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John Andrew Crump

Adjunct Professor in the Department of Medicine
Medicine, Infectious Diseases
Box 90519, Duke Global Health Institute, Durham, NC 27708
Trent Hall, Room 115, Durham, NC 27708

Featured Works


Invasive non-Typhi Salmonella disease in Africa.

Journal article Clin Infect Dis · August 15, 2009 Featured Publication Invasive non-Typhi Salmonella is endemic to sub-Saharan Africa, where it is a leading cause of bloodstream infection. Some host risk factors have been established, but little is known about environmental reservoirs and predominant modes of transmission, so ... Full text Link to item Cite

Effect of trimethoprim-sulfamethoxazole prophylaxis on antimicrobial resistance of fecal Escherichia coli in HIV-infected patients in Tanzania.

Journal article J Acquir Immune Defic Syndr · April 15, 2008 Featured Publication BACKGROUND: Trimethoprim-sulfamethoxazole (SXT) reduces morbidity and mortality among HIV-infected persons in Africa, but its impact on antimicrobial resistance is of concern. METHODS: HIV-uninfected (group A), HIV-infected but not requiring SXT (group B), ... Full text Link to item Cite

Clinical response and outcome of infection with Salmonella enterica serotype Typhi with decreased susceptibility to fluoroquinolones: a United States foodnet multicenter retrospective cohort study.

Journal article Antimicrob Agents Chemother · April 2008 Featured Publication Patients with typhoid fever due to Salmonella enterica serotype Typhi strains for which fluoroquinolones MICs are elevated yet that are classified as susceptible by the current interpretive criteria of the Clinical and Laboratory Standards Institute may no ... Full text Link to item Cite

Predictors of incomplete adherence, virologic failure, and antiviral drug resistance among HIV-infected adults receiving antiretroviral therapy in Tanzania.

Journal article Clin Infect Dis · December 1, 2007 Featured Publication BACKGROUND: Access to antiretroviral therapy is rapidly expanding in sub-Saharan Africa. Identifying the predictors of incomplete adherence, virologic failure, and antiviral drug resistance is essential to achieving long-term success. METHODS: A total of 1 ... Full text Link to item Cite

Cost-effectiveness of free HIV voluntary counseling and testing through a community-based AIDS service organization in Northern Tanzania.

Journal article Am J Public Health · January 2006 Featured Publication OBJECTIVES: We evaluated the cost-effectiveness of fee-based and free testing strategies at an HIV voluntary counseling and testing (VCT) program integrated into a community-based AIDS service organization in Moshi, Tanzania. METHODS: We waived the usual f ... Full text Link to item Cite

Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: cluster randomised controlled trial.

Journal article BMJ · September 3, 2005 Featured Publication OBJECTIVE: To compare the effect on prevalence of diarrhoea and mortality of household based treatment of drinking water with flocculant-disinfectant, sodium hypochlorite, and standard practices in areas with turbid water source in Africa. DESIGN: Cluster ... Full text Link to item Cite

The global burden of typhoid fever.

Journal article Bull World Health Organ · May 2004 Featured Publication OBJECTIVE: To use new data to make a revised estimate of the global burden of typhoid fever, an accurate understanding of which is necessary to guide public health decisions for disease control and prevention efforts. METHODS: Population-based studies usin ... Link to item Cite

Two decades of disseminated tuberculosis at a university medical center: the expanding role of mycobacterial blood culture.

Journal article Clin Infect Dis · October 15, 2003 Featured Publication We describe the clinical presentation, predisposing conditions, diagnostic approach, and outcome for 52 patients with disseminated tuberculosis who presented at Duke University Medical Center (Durham, NC) from 1980 through 1999. The mean age of the patient ... Full text Link to item Cite