Scholars@Duke

• Expertise
• 

  Subject Headings

  • Computational Biology
  • Machine learning
  • Statistics
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • McFarland, James M., Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan G. Bryan, John M. Krill-Burger, et al. “Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration.” Nature Communications 9, no. 1 (December 2018). https://doi.org/10.1038/s41467-018-06916-5.
       Full Text
    • Gray, Stacy W., Jeffrey Gagan, Ethan Cerami, Angel M. Cronin, Hajime Uno, Nelly Oliver, Carol Lowenstein, et al. “Interactive or static reports to guide clinical interpretation of cancer genomics.” Journal of the American Medical Informatics Association 25, no. 5 (May 1, 2018): 458–64. https://doi.org/10.1093/jamia/ocx150.
       Full Text
    • Meyers, Robin M., Jordan G. Bryan, James M. McFarland, Barbara A. Weir, Ann E. Sizemore, Han Xu, Neekesh V. Dharia, et al. “Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells.” Nature Genetics 49, no. 12 (December 2017): 1779–84. https://doi.org/10.1038/ng.3984.
       Full Text
    • Mackey, Lester, Jordan Bryan, and Man Yue Mo. “Weighted Classification Cascades for Optimizing Discovery Significance in the HiggsML Challenge.” Edited by Glen Cowan, Cécile Germain, Isabelle Guyon, Balázs Kégl, and David Rousseau. Proceedings of the Nips 2014 Workshop on High Energy Physics and Machine Learning 42 (December 13, 2015): 129–34.
• Scholarly, Clinical, & Service Activities
• 

  Presentations & Appearances

  • CERES: A New Approach to Correct for Copy Number in CRISPR-Cas9 Screens. CTD^2 D-HIP Webinar Series. CTD^2 Network. July 12, 2018  2018
  • CERES—A model for inferring genetic dependencies in cancer cell lines from CRISPR knockout screens. Meeting on Biological Data Science. Cold Spring Harbor Laboratory. October 26, 2016  2016

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.