Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., North Carolina State University 2000
• 

  Previous Appointments & Affiliations

  • Assistant Professor in Pathology, Pathology, Clinical Science Departments 2020 - 2021
  • Assistant Professor in Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2006 - 2021
  • Assistant Professor in Pathology, Pathology, Clinical Science Departments 2018 - 2020
  • Assistant Professor in the Department of Surgery, Surgery, Surgical Sciences, Surgery 2018 - 2020
  • Instructor, Temporary in the Department of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine 2006
• Research
• 

  Selected Grants

  • Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER) awarded by National Institutes of Health 2022 - 2026
  • The Role of PON2 in the Development of Non-Allergic Asthma in Obesity awarded by National Institutes of Health 2022 - 2024
  • Oxidative Stress and Regional Airway Remodeling and Fibrosis in Obese Asthma awarded by National Institutes of Health 2020 - 2024
  • Research Training in Allergy and Clinical Immunology awarded by University of North Carolina - Chapel Hill 2000 - 2023
  • Mechanisms that Direct Airway Remodeling in Obese Asthma awarded by National Institutes of Health 2017 - 2023
  • Mechanisms that Direct Airway Remodeling in Obese Asthma awarded by American Lung Association 2014 - 2016
• 

  External Relationships

  • AMD
  • ASML
  • Adobe Systems
  • Albemarle Corp
  • American Thoracic Society
  • Blackstone Group Inc
  • Broadcom
  • ESTC
  • First Trust Cloud Computing ETF
  • India Alliance - Wellcome Trust
  • Ingram Management Group LLC
  • JP Morgan Chase
  • Owl Rock Capital Corp
  • Qualcomm, Inc.
  • Rio Tinto
  • Tesla
  • Twilio Inc
  • United Rentals
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • McCravy, Matthew S., and Jennifer L. Ingram. “A Hint from Wnt: Squamous Cell Differentiation in the Airways.” Am J Respir Cell Mol Biol 68, no. 6 (June 2023): 601–2. https://doi.org/10.1165/rcmb.2023-0065ED.
       Full Text  Link to Item
    • Kim, Haein R., Jennifer L. Ingram, and Loretta G. Que. “Effects of Oxidative Stress on Airway Epithelium Permeability in Asthma and Potential Implications for Patients with Comorbid Obesity.” Journal of Asthma and Allergy 16 (January 2023): 481–99. https://doi.org/10.2147/jaa.s402340.
       Full Text
    • Womble, Jack T., Mark D. Ihrie, Victoria L. McQuade, Akhil Hegde, Matthew S. McCravy, Sanat Phatak, Robert M. Tighe, et al. “Vertical sleeve gastrectomy associates with airway hyperresponsiveness in a murine model of allergic airway disease and obesity.” Front Endocrinol (Lausanne) 14 (2023): 1092277. https://doi.org/10.3389/fendo.2023.1092277.
       Full Text  Link to Item
    • Tseng, Victor, Scott D. Collum, Ayed Allawzi, Kathryn Crotty, Samantha Yeligar, Aaron Trammell, M. Ryan Smith, et al. “3'UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension.” Matrix Biol 111 (August 2022): 53–75. https://doi.org/10.1016/j.matbio.2022.06.001.
       Full Text  Open Access Copy  Link to Item
    • Ihrie, Mark D., Victoria L. McQuade, Jack T. Womble, Akhil Hegde, Matthew S. McCravy, Cyrus Victor G. Lacuesta, Robert M. Tighe, Loretta G. Que, Julia K. L. Walker, and Jennifer L. Ingram. “Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease.” Respir Res 23, no. 1 (May 24, 2022): 131. https://doi.org/10.1186/s12931-022-02048-z.
       Full Text  Open Access Copy  Link to Item
    • Adeloye, Davies, Omer Elneima, Luke Daines, Krisnah Poinasamy, Jennifer K. Quint, Samantha Walker, Chris E. Brightling, et al. “The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease.” Lancet Respir Med 9, no. 12 (December 2021): 1467–78. https://doi.org/10.1016/S2213-2600(21)00286-1.
       Full Text  Open Access Copy  Link to Item
    • Kim, Yeon Ji, Jack T. Womble, Claudia K. Gunsch, and Jennifer L. Ingram. “The Gut/Lung Microbiome Axis in Obesity, Asthma, and Bariatric Surgery: A Literature Review.” Obesity (Silver Spring) 29, no. 4 (April 2021): 636–44. https://doi.org/10.1002/oby.23107.
       Full Text  Open Access Copy  Link to Item
    • Al Alam, Denise, Philip L. Ballard, Claude Jourdan Le Saux, Jennifer L. Ingram, Thomas J. Mariani, Nuala S. Moore, Daniel J. Weiss, and Michelle Yu. “Human Fetal Tissue Regulation. Impact on Pediatric and Adult Respiratory-related Research.” Ann Am Thorac Soc 18, no. 2 (February 2021): 204–8. https://doi.org/10.1513/AnnalsATS.202005-460PS.
       Full Text  Link to Item
    • McCravy, Matthew, Jennifer L. Ingram, and Loretta G. Que. “Dysregulated Metabolism in the Pathophysiology of Non-Allergic Obese Asthma.” J Asthma Allergy 14 (2021): 179–86. https://doi.org/10.2147/JAA.S282284.
       Full Text  Open Access Copy  Link to Item
    • Womble, Jack T., Victoria L. McQuade, Mark D. Ihrie, and Jennifer L. Ingram. “Imbalanced Coagulation in the Airway of Type-2 High Asthma with Comorbid Obesity.” J Asthma Allergy 14 (2021): 967–80. https://doi.org/10.2147/JAA.S318017.
       Full Text  Open Access Copy  Link to Item
    • Drake, Matthew G., Nirav G. Shah, May Lee, Anna Brady, Geoffrey R. Connors, Brendan J. Clark, Patricia A. Kritek, et al. “Development of a National Academic Boot Camp to Improve Fellowship Readiness.” Ats Sch 2, no. 1 (December 22, 2020): 49–65. https://doi.org/10.34197/ats-scholar.2020-0091OC.
       Full Text  Open Access Copy  Link to Item
    • Ingram, Jennifer L. “Give Me Some Room to Breathe! Can Targeting SPHK2 Reduce Airway Smooth Muscle Thickening in Asthma?” Am J Respir Cell Mol Biol 62, no. 1 (January 2020): 1–2. https://doi.org/10.1165/rcmb.2019-0240ED.
       Full Text  Open Access Copy  Link to Item
    • Ihrie, Mark D., and Jennifer L. Ingram. “Orchestrating Airway Smooth Muscle Cell Migration: GMFγ Phosphorylation Is the Key.” Am J Respir Cell Mol Biol 61, no. 2 (August 2019): 136–38. https://doi.org/10.1165/rcmb.2019-0074ED.
       Full Text  Open Access Copy  Link to Item
    • Guerron, Alfredo D., Camila B. Ortega, Hui-Jie Lee, Gerardo Davalos, Jennifer Ingram, and Dana Portenier. “Asthma medication usage is significantly reduced following bariatric surgery.” Surg Endosc 33, no. 6 (June 2019): 1967–75. https://doi.org/10.1007/s00464-018-6500-x.
       Full Text  Open Access Copy  Link to Item
    • Verhoef, Philip A., and Jennifer L. Ingram. “When It Comes to Alternaria, Instant CARMA's Gonna Get You.” Am J Respir Cell Mol Biol 59, no. 6 (December 2018): 657–58. https://doi.org/10.1165/rcmb.2018-0186ED.
       Full Text  Open Access Copy  Link to Item
    • Lugogo, Njira, Dave Francisco, Kenneth J. Addison, Akarsh Manne, William Pederson, Jennifer L. Ingram, Cynthia L. Green, et al. “Obese asthmatic patients have decreased surfactant protein A levels: Mechanisms and implications.” J Allergy Clin Immunol 141, no. 3 (March 2018): 918-926.e3. https://doi.org/10.1016/j.jaci.2017.05.028.
       Full Text  Open Access Copy  Link to Item
    • Walker, Julia K. L., Barbara S. Theriot, Michael Ghio, Carol S. Trempus, Jordan E. Wong, Victoria L. McQuade, Jiurong Liang, et al. “Targeted HAS2 Expression Lessens Airway Responsiveness in Chronic Murine Allergic Airway Disease.” Am J Respir Cell Mol Biol 57, no. 6 (December 2017): 702–10. https://doi.org/10.1165/rcmb.2017-0095OC.
       Full Text  Open Access Copy  Link to Item
    • Trempus, Carol S., Weifeng Song, Ahmed Lazrak, Zhihong Yu, Judy R. Creighton, Bethany M. Young, Rebecca L. Heise, et al. “A novel role for primary cilia in airway remodeling.” Am J Physiol Lung Cell Mol Physiol 313, no. 2 (August 1, 2017): L328–38. https://doi.org/10.1152/ajplung.00284.2016.
       Full Text  Open Access Copy  Link to Item
    • Hackett, Tillie-Louise, Sarah C. Ferrante, Claire E. Hoptay, John F. Engelhardt, Jennifer L. Ingram, Yulong Zhang, Sarah E. Alcala, et al. “A Heterotopic Xenograft Model of Human Airways for Investigating Fibrosis in Asthma.” Am J Respir Cell Mol Biol 56, no. 3 (March 2017): 291–99. https://doi.org/10.1165/rcmb.2016-0065MA.
       Full Text  Open Access Copy  Link to Item
    • Ingram, Jennifer L., David Slade, Tony D. Church, Dave Francisco, Karissa Heck, R Wesley Sigmon, Michael Ghio, et al. “Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13-Suppressed Elastin in Airway Fibroblasts in Asthma.” Am J Respir Cell Mol Biol 54, no. 1 (January 2016): 41–50. https://doi.org/10.1165/rcmb.2014-0290OC.
       Full Text  Open Access Copy  Link to Item
    • Ferrante, Sarah, Tillie-Louise Hackett, John F. Engelhardt, Jennifer L. Ingram, Susan Reynolds, Yulong Zhang, Claire E. Hoptay, et al. “IN VIVO EVIDENCE IN A XENOGRAFT MODEL FOR ASTHMATIC EPITHELIUM DRIVING AIRWAY REMODELING.” Journal of Investigative Medicine 63, no. 3 (March 1, 2015): 569–569.
       Link to Item
    • Firszt, Rafael, Dave Francisco, Tony D. Church, Joseph M. Thomas, Jennifer L. Ingram, and Monica Kraft. “Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma.” Eur Respir J 43, no. 2 (February 2014): 464–73. https://doi.org/10.1183/09031936.00068712.
       Full Text  Open Access Copy  Link to Item
    • Ingram, J. L., B. Theriot, A. Hegde, J. Thomas, J. K. Walker, P. W. Noble, and M. Kraft. “Over-Expression Of Hyaluronan Synthase 2 (has2) In Contractile Cells Reduces Airways Hyperresponsiveness In A Mouse Model Of Chronic Allergic Airways Disease.” American Journal of Respiratory and Critical Care Medicine 189 (January 1, 2014).
       Link to Item
    • Ingram, Jennifer L., and Monica Kraft. “IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies.” J Allergy Clin Immunol 130, no. 4 (October 2012): 829–42. https://doi.org/10.1016/j.jaci.2012.06.034.
       Full Text  Link to Item
    • Wang, Ying, Zhou Zhu, Tony D. Church, Njira L. Lugogo, Loretta G. Que, Dave Francisco, Jennifer L. Ingram, et al. “SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells.” J Immunol 188, no. 7 (April 1, 2012): 3371–81. https://doi.org/10.4049/jimmunol.1100573.
       Full Text  Open Access Copy  Link to Item
    • “Corrigendum.” American Journal of Physiology Lung Cellular and Molecular Physiology 302, no. 3 (February 1, 2012): L360–L360. https://doi.org/10.1152/ajplung.zh5-6044-corr.2012.
       Full Text
    • Wang, Ying, Dennis R. Voelker, Njira L. Lugogo, Guirong Wang, Joanna Floros, Jennifer L. Ingram, Hong Wei Chu, et al. “Surfactant protein A is defective in abrogating inflammation in asthma.” Am J Physiol Lung Cell Mol Physiol 301, no. 4 (October 2011): L598–606. https://doi.org/10.1152/ajplung.00381.2010.
       Full Text  Open Access Copy  Link to Item
    • Liang, Jiurong, Dianhua Jiang, Yoosun Jung, Ting Xie, Jennifer Ingram, Tony Church, Simone Degan, Maura Leonard, Monica Kraft, and Paul W. Noble. “Role of hyaluronan and hyaluronan-binding proteins in human asthma.” J Allergy Clin Immunol 128, no. 2 (August 2011): 403-411.e3. https://doi.org/10.1016/j.jaci.2011.04.006.
       Full Text  Open Access Copy  Link to Item
    • Ingram, Jennifer L., Molly J. Huggins, Tony D. Church, Yuejuan Li, Dave C. Francisco, Simone Degan, Rafael Firszt, et al. “Airway fibroblasts in asthma manifest an invasive phenotype.” Am J Respir Crit Care Med 183, no. 12 (June 15, 2011): 1625–32. https://doi.org/10.1164/rccm.201009-1452OC.
       Full Text  Open Access Copy  Link to Item
    • Church, T. D., J. L. Ingram, D. Francisco, D. Beaver, D. Jinwright, and M. Kraft. “Elastin Expression Is Differentially Modulated In The Proximal And Distal Lung Compartments In Asthma.” American Journal of Respiratory and Critical Care Medicine 181 (January 1, 2010).
       Link to Item
    • Firszt, R., T. D. Church, D. Francisco, C. Hathcock, D. Beaver, J. L. Ingram, and M. Kraft. “MMP Inhibition Attenuates IL-13 Induced Procollagen 1 MRNA Expression In Human Airway Fibroblasts In Asthma.” American Journal of Respiratory and Critical Care Medicine 181 (January 1, 2010).
       Link to Item
    • Huggins, M. J., N. Lugogo, T. D. Church, J. L. Ingram, D. Francisco, R. Firszt, D. Beaver, D. Jinwright, and M. Kraft. “LL Leptin Modulates The Expression Of Procollagen 1 alpha In Airway Fibroblasts In Asthma.” American Journal of Respiratory and Critical Care Medicine 181 (January 1, 2010).
       Link to Item
    • Ingram, J. L., M. J. Huggins, T. D. Church, D. Francisco, R. Firszt, S. Degan, P. W. Noble, D. Beaver, M. E. Sunday, and M. Kraft. “Interleukin-13 Induces Airway Fibroblast Invasion In Asthma: Implications For A Mechanism Dependent On MMPs And TGF-beta.” American Journal of Respiratory and Critical Care Medicine 181 (January 1, 2010).
       Link to Item
    • Ingram, J. L., M. J. Huggins, T. D. Church, D. Francisco, D. M. Beaver, and M. Kraft. “Dexamethasone Modulates IL-13 and IL-4 Receptor Subunit Expression in Airway Fibroblasts in Asthma.” American Journal of Respiratory and Critical Care Medicine 179 (January 1, 2009).
       Link to Item
    • Kraft, M., K. B. Adler, J. L. Ingram, A. L. Crews, T. P. Atkinson, C. B. Cairns, D. C. Krause, and H. W. Chu. “Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma.” Eur Respir J 31, no. 1 (January 2008): 43–46. https://doi.org/10.1183/09031936.00103307.
       Full Text  Link to Item
    • Ingram, Jennifer L., Aurita Antao-Menezes, Elizabeth A. Turpin, Duncan G. Wallace, James B. Mangum, Linda J. Pluta, Russell S. Thomas, and James C. Bonner. “Genomic analysis of human lung fibroblasts exposed to vanadium pentoxide to identify candidate genes for occupational bronchitis.” Respir Res 8, no. 1 (April 25, 2007): 34. https://doi.org/10.1186/1465-9921-8-34.
       Full Text  Link to Item
    • Ingram, Jennifer L., Aurita Antao-Menezes, James B. Mangum, Otis Lyght, Patty J. Lee, Jack A. Elias, and James C. Bonner. “Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts.” J Immunol 177, no. 6 (September 15, 2006): 4141–48. https://doi.org/10.4049/jimmunol.177.6.4141.
       Full Text  Link to Item
    • Ingram, Jennifer L., and James C. Bonner. “EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases.” Curr Mol Med 6, no. 4 (June 2006): 409–21. https://doi.org/10.2174/156652406777435426.
       Full Text  Link to Item
    • Walters, Dianne M., Aurita Antao-Menezes, Jennifer L. Ingram, Annette B. Rice, Abraham Nyska, Yoshiro Tani, Steven R. Kleeberger, and James C. Bonner. “Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis.” Am J Pathol 167, no. 5 (November 2005): 1221–29. https://doi.org/10.1016/S0002-9440(10)61210-2.
       Full Text  Link to Item
    • Ingram, Jennifer L., Annette B. Rice, Kristen Geisenhoffer, David K. Madtes, and James C. Bonner. “IL-13 and IL-1beta promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Ralpha.” Faseb J 18, no. 10 (July 2004): 1132–34. https://doi.org/10.1096/fj.03-1492fje.
       Full Text  Link to Item
    • Wang, Yi-Zhe, Jennifer L. Ingram, Dianne M. Walters, Annette B. Rice, Janine H. Santos, Bennett Van Houten, and James C. Bonner. “Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase.” Free Radic Biol Med 35, no. 8 (October 15, 2003): 845–55. https://doi.org/10.1016/s0891-5849(03)00399-x.
       Full Text  Link to Item
    • Ingram, Jennifer L., Annette B. Rice, Janine Santos, Bennett Van Houten, and James C. Bonner. “Vanadium-induced HB-EGF expression in human lung fibroblasts is oxidant dependent and requires MAP kinases.” Am J Physiol Lung Cell Mol Physiol 284, no. 5 (May 2003): L774–82. https://doi.org/10.1152/ajplung.00189.2002.
       Full Text  Link to Item
    • Ingram, J. L., A. Rice, K. Geisenhoffer, D. K. Madtes, and J. C. Bonner. “Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: A possible mechanism for the development of airway fibrosis in asthma.” Chest 123, no. 3 SUPPL. (March 1, 2003): 422S-424S.
    • Ingram, Jennifer L., Annette Rice, Kristen Geisenhoffer, David K. Madtes, and James C. Bonner. “Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma.” Chest 123, no. 3 Suppl (March 2003): 422S-424S. https://doi.org/10.1378/chest.123.3_suppl.422s.
       Full Text  Link to Item
    • Rice, Annette B., Jennifer L. Ingram, and James C. Bonner. “p38 mitogen-activated protein kinase regulates growth factor-induced mitogenesis of rat pulmonary myofibroblasts.” Am J Respir Cell Mol Biol 27, no. 6 (December 2002): 759–65. https://doi.org/10.1165/rcmb.2002-0070OC.
       Full Text  Link to Item
    • Bonner, James C., Annette B. Rice, Jennifer L. Ingram, Cindy R. Moomaw, Abraham Nyska, Alyce Bradbury, Alisha R. Sessoms, et al. “Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis.” Am J Pathol 161, no. 2 (August 2002): 459–70. https://doi.org/10.1016/S0002-9440(10)64202-2.
       Full Text  Link to Item
    • Ascenzi, R., J. L. Ingram, M. Massel, W. F. Thompson, S. Spiker, and A. K. Weissinger. “The role of cell differentiation state and HMG-I/Y in the expression of transgenes flanked by matrix attachment regions.” Transgenic Res 10, no. 5 (October 2001): 465–70. https://doi.org/10.1023/a:1012082602587.
       Full Text  Link to Item

  • Conference Papers

    • Ihrie, M. D., V. L. Mcquade, J. T. Womble, J. M. Daly, R. M. Tighe, L. G. Que, and J. L. Ingram. “A Role for MMP-19 in Mediating the Effects of Vertical Sleeve Gastrectomy in Chronically Allergen-Challenged Obese Mice.” In American Journal of Respiratory and Critical Care Medicine, Vol. 205, 2022.
       Link to Item
    • Mcquade, V., M. Ihrie, J. Womble, K. Zhao, H. Kim, L. G. Que, and J. L. Ingram. “Leptin Augments Human Airway Fibroblast Invasion and IL-13-Induced Eotaxin Production in a Murine Model of Allergic Airway Disease.” In American Journal of Respiratory and Critical Care Medicine, Vol. 205, 2022.
       Link to Item
    • Ihrie, M., V. Mcquade, A. Hegde, C. Lacuesta, J. Womble, M. S. Mccravy, L. G. Que, J. K. Walker, and J. L. Ingram. “Vertical Sleeve Gastrectomy in Chronically Allergen-Challenged Obese Mice Increases Airway Hyperresponsiveness.” In American Journal of Respiratory and Critical Care Medicine, Vol. 203, 2021.
       Link to Item
    • Mccravy, M. S., V. Mcquade, M. Ihrie, J. Womble, L. G. Que, and J. L. Ingram. “Vertical Sleeve Gastrectomy Increased PPAR. Expression in Obese Mice Challenged with House Dust Mite.” In American Journal of Respiratory and Critical Care Medicine, Vol. 203, 2021.
       Link to Item
    • Daly, J. M., Z. Yang, J. L. Ingram, K. M. Luginbuhl, A. Varanko, R. M. Tighe, A. Chilkoti, and L. G. Que. “Glucagon Like Peptide 1 Attenuates Airway Hyperresponsiveness in a Mouse Model of Obese Allergic Asthma.” In American Journal of Respiratory and Critical Care Medicine, Vol. 201, 2020.
       Link to Item
    • Ihrie, M., V. L. McQuade, C. V. Lacuesta, R. M. Tighe, L. G. Que, A. Hedge, J. K. Walker, and J. L. Ingram. “Chronic Leptin Administration in Lean, Allergen-Challenged Female Mice Promotes Small Airway Closure and Airway Fibrosis.” In American Journal of Respiratory and Critical Care Medicine, Vol. 201, 2020.
       Link to Item
    • Yang, Z., J. M. Daly, J. L. Ingram, F. Holguin, R. M. Tighe, and L. G. Que. “Deficiency in Paraoxonase 2 Increases Airway Hyper Responsiveness After Ozone Exposure in Mice.” In American Journal of Respiratory and Critical Care Medicine, Vol. 201, 2020.
       Link to Item
    • Cyphert-Daly, Jaime M., Zhonghui Yang, Jennifer L. Ingram, Robert M. Tighe, and Loretta G. Que. “Physiologic response to chronic house dust mite exposure in mice is dependent on lot characteristics.” In J Allergy Clin Immunol, 144:1428-1432.e8, 2019. https://doi.org/10.1016/j.jaci.2019.07.019.
       Full Text  Link to Item
    • Ihrie, Mark, Victoria McQuade, Akhil Hegde, Jingjing Niu, Jenny Tong, David D’Alessio, Julia K. L. Walker, Loretta G. Que, and Jennifer L. Ingram. “Sleeve gastrectomy surgery reduces airway resistance and inflammation in chronically allergen-challenged obese mice.” In Journal of Allergy and Clinical Immunology, 143:AB307–AB307. Elsevier BV, 2019. https://doi.org/10.1016/j.jaci.2018.12.935.
       Full Text
    • Yu, Y. A., J. Daly, S. Phelan, R. I. Cumming, A. Birukova, Y. Malakhau, J. L. Ingram, M. D. Gunn, L. G. Que, and R. M. Tighe. “Replacement of Fetal-Derived with Bone Marrow-Derived Pulmonary Resident Macrophages Reduces House Dust Mite-Induced Airway Hyperresponsiveness.” In American Journal of Respiratory and Critical Care Medicine, Vol. 199. AMER THORACIC SOC, 2019.
       Link to Item
    • Authelet, K., B. Harmon, S. Epstein, M. Goldberg, S. Ghose, C. Hoptay, M. Barberio, E. Nadler, J. L. Ingram, and R. J. Freishtat. “Adipocyte-Derived Exosomes Modulate Expression of Genes in TGF-beta Pathway Differently in Asthmatic Compared to Normal Fibroblasts.” In American Journal of Respiratory and Critical Care Medicine, Vol. 197. AMER THORACIC SOC, 2018.
       Link to Item
    • Ingram, J. L., V. McQuade, B. Theriot, J. Niu, J. Daly, J. Wong, J. Tong, R. M. Tighe, L. G. Que, and D. D’Alessio. “Vertical Sleeve Gastrectomy in Allergen-Challenged Obese Mice Is Associated with Reduced Airway Resistance and Fibrosis.” In American Journal of Respiratory and Critical Care Medicine, Vol. 197. AMER THORACIC SOC, 2018.
       Link to Item
    • Yang, Z., J. Daly, D. E. Winnica, F. Holguin, V. McQuade, J. L. Ingram, R. M. Tighe, and L. G. Que. “Characterization of Paraoxonases in Mice with Obese Allergic Asthma.” In American Journal of Respiratory and Critical Care Medicine, Vol. 197. AMER THORACIC SOC, 2018.
       Link to Item
    • Mcquade, Victoria L., Jingjing Niu, Barbara Theriot, David D’Alessio, Mary Jane Cunningham, Loretta Que, and Jennifer L. Ingram. “An in Vitro Model of Airway Fibroblast Functions to Assess Airway Remodeling in Asthma.” In In Vitro Cellular & Developmental Biology Animal, 53:663–663. SPRINGER, 2017.
       Link to Item
    • Ingram, J. L. “Modeling Human Lung Fibroblast Responses in Asthma and Airway Disease.” In In Vitro Cellular & Developmental Biology Animal, 53:S5–6. SPRINGER, 2017.
       Link to Item
    • Ingram, J. L., M. Ghio, A. Hegde, J. Wong, D. D’Alessio, L. Que, J. K. Walker, and V. McQuade. “Opposing Actions Of Leptin And Glucagon-Like Peptide-1 (glp-1) To Regulate Interleukin-13 (il-13)-Directed Airway Fibroblast Responses.” In American Journal of Respiratory and Critical Care Medicine, Vol. 195. AMER THORACIC SOC, 2017.
       Link to Item
    • Ferrante, S. C., T. -. L. Hackett, C. E. Hoptay, J. Engelhardt, J. L. Ingram, S. Alcala, Y. Zhang, et al. “An In Vivo Model Of Human Airways For Investigating Fibrosis.” In American Journal of Respiratory and Critical Care Medicine, Vol. 193. AMER THORACIC SOC, 2016.
       Link to Item
    • Ingram, J. L., M. Ghio, R. W. Sigmon, J. Wong, B. Theriot, A. Hegde, J. K. L. Walker, and M. Kraft. “Interleukin-17 And Leptin Contribute To Airway Fibrosis And Altered Interleukin-13 Receptor Expression In Obese Asthma.” In American Journal of Respiratory and Critical Care Medicine, Vol. 193. AMER THORACIC SOC, 2016.
       Link to Item
    • Ingram, Jennifer L., Robert W. Sigmon, Barbara Theriot, Michael Ghio, Akhil Hegde, Dave Francisco, Julia K. L. Walker, and Monica Kraft. “Leptin Modulates Airway Remodeling Processes and Responses to Interleukin-13 in Lung Fibroblasts in a Murine Model of Chronic Allergic Airways Disease.” In Journal of Allergy and Clinical Immunology, 135:AB382–AB382. Elsevier BV, 2015. https://doi.org/10.1016/j.jaci.2014.12.1876.
       Full Text
    • Ferrante, S. C., J. L. Ingram, E. Nadler, M. Hubal, J. Seo, M. Giri, D. Jung, D. K. Pillai, J. M. Wang, and R. J. Freishtat. “Asthmatic Airway Fibroblasts: Tgf beta Receptor Signaling Is Up-Regulated After Obese Visceral Adipose Exosome Exposure.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
       Link to Item
    • Ferrante, S. C., T. -. L. Hackett, J. F. Engelhardt, J. L. Ingram, S. D. Reynolds, Y. Zhang, C. E. Hoptay, et al. “In Vivo Evidence In A Xenograft Model For Asthmatic Epithelium Driving Airway Remodeling.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
       Link to Item
    • Ingram, J. L., J. Weiss, M. Ghio, D. C. Francisco, R. W. Sigmon, N. Lugogo, and M. Kraft. “Leptin Augments Interleukin-13-Induced Eotaxin-1 And Eotaxin-3 Production By Airway Fibroblasts In Asthma.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
       Link to Item
    • Ledford, J. G., N. Lugogo, N. Agada, J. Weiss, D. C. Francisco, J. L. Ingram, M. E. Sunday, L. G. Que, and M. Kraft. “Increased Tissue Eosinophilia In Obese Asthma May Be Due To Decreased Surfactant Protein-A Levels.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
       Link to Item
    • Ingram, J. L., B. Theriot, D. Francisco, T. Church, D. Slade, D. Beaver, N. Lugogo, J. Walker, and M. Kraft. “Obesity Influences Airway Fibroblast Invasiveness And Extracellular Matrix Expression In Asthma: Implications For The Pathobiology Of Airway Remodeling In Distinct Asthma Endotypes.” In American Journal of Respiratory and Critical Care Medicine, Vol. 187. AMER THORACIC SOC, 2013.
       Link to Item
    • Ingram, J. L., D. Slade, D. Francisco, T. Church, D. Beaver, and M. Kraft. “Matrix Metalloproteinase 1 (mmp-1) Mediates Interleukin-13 (il-13)-Induced Suppression Of Elastin Expression In Airway Fibroblasts In Asthma.” In American Journal of Respiratory and Critical Care Medicine, Vol. 187. AMER THORACIC SOC, 2013.
       Link to Item
    • Firszt, R., T. D. Church, D. Francisco, D. Beaver, J. L. Ingram, and M. Kraft. “MMP-2 Inhibition Attenuates IL-13 Induced Collagen Type-1 mRNA Expression in Human Airway Fibroblasts in Asthma.” In Journal of Allergy and Clinical Immunology, 127:AB127–AB127. Elsevier BV, 2011. https://doi.org/10.1016/j.jaci.2010.12.509.
       Full Text
    • Firszt, R., T. D. Church, D. Francisco, J. L. Ingram, and M. Kraft. “IL-13 Induces Procollagen 1 mRNA Expression in Human Airway Fibroblasts in Asthma.” In Journal of Allergy and Clinical Immunology, 125:AB106–AB106. Elsevier BV, 2010. https://doi.org/10.1016/j.jaci.2009.12.416.
       Full Text

  • Preprints

    • Tighe, Robert M., Anastasiya Birukova, Yuryi Malakhau, Yoshihiko Kobayashi, Aaron T. Vose, Vidya Chandramohan, Jaime M. Cyphert-Daly, et al. “Allergic Asthma Responses Are Dependent on Macrophage Ontogeny.,” February 16, 2023. https://doi.org/10.1101/2023.02.16.528861.
       Full Text  Link to Item

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.