https://orcid.org/0000-0003-1311-5416
Current Duke Appointments & Affiliations
Clinical Faculty in the Department of Medicine
·
2025 - Present
Medicine, Medical Oncology,
Medicine
Recent Scholarly Works
Clinical and genomic determinants of extraordinary response and resistance to androgen receptor pathway inhibitors in men with metastatic androgen pathway modulator sensitive (APMS) prostate cancer.
Journal article Prostate Cancer Prostatic Dis · August 5, 2026 BACKGROUND: Identifying clinical and genomic predictors of response to androgen deprivation therapy (ADT) and androgen receptor pathway inhibitors (ARPI) for metastatic androgen pathway modulator sensitive (APMS) prostate cancer is essential for improving ... Full text Link to item CiteSPOP Mutations in Veterans With Prostate Cancer and Outcomes With Doublet and Triplet Therapy in De Novo Metastatic Hormone Sensitive Prostate Cancer.
Journal article Prostate · June 2026 BACKGROUND: Inactivating missense mutations in the tumor suppressor gene speckle-type pox virus and zinc finger protein (SPOP) occur in 5%-15% of men with prostate cancer (PC). SPOP mutations increase androgen receptor-mediated transcription and enhance se ... Full text Link to item CiteOutcomes for Patients With SPOP Mutated Castration-Resistant Prostate Cancer (CRPC) Treated With an Androgen Receptor Pathway Inhibitor (ARPI).
Journal article Clin Genitourin Cancer · March 2026 INTRODUCTION: Inactivating missense mutations in the SPOP gene increase the transcriptional activity of the androgen receptor and sensitivity to hormonal therapies in patients with hormone sensitive prostate cancer (HSPC). However, the relationship of SPOP ... Full text Link to item CiteEducation
Cornell University, Weill Medical College ·
2019
M.D.