Jennifer Leigh Ingram

Preprint · 2025 Background Diabetes mellitus is associated with a cluster of hand manifestations—including Dupuytren’s disease (DD), flexor tenosynovitis (FT), limited joint mobility (LJM), and carpal tunnel syndrome (CTS)—collectively termed the “diabetic hand.” ... Full text Cite

Prospective validation of mean metacarpophalangeal joint extension as a measure of flexor compartment fibrotic inflammation in diabetes-related hand manifestations

Preprint · 2024 Introduction Hand conditions in diabetes, namely limited joint mobility (LJM), flexor tenosynovitis (FT), carpal tunnel syndrome (CTS), and Dupuytren disease (DD), share a common pathophysiological process involving pro-fibrotic inflammation in fl ... Full text Cite

Allergic Asthma Responses Are Dependent on Macrophage Ontogeny.

Preprint · February 16, 2023 The ontogenetic composition of tissue-resident macrophages following injury, environmental exposure, or experimental depletion can be altered upon re-establishment of homeostasis. However, the impact of altered resident macrophage ontogenetic milieu on sub ... Full text Link to item Cite

Is metacarpophalangeal joint restriction an indicator of blood pressure?

Preprint · 2023 Arterial wall stiffness is implicated in the etiopathogenesis of hypertension, reflecting medial stiffness and atherosclerotic plaques. In individuals with diabetes, musculoskeletal phenotypes like limited joint mobility (LJM) in the hands suggests soft ti ... Full text Cite

Quantification of joint mobility limitation in adult type 1 diabetes

Preprint · 2023 Background Diabetic cheiroarthropathies consist of limited joint mobility (LJM), flexor tenosynovitis (FTS), Dupuytren’s contracture (DC), and carpal tunnel syndrome (CTS). There is heterogeneity in definitions and lack of a method to measure hand ... Full text Cite