Scholars@Duke
Jiaoti Huang

Jiaoti Huang

Johnston-West Distinguished Professor of Pathology
Pathology

Scholarly Works - Other

Supplementary Table S1 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <p>Primary antibodies used for immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB)</p> ... Full text Cite

Supplementary Figure S4 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <p>Figure S4. Quantification of bone mineral density in mouse tibia specimen after treatment for 30 days. Batiraxcept and docetaxel as single agents or in combination increased bone mineral density (BMD) of the tibiae to a similar extent as d ... Full text Cite

Supplementary Figure S3 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <p>Figure S3. Mouse serum PSA after treatment for 30 days. Batiraxcept and docetaxel as single agents or in combination significanty reduced mouse serum PSA detected by ELISA.</p> ... Full text Cite

Supplementary Figure S2 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <p>Figure S2. Batiraxcept and docetaxel alone or in combination significantly inhibited bone tumor growth and metastasis in LuCaP mPCa AC PDX models. A-B, Representative images of Masson-Goldner staining and Ku70 IHC of PDX cells in the tibia ... Full text Cite

Supplementary Figure S1 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <p>Figure S1. The levels of murine serum GAS6 before treatment in the LuCaP 147 PDX model. There were no significant differences in murine serum GAS6 levels among groups detected by ELISA</p> ... Full text Cite

Supplementary Figure S6 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <p>Figure S6. IHC staining (continuing Fig. 6A) demonstrates batiraxcept alone or in combination with docetaxel reduced p-ERK1/2 protein levels compared to vehicle-treated controls in intratibial LuCaP 147CR PDX model while total AKT proteins ... Full text Cite

Supplementary Figure S5 from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <p>Figure S5. Mouse body weight change (%) after treatment for 30 days. None of the treatment groups displayed significant differences in body weight, indicating overall low toxicity from batiraxcept and docetaxel at the doses administered.&l ... Full text Cite

Data from Targeting AXL Inhibits the Growth and Metastasis of Prostate Cancer in Bone

Other · April 1, 2025 <div>AbstractPurpose:<p>After failing primary and secondary hormonal therapy, castration-resistant and neuroendocrine prostate cancer metastatic to the bone is invariably lethal, although treatment with docetaxel and carboplatin can mod ... Full text Cite