Overview
Dr. Joan Mary Jasien is a Med‑Peds–trained child neurologist and neurodevelopmental disabilities specialist with board certification in Internal Medicine, Pediatrics, and Neurology. She completed her Med‑Peds residency followed by fellowship training in Child Neurology and Neurodevelopmental Disabilities before joining Duke University Medical Center.
She co‑founded and co‑directs the Children’s Cerebral Palsy–Related Conditions Clinic, the Adults with Cerebral Palsy–Related Conditions Clinic, and the Adults with Spina Bifida Clinic, and also serves as Co‑Director of the Children’s Spina Bifida Clinic. Together, these four programs form Duke’s multidisciplinary clinics for children and adults with spina bifida and cerebral palsy–related conditions. Her clinical expertise focuses on hyperkinetic movements and hypertonia in individuals with cerebral palsy and related conditions, as well as the overall cognition and functioning of individuals with spina bifida and cerebral palsy and related conditions.
Dr. Jasien’s research centers on neurological aging in individuals with spina bifida and on community engagement in research, with the goal of improving long‑term health outcomes across the lifespan.
Current Appointments & Affiliations
Recent Publications
Deep Brain Stimulation for Dystonia and Epilepsy in Alternating Hemiplegia of Childhood.
Journal Article Mov Disord · April 19, 2026 Full text Link to item CiteNatural History of Alternating Hemiplegia of Childhood: Vulnerabilities in Early Childhood and Predictive Factors for Long‐Term Outcomes
Journal Article Annals of the Child Neurology Society · December 2025 ABSTRACTObjective The natural history of the most common ATP1A3 Full text CiteSequencing Analysis Demonstrates That a Complex Genetic Architecture Contributes to Risk for Spina Bifida.
Journal Article Birth Defects Res · October 2025 BACKGROUND: Spina bifida (SB), a common neural tube defects (NTDs), has a complex genetic architecture that remains incompletely understood. Although prior studies have identified rare, deleterious single nucleotide variants (SNVs) in SB, broader contribut ... Full text Link to item CiteRecent Grants
Guanfacine for Hyperactivity in Children with Down Syndrome
ResearchPrincipal Investigator · Awarded by DCRI-Duke-Site · 2024 - 2026View All Grants
Recent Artistic Works
Educational Videos Increase Study Team Members’ Comfort With Enhancing Trial Participation of Children with Down Syndrome
Video Recording Research September 8, 2023View All Artistic Works