Overview
I am an Adjunct Professor of Medicine, Pathology, and Global Health. My work with Duke University is primarily based in northern Tanzania where I am former Site Leader and current Principal Investigator on projects linked to Duke University’s collaborative research program at Kilimanjaro Christian Medical Centre. I oversee the design and implementation of research studies on infectious diseases, particularly febrile illness, invasive bacterial disease, zoonotic infections, and infectious diseases diagnostics. In addition, I am Professor of Medicine, Pathology, and Global Health at the University of Otago and a medical epidemiologist with the US Centers for Disease Control and Prevention (CDC). My CDC work focuses on non-malaria febrile illness.
Current Duke Appointments & Affiliations
Adjunct Professor in the Department of Medicine
·
2011 - Present
Medicine, Infectious Diseases,
Medicine
Adjunct Professor in the Department of Pathology
·
2011 - Present
Pathology,
Clinical Science Departments
Adjunct Professor of Global Health
·
2015 - Present
Duke Global Health Institute,
University Institutes and Centers
Recent Scholarly Works
The host transcriptional response to real-world cryptococcosis in the setting of advanced HIV disease defines dysregulated immune responses that underlie increased vulnerability to infection.
Journal article J Infect Dis · October 1, 2026 BACKGROUND: Cryptococcus causes life-threatening infections; however, immune programs driving pathogenesis of these infections in the human host remain incompletely described. We leveraged whole-blood transcriptomic analysis to define distinct, conserved e ... Full text Link to item CiteDerivation and validation of clinical subphenotypes of adult sepsis in Africa: A latent class analysis of infection site and organ dysfunction.
Journal article medRxiv · September 8, 2026 OBJECTIVE: Sepsis is a heterogeneous syndrome characterized by substantial variation in infection source, organ dysfunction, and clinical outcomes, and a disproportionate burden in Africa. We aimed to derive and externally validate clinical subphenotypes a ... Full text Link to item CiteStrengthening the Reporting of Observational Studies in Epidemiology Enhanced Prevalence and Incidence Criteria (STROBE EPIC): An Extension of the STROBE Statement.
Journal article Ann Intern Med · September 2026 Prevalence and incidence are fundamental metrics with numerous applications in epidemiology. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guideline lacks specific items for reporting studies of disease prevalence or inc ... Full text Link to item CiteRecent Grants
Viral Zoonoses and Severe Febrile Illness in Northern Tanzania (K23)
ResearchMentor · Awarded by National Institutes of Health · 2016 - 2021Investigating Febrile Deaths in Tanzania (INDITe)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2021One Health Innovation Fellowships for Zoonotic Disease Research in Mongolia
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2013 - 2019View All Grants
Education
University of Otago (New Zealand) ·
1993
M.B.B.Ch.