Melissa DePaoli Johnson

Journal article Curr Infect Dis Rep · October 2007 Featured Publication Osteoarticular complications may occur with a variety of invasive fungal infections, and seem to be increasing with growing use of prosthetic joints and as the immunosuppressed patient population increases. Epidemiology, pathogenesis, presentation, and man ... Full text Link to item Cite

Combination antifungal therapy.

Journal article Antimicrob Agents Chemother · March 2004 Featured Publication Full text Link to item Cite

Caspofungin: first approved agent in a new class of antifungals.

Journal article Expert Opin Pharmacother · May 2003 Featured Publication Caspofungin (Cancidas, Merck & Co. Inc.) is the first echinocandin antifungal agent to gain FDA-approval for use in the US. It has excellent clinical activity against Candida spp. and Aspergillus spp. but lacks significant activity against Cryptococcus neo ... Full text Link to item Cite

A randomized comparative study to determine the effect of omeprazole on the peak serum concentration of itraconazole oral solution.

Journal article J Antimicrob Chemother · February 2003 Featured Publication To determine the effect of omeprazole on peak serum concentrations (C(max)) of itraconazole oral solution (IOS), we carried out a randomized, open-label, prospective, crossover study. Fifteen healthy, non-pregnant adults received a single dose of IOS 400 m ... Full text Link to item Cite

Steady-state pharmacokinetics of lamivudine in human immunodeficiency virus-infected patients with end-stage renal disease receiving chronic dialysis.

Journal article Antimicrob Agents Chemother · August 2002 Featured Publication The steady-state pharmacokinetics of lamivudine were evaluated in 11 subjects with human immunodeficiency virus infection and end-stage renal disease, 9 of whom were receiving hemodialysis and 2 of whom were receiving chronic ambulatory peritoneal dialysis ... Full text Link to item Cite

Chest discomfort associated with liposomal amphotericin B: report of three cases and review of the literature.

Journal article Pharmacotherapy · 1998 Featured Publication Liposomal formulations of amphotericin B are designed to maintain therapeutic efficacy of amphotericin B deoxycholate while reducing its associated toxicities. In three patients chest discomfort occurred during planned 1-hour infusions of liposomal amphote ... Link to item Cite