John Griffith Toffaletti

Journal article Nephron Clin Pract · 2010 Featured Publication The serious limitations of the estimating glomerular filtration rate (eGFR) appear related not to a shortcoming of the equation, but to the futility of trying to force agreement between two inherently different parameters: a blood marker of kidney function ... Full text Link to item Cite

Variation of serum creatinine, cystatin C, and creatinine clearance tests in persons with normal renal function.

Journal article Clin Chim Acta · September 2008 Featured Publication BACKGROUND: To determine the potential sensitivity of several renal function tests for detecting early changes in renal function, we compared the within-individual (W-I) variation over 5 months of serum creatinine, serum cystatin C, and creatinine clearanc ... Full text Link to item Cite

Changing systems for measuring activated clotting times: impact on the clinical practice of heparin anticoagulation during cardiac surgery.

Journal article Clin Chim Acta · June 2005 Featured Publication BACKGROUND: The activated clotting time (ACT) is a standard monitor for heparin anticoagulation during cardiopulmonary bypass (CPB). This study determines the effect of upgrading our ACT system on our clinical practice with regards to the conduct and safet ... Full text Link to item Cite

The relationship between ionized and total serum magnesium concentrations during abdominal surgery.

Journal article J Clin Anesth · June 2003 Featured Publication STUDY OBJECTIVE: To determine the necessity for ionized magnesium (iMg) assay by evaluating the effect of abdominal surgery without massive transfusion on total magnesium (Mg) and iMg concentrations. DESIGN: Prospective, observational study. SETTING: Opera ... Full text Link to item Cite

pH effects on measurements of ionized calcium and ionized magnesium in blood.

Journal article Arch Pathol Lab Med · August 2002 Featured Publication CONTEXT: It is well known that the concentration of ionized calcium in blood is affected by the pH of the specimen, since hydrogen ions compete with calcium for binding sites on albumin and other proteins. However, the relationship between pH and ionized m ... Full text Link to item Cite

Pneumatic transport exacerbates interference of room air contamination in blood gas samples.

Journal article Arch Pathol Lab Med · July 1996 Featured Publication OBJECTIVE: To characterize and control the potential interference to P(O2) determinations when blood contaminated with air is sent via a pneumatic tube system (PTS). DESIGN: Both tonometered blood at P(O2)s of 65, 75, 142, and 339 mm Hg and arterial blood ... Link to item Cite