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Jordan Franklin

House Staff
Medicine

Scholarly Works


l-2-Hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression

Journal article Journal of Clinical Investigation · May 1, 2026 High levels of l- and d-2-hydroxyglutarate (2HG), the reduced forms of α-ketoglutarate (αKG), are implicated in neurodevelopmental disorders and cancer by modulating αKG-dependent dioxygenases involved in histone, DNA, and RNA ... Full text Cite

False negative breast cancers on imaging and associated risk factors: a single institution six-year analysis.

Journal article Breast cancer research and treatment · June 2024 PurposeMitigating false negative imaging studies remains an important issue given its association with worse morbidity and mortality in patients with breast cancer. We aimed to identify risk factors that predispose to false negative breast imaging ... Full text Cite