peterson, BL, Harpole, DH, D'Amico, TA, Pappas, TN, Seigler, HF, Wolfe, WG, and Tyler, DS. "Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma." Ann Surg Oncol 13, no. 3 (March 2006): 340-346. Full Text Link to Item
  - Lukes, DJ, Cantu, E, Gaca, JG, Hallberg, E, Karlsson-Parra, A, Parker, W, Olausson, M, and Davis, RD. "Oral feeding with pig peripheral lymphocytes decreases the xenogeneic delayed type hypersensitivity reaction in galactosyltransferase knockout mice." Transplant Proc 37, no. 8 (October 2005): 3327-3331. Full Text Link to Item
  - Fields, RC, Baig, K, Gaca, J, Milton, LG, Koch, WJ, and Lawson, JH. "Reduction of vascular intimal-medial hyperplasia in polytetrafluoroethylene arteriovenous grafts via expression of an inhibitor of G protein signaling." Annals of Vascular Surgery 19, no. 5 (September 2005): 712-718. Full Text
  - Baig, K, Fields, RC, Gaca, J, Hanish, S, Milton, LG, Koch, WJ, and Lawson, JH. "A porcine model of intimal-medial hyperplasia in polytetrafluoroethylene arteriovenous grafts." J Vasc Access 4, no. 3 (July 2003): 111-117. Link to Item
  - Gaca, JG, Palestrant, D, Lukes, DJ, Olausson, M, Parker, W, and Davis, RD. "Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate." The Journal of Surgical Research 112, no. 1 (June 2003): 19-25. Full Text
  - Gaca, JG, Lesher, A, Aksoy, O, Ruggeri, ZM, Parker, W, and Davis, RD. "The role of the porcine von Willebrand factor: baboon platelet interactions in pulmonary xenotransplantation." Transplantation 74, no. 11 (December 2002): 1596-1603. Full Text
  - Lau, CL, Palmer, SM, Howell, DN, McMahon, R, Hadjiliadis, D, Gaca, J, Pappas, TN, Davis, RD, and Eubanks, S. "Laparoscopic antireflux surgery in the lung transplant population." Surg Endosc 16, no. 12 (December 2002): 1674-1678. Full Text Link to Item
  - Gaca, JG, Lesher, A, Aksoy, O, Gonzalez-Stawinski, GV, Platt, JL, Lawson, JH, Parker, W, and Davis, RD. "Disseminated intravascular coagulation in association with pig-to-primate pulmonary xenotransplantation." Transplantation 73, no. 11 (June 15, 2002): 1717-1723. Link to Item
  - Gonzalez-Stawinski, GV, Daggett, CW, Lau, CL, Karoor, S, Love, SD, Logan, JS, Gaca, JG, Parker, W, and Davis, RD. "Non-anti-Gal alpha1-3Gal antibody mechanisms are sufficient to cause hyperacute lung dysfunction in pulmonary xenotransplantation." Journal of the American College of Surgeons 194, no. 6 (June 2002): 765-773. Full Text
  - Lee, W, Gaca, JG, Edwards, LA, Braedehoeft, SJ, Parker, W, and Davis, RD. "Binding of polyreactive antibodies to self versus foreign antigens." Immunobiology 205, no. 1 (March 2002): 95-107. Full Text
  - Gaca, JG, Lee, W, Aksoy, O, Braedehoeft, SJ, Gonzalez-Stawinski, GV, Parker, W, and Davis, RD. "Evidence for polyreactive xenoreactive antibodies in the repertoire of human anti-swine antibodies: the 'next' humoral barrier to xenotransplantation?." Transpl Immunol 9, no. 1 (October 2001): 19-27. Link to Item
- Book Sections
  - "Thoracoabdominal aortic aneurysms." In Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management: Seventh Edition, 241-276. January 18, 2012.
- Other Articles
  - Kiefer, TL, Halim, S, Wang, A, Kevin Harrison, J, Gaca, J, and Hughes, GC. "Fluoroscopic characterization of surgical bioprosthetic heart valves." Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 85, no. 7 (June 2015): 1274-1276. (Letter) Full Text
  - Kertai, MD, Li, Y-W, Li, Y-J, Shah, SH, Kraus, WE, Fontes, ML, Stafford-Smith, M, Newman, MF, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers." Circulation. Cardiovascular Genetics 7, no. 5 (October 2014): 625-633. Full Text
  - McDonagh, DL, Mathew, JP, White, WD, Phillips-Bute, B, Laskowitz, DT, Podgoreanu, MV, Newman, MF, and Neurologic Outcome Research Group, . "Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury." Anesthesiology 112, no. 4 (April 2010): 852-859. Full Text
- Conference Papers
  - Yerokun, BA, Karhausen, J, Ranney, DN, Benrashid, E, Wang, H, Keenan, J, Schroder, J, Daneshmand, M, Gaca, JG, and Hughes, GC. "Does Deeper Hypothermia Reduce the Risk of Acute Kidney Injury After Circulatory Arrest for Aortic Arch Surgery?." Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium. Anaheim, CA. November 11, 2017 - November 15, 2017.: LIPPINCOTT WILLIAMS & WILKINS, November 14, 2017. Link to Item
  - Wang, H, Wagner, M, Benrashid, E, Keenan, J, Wang, A, Ranney, D, Yerokun, B, Gaca, JG, McCann, RL, and Hughes, GC. "Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy." October 3, 2017. Full Text
  - Mavroudis, C, Gaca, J, and Sade, RM. "Can a Surgeon Refuse to Operate When an Advance Directive Limits Postoperative Care?." October 2016. Full Text
  - Vavalle, JP, Cowper, P, Nelson, JA, Hurwitz, L, Hughes, GC, Wang, A, Gaca, JG, Kiefer, T, Halim, S, Alexander, JH, and Harrison, JK. "Inpatient and Outpatient Resource Utilization in the Evaluation and Management of Patients With Aortic Stenosis Being Considered for Transcatheter Aortic Valve Replacement (TAVR)." November 26, 2013. Link to Item
  - Harskamp, RE, Brennan, JM, Gaca, JG, Halkos, ME, Peterson, ED, Rao, SV, Williams, JB, De Winter, RJ, Alexander, JH, and Lopes, RD. "A systematic review of outcomes related to hybrid coronary revascularization in patients with multi-vessel coronary artery disease in the drug-eluting stent era." August 2013. Link to Item
  - Andersen, ND, Hanna, JM, Bhattacharya, SD, Williams, JB, Gaca, JG, McCann, RL, and Hughes, GC. "Insurance status predicts non-elective case status but not outcomes of thoracic aortic operations." September 2012. Full Text
  - Hughes, GC, Zhao, Y, Rankin, JS, O'Brien, S, Bavaria, JE, Wolfe, WG, Gaca, JG, Gammie, JS, Shahian, DM, and Smith, PK. "Effects of Institutional Volumes on Operative Outcomes for Combined Aortic Valve and Ascending Aortic Surgery." November 23, 2010. Link to Item
  - Cantu, E, Gaca, JG, Lukes, DJ, Palestrant, D, Baig, K, Gonzalez-Stawinski, GV, Parker, W, and Davis, RD. "Abrogation of hyperacute pulmonary xenograft dysfunction by passenger macrophage depletion." 2004. Link to Item
  - Cantu, E, Gaca, JG, Lukes, DJ, Palestrant, D, Baig, K, Gonzalez-Stawinski, G, Parker, W, and Davis, RD. "Passenger pulmonary macrophages play a key role in the coagulopathy and endothelial activation associated with pulmonary xenograft dysfunction." September 2003. Link to Item
  - Cantu, E, Gaca, JG, Lukes, FJ, Palestrant, D, Baig, K, Gonzalez-Stawinski, G, Parker, W, and Davis, RD. "Depletion of porcine pulmonary intravascular macrophages attenuates hyperacute pulmonary xenograft dysfunction." September 2003. Link to Item
  - Cantu, E, Gibson, S, Wyse, A, Lau, C, Gaca, JG, Gonzalez-Stawinski, G, Baig, K, Nichols, T, Parker, W, and Davis, RD. "Role of porcine von Willebrand factor in pulmonary xenograft injury." September 2003. Link to Item
  - Gaca, JG, Harpole, DH, D'Amico, TA, Pappas, T, Seigler, HF, Wolfe, WG, and Tyler, S. "Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma." July 2002. Link to Item

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