Scholars@Duke
John Lynch Lyles

John Lynch Lyles

Associate Professor of Pediatrics
Pediatrics, Gastroenterology, Hepatology and Nutrition

Scholarly Works

Simultaneous caustic ingestion in siblings with divergent treatment and the consequences of health inequity.

Journal article JPGN Rep · May 2026 Accidental caustic ingestions are uncommon but can lead to serious esophageal injury. Clinicians may lack experience grading mucosal findings, creating circumstances for treatment misalignment because management recommendations depend on severity. Regardle ... Full text Link to item Cite

Internet Dietary Guidance for Pediatric Inflammatory Bowel Disease: A Quality and Readability Crisis.

Journal article Cureus · January 2026 BACKGROUND: Diet and nutritional therapy are treatment options for children with inflammatory bowel disease (IBD). Parents of children with medical conditions often turn to the internet for medical guidance. However, the quality and readability of internet ... Full text Link to item Cite

Rethinking hyperbilirubinemia: Gilbert syndrome in children with cystic fibrosis, a case report.

Journal article Respir Med Case Rep · 2025 Cystic Fibrosis leads to liver complications, including cystic fibrosis liver disease but hyperbilirubinemia in CF patients on CFTR modulators is less understood. This article describes two pediatric CF patients on Elexacaftor/Tezacaftor/Ivacaftor therapy ... Full text Link to item Cite

Manometric findings in children with eosinophilic esophagitis and persistent post-remission dysphagia.

Journal article JPGN Rep · August 2024 OBJECTIVES: Dysphagia is a frequent symptom of active eosinophilic esophagitis (EoE), but at times it persists despite attaining histologic healing and lack of fibro-stenotic changes. We aimed to describe the manometric findings in this subset of patients. ... Full text Link to item Cite

Cognitive Bias in an Infant with Constipation

Journal article JOURNAL OF PEDIATRICS · July 2024 Full text Link to item Cite

Pediatric Gastrointestinal and Liver Disorders

Book section · January 31, 2023 The second volume continues with psychological and behavioral developments which contain topics on emotion, mindfulness, stress, depression, coping skills, cognitive developments, decision-making and trauma. ... Cite

Neurologic Complications due to Severe Micronutrient Deficiencies in an American Adolescent.

Journal article Nutr Clin Pract · October 2021 Micronutrient deficiencies are a major global health problem but are less common in developed nations. If left unidentified and untreated, micronutrient deficiencies can lead to serious, sometimes irreversible, sequelae such as with vitamin A deficiency an ... Full text Link to item Cite

Effect of a Practice-wide Anti-TNF Proactive Therapeutic Drug Monitoring Program on Outcomes in Pediatric Patients with Inflammatory Bowel Disease.

Journal article Inflammatory bowel diseases · March 2021 BackgroundReports on the feasibility and effectiveness of translating proactive, antitumor necrosis factor (TNF) therapeutic drug monitoring (TDM) for inflammatory bowel disease into practice-wide quality improvement (QI) are lacking. We aimed to ... Full text Cite

50 Years Ago in T J P

Journal article The Journal of Pediatrics · November 2020 Full text Cite

Methamphetamine‐induced Acute Esophagitis in a 16‐Year‐old Girl

Journal article Journal of Pediatric Gastroenterology and Nutrition · April 2020 Full text Cite

Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia

Journal article Journal of Allergy and Clinical Immunology · May 2019 Full text Cite