Scholarly Works - Preprints
Preprint
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2026
Summary While a growing number of studies have linked environmental exposures and Parkinson’s disease (PD) 1–3 , the impact of many pesticides remains understudied 4,5 ; for example, neonicotinoids are the most used insecticides in the world, b ...
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Preprint
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May 3, 2025
Cell invasion through basement membrane (BM) is energetically intensive, and how an invading cell produces high ATP levels to power invasion is understudied. By generating 20 endogenously tagged mitochondrial proteins, we identified a specialized mitochond ...
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Preprint
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April 9, 2025
The quality of mitochondria inherited from the oocyte determines embryonic viability, metabolic health throughout progeny lifetime, and future generation endurance. High levels of endogenous reactive oxygen species and exogenous toxicants are threats to mi ...
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Preprint
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February 3, 2025
The quality of inherited mitochondria determines embryonic viability 1 , metabolic health during adulthood and future generation endurance. The oocyte is the source of all zygotic mitochondria 2 , and mitochondrial health is under strict developmental regu ...
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Preprint
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2023
Background Diets high in saturated fat and sugar, termed ‘western diets’, have been associated with several negative health outcomes, including increased risk for neurodegenerative disease. Parkinson’s Disease (PD) is the second most prevalent ne ...
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Preprint
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2023
Gulf War Illness (GWI) is a major health problem for approximately 250,000 Gulf War (GW) veterans, but the etiology of GWI is unclear. We hypothesized that mitochondrial dysfunction is an important contributor to GWI, based on the similarity of some GWI sy ...
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