Scholarly Works - Book sections
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January 1, 2025
Cancer is among the leading causes of death in most countries, including the United States. Genetics and exposure to carcinogens in the environment each play major roles in causing cancer. In this chapter, we discuss the interplay between the biology of ca ...
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January 1, 2025
Mitochondria are essential subcellular organelles, generating >90% of the cellular ATP needed to meet the functional needs of the organism and carrying out a multitude of other essential functions. Mitochondria harbor an essential, high copy number, small ...
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January 1, 2024
The purpose of Chapter 4 is to describe a particular set of phenomena that collectively comprise an important mechanism of chemical toxicity and cellular defense. These phenomena, referred to as redox stress, encompass oxidative and reductive stress and ap ...
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February 21, 2018
This chapter summarizes some of what is known about environmental mitotoxicants and mechanisms of pollutant-induced mitochondrial dysfunction. It outlines some of the challenges and factors that complicate the research community's ability, and discusses th ...
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