Current Appointments & Affiliations
Assistant Professor in Medicine
·
2021 - Present
Medicine, Infectious Diseases,
Medicine
Recent Publications
Vaccine-Mediated Protection of Mice Against African and Asian Clinical Strains of Cryptococcus neoformans.
Journal Article J Fungi (Basel) · December 16, 2025 Infections with strains of the Cryptococcus neoformans species complex are responsible for over 100,000 deaths per year, predominantly due to meningitis in immunocompromised individuals. Despite much research, there are no licensed fungal vaccines availabl ... Full text Link to item CiteInhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways.
Journal Article mBio · October 8, 2025 Infections caused by fungal pathogens such as Candida and Cryptococcus are associated with high mortality rates, partly due to limitations in the current antifungal arsenal. This highlights the need for antifungal drug targets with novel mechanisms of acti ... Full text Link to item CiteIntegration of genomic and pharmacokinetic data to predict clinical outcomes in HIV-associated cryptococcal meningitis.
Journal Article mBio · October 16, 2024 UNLABELLED: Cryptococcal meningitis causes an estimated 112,000 global deaths per annum. Genomic and phenotypic features of the infecting strain of Cryptococcus spp. have been associated with outcomes from cryptococcal meningitis. Additionally, population- ... Full text Link to item CiteRecent Grants
Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDS
ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2030Advancing genomic, transcriptomic and functional approaches to combat globally important and emerging pathogens (U19)
ResearchResearch Scientist · Awarded by Broad Institute · 2019 - 2027Efficacy, Pharmacokinetics, and Pharmacodynamics of APX2039 in a Rabbit Model of Cryptococcal Meningitis
ResearchInvestigator · Awarded by Basilea Pharmaceutica International Ltd, Allschwil · 2025 - 2026View All Grants
Education, Training & Certifications
University of Basel (Switzerland) ·
2003
Ph.D.
University of Wisconsin, Madison ·
1998
M.S.