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Overview


My research focus is understanding the earliest processes of disease initiation and progression using systems biology and lineage tracing.

PhD from Duke University Department of Cell Biology in 2025.

Current Duke Appointments & Affiliations


Postdoctoral Associate Cell Biology, Basic Science Departments

Recent News Items


Published June 1, 2026
DMM Outstanding Paper Prize 2025 winners: Joshua D. Ginzel and Victoria Ektnitphong
Published April 9, 2025
Cancer Screen Test
Published March 19, 2025
Disease Models & Mechanisms
First Person Interview – Joshua Ginzel

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Recent Scholarly Works


CoSiDeX: A hyperspectral fluorescent protein resource for highly multiplexed imaging.

Preprint · May 14, 2025 Fluorescent proteins (FPs) have revolutionized spatiotemporal observations in biology. Yet, the design of multiplexed assays remains constrained by limited spectral characterization and palette validation. Although over 1,000 FPs have been catalogued, syst ... Full text Link to item Cite

Nonlinear progression during the occult transition establishes cancer lethality.

Journal article Dis Model Mech · March 1, 2025 Cancer screening relies upon a linear model of neoplastic growth and progression. Yet, historical observations suggest that malignant progression is uncoupled from growth, which may explain the paradoxical increase in early-stage breast cancer detection wi ... Full text Open Access Link to item Cite

First person – Joshua Ginzel

Journal article Disease Models & Mechanisms · March 1, 2025 ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Jos ... Full text Cite
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Recent Grants


Tau Mediates Microtubule and Mitochondrial Dynamics to Control Cellular Organization and Alveolar Epithelial Repair

ResearchResearch Associate · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2029

Alveolar injury and repair in Pompe Disease

ResearchPostdoctoral Associate · Awarded by National Heart, Lung, and Blood Institute · 2025 - 2028

Therapeutic targeting of breast cancer and host immune responses at inflection points in the disease trajectory

ResearchResearch Assistant · Awarded by Department of Defense · 2021 - 2026

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