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John Andrew Crump

Adjunct Professor in the Department of Medicine
Medicine, Infectious Diseases
Box 90519, Duke Global Health Institute, Durham, NC 27708
Trent Hall, Room 115, Durham, NC 27708

Scholarly Works - Preprints


Mass spectrometry-based quantification of proteins and post-translational modifications in dried blood: longitudinal sampling of patients with sepsis in Tanzania.

Preprint · April 28, 2025 The proteomic analysis of blood is routine for disease phenotyping and biomarker development. Whole blood is commonly separated into soluble and cellular fractions. However, this can introduce pre-analytical variability; and analysis of a single component ... Full text Link to item Cite

Mortality, morbidity, and post-operative complications of typhoid intestinal perforations: global systematic review and meta-analysis

Preprint · 2024 Background TIP is a serious and life-threatening complication of typhoid fever that requires emergency surgery and an important driver of typhoid burden. We aimed to review global studies reporting on mortality, morbidity, and post-operative comp ... Full text Cite

Prevalence and distribution of non-typhoidal Salmonella enterica serogroups and serovars isolated from normally sterile sites: a global systematic review

Preprint · 2023 Summary To inform vaccine development strategies, we aimed to systematically review evidence on the prevalence and distribution of non-typhoidal Salmonella enterica serogroups and serovars. We searched four databases from inception through 4 Jun ... Full text Cite

Global diversity and antimicrobial resistance of typhoid fever pathogens: insights from 13,000SalmonellaTyphi genomes

Preprint · 2022 The Global Typhoid Genomics Consortium was established to bring together the typhoid research community to aggregate and analyse Salmonella enterica serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks twenty-one ye ... Full text Cite

Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania

Preprint · 2021 Livestock abortion is an important cause of productivity losses worldwide and many infectious causes of abortion are zoonotic pathogens that impact on human health. Little is known about the relative importance of infectious causes of livestock abortion in ... Full text Cite