Scholars@Duke
Jorn Coers

Jorn Coers

Alter Geller Distinguished Professor for Research in Immunology
Molecular Genetics and Microbiology

Scholarly Works - Conferences

An Aging-Susceptible Circadian Rhythm Controls Cutaneous Antiviral Immunity.

Conference bioRxiv · April 18, 2023 Aged skin is prone to viral infections, but the mechanisms responsible for this immunosenescent immune risk are unclear. We observed that aged murine and human skin expressed reduced antiviral proteins (AVPs) and circadian regulators including Bmal1 and Cl ... Full text Link to item Cite

An ancestral mycobacterial effector promotes dissemination of infection

Conference MOLECULAR BIOLOGY OF THE CELL · February 1, 2023 Link to item Cite

An ancestral mycobacterial effector promotes dissemination of infection

Conference MOLECULAR BIOLOGY OF THE CELL · February 1, 2023 Link to item Cite

IRF3 inhibits IFN-γ-mediated restriction of intracellular pathogens in macrophages independently of IFNAR.

Conference J Leukoc Biol · August 2022 Macrophages use an array of innate immune sensors to detect intracellular pathogens and to tailor effective antimicrobial responses. In addition, extrinsic activation with the cytokine IFN-γ is often required as well to tip the scales of the host-pathogen ... Full text Link to item Cite

ID: 260

Conference Cytokine · November 2015 Full text Cite

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins.

Conference Proc Natl Acad Sci U S A · October 13, 2015 Many microbes create and maintain pathogen-containing vacuoles (PVs) as an intracellular niche permissive for microbial growth and survival. The destruction of PVs by IFNγ-inducible guanylate binding protein (GBP) and immunity-related GTPase (IRG) host pro ... Full text Link to item Cite