Scholars@Duke
John Musgrove Jr.

John Musgrove Jr.

Assistant Professor of Medicine
Medicine, Nephrology

Scholarly Works - Journal articles

De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis.

Journal article Am J Hum Genet · February 4, 2021 Focal segmental glomerulosclerosis (FSGS) is the main pathology underlying steroid-resistant nephrotic syndrome (SRNS) and a leading cause of chronic kidney disease. Monogenic forms of pediatric SRNS are predominantly caused by recessive mutations, while t ... Full text Link to item Cite

FGFR4 does not contribute to progression of chronic kidney disease.

Journal article Sci Rep · October 1, 2019 In chronic kidney disease (CKD), elevated serum levels of the phosphate regulating hormone fibroblast growth factor (FGF) 23 have emerged as powerful risk factors for cardiovascular disease and death. Mechanistically, FGF23 can bind and activate fibroblast ... Full text Link to item Cite