Overview
Dr. Sawyer studies organ boundary communication and non-stem-cell mechanisms of repair in the Fox Lab.
Dr. Sawyer is also dedicated to teaching and mentorship.
Dr. Sawyer is also dedicated to teaching and mentorship.
Current Appointments & Affiliations
Assistant Research Professor of Pharmacology and Cancer Biology
·
2018 - Present
Pharmacology & Cancer Biology,
Basic Science Departments
Recent Publications
Orb2 enables rare-codon-enriched mRNA expression during Drosophila neuron differentiation.
Journal Article Nat Commun · June 20, 2024 Regulation of codon optimality is an increasingly appreciated layer of cell- and tissue-specific protein expression control. Here, we use codon-modified reporters to show that differentiation of Drosophila neural stem cells into neurons enables protein exp ... Full text Link to item CiteDistinct responses to rare codons in select Drosophila tissues.
Journal Article Elife · May 6, 2022 Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression. Here, we use codon-modified reporters to perform an organism-wi ... Full text Link to item CiteAccelerated cell cycles enable organ regeneration under developmental time constraints in the Drosophila hindgut.
Journal Article Dev Cell · July 26, 2021 Individual organ development must be temporally coordinated with development of the rest of the organism. As a result, cell division cycles in a developing organ occur on a relatively fixed timescale. Despite this, many developing organs can regenerate cel ... Full text Link to item CiteRecent Grants
ASPET SURF Institutional Award
Inst. Training Prgm or CMEPrincipal Investigator · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2018 - 2028Amgen Scholars Program at Duke
Inst. Training Prgm or CMECo Investigator · Awarded by Amgen Foundation, Inc. · 2023 - 2026Polyploidy after tissue injury: a Drosophila model
ResearchAssistant Research Professor · Awarded by National Institute of General Medical Sciences · 2016 - 2025View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
2010
Ph.D.