Current Appointments & Affiliations
Assistant Professor in Medicine
·
2021 - Present
Medicine, Infectious Diseases,
Medicine
Recent Publications
Integration of genomic and pharmacokinetic data to predict clinical outcomes in HIV-associated cryptococcal meningitis.
Journal Article mBio · October 16, 2024 UNLABELLED: Cryptococcal meningitis causes an estimated 112,000 global deaths per annum. Genomic and phenotypic features of the infecting strain of Cryptococcus spp. have been associated with outcomes from cryptococcal meningitis. Additionally, population- ... Full text Link to item CiteStructures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans: A target for antifungals.
Journal Article Proc Natl Acad Sci U S A · August 6, 2024 Invasive fungal diseases are a major threat to human health, resulting in more than 1.5 million annual deaths worldwide. The arsenal of antifungal therapeutics remains limited and is in dire need of drugs that target additional biosynthetic pathways that a ... Full text Link to item CiteEfficacy of Liposomal Nystatin in a Rabbit Model of Cryptococcal Meningitis.
Journal Article J Fungi (Basel) · July 26, 2024 Cryptococcal meningitis (CM) causes significant global morbidity and mortality. Current therapeutic strategies rely on deoxycholated or liposomal forms of the polyene amphotericin B. Nystatin is also a polyene with broad-spectrum antimicrobial activity. Tr ... Full text Link to item CiteRecent Grants
Advancing genomic, transcriptomic and functional approaches to combat globally important and emerging pathogens (U19)
ResearchResearch Scientist · Awarded by Broad Institute · 2019 - 2025Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDS
ResearchLaboratory Manager · Awarded by National Institutes of Health · 2011 - 2024AM-2-19 Efficacy Testing in a Mouse Model of Cryptococcosis
ResearchAssociate in Research · Awarded by Sfunga Therapeutics · 2022 - 2023View All Grants
Education, Training & Certifications
University of Basel (Switzerland) ·
2003
Ph.D.
University of Wisconsin, Madison ·
1998
M.S.