Jorn Coers

Preprint · February 15, 2024 Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen Chlamydia trach ... Full text Link to item Cite

The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation

Preprint · January 10, 2024 AbstractMany cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. T ... Full text Cite

The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation.

Preprint · October 30, 2023 Full text Link to item Cite

Differential requirement for IRGM proteins during tuberculosis infection in mice

Preprint · 2022 ABSTRACT Mycobacterium tuberculosis ( Mtb ) is a bacterium that exclusively resides in human hosts and remains a dominant cause of morbidity and mortality among infectious diseases worldwide. Host protection against Mtb infection is dependent o ... Full text Cite