John Hunter Peel Alexander

Conference J Am Heart Assoc · January 3, 2023 Background The effectiveness of vascular closure devices (VCDs) to reduce bleeding after transfemoral percutaneous coronary intervention remains unsettled. Methods and Results Participants in the REGULATE-PCI (Effect of the REG1 anticoagulation system vers ... Full text Link to item Cite

Reduced versus Standard Dose Apixaban in Patients With Atrial Fibrillation and Acute Coronary Syndrome and/or Undergoing Percutaneous Coronary Intervention: Insights From the AUGUSTUS Trial

Conference CIRCULATION · November 8, 2022 Link to item Cite

TCT-1 Bleeding in Patients With Atrial Fibrillation and Acute Coronary Syndrome or PCI Treated With Antithrombotic Therapy: Insights From the AUGUSTUS Trial

Conference Journal of the American College of Cardiology · September 2022 Full text Cite

Efficacy and Safety of an External Support Device for Saphenous Vein Coronary Bypass Grafts: The VEST Trial

Conference CIRCULATION · December 21, 2021 Link to item Cite

Relationship Between Body Weight and Pharmacokinetics of Apixaban in Patients With Atrial Fibrillation: Insights from the ARISTOTLE Trial

Conference CIRCULATION · November 16, 2021 Link to item Cite

EFFECT OF APIXABAN VERSUS VITAMIN K ANTAGONIST AND ASPIRIN VERSUS PLACEBO ON DAYS ALIVE AND OUT OF HOSPITAL IN THE AUGUSTUS RANDOMIZED CONTROLLED TRIAL

Conference JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · May 11, 2021 Link to item Cite

Prior Oral Anticoagulant Status and Outcomes in Patients With Atrial Fibrillation With an Acute Coronary Syndrome and/or Undergoing Percutaneous Coronary Intervention: Insights From the Augustus Trial

Conference CIRCULATION · November 17, 2020 Link to item Cite

Safety and efficacy of antithrombotic therapy according to stroke and bleeding risk in patients with atrial fibrillation and acute coronary syndrome or PCI: insights from AUGUSTUS

Conference EUROPEAN HEART JOURNAL · November 2020 Link to item Cite

EFFECT OF LONGITUDINAL STRAIN ON CLINICAL AND ECHOCARDIOGRAPHIC OUTCOMES AFTER CARDIAC SURGERY FOR MODERATE ISCHEMIC MITRAL REGURGITATION

Conference JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · March 24, 2020 Link to item Cite

Stent Thrombosis After Percutaneous Coronary Intervention Among Patients With Atrial Fibrillation Treated With Apixaban or Aspirin: Insights From the AUGUSTUS Trial

Conference CIRCULATION · December 17, 2019 Link to item Cite

Postoperative Acute Kidney Injury is Common and Associated With Increased Mortality in Patients Undergoing Cardiac Surgery: Insights From the LEVO-CTS Trial

Conference CIRCULATION · November 19, 2019 Link to item Cite

Apixaban 2.5 mg twice daily is effective and safe for patients with atrial fibrillation and combinations of advanced age, low body weight, and elevated creatinine: insights from ARISTOTLE

Conference EUROPEAN HEART JOURNAL · October 1, 2019 Link to item Cite

Impact of different estimates of renal function on cardiovascular mortality and major bleeding in patients with atrial fibrillation on oral anticoagulation

Conference EUROPEAN HEART JOURNAL · October 1, 2019 Link to item Cite

TRANSFUSIONS, WITH OR WITHOUT CONCOMITANT BLEEDING, ARE ASSOCIATED WITH HIGH SHORT-TERM MORTALITY IN PATIENTS WITH ATRIAL FIBRILLATION TREATED WITH ORAL ANTICOAGULATION

Conference Journal of the American College of Cardiology · March 2019 Full text Cite

Nsaid Use is Associated With Worse Outcomes but Similar Benefits of Apixaban Over Warfarin in Patients With Atrial Fibrillation: Results From the ARISTOTLE Trial

Conference CIRCULATION · November 6, 2018 Link to item Cite

GDF-15 is Associated With Major Bleeding and Death Independent of Geographic Regions in Patients With Atrial Fibrillation

Conference CIRCULATION · November 6, 2018 Link to item Cite

The Biomarker-Based ABC-Bleeding Risk Score Refines the Risk of Bleeding in Patients With Atrial Fibrillation With Combined Aspirin and Anticoagulation Therapy

Conference CIRCULATION · November 6, 2018 Link to item Cite

Faster heart rate is associated with significantly higher risk of death and hospitalization due to heart failure in patients with persistent or permanent atrial fibrillation: insights from ARISTOTLE

Conference EUROPEAN HEART JOURNAL · August 1, 2018 Link to item Cite

Cardiac troponin T concentrations are lower in women than men with atrial fibrillation but have similar prognostic value regardless of sex - insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2018 Link to item Cite

Elevated biomarkers are associated with increased risk of death and heart failure hospitalization in patients with atrial fibrillation: insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2018 Link to item Cite

Novel prognostic biomarkers identified by proximity extension assay are associated with major bleeding in patients with atrial fibrillation on oral anticoagulation: insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2018 Link to item Cite

THE SAFETY AND TOLERABILITY OF MULTIPLE DOSE ADMINISTRATION OF CSL112, AN INTRAVENOUS FORMULATION OF PLASMA-DERIVED APOA-I, AMONG SUBJECTS WITH MODERATE RENAL IMPAIRMENT AFTER ACUTE MYOCARDIAL INFARCTION

Conference Journal of the American College of Cardiology · March 2018 Full text Cite

Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial.

Conference Am J Med · December 2017 BACKGROUND: Cancer is associated with a prothrombotic state and increases the risk of thrombotic events in patients with atrial fibrillation. We described the clinical characteristics and outcomes and assessed the safety and efficacy of apixaban versus war ... Full text Link to item Cite

Incidence, Timing, and Type of First and Recurrent Ischemic Events in Patients With and Without Peripheral Artery Disease After an Acute Coronary Syndrome

Conference CIRCULATION · November 14, 2017 Link to item Cite

INR prior to bleeding is below 3.0 most of the time in patients with atrial fibrillation using warfarin

Conference EUROPEAN HEART JOURNAL · August 1, 2017 Link to item Cite

Clinical outcomes in patients with atrial fibrillation and echocardiographic risk factors for stroke anticoagulated with apixaban or warfarin

Conference EUROPEAN HEART JOURNAL · August 1, 2017 Link to item Cite

Serial IL-6 levels and risk of death in anticoagulated patients with atrial fibrillation: Insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2017 Link to item Cite

A novel biomarker-based risk score to predict death in patients with atrial fibrillation: Insights from the ARISTOTLE and RE-LY trials

Conference EUROPEAN HEART JOURNAL · August 1, 2017 Link to item Cite

Low apolipoprotein a1 is significantly associated with decreased risk of cardiovascular events in anticoagulated patients with atrial fibrillation: insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2017 Link to item Cite

CARMELINA (R) Trial Baseline Characteristics: A Cardiovascular and Renal Microvascular Outcome Trial with Linagliptin in Patients with Type 2 Diabetes at High Vascular Risk

Conference DIABETES · June 1, 2017 Link to item Cite

CLOPIDOGREL IS NOT COMMONLY USED BUT ASSOCIATED WITH LESS RE-HOSPITALIZATION IN PATIENTS WITH PERIOPERATIVE MYOCARDIAL INFARCTION FOLLOWING CABG SURGERY

Conference Journal of the American College of Cardiology · March 2017 Full text Cite

AORTIC STENOSIS, BUT NOT MITRAL OR AORTIC REGURGITATION, IS ASSOCIATED WITH ADVERSE OUTCOMES WITH ATRIAL FIBRILLATION: RESULTS FROM THE ARISTOTLE TRIAL

Conference Journal of the American College of Cardiology · March 2017 Full text Cite

The Safety and Tolerability of CSL112, a Reconstituted, Infusible, Human APOA-I, After Acute Myocardial Infarction - The APOA-I Event Reduction in Ischemic Syndromes I (AEGIS-I) Trial

Conference CIRCULATION · December 20, 2016 Link to item Cite

Biomarkers Predict Cause of Death More Accurately Than Clinical Variables in Patients With Atrial Fibrillation on Oral Anticoagulation Results From the ARISTOTLE Trial

Conference CIRCULATION · November 11, 2016 Link to item Cite

Percutaneous Coronary Intervention and Antiplatelet Therapy on Apixaban or Warfarin: Insights From the ARISTOTLE Trial

Conference CIRCULATION · November 11, 2016 Link to item Cite

Patients with atrial fibrillation and history of falls are at high risk for bleeding but have less bleeding with apixaban than warfarin: results from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2016 Link to item Cite

APIXABAN VERSUS WARFARIN FOR PATIENTS WITH RECENT ONSET ATRIAL FIBRILLATION: INSIGHTS FROM THE ARISTOTLE TRIAL

Conference Journal of the American College of Cardiology · April 2016 Full text Cite

Adverse Event Reporting in > 48,000 Participants in Four Acute Coronary Syndrome Trials

Conference CIRCULATION · November 10, 2015 Link to item Cite

Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial.

Conference Circulation · August 25, 2015 BACKGROUND: Apixaban is approved for the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. However, the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial inc ... Full text Link to item Cite

External validation of the biomarker-based ABC-stroke risk score for atrial fibrillation

Conference EUROPEAN HEART JOURNAL · August 1, 2015 Link to item Cite

Efficacy and safety of apixaban compared with warfarin in relation to renal function over time in patients with atrial fibrillation: Insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2015 Link to item Cite

Digoxin use is associated with higher mortality among patients with atrial fibrillation with and without heart failure: insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2015 Link to item Cite

Less non-major bleeding with apixaban versus warfarin among patients with atrial fibrillation: insights from the ARISTOTLE trial

Conference EUROPEAN HEART JOURNAL · August 1, 2015 Link to item Cite

Management and clinical consequences of major bleeding in high-risk patients following an acute coronary syndrome. Is aspirin the problem? Insights from the APPRAISE-2 trial

Conference EUROPEAN HEART JOURNAL · August 1, 2015 Link to item Cite

APIXABAN FOLLOWING ACUTE CORONARY SYNDROMES AMONG PATIENTS WITH PRIOR STROKE: INSIGHTS FROM THE APPRAISE-2 TRIAL

Conference Journal of the American College of Cardiology · March 2015 Full text Cite

The Surgical Treatment of Moderate Ischemic Mitral Regurgitation: A Randomized Clinical Trial From The Cardiothoracic Surgical Trials Network

Conference CIRCULATION · December 2, 2014 Link to item Cite

The Cost-Effectiveness of Apixaban versus Warfarin in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Study Group

Conference CIRCULATION · November 25, 2014 Link to item Cite

Does Repeat Measurement of High Sensitivity Troponin I Improve Prediction of Cardiovascular Events in Atrial Fibrillation?

Conference CIRCULATION · November 25, 2014 Link to item Cite

Single Measurement of GDF-15 Provides Reliable Prognostication of Stroke and Major Bleeding in Atrial Fibrillation

Conference CIRCULATION · November 25, 2014 Link to item Cite

Predictors of and clinical outcomes after internal mammary artery graft failure: insights from the PREVENT-IV trial

Conference EUROPEAN HEART JOURNAL · September 1, 2014 Link to item Cite

A new biomarker based risk score for predicting major bleeding in atrial fibrillation - the ABC (age, biomarkers, current disease) risk score

Conference EUROPEAN HEART JOURNAL · September 1, 2014 Link to item Cite

APIXABAN COMPARED WITH WARFARIN IN PATIENTS WITH DIABETES AND NONVALVULAR ATRIAL FIBRILLATION IN THE ARISTOTLE TRIAL

Conference Journal of the American College of Cardiology · April 2014 Full text Cite

POORLY CONTROLLED BLOOD PRESSURE IS INDEPENDENTLY ASSOCIATED WITH A 50% HIGHER RISK OF STROKE OR SYSTEMIC EMBOLISM IN PATIENTS WITH ATRIAL FIBRILLATION: RESULTS FROM THE ARISTOTLE TRIAL

Conference Journal of the American College of Cardiology · April 2014 Full text Cite

High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin.

Conference J Am Coll Cardiol · January 7, 2014 OBJECTIVES: The aim of this study was to evaluate the prognostic value of high-sensitivity troponin T (hs-TnT) in addition to clinical risk factors and the CHA2DS2VASc (congestive heart failure, hypertension, 75 years of age and older, diabetes mellitus, p ... Full text Link to item Cite

Preservation Solutions, Patency, and Outcomes After Coronary Bypass Surgery

Conference CIRCULATION · November 26, 2013 Link to item Cite

Inpatient and Outpatient Resource Utilization in the Evaluation and Management of Patients With Aortic Stenosis Being Considered for Transcatheter Aortic Valve Replacement (TAVR)

Conference CIRCULATION · November 26, 2013 Link to item Cite

Efficacy and Safety of Apixaban in Patients With Atrial Fibrillation According to Sex: Results From the ARISTOTLE Trial

Conference CIRCULATION · November 26, 2013 Link to item Cite