Current Appointments & Affiliations
Visiting Scholar in the Department of Pathology
·
2024 - Present
Pathology,
Clinical Science Departments
Recent Publications
FMNL2/SRC-mediated androgen receptor translocation into the nucleus promotes enzalutamide resistance of prostate cancer.
Journal Article iScience · April 2025 Enzalutamide, a second-generation androgen receptor (AR) antagonist, has represented the association with improved overall survival in men with prostate cancer (PCa). However, PCa patients receiving enzalutamide will eventually develop resistance through v ... Full text CiteMonoacylglycerol lipase blockades the senescence-associated secretory phenotype by interfering with NF-κB activation and promotes docetaxel efficacy in prostate cancer.
Journal Article Oncogene · September 2024 Metabolic reprogramming and cellular senescence greatly contribute to cancer relapse and recurrence. In aging and treated prostate, persistent accumulating senescence-associated secretory phenotype (SASP) of cancer cells often limits the overall survival o ... Full text CiteHOXB3 drives WNT-activation associated progression in castration-resistant prostate cancer.
Journal Article Cell death & disease · March 2023 Enabled resistance or innate insensitiveness to antiandrogen are lethal for castration-resistant prostate cancer (CRPC). Unfortunately, there seems to be little can be done to overcome the antiandrogen resistance because of the largely unknown mechanisms. ... Full text CiteEducation, Training & Certifications
Tianjin Medical University (China) ·
2020
Ph.D.