Jesse David Troy | Scholars@Duke

Jesse David Troy
Assistant Professor of Pediatrics

I am a medical statistician who provides statistical support for research studies in stem cell transplantation and cell therapies for a variety of indications including cerebral palsy (CP), brain injury, autism, cancer, and stroke. My personal research interests are related to medical decision making and patient-centered outcomes in hematologic malignancies. I currently serve as the Scientific Director of the Data Coordinating Center for the National MDS Study (http://www.thenationalmdsstudy.net). I also developed and currently teach a course in introductory biostatistics that is required for graduation from the Duke MD degree program, and a course in research study design required for the Master's degree in Biostatistics. Before coming to Duke I worked as a Project Manager/Biostatistician at a large data coordinating center that supported an NIH-funded extramural research programs, including vaccine development and blood and marrow transplantation. I received my PhD in cancer epidemiology from the University of Pittsburgh in 2012 where I was funded by a National Cancer Institute R25 training grant. Prior to completing my PhD I received an MPH from George Washington University. I spent the early part of my career working as a software engineer for Booz Allen Hamilton, AmericaOnline (AOL), and others. I have dedicated my career to learning from data for the purpose of serving patients and their families and continually seek collaboration with other researchers who share my passion and interest in exploring innovative ways to analyze data from medical research studies.

Current Appointments & Affiliations

Assistant Professor of Pediatrics, Pediatrics, Blood and Marrow Transplantation, Pediatrics 2014

Contact Information

2400 Pratt St, Box 3850, Durham, NC 27705
3850, Durham, NC 27705
jesse.troy@duke.edu (919) 668-2932

Background
Education, Training, & Certifications
- Ph.D., University of Pittsburgh 2012
Expertise
Subject Headings
Research
Selected Grants
- Marcus Foundation Phase II MSC ASD 2019 - 2022
- High Fidelity Diffusion MRI for Children with Cerebral Palsy in Stem Cell Therapy awarded by National Institutes of Health 2012 - 2022
- EMMES Sub Contract 2015
Industry Relationships
- Aegis-CN
- Cohortias, International
- Gamida-Cell, Ltd.
- Rx Statistics
- The Community Data Roundtable
- The EMMES Corporation
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Moffet, J. R., K. M. Mahadeo, J. McArthur, D. D. Hsing, S. J. Gertz, L. S. Smith, A. Loomis, et al. “Correction to: Acute respiratory failure and the kinetics of neutrophil recovery in pediatric hematopoietic cell transplantation: a multicenter study..” Bone Marrow Transplant, December 10, 2019. https://doi.org/10.1038/s41409-019-0767-y.
    Full Text Link to Item
  - Sekeres, Mikkael A., Steven D. Gore, Donald M. Stablein, Nancy DiFronzo, Gregory A. Abel, Amy E. DeZern, Jesse D. Troy, et al. “The National MDS Natural History Study: design of an integrated data and sample biorepository to promote research studies in myelodysplastic syndromes..” Leuk Lymphoma 60, no. 13 (December 2019): 3161–71. https://doi.org/10.1080/10428194.2019.1616186.
    Full Text Link to Item
  - Moffet, J. R., K. M. Mahadeo, J. McArthur, D. D. Hsing, S. J. Gertz, L. S. Smith, A. Loomis, et al. “Acute respiratory failure and the kinetics of neutrophil recovery in pediatric hematopoietic cell transplantation: a multicenter study..” Bone Marrow Transplant, September 16, 2019. https://doi.org/10.1038/s41409-019-0649-3.
    Full Text Link to Item
  - Troy, Jesse D., Susan C. Locke, Greg P. Samsa, Joseph Feliciano, Akshara Richhariya, and Thomas W. LeBlanc. “Patient-reported distress in Hodgkin lymphoma across the survivorship continuum..” Support Care Cancer 27, no. 7 (July 2019): 2453–62. https://doi.org/10.1007/s00520-018-4523-4.
    Full Text Link to Item
  - Kamal, Arif H., Steven P. Wolf, Jesse Troy, Victoria Leff, Constance Dahlin, Joseph D. Rotella, George Handzo, Phillip E. Rodgers, and Evan R. Myers. “Policy Changes Key To Promoting Sustainability And Growth Of The Specialty Palliative Care Workforce..” Health Aff (Millwood) 38, no. 6 (June 2019): 910–18. https://doi.org/10.1377/hlthaff.2019.00018.
    Full Text Link to Item
  - Allewelt, Heather, Mahsa Taskindoust, Jesse Troy, Kristin Page, Susan Wood, Suhag Parikh, Vinod K. Prasad, and Joanne Kurtzberg. “Long-Term Functional Outcomes after Hematopoietic Stem Cell Transplant for Early Infantile Krabbe Disease..” Biol Blood Marrow Transplant 24, no. 11 (November 2018): 2233–38. https://doi.org/10.1016/j.bbmt.2018.06.020.
    Full Text Open Access Copy Link to Item
  - Laskowitz, Daniel T., Ellen R. Bennett, Rebecca J. Durham, John J. Volpi, Jonathan R. Wiese, Michael Frankel, Elizabeth Shpall, Jeffry M. Wilson, Jesse Troy, and Joanne Kurtzberg. “Allogeneic Umbilical Cord Blood Infusion for Adults with Ischemic Stroke: Clinical Outcomes from a Phase I Safety Study..” Stem Cells Transl Med 7, no. 7 (July 2018): 521–29. https://doi.org/10.1002/sctm.18-0008.
    Full Text Link to Item
  - Han, Peng, Hongliang Liu, Qiong Shi, Zhensheng Liu, Jesse D. Troy, Walter T. Lee, Jose P. Zevallos, Guojun Li, Erich M. Sturgis, and Qingyi Wei. “Associations between expression levels of nucleotide excision repair proteins in lymphoblastoid cells and risk of squamous cell carcinoma of the head and neck..” Mol Carcinog 57, no. 6 (June 2018): 784–93. https://doi.org/10.1002/mc.22801.
    Full Text Open Access Copy Link to Item
  - Troy, Jesse D., Carlos M. de Castro, Mary Ruth Pupa, Greg P. Samsa, Amy P. Abernethy, and Thomas W. LeBlanc. “Patient-Reported Distress in Myelodysplastic Syndromes and Its Association With Clinical Outcomes: A Retrospective Cohort Study..” J Natl Compr Canc Netw 16, no. 3 (March 2018): 267–73. https://doi.org/10.6004/jnccn.2017.7048.
    Full Text Link to Item
  - Sun, Jessica M., Allen W. Song, Laura E. Case, Mohamad A. Mikati, Kathryn E. Gustafson, Ryan Simmons, Ricki Goldstein, et al. “Effect of Autologous Cord Blood Infusion on Motor Function and Brain Connectivity in Young Children with Cerebral Palsy: A Randomized, Placebo-Controlled Trial..” Stem Cells Transl Med 6, no. 12 (December 2017): 2071–78. https://doi.org/10.1002/sctm.17-0102.
    Full Text Link to Item
  - Patel, Sachit A., Heather A. Allewelt, Jesse D. Troy, Paul L. Martin, Timothy A. Driscoll, Vinod K. Prasad, Joanne Kurtzberg, Kristin M. Page, and Suhag H. Parikh. “Durable Chimerism and Long-Term Survival after Unrelated Umbilical Cord Blood Transplantation for Pediatric Hemophagocytic Lymphohistiocytosis: A Single-Center Experience..” Biol Blood Marrow Transplant 23, no. 10 (October 2017): 1722–28. https://doi.org/10.1016/j.bbmt.2017.06.013.
    Full Text Link to Item
  - Page, Kristin M., Myriam Labopin, Annalisa Ruggeri, Gerard Michel, Cristina Diaz de Heredia, Tracey O’Brien, Alessandra Picardi, et al. “Factors Associated with Long-Term Risk of Relapse after Unrelated Cord Blood Transplantation in Children with Acute Lymphoblastic Leukemia in Remission..” Biol Blood Marrow Transplant 23, no. 8 (August 2017): 1350–58. https://doi.org/10.1016/j.bbmt.2017.04.015.
    Full Text Link to Item
  - Dawson, Geraldine, Jessica M. Sun, Katherine S. Davlantis, Michael Murias, Lauren Franz, Jesse Troy, Ryan Simmons, Maura Sabatos-DeVito, Rebecca Durham, and Joanne Kurtzberg. “Autologous Cord Blood Infusions Are Safe and Feasible in Young Children with Autism Spectrum Disorder: Results of a Single-Center Phase I Open-Label Trial..” Stem Cells Transl Med 6, no. 5 (May 2017): 1332–39. https://doi.org/10.1002/sctm.16-0474.
    Full Text Link to Item
  - Han, Peng, Fengqin Gao, Hongliang Liu, Zhensheng Liu, Qiong Shi, Jesse D. Troy, Kouros Owzar, et al. “Reduced mRNA expression of nucleotide excision repair genes in lymphocytes and risk of squamous cell carcinoma of the head and neck..” Carcinogenesis 38, no. 5 (May 1, 2017): 504–10. https://doi.org/10.1093/carcin/bgx028.
    Full Text Link to Item
  - Saha, Arjun, Susan Buntz, Paula Scotland, Li Xu, Pamela Noeldner, Sachit Patel, Amy Wollish, et al. “A cord blood monocyte-derived cell therapy product accelerates brain remyelination..” Jci Insight 1, no. 13 (August 18, 2016). https://doi.org/10.1172/jci.insight.86667.
    Full Text Link to Item
  - Shoulars, Kevin, Pamela Noldner, Jesse D. Troy, Lynn Cheatham, Amanda Parrish, Kristin Page, Tracy Gentry, Andrew E. Balber, and Joanne Kurtzberg. “Development and validation of a rapid, aldehyde dehydrogenase bright-based cord blood potency assay..” Blood 127, no. 19 (May 12, 2016): 2346–54. https://doi.org/10.1182/blood-2015-08-666990.
    Full Text Open Access Copy Link to Item
  - Troy, Jesse D., Heather R. Hill, Marian G. Ewell, and Sharon E. Frey. “Sex difference in immune response to vaccination: A participant-level meta-analysis of randomized trials of IMVAMUNE smallpox vaccine..” Vaccine 33, no. 41 (October 5, 2015): 5425–31. https://doi.org/10.1016/j.vaccine.2015.08.032.
    Full Text Link to Item
  - Troy, Jesse D., Ehab Atallah, Julia T. Geyer, and Wael Saber. “Myelodysplastic syndromes in the United States: an update for clinicians..” Ann Med 46, no. 5 (August 2014): 283–89. https://doi.org/10.3109/07853890.2014.898863.
    Full Text Link to Item
  - Atallah, Ehab, Kathryn Bylow, Jesse Troy, and Wael Saber. “Treatment of older patients with high-risk myelodysplastic syndromes (MDS): the emerging role of allogeneic hematopoietic stem cell transplantation (Allo HSCT)..” Curr Hematol Malig Rep 9, no. 1 (March 2014): 57–65. https://doi.org/10.1007/s11899-013-0195-9.
    Full Text Link to Item
  - Troy, Jesse D., Joel L. Weissfeld, Ada O. Youk, Sufi Thomas, Lin Wang, and Jennifer R. Grandis. “Expression of EGFR, VEGF, and NOTCH1 suggest differences in tumor angiogenesis in HPV-positive and HPV-negative head and neck squamous cell carcinoma..” Head Neck Pathol 7, no. 4 (December 2013): 344–55. https://doi.org/10.1007/s12105-013-0447-y.
    Full Text Link to Item
  - Troy, Jesse D., Jennifer R. Grandis, Ada O. Youk, Brenda Diergaarde, Marjorie Romkes, and Joel L. Weissfeld. “Childhood passive smoke exposure is associated with adult head and neck cancer..” Cancer Epidemiol 37, no. 4 (August 2013): 417–23. https://doi.org/10.1016/j.canep.2013.03.011.
    Full Text Link to Item
  - Troy, Jesse D., Joel L. Weissfeld, Brenda Diergaarde, Ada O. Youk, Shama C. Buch, Marjorie Romkes, and Jennifer R. Grandis. “Polymorphisms in NAT2 and GSTP1 are associated with survival in oral and oropharyngeal cancer..” Cancer Epidemiol 37, no. 4 (August 2013): 505–11. https://doi.org/10.1016/j.canep.2013.02.009.
    Full Text Link to Item
  - Troy, Jesse D., Patricia Hartge, Joel L. Weissfeld, Martin M. Oken, Graham A. Colditz, Leah E. Mechanic, and Lindsay M. Morton. “Associations between anthropometry, cigarette smoking, alcohol consumption, and non-Hodgkin lymphoma in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial..” Am J Epidemiol 171, no. 12 (June 15, 2010): 1270–81. https://doi.org/10.1093/aje/kwq085.
    Full Text Link to Item
- Conference Papers
  - Stafford, Lauren, Jesse Troy, Timothy Driscoll, Kristin Page, Suhag Parikh, Vinod Prasad, Joanne Kurtzberg, and Paul Martin. “OUTCOMES OF SUBSEQUENT TRANSPLANT FOR PATIENTS WITH HEMATOLOGICAL MALIGNANCIES WHO RELAPSE.” In Pediatric Blood & Cancer, Vol. 66. WILEY, 2019.
    Link to Item
  - LeBlanc, Thomas William, Susan C. Locke, Kris Herring, Debra M. Davis, Jesse D. Troy, Karen E. Steinhauser, Kathryn I. Pollak, and Peter A. Ubel. “A video decision aid to improve acute myeloid leukemia patients' illness understanding: Results of a pilot trial..” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.
    Link to Item
  - Saha, A., A. Gunaratne, L. Xu, P. Scotland, J. Schwartzman, N. Williams, J. D. Troy, A. Balber, A. J. Filiano, and J. Kurtzberg. “Human umbilical cord blood derived cell therapy product, DUOC-01, ameliorates experimental autoimmune encephalomyelitis, a mouse model for multiple sclerosis.” In Cytotherapy, 21:S55–S55. Elsevier BV, 2019. https://doi.org/10.1016/j.jcyt.2019.03.425.
    Full Text
  - Muñiz Alers, Saisha M., Kristin Page, Ryan Simmons, Barbara Waters-Pick, Lynn Cheatham, Jesse D. Troy, and Joanne Kurtzberg. “Automated thawing increases recovery of colony-forming units from banked cord blood unit grafts..” In Transfusion, 58:2911–17, 2018. https://doi.org/10.1111/trf.14938.
    Full Text Link to Item
  - Vallely, Jaxon, Jesse D. Troy, Susan C. Locke, and Thomas William LeBlanc. “Psychological distress in myelodysplastic syndromes..” In Journal of Clinical Oncology, 36:e19027–e19027. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.e19027.
    Full Text
  - Troy, Jesse D., Susan C. Locke, Mary Ruth Pupa, Joseph Feliciano, Akshara Richhariya, and Thomas W. LeBlanc. “Patient-Reported Distress in Hodgkin Lymphoma Patients on Active Therapy Vs. Long-Term Survivors.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.
    Link to Item
  - Troy, Jesse D., Carlos deCastro, Mary Ruth Pupa, Greg P. Samsa, Amy Pickar Abernethy, and Thomas William LeBlanc. “Patient-reported distress in myelodysplastic syndromes and its relationship with clinical outcomes..” In Journal of Clinical Oncology, 35:e21564–e21564. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.e21564.
    Full Text
  - Kurtzberg, Joanne, Jesse D. Troy, Ellen Bennett, Samir Belagaje, Elizabeth J. Shpall, Jonathan Wiese, John Volpi, and Daniel Laskowitz. “Allogeneic Umbilical Cord Blood Infusion for Adults with Ischemic Stroke (CoBIS): Clinical Outcomes from a Phase 1 Safety Study.” In Blood, 128:2284–2284. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.2284.2284.
    Full Text
  - Troy, Jesse D., Carlos deCastro, Mary Ruth Pupa, Greg P. Samsa, Amy Pickar Abernethy, and Thomas William LeBlanc. “Patient-reported distress in adults with myelodysplastic syndromes (MDS)..” In Journal of Clinical Oncology, 34:80–80. American Society of Clinical Oncology (ASCO), 2016. https://doi.org/10.1200/jco.2016.34.26_suppl.80.
    Full Text
  - Allewelt, Heather, Mahsa Taskindoust, Jesse Troy, Kristin Page, Susan Wood, Suhag Parikh, Vinod Prasad, and Joanne Kurtzberg. “Long-Term Functional Outcomes Following Hematopoietic Stem Cell Transplantation for Early Infantile Krabbe Disease.” In Transfusion, 56:7A-8A. WILEY-BLACKWELL, 2016.
    Link to Item
  - Allewelt, Heather B., Kristin Page, Mahsa Taskindoust, Jesse D. Troy, Susan Wood, Suhag Parikh, Vinod K. Prasad, and Joanne Kurtzberg. “Long-Term Functional Outcomes following Hematopoietic Stem Cell Transplantation for Krabbe Disease.” In Biology of Blood and Marrow Transplantation, 22:S102–3. Elsevier BV, 2016. https://doi.org/10.1016/j.bbmt.2015.11.405.
    Full Text
  - Page, Kristin, Jose Hernandez, Jesse D. Troy, Ana Valverde Vidal, and Joanne Kurtzberg. “Targeting Cord Blood Units with Higher Total Nucleated Cell Count for Inclusion in a Public Cord Blood Bank: Impact on Inventory Diversity and Self-Sustainability.” In Biology of Blood and Marrow Transplantation, 22:S81–S81. Elsevier BV, 2016. https://doi.org/10.1016/j.bbmt.2015.11.375.
    Full Text
  - Sun, Jessica, Mohamad Mikati, Jesse D. Troy, Kathryn Gustafson, Ryan Simmons, Ricki Goldstein, Jodi Petry, et al. “Adequately Dosed Autologous Cord Blood Infusion Is Associated with Motor Improvement in Children with Cerebral Palsy.” In Biology of Blood and Marrow Transplantation, 22:S61–62. Elsevier BV, 2016. https://doi.org/10.1016/j.bbmt.2015.11.354.
    Full Text
  - Sun, Jessica, Jennifer Gilner, Jesse Troy, Barbara Waters-Pick, Kristin Page, Amy Murtha, and Joanne Kurtzberg. “530: Preterm umbilical cord blood is enriched for progenitor cells.” In American Journal of Obstetrics and Gynecology, 214:S286–87. Elsevier BV, 2016. https://doi.org/10.1016/j.ajog.2015.10.574.
    Full Text
  - Sun, Jessica, Mohamad Mikati, Jesse Troy, Kathryn Gustafson, Ryan Simmons, Ricki Goldstein, Jodi Petry, et al. “Autologous Cord Blood Infusion for the Treatment of Brain Injury in Children with Cerebral Palsy.” In Blood, Vol. 126. AMER SOC HEMATOLOGY, 2015.
    Link to Item
  - Shoulars, Kevin, Jesse D. Troy, Tracy Gentry, Pamela Noldner, Kristin Page, Andrew Balber, and Joanne Kurtzberg. “Aldehyde dehydrogenase, but not viability of CD34 cells, predicts potency and engraftment after cord blood transplantation.” In Cytotherapy, 17:S14–S14. Elsevier BV, 2015. https://doi.org/10.1016/j.jcyt.2015.03.330.
    Full Text
  - Shoulars, K., J. D. Troy, T. Gentry, P. Noldner, K. Page, A. Balber, and J. Kurtzberg. “Experience in a public cord blood bank using a segment-based aldehyde dehydrogenase assay as a biomarker for umbilical cord blood potency.” In Cytotherapy, 16:S59–S59. Elsevier BV, 2014. https://doi.org/10.1016/j.jcyt.2014.01.213.
    Full Text
  - Shoulars, Kevin, Jesse D. Troy, Pamela Noldner, Tracy Gentry, Kristin Page, Robert Storms, Andrew E. Balber, and Joanne Kurtzberg. “Experience in a Public Cord Blood Bank Using a Segment-Based Aldehyde Dehydrogenase Assay As a Biomarker for Umbilical Cord Blood Potency.” In Biology of Blood and Marrow Transplantation, 20:S187–88. Elsevier BV, 2014. https://doi.org/10.1016/j.bbmt.2013.12.307.
    Full Text
Teaching & Mentoring
Recent Courses
Advising & Mentoring
- Student:       Julia Messina, MD
  Project Title: Genomic Characterization of Enterococcal Bloodstream Isolates in Hematologic Malignancies
  My Role:       Master's thesis committee member, CRTP program
  
  Student:       Saisha Muniz Alerz, MD
  Project Title: Comparison of Automated and Manual Washing of Umbilical Cord Blood for Hematopoietic Stem Cell
                      Transplantation
  My Role:       Scholarship Oversight Committee (SOC) member, Hematology/Oncology Fellowship Program

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Subject Headings

Selected Grants

Industry Relationships

Selected Publications

Academic Articles

Conference Papers

Recent Courses

Advising & Mentoring