Jiaoti Huang | Scholars@Duke

Jiaoti Huang
Endowed Department Chair of Pathology

I am a physician-scientist with clinical expertise in the pathologic diagnosis of genitourinary tumors including tumors of the prostate, bladder, kidney and testis. Another area of interest is gynecologic tumors. In my research laboratory we study prostate cancer, focusing on molecular mechanisms of carcinogenesis and tumor progression, as well as biomarkers, imaging and novel therapeutic strategies. In addition to patient care and research, I am also passionate about education. I have trained numerous residents, fellows, graduate students and postdocs.

Current Appointments & Affiliations

Endowed Department Chair of Pathology, Pathology, Clinical Science Departments 2017
Professor of Pathology, Pathology, Clinical Science Departments 2016
Professor of Pharmacology and Cancer Biology, Pharmacology & Cancer Biology, Basic Science Departments 2017
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2016
Chair, Pathology, Clinical Science Departments 2016

Contact Information

Background
Education, Training, & Certifications
- Ph.D., New York University 1991
- M.D., Anhui Medical University (China) 1983
Duke Appointment History
- Instructor, Temporary in the Department of Pathology, Pathology, Clinical Science Departments 2015
Research
Selected Grants
- Histologic and Immunohistochemical Biomarkers for Heavily Treated Metastatic Prostate Cancer awarded by National Institutes of Health 2016 - 2021
- Novel Tumor Suppressive Role of Phosphodiesterases in Prostate Cancer awarded by Department of Defense 2016 - 2019
- A novel strategy to identify prostate cancer biomarkers for patient management awarded by National Institutes of Health 2013 - 2018
- Role of the Stroma in Fibrolamellar Hepatocellular Carcinoma awarded by Fibrolamellar Cancer Foundation 2016 - 2017
- Paired Acquisition In Refractory Prostate Cancer (PAIR): Advancing the Promise of the PCF/SU2C/AACR West Coast Prostate Cancer Dream Team awarded by University of California - San Francisco 2016 - 2017
- : Identification of DNA methylation markers for risk of metastasis in localized prostate cancer awarded by Kaiser Permanente 2016
- Stand Up 2 Cancer West Coast Dream Team Grant awarded by University of San Francisco 2013 - 2016
Publications & Artistic Works
Selected Publications
- Book Sections
  - Koo, J, Filson, CP, Huang, J, and Pantuck, AJ. "Collecting Duct Carcinoma and Renal Medullary Carcinoma." In The Kidney: A Comprehensive Guide to Pathologic Diagnosis and Management, edited by DE Hansel, CJ Kane, GP Paner, and S Chang, 109-123. 2016. (Chapter)
  - Brick, A, Niu, J, Huang, J, and Oh, WK. "Possibility for Platinum Chemotherapy Treatment for HRPC Patients?." In Drug Management of Prostate Cancer, edited by WD Figg, CH Chau, and EJ Small, 153-161. NJ: Humana Press, 2010. (Chapter)
  - Wu, C, Chen, G, Na, Y, Xin, D, Yao, JL, di Xant' Agnese, PA, and Huang, J. "The function of Interleukin-8 in prostate cancer." In Progress in Chemokine Research, edited by WP Links, 149-156. New York: Nova Science Publishers, 2007. (Chapter)
  - Huang, J, Yao, JL, and di Sant'Agnese, PA. "Neuroendocrine Differentiation in Prostate Cancer." In Prostate Cancer: Principles and Practice, edited by R Kirby, AW Partin, M Feneley, and JK Parsons, 143-150. London, UK: Martin Dunitz Ltd (Taylor & Francis Group), 2005. (Chapter)
  - Huang, J, and di Sant' Agnese, PA. "Neuroendocrine Differentiation in Prostate Cancer: An Overview." In Advances in Oncology: The Expanding Role of Octreotide I, edited by SWJ Lamberts and L Dogliotti, 243-262. Bristol, UK: BioScientifica Ltd, 2002. (Chapter)
- Conference Papers
  - Samaratunga, H, Montrironi, R, True, L, Epstein, JI, Griffiths, DF, Humphrey, PA, van der Kwast, T, Wheeler, TM, Srigley, JR, Delahunt, B, Egevad, L, and ISUP Prostate Cancer Group, . "Working group 1: specimen handling." International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Nature Publishing Group, 2011.
- Digital Publications
  - Wagner, DG, and Huang, J. "Small Cell Carcinoma of the Prostate." (April 20, 2009). Link to Item
- Journal Articles
  - Holmes, MG, Foss, E, Joseph, G, Foye, A, Beckett, B, Motamedi, D, Youngren, J, Thomas, GV, Huang, J, Aggarwal, R, Alumkal, JJ, Beer, TM, Small, EJ, and Link, TM. "CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield." Journal of vascular and interventional radiology : JVIR 28, no. 8 (August 2017): 1073-1081.e1. Full Text
  - Holtz, JN, Silverman, RK, Tay, KJ, Browning, JT, Huang, J, Polascik, TJ, and Gupta, RT. "New prostate cancer prognostic grade group (PGG): Can multiparametric MRI (mpMRI) accurately separate patients with low-, intermediate-, and high-grade cancer?." Abdominal radiology (New York) (July 18, 2017). Full Text
  - Chang, E, Jones, TA, Natarajan, S, Sharma, D, Simopoulos, D, Margolis, DJ, Huang, J, Dorey, FJ, and Marks, LS. "Value of Tracking Biopsy in Men Undergoing Active Surveillance of Prostate Cancer." The Journal of urology (July 17, 2017). Full Text
  - Chen, W-Y, Tsai, Y-C, Siu, MK, Yeh, H-L, Chen, C-L, Yin, JJ, Huang, J, and Liu, Y-N. "Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis." Oncogene (July 10, 2017). Full Text
  - Grant, DJ, Chen, Z, Howard, LE, Wiggins, E, De Hoedt, A, Vidal, AC, Carney, ST, Squires, J, Magyar, CE, Huang, J, and Freedland, SJ. "UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression." BMC cancer 17, no. 1 (July 3, 2017): 463-. Full Text
  - Chen, K, Xiao, H, Zeng, J, Yu, G, Zhou, H, Huang, C, Yao, W, Xiao, W, Hu, J, Guan, W, Wu, L, Huang, J, Huang, Q, Xu, H, and Ye, Z. "Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer." Clinical cancer research : an official journal of the American Association for Cancer Research 23, no. 13 (July 2017): 3428-3441. Full Text
  - Jamshidi, N, Margolis, DJ, Raman, S, Huang, J, Reiter, RE, and Kuo, MD. "Multiregional Radiogenomic Assessment of Prostate Microenvironments with Multiparametric MR Imaging and DNA Whole-Exome Sequencing of Prostate Glands with Adenocarcinoma." Radiology 284, no. 1 (July 2017): 109-119. Full Text
  - Park, JW, Lee, JK, Witte, ON, and Huang, J. "FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc (June 16, 2017). Full Text
  - Aggarwal, R, Behr, SC, Paris, PL, Truillet, C, Parker, MFL, Huynh, LT, Wei, J, Hann, B, Youngren, J, Huang, J, Premasekharan, G, Ranatunga, N, Chang, E, Gao, KT, Ryan, CJ, Small, EJ, and Evans, MJ. "Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer." Molecular cancer research : MCR (June 7, 2017). Full Text
  - Hegde, JV, Margolis, DJ, Wang, P-C, Reiter, RE, Huang, J, Steinberg, ML, and Kamrava, M. "Establishing the distribution of satellite lesions in intermediate- and high-risk prostate cancer: implications for focused radiotherapy." Prostate cancer and prostatic diseases 20, no. 2 (June 2017): 241-248. Full Text
  - Tay, KJ, Scheltema, MJ, Ahmed, HU, Barret, E, Coleman, JA, Dominguez-Escrig, J, Ghai, S, Huang, J, Jones, JS, Klotz, LH, Robertson, CN, Sanchez-Salas, R, Scionti, S, Sivaraman, A, de la Rosette, J, and Polascik, TJ. "Patient selection for prostate focal therapy in the era of active surveillance: an International Delphi Consensus Project." Prostate cancer and prostatic diseases (March 28, 2017). Full Text
  - Nassiri, N, Margolis, DJ, Natarajan, S, Sharma, DS, Huang, J, Dorey, FJ, and Marks, LS. "Targeted Biopsy to Detect Gleason Score Upgrading during Active Surveillance for Men with Low versus Intermediate Risk Prostate Cancer." The Journal of urology 197, no. 3 Pt 1 (March 2017): 632-639. Full Text
  - Palapattu, GS, Salami, SS, Cani, AK, Hovelson, DH, Lazo de la Vega, L, Vandenberg, KR, Bratley, JV, Liu, C-J, Kunju, LP, Montgomery, JS, Morgan, TM, Natarajan, S, Huang, J, Tomlins, SA, and Marks, LS. "Molecular Profiling to Determine Clonality of Serial Magnetic Resonance Imaging/Ultrasound Fusion Biopsies from Men on Active Surveillance for Low-Risk Prostate Cancer." Clinical cancer research : an official journal of the American Association for Cancer Research 23, no. 4 (February 2017): 985-991. Full Text
  - Priester, A, Natarajan, S, Khoshnoodi, P, Margolis, DJ, Raman, SS, Reiter, RE, Huang, J, Grundfest, W, and Marks, LS. "Magnetic Resonance Imaging Underestimation of Prostate Cancer Geometry: Use of Patient Specific Molds to Correlate Images with Whole Mount Pathology." The Journal of urology 197, no. 2 (February 2017): 320-326. Full Text
  - Feng, N, Yin, Y, He, Y, and Huang, J. "Alternative Splicing Provides a Novel Molecular Mechanism for Prostatic Small-cell Neuroendocrine Carcinoma." European urology 71, no. 1 (January 2017): 79-80. Full Text
  - Tsai, Y-C, Chen, W-Y, Siu, MK, Tsai, H-Y, Yin, JJ, Huang, J, and Liu, Y-N. "Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6." Cancer letters 384 (January 2017): 1-8. Full Text
  - Yin, Y, Zhang, Q, Zhang, H, He, Y, and Huang, J. "Molecular Signature to Risk-Stratify Prostate Cancer of Intermediate Risk." Clinical cancer research : an official journal of the American Association for Cancer Research 23, no. 1 (January 2017): 6-8. Full Text Open Access Copy
  - Aggarwal, R, Beer, TM, Gleave, M, Stuart, JM, Rettig, M, Evans, CP, Youngren, J, Alumkal, JJ, Huang, J, Thomas, G, Witte, O, and Small, EJ. "Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer: Update on the Stand Up 2 Cancer/Prostate Cancer Foundation-Supported West Coast Prostate Cancer Dream Team." European urology focus 2, no. 5 (December 2016): 469-471. Full Text
  - Wu, M, Ingram, L, Tolosa, EJ, Vera, RE, Li, Q, Kim, S, Ma, Y, Spyropoulos, DD, Beharry, Z, Huang, J, Fernandez-Zapico, ME, and Cai, H. "Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis." The Journal of Biological Chemistry 291, no. 49 (December 2016): 25749-25760. Full Text
  - Yan, Y, Li, Z, Xu, X, Chen, C, Wei, W, Fan, M, Chen, X, Li, JJ, Wang, Y, and Huang, J. "All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy." BMC Complementary and Alternative Medicine 16, no. 1 (December 2016). Full Text
  - Stoyanova, T, Riedinger, M, Lin, S, Faltermeier, CM, Smith, BA, Zhang, KX, Going, CC, Goldstein, AS, Lee, JK, Drake, JM, Rice, MA, Hsu, E-C, Nowroozizadeh, B, Castor, B, Orellana, SY, Blum, SM, Cheng, D, Pienta, KJ, Reiter, RE, Pitteri, SJ, Huang, J, and Witte, ON. "Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer." Proceedings of the National Academy of Sciences of the United States of America 113, no. 42 (October 2016): E6457-E6466. Full Text
  - Drake, JM, Paull, EO, Graham, NA, Lee, JK, Smith, BA, Titz, B, Stoyanova, T, Faltermeier, CM, Uzunangelov, V, Carlin, DE, Fleming, DT, Wong, CK, Newton, Y, Sudha, S, Vashisht, AA, Huang, J, Wohlschlegel, JA, Graeber, TG, Witte, ON, and Stuart, JM. "Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer." Cell 166, no. 4 (August 3, 2016): 1041-1054. Full Text
  - Natarajan, S, Raman, S, Priester, AM, Garritano, J, Margolis, DJA, Lieu, P, Macairan, ML, Huang, J, Grundfest, W, and Marks, LS. "Focal Laser Ablation of Prostate Cancer: Phase I Clinical Trial." The Journal of Urology 196, no. 1 (July 2016): 68-75. Full Text
  - Zhang, H, Prado, K, Zhang, KX, Peek, EM, Lee, J, Wang, X, Huang, J, Li, G, Pellegrini, M, and Chin, AI. "Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance." Clinical Cancer Research (May 17, 2016). Link to Item
  - Felker, ER, Lee-Felker, SA, Feller, J, Margolis, DJ, Lu, DS, Princenthal, R, May, S, Cohen, M, Huang, J, Yoshida, J, Greenwood, B, Kim, HJ, and Raman, SS. "In-bore magnetic resonance-guided transrectal biopsy for the detection of clinically significant prostate cancer." Abdominal Radiology 41, no. 5 (May 2016): 954-962. Full Text
  - Park, JW, Lee, JK, Phillips, JW, Huang, P, Cheng, D, Huang, J, and Witte, ON. "Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay." Proceedings of the National Academy of Sciences of USA 113, no. 16 (April 19, 2016): 4482-4487. Link to Item
  - Park, JW, Lee, JK, Phillips, JW, Huang, P, Cheng, D, Huang, J, and Witte, ON. "Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay." Proceedings of the National Academy of Sciences of the United States of America 113, no. 16 (April 4, 2016): 4482-4487. Full Text
  - Lee, JK, Phillips, JW, Smith, BA, Park, JW, Stoyanova, T, McCaffrey, EF, Baertsch, R, Sokolov, A, Meyerowitz, JG, Mathis, C, Cheng, D, Stuart, JM, Shokat, KM, Gustafson, WC, Huang, J, and Witte, ON. "N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells." Cancer Cell 29, no. 4 (April 2016): 536-547. Full Text
  - Li, W, Cohen, A, Sun, Y, Squires, J, Braas, D, Graeber, TG, Du, L, Li, G, Li, Z, Xu, X, Chen, X, and Huang, J. "The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma." Molecular cancer research : MCR 14, no. 4 (April 2016): 344-353. Full Text
  - Filson, CP, Natarajan, S, Margolis, DJA, Huang, J, Lieu, P, Dorey, FJ, Reiter, RE, and Marks, LS. "Prostate cancer detection with magnetic resonance-ultrasound fusion biopsy: The role of systematic and targeted biopsies." Cancer 122, no. 6 (March 15, 2016): 884-892. Full Text
  - Faltermeier, CM, Drake, JM, Clark, PM, Smith, BA, Zong, Y, Volpe, C, Mathis, C, Morrissey, C, Castor, B, Huang, J, and Witte, ON. "Functional screen identifies kinases driving prostate cancer visceral and bone metastasis." Proceedings of the National Academy of Sciences 113, no. 2 (January 12, 2016): E172-E181. Full Text
  - Kamrava, M, Kishan, AU, Margolis, DJ, Huang, J, Dorey, F, Lieu, P, Kupelian, PA, and Marks, LS. "Multiparametric magnetic resonance imaging for prostate cancer improves Gleason score assessment in favorable risk prostate cancer." Practical Radiation Oncology 5, no. 6 (November 2015): 411-416. Full Text
  - Rakow-Penner, RA, White, NS, Margolis, DJA, Parsons, JK, Schenker-Ahmed, N, Kuperman, JM, Bartsch, H, Choi, HW, Bradley, WG, Shabaik, A, Huang, J, Liss, MA, Marks, L, Kane, CJ, Reiter, RE, Raman, SS, Karow, DS, and Dale, AM. "Prostate diffusion imaging with distortion correction." Magnetic Resonance Imaging 33, no. 9 (November 2015): 1178-1181. Full Text
  - Wang, D, Liu, X, Hsieh, B, Bruce, R, Somlo, G, Huang, J, and Sambucetti, L. "Exploring Glycan Markers for Immunotyping and Precision-targeting of Breast Circulating Tumor Cells." Archives of Medical Research 46, no. 8 (November 2015): 642-650. Full Text
  - Chen, Z, Lan, X, Wu, D, Sunkel, B, Ye, Z, Huang, J, Liu, Z, Clinton, SK, Jin, VX, and Wang, Q. "Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer." Nature Communications 6 (September 16, 2015): 8323-8323. Full Text
  - Chen, J-F, Ho, H, Lichterman, J, Lu, Y-T, Zhang, Y, Garcia, MA, Chen, S-F, Liang, A-J, Hodara, E, Zhau, HE, Hou, S, Ahmed, RS, Luthringer, DJ, Huang, J, Li, K-C, Chung, LWK, Ke, Z, Tseng, H-R, and Posadas, EM. "Subclassification of prostate cancer circulating tumor cells by nuclear size reveals very small nuclear circulating tumor cells in patients with visceral metastases." Cancer 121, no. 18 (September 15, 2015): 3240-3251. Full Text
  - Liu, X, Chen, X, Rycaj, K, Chao, H-P, Deng, Q, Jeter, C, Liu, C, Honorio, S, Li, H, Davis, T, Suraneni, M, Laffin, B, Qin, J, Li, Q, Yang, T, Whitney, P, Shen, J, Huang, J, and Tang, DG. "Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells." Oncotarget 6, no. 27 (September 2, 2015): 23959-23986. Full Text
  - Gan, W, Dai, X, Lunardi, A, Li, Z, Inuzuka, H, Liu, P, Varmeh, S, Zhang, J, Cheng, L, Sun, Y, Asara, JM, Beck, AH, Huang, J, Pandolfi, PP, and Wei, W. "SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression." Molecular Cell 59, no. 6 (September 2015): 917-930. Full Text
  - Scafoglio, C, Hirayama, BA, Kepe, V, Liu, J, Ghezzi, C, Satyamurthy, N, Moatamed, NA, Huang, J, Koepsell, H, Barrio, JR, and Wright, EM. "Functional expression of sodium-glucose transporters in cancer." Proceedings of the National Academy of Sciences 112, no. 30 (July 28, 2015): E4111-E4119. Full Text
  - Tsao, C-K, Gray, KP, Nakabayashi, M, Evan, C, Kantoff, PW, Huang, J, Galsky, MD, Pomerantz, M, and Oh, WK. "Patients with Biopsy Gleason 9 and 10 Prostate Cancer Have Significantly Worse Outcomes Compared to Patients with Gleason 8 Disease." The Journal of Urology 194, no. 1 (July 2015): 91-97. Full Text
  - Hu, C-D, Choo, R, and Huang, J. "Neuroendocrine Differentiation in Prostate Cancer: A Mechanism of Radioresistance and Treatment Failure." Frontiers in Oncology 5 (April 14, 2015). Full Text
  - Peek, EM, Song, W, Zhang, H, Huang, J, and Chin, AI. "Loss of MyD88 leads to more aggressive TRAMP prostate cancer and influences tumor infiltrating lymphocytes." The Prostate 75, no. 5 (April 2015): 463-473. Full Text
  - Escamilla, J, Schokrpur, S, Liu, C, Priceman, SJ, Moughon, D, Jiang, Z, Pouliot, F, Magyar, C, Sung, JL, Xu, J, Deng, G, West, BL, Bollag, G, Fradet, Y, Lacombe, L, Jung, ME, Huang, J, and Wu, L. "CSF1 Receptor Targeting in Prostate Cancer Reverses Macrophage-Mediated Resistance to Androgen Blockade Therapy." Cancer Research 75, no. 6 (March 15, 2015): 950-962. Full Text
  - Le, JD, Tan, N, Shkolyar, E, Lu, DY, Kwan, L, Marks, LS, Huang, J, Margolis, DJA, Raman, SS, and Reiter, RE. "Multifocality and Prostate Cancer Detection by Multiparametric Magnetic Resonance Imaging: Correlation with Whole-mount Histopathology." European Urology 67, no. 3 (March 2015): 569-576. Full Text
  - Li, Z, Sun, Y, Chen, X, Squires, J, Nowroozizadeh, B, Liang, C, and Huang, J. "p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma." Molecular Cancer Research 13, no. 3 (March 1, 2015): 584-591. Full Text
  - Liss, MA, White, NS, Parsons, JK, Schenker-Ahmed, NM, Rakow-Penner, R, Kuperman, JM, Bartsch, H, Choi, HW, Mattrey, RF, Bradley, WG, Shabaik, A, Huang, J, Margolis, DJA, Raman, SS, Marks, LS, Kane, CJ, Reiter, RE, Dale, AM, and Karow, DS. "MRI-Derived Restriction Spectrum Imaging Cellularity Index is Associated with High Grade Prostate Cancer on Radical Prostatectomy Specimens." Frontiers in Oncology 5 (February 17, 2015). Full Text
  - Chen, Z, Lan, X, Thomas-Ahner, JM, Wu, D, Liu, X, Ye, Z, Wang, L, Sunkel, B, Grenade, C, Chen, J, Zynger, DL, Yan, PS, Huang, J, Nephew, KP, Huang, TH-M, Lin, S, Clinton, SK, Li, W, Jin, VX, and Wang, Q. "Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer." The EMBO Journal 34, no. 4 (February 12, 2015): 502-516. Full Text
  - Chang, YS, Chen, WY, Yin, JJ, Tillman, H, Huang, J, and Liu, YN. "EGF receptor promotes prostate cancer bone metastasis by downregulating miR-1 and activating TWIST1." Cancer Research 75, no. 15 (2015): 3077-3086. Link to Item
  - Felker, ER, Wu, J, Natarajan, S, Margolis, DJ, Raman, SS, Huang, J, Dorey, F, and Marks, LS. "Serial MRI in Active Surveillance of Prostate Cancer: Incremental Value." The Journal of Urology 195, no. 5 (2015): 1421-1427. Link to Item
  - Gong, Y, Chippada-Venkata, UD, Galsky, MD, Huang, J, and Oh, MK. "Elevated circulating tissue inhibitor of metalloproteinase 1 (TIMP-1) levels are associated with neuroendocrine differentiation in castration resistant prostate cancer." Prostate 75, no. 6 (2015): 616-627. Link to Item
  - Spradling, K, Khoyilar, C, Abedi, G, Okhumov, Z, Wikenheiser, J, Yoon, R, Huang, J, Youssef, RF, Ghoniem, G, and Landman, J. "Redefining the Autonomic Nerve Distribution of the Urinary Bladder Using Three-Dimensional Image Reconstruction." Journal of Urology 194, no. 6 (2015): 1661-1667.
  - Tan, N, Margolis, DJ, Lu, DY, King, KG, Huang, J, Reiter, RE, and Raman, SS. "Characteristics of Detected and Missed Prostate Cancer Foci on 3-T Multiparametric MRI Using an Endorectal Coil Correlated With Whole-Mount Thin-Section Histopathology." AJR. American journal of roentgenology 205, no. 1 (2015): W87-W92. Link to Item
  - Wang, D, Tang, J, Liu, S, and Huang, J. "Carbohydrate Microarrays Identify Blood Group Precursor Cryptic Epitopes as Potential Immunological Targets of Breast Cancer." Journal of Immunology Research 2015 (2015): 1-9. Full Text
  - Sonn, GA, Filson, CP, Chang, E, Natarajan, S, Margolis, DJ, Macairan, M, Lieu, P, Huang, J, Dorey, FJ, Reiter, RE, and Marks, LS. "Initial experience with electronic tracking of specific tumor sites in men undergoing active surveillance of prostate cancer." Urologic Oncology: Seminars and Original Investigations 32, no. 7 (October 2014): 952-957. Full Text
  - Hu, JC, Chang, E, Natarajan, S, Margolis, DJ, Macairan, M, Lieu, P, Huang, J, Sonn, G, Dorey, FJ, and Marks, LS. "Targeted Prostate Biopsy to Select Men for Active Surveillance: Do the Epstein Criteria Still Apply?." The Journal of Urology 192, no. 2 (August 2014): 385-390. Full Text
  - Beltran, H, Tomlins, S, Aparicio, A, Arora, V, Rickman, D, Ayala, G, Huang, J, True, L, Gleave, ME, Soule, H, Logothetis, C, and Rubin, MA. "Aggressive Variants of Castration-Resistant Prostate Cancer." Clinical Cancer Research 20, no. 11 (June 1, 2014): 2846-2850. Full Text
  - Siu, MK, Abou-Kheir, W, Yin, JJ, Chang, Y-S, Barrett, B, Suau, F, Casey, O, Chen, W-Y, Fang, L, Hynes, P, Hsieh, Y-Y, Liu, Y-N, Huang, J, and Kelly, K. "Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance." Oncotarget 5, no. 11 (June 2014): 3770-3784.
  - Lusch, A, Leary, R, Heidari, E, Liss, MA, Okhunov, Z, Perez-Lanzac De Lorca, A, Huang, J, Wikenheiser, J, and Landman, J. "Intrarenal and Extrarenal Autonomic Nervous System Redefined." The Journal of Urology 191, no. 4 (April 2014): 1060-1065. Full Text
  - Sonn, GA, Chang, E, Natarajan, S, Margolis, DJ, Macairan, M, Lieu, P, Huang, J, Dorey, FJ, Reiter, RE, and Marks, LS. "Value of Targeted Prostate Biopsy Using Magnetic Resonance–Ultrasound Fusion in Men with Prior Negative Biopsy and Elevated Prostate-specific Antigen." European Urology 65, no. 4 (April 2014): 809-815. Full Text
  - Sun, F, Chen, H-G, Li, W, Yang, X, Wang, X, Jiang, R, Guo, Z, Chen, H, Huang, J, Borowsky, AD, and Qiu, Y. "Androgen Receptor Splice Variant AR3 Promotes Prostate Cancer via Modulating Expression of Autocrine/Paracrine Factors." Journal of Biological Chemistry 289, no. 3 (January 17, 2014): 1529-1539. Full Text
  - Chamie, K, Soon, GA, Finley, DS, Tan, N, Margolis, DJ, Raman, SS, Natarajan, S, Huang, J, and Reiter, RE. "RE. The role of magnetic resonance imaging in delineating clinically significant prostate cancer." Urology 83, no. 2 (2014): 369-375.
  - Chen, Y, Nowak, I, Huang, J, Keng, PC, Sun, H, Xu, H, Wei, G, and Lee, SO. "Erk/MAP Kinase Signaling Pathway and Neuroendocrine Differentiation of Non–Small-Cell Lung Cancer." Journal of Thoracic Oncology 9, no. 1 (January 2014): 50-58. Full Text
  - Chin, A, Huang, J, and Wang, J-G. "RARP in high-risk prostate cancer: use of multi-parametric MRI and nerve sparing techniques." Asian Journal of Andrology 16, no. 5 (2014): 715-715. Full Text
  - Drake, JM, and Huang, J. "PIP5K1α inhibition as a therapeutic strategy for prostate cancer." Proceedings of the National Academy of Sciences of USA 111, no. 35 (2014): 12578-12579. Link to Item
  - Drake, JM, and Huang, J. "PIP5K1α inhibition as a therapeutic strategy for prostate cancer." Proceedings of the National Academy of Sciences of USA (2014).
  - Huang, J, Lipianskaya, J, Cohen, A, Hsia, E, Squires, J, Li, Z, Zhang, Y, Li, W, Xu, H, Chen, C, and Chen, X. "Androgen-deprivation therapy-induced aggressive prostate cancer with neuroendocrine differentiation." Asian Journal of Andrology 16, no. 4 (2014): 541-541. Full Text
  - Huang, J, Xu, X, and Lipianskaya, J. "Fasting times in serum PSA assay." Asian Journal of Andrology 16, no. 5 (2014): 786-786. Full Text
  - Kroeger, N, Seligson, DB, Signoretti, S, Yu, H, Magyar, CE, Huang, J, Beldegrum, AS, and Pantuck, AJ. "Poor prognosis and advanced clinicopathological features of clear cell renal cell carcinoma (ccRCC) are associated with cytoplasmic subcellular localisation of Hypoxia inducible factor-2α." European journal of cancer 50, no. 8 (2014): 1531-1540.
  - Le, JD, Huang, J, and Marks, LS. "Targeted prostate biopsy: Value of multi-parametric magnetic resonance imaging in detection of localized cancer." Asian journal of andrology 16, no. 4 (2014): 522-529. Link to Item
  - Le, JD, Stephenson, S, Brugger, M, Lu, DY, Lieu, P, Sonn, GA, Natarajan, S, Dorey, FJ, Huang, J, Margolis, DJ, Reiter, RE, and Marks, LS. "Magnetic resonance imaging-ultrasound fusion biopsy for prediction of final prostate pathology." Journal of Urology 192, no. 5 (2014): 1367-1373.
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  - Deng, X, Liu, H, Huang, J, Cheng, L, Keller, ET, Parsons, SJ, and Hu, C-D. "Ionizing Radiation Induces Prostate Cancer Neuroendocrine Differentiation through Interplay of CREB and ATF2: Implications for Disease Progression." Cancer Research 68, no. 23 (December 1, 2008): 9663-9670. Full Text
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  - Ross, RW, Beer, TM, Jacobus, S, Bubley, GT, Taplin, M-E, Ryan, C, Huang, J, and Oh, WK. "A Phase II study of carboplatin plus docetaxel in men with metastatic hormone refractory prostate cancer who are refractory to docetaxel." Cancer 112 (2008): 521-526.
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  - Wagner, DG, Yao, JL, di Sant'Agnese, PA, Cheng, L, Lopez-Beltran, A, Montironi, R, and Huang, J. "Soft tissue tumors in the prostate." Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 29 (2007): 341-350.
  - Wu, C, and Huang, J. "PI3 kinase-AKT-mTOR pathway is involved in neuroendocrine differentiation of prostate cancer." The Journal of biological chemistry 282, no. 6 (2007): 3571-3583.
  - Huang, J, Yao, JL, di Sant'Agnese, PA, Yang, Q, Bourne, PA, and Na, Y. "Immunohistochemical characterization of neuroendocrine cells in prostate cancer." The Prostate 66, no. 13 (September 15, 2006): 1399-1406. Full Text
  - Johnson, AM, Conover, DL, Huang, J, Messing, EM, Ning, R, O’Connell, MJ, Rossi, MA, Sun, T-T, Wood, RW, Wu, X-R, and Reeder, JE. "Early detection and measurement of urothelial tumors in mice." Urology 67, no. 6 (June 2006): 1309-1314. Full Text
  - Yao, JL, Madeb, R, Bourne, P, Lei, J, Yang, X, Tickoo, S, Liu, Z, Tan, D, Cheng, L, Hatem, F, Huang, J, and Anthony di SantʼAgnese, P. "Small Cell Carcinoma of the Prostate: An Immunohistochemical Study." The American Journal of Surgical Pathology 30, no. 6 (June 2006): 705-712. Full Text
  - Lei, J, Bourne, PA, di Sant'Agnese, PA, and Huang, J. "Cytoplasmic staining of TTF-1 in the differential diagnosis of hepatocellular carcinoma versus cholangiocarcinoma and metastatic carcinoma of the liver." American Journal of Clinical Pathology 125 (2006): 519-525.
  - Markhardt, KB, Rubens, DJ, Huang, J, and Dogra, VS. "Sonographic features of Biliary Hamartomas with histopathological correlation." Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 25 (2006): 1631-1633.
  - Sun, Y, Gao, D, Liu, Y, Huang, J, Lessnick, S, and Tanaka, S. "IGF2 is critical for tumorigenesis by synovial sarcoma oncoprotein SYT-SX1." Oncogene 25 (2006): 1042-1052.
  - Wu, C, Yao, JL, Di Sant'Agnese, PA, Na, Y, and Huang, J. "Neuroendocrine differentiation in prostate cancer." Zhonghua bing li xue za zhi Chinese journal of pathology 35 (2006): 565-567.
  - Wu, C, Zhang, L, Bourne, PA, Reeder, JE, di Sant'Agnese, PA, Yao, JL, Nia, Y, and Huang, J. "Protein tyrosine phosphatase PTP1B is involved in neuroendocrine differentiation of prostate cance." Prostate 66 (2006): 1125-1135.
  - Zang, Z, Rosen, DG, Yao, JL, Huang, J, and Liu, J. "Expression of p14(ARF), p15(INK4b), p16(INK4a), and DCR2 increases during prostate cancer progression." Modern Pathology 19 (2006): 1339-1343.
  - Li, H, Zhang, L, Lou, H, Ding, I, Kim, S, Wang, L, Huang, J, Di Sant’Agnese, PA, and Lei, J-Y. "Overexpression of Decoy Receptor 3 in Precancerous Lesions and Adenocarcinoma of the Esophagus." American Journal of Clinical Pathology 124, no. 2 (August 2005): 282-287. Full Text
  - Li, R, Ni, J, Bourne, PA, Yeh, S, Yao, J, di Sant'Agnese, PA, and Huang, J. "Cell Culture Block Array for Immunocytochemical Study of Protein Expression in Cultured Cells." Applied Immunohistochemistry & Molecular Morphology 13, no. 1 (March 2005): 85-90. Full Text
  - Huang, J, Wu, C, Yao, JL, and di Sant'Agnese, PA. "Neuroendocrine differentiation in prostate cancer." Edited by BQ Wu. Proceedings of the 4th Asian-Pacific International Academy of Pathology Congress (2005): 57-61.
  - Huang, J, Yao, JL, Zhang, L, Bourne, PA, Quinn, AM, di Sant'Agnese, PA, and Reeder, JE. "Differential expression of Interleukin-8 and its receptors in the neuroendocrine and non-neuroendocrine compartments of prostate cancer." American Journal of Pathology 166 (2005): 1807-1815.
  - Hu, Y-C, Yeh, S, Yeh, S-D, Sampson, ER, Huang, J, Li, P, Hsu, C-L, Ting, H-J, Lin, H-K, Wang, L, Kim, E, Ni, J, and Chang, C. "Functional Domain and Motif Analyses of Androgen Receptor Coregulator ARA70 and Its Differential Expression in Prostate Cancer." Journal of Biological Chemistry 279, no. 32 (August 6, 2004): 33438-33446. Full Text
  - Patton, KT, Tretiakova, MS, Yao, JL, Papavero, V, Huo, L, Adley, BP, Wu, G, Huang, J, Pins, MR, Teh, BT, and Yang, XJ. "Expression of RON Proto-oncogene in Renal Oncocytoma and Chromophobe Renal Cell Carcinoma." The American Journal of Surgical Pathology 28, no. 8 (August 2004): 1045-1050. Full Text
  - Li, R, Yao, JL, Bourne, PA, di Sant'agnese, PA, and Huang, J. "Frequent expression of human carcinoma-associated antigen (HCA), a mucin-type glycoprotein, by cells of prostatic carcinom." Archives of Pathology & Laboratory Medicine 128 (2004): 1412-1417.
  - Liang, S, Yao, JL, Bourne, PA, di Sant'Agnese, PA, Huang, J, and Lei, J. "Over-Expression of Human Carcinoma-Associated Antigen in Esophageal Adenocarcinoma and its Precursor Lesions." American Journal of Clinical Pathology 122 (2004): 747-751.
  - Yao, JL, Bourne, PA, Yang, Q, di Sant'Agnese, PA, and Huang, J. "Overexpression of Human Carcinoma-Associated Antigen (HCA) in Urothelial Carcinoma of the Bladder." Archives of Pathology & Laboratory Medicine 128 (2004): 785-787.
  - Chen, TS, McNally, M, Hulbert, W, di Sant'Agnese, PA, and Huang, J. "Renal Oncocytosis Presenting in Childhood: A Case Report." International Journal of Surgical Pathology 11, no. 4 (October 2003): 325-329. Full Text
  - Daiss, J, Carney, J, Cartun, R, Codington, J, Erdrich, C, Hinchman, C, Huang, J, Mauck, J, and Schnipelsky, P. "Human Carcinoma Antigen: A Marker Useful for Discriminating between Benign Prostatic Hyperplasia and Prostate Cancer." Journal of Clinical Ligand Assay 26 (2003): 177-180.
  - Ni, J, Chen, M, Zhang, Y, Li, R, Huang, J, and Yeh, S. "Vitamin E sccinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery." Biochemical and Biophysical Research Communications 300 (2003): 357-363.
  - Huang, J, Behrens, C, Wistuba, II, Gazdar, AF, and Jagirdar, J. "Clonality of combined tumors: A molecular genetic study." Archives of Pathology & Laboratory Medicine 126 (2002): 437-441.
  - Lee, Y-F, Lin, W-J, Huang, J, Messing, EM, Chan, FL, Wilding, G, and Chang, C. "Activation of Mitogen-activated Protein Kinase Pathway by the Antiandrogen Hydroxyflutamide in Androgen Receptor-negative Prostate Cancer Cells." Cancer Research 62 (2002): 6039-6042.
  - Liu, Z, Huang, J, Yan, Z, and Tan, J. "Application of flow cytometry in the diagnosis and differential disgnosis of lymphoma and leukemia." Zhonghua bing li xue za zhi Chinese journal of pathology 31 (2002): 352-353.
  - Huang, J, Behrens, C, Wistuba, I, Gazdar, AF, and Jagirdar, J. "Molecular analysis of synchronous and metachronous tumors of the lung: Impact on management and prognosis." Annals of Diagnostic Pathology 5, no. 6 (December 2001): 321-329. Full Text
  - Gu, M, Shi, W, Huang, J, Barakat, RR, Thaler, HT, and Saigo, PE. "Association between initial diagnostic procedure and hysteroscopy and abnormal peritoneal washings in patients with endometrial carcinoma." Cancer 90, no. 3 (June 25, 2000): 143-147. Full Text
  - SARIC, MUHAMED, APPLEBAUM, ROBERTM, CULLIFORD, ALFREDT, HUANG, JIAOTI, SCHOLES, JOHNV, and KRONZON, ITZHAK. "Massive Atrial Septal Lipomatous Hypertrophy." Echocardiography 16, no. 8 (November 1999): 833-834. Full Text
  - Huang, J, Mohammadi, M, Rodrigues, GA, and Schlessinger, J. "Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis." The Journal of biological chemistry 270 (1995): 5065-5072.
  - Trachman, JD, Huang, J, and Reem, GH. "Activation of human thymocytes induces the phosphorylation of protein tyrosine phosphatase IC." Comptes rendus de l'Académie des Sciences Paris de la vie/Life Sciences 318 (1995): 367-374.
  - Spivak-Kroizman, T, Lemmon, MA, Dikic, I, Ladbury, JE, Pinchasi, D, Huang, J, Jaye, M, Crumley, G, Schlessinger, J, and Lax, I. "Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation." Cell 79, no. 6 (December 1994): 1015-1024. Full Text
  - Huang, J. "Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766." The Journal of biological chemistry 269 (1994): 17056-17061.
  - Vogel, W, Lammers, R, Huang, J, and Ullrich, A. "Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation." Science 259, no. 5101 (March 12, 1993): 1611-1614. Full Text
  - Levy, JB, Canoll, PD, Silvennoinen, O, Barnea, G, Morse, B, Honegger, AM, Huang, J, Cannizzaro, LA, Park, SH, Druck, T, Huebner, K, Barnea, G, Sap, J, and Schlessinger, J. "The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system." The Journal of biological chemistry 268 (1993): 10573-1081.
  - Huang, J, and Schneider, RJ. "Adenovirus inhibition of cellular protein synthesis involves inactivation of cap-binding protein." Cell 65, no. 2 (April 1991): 271-280. Full Text
  - Dolph, PJ, Huang, J, and Schneider, RJ. "Translation by the adenovirus tripartite leader: elements which determine independence from cap-binding protein complex." Journal of virology 64 (1990): 2669-2677.
  - Huang, J, and Schneider, RJ. "Adenovirus inhibition of cellular protein synthesis is prevented by the drug 2-aminopurine." Proceedings of the National Academy of Sciences of the United States of America 87, no. 18 (1990): 7115-7119.
  - Huang, J, and Tang, Z. "Measurement of estrogen receptor in the nuclei of bone marrow cells of male mice after the administration of estrogen." Bulletin of the Academy of Military Medical Sciences 2 (1988): 24-26.

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