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Jonathan Paul Piccini Sr.

Ursula Geller Distinguished Professor of Research in Cardiovascular Diseases
Medicine, Cardiology
Duke Box 31115, Durham, NC 27710
Dept of Medicine, Durham, NC 27710

Featured Works


Use of ventricular synchronized triggered atrial pacing to facilitate hemodynamic support during mapping and catheter ablation of ventricular vachycardia.

Journal article J Cardiovasc Electrophysiol · October 2011 Featured Publication Use of VSTAP to Facilitate Hemodynamic Support. The ablation of hemodynamically unstable ventricular tachycardia (VT) is challenging and frequently requires alternative mapping techniques or the use of percutaneous mechanical support devices. Loss of atrio ... Full text Link to item Cite

Mortality benefits from implantable cardioverter-defibrillator therapy are not restricted to patients with remote myocardial infarction: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT).

Journal article Heart Rhythm · March 2011 Featured Publication BACKGROUND: The implantable cardioverter-defibrillator (ICD) is an effective therapy for preventing sudden cardiac death (SCD) in patients with prior myocardial infarction (MI) and reduced left ventricular function; however, the optimal timing of ICD impla ... Full text Link to item Cite

Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction.

Journal article Crit Care Med · January 2011 Featured Publication OBJECTIVE: Few data exist to guide antiarrhythmic drug therapy for sustained ventricular tachycardia/ventricular fibrillation after acute myocardial infarction. The objective of this analysis was to describe the survival of patients with sustained ventricu ... Full text Link to item Cite

Single-photon emission computed tomography myocardial perfusion imaging and the risk of sudden cardiac death in patients with coronary disease and left ventricular ejection fraction>35%.

Journal article J Am Coll Cardiol · July 13, 2010 Featured Publication OBJECTIVES: The aim of this study was to determine whether single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is an effective method of risk stratification for sudden cardiac death (SCD) in patients with coronary artery d ... Full text Link to item Cite

Optimal timing of implantable cardioverter-defibrillator implantation after myocardial infarction: a decision analysis.

Journal article J Cardiovasc Electrophysiol · July 2010 Featured Publication BACKGROUND: The optimal timing of implantable cardioverter defibrillator (ICD) placement for the primary prevention of sudden cardiac death after myocardial infarction (MI) remains unknown. METHODS AND RESULTS: We developed a Markov model to investigate th ... Full text Link to item Cite

Predictors of sudden cardiac death change with time after myocardial infarction: results from the VALIANT trial.

Journal article Eur Heart J · January 2010 Featured Publication AIMS: To determine whether predictors of sudden cardiac death (SCD) vary with time after myocardial infarction (MI). METHODS AND RESULTS: We analysed 11 256 patients enrolled in VALIANT. Landmark analysis and Cox proportional hazards modelling were used to ... Full text Link to item Cite

Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials.

Journal article Circ Arrhythm Electrophysiol · December 2009 Featured Publication BACKGROUND: Catheter ablation is an established yet evolving nonpharmacologic intervention for the maintenance of sinus rhythm in patients with atrial fibrillation (AF). The efficacy and safety of pulmonary vein isolation (PVI) compared with medical therap ... Full text Link to item Cite

Quality of care for atrial fibrillation among patients hospitalized for heart failure.

Journal article J Am Coll Cardiol · September 29, 2009 Featured Publication OBJECTIVES: This study sought to examine quality of care and warfarin use at discharge in patients with atrial fibrillation (AF) and heart failure (HF). BACKGROUND: Atrial fibrillation is common in HF, and national guidelines recommend discharge on warfari ... Full text Link to item Cite

Comparative efficacy of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation.

Journal article J Am Coll Cardiol · September 15, 2009 Featured Publication OBJECTIVES: We sought to compare the efficacy and safety of dronedarone versus amiodarone for the prevention of recurrent atrial fibrillation (AF). BACKGROUND: Dronedarone is a noniodinated amiodarone congener developed to maintain sinus rhythm. Few data a ... Full text Link to item Cite

Use of cardiac resynchronization therapy in patients hospitalized with heart failure.

Journal article Circulation · August 26, 2008 Featured Publication BACKGROUND: The frequency and characterization of patients receiving cardiac resynchronization therapy (CRT) are largely unknown since the publication of pivotal clinical trials and subsequent incorporation of CRT into the American College of Cardiology/Am ... Full text Link to item Cite

Predictors of appropriate implantable defibrillator therapies in patients with arrhythmogenic right ventricular dysplasia.

Journal article Heart Rhythm · November 2005 Featured Publication BACKGROUND: Arrhythmogenic right ventricular dysplasia (ARVD) is an inherited cardiomyopathy characterized by ventricular arrhythmias and sudden cardiac death. The risk factors for sudden death and indications for implantable cardioverter-defibrillator (IC ... Full text Link to item Cite

Electrocardiographic findings over time in arrhythmogenic right ventricular dysplasia/cardiomyopathy.

Journal article Am J Cardiol · July 1, 2005 Featured Publication Thirty-five patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy underwent serial electrocardiographic (ECG) testing and were evaluated for evidence of ECG progression. Over a median of 43 months, 89% of the patients had evidence of prog ... Full text Link to item Cite