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Joshua Aaron Granek

Assistant Professor in Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Integrative Genomics
Box 2721, 10044 Hock Plaza, Durham, NC 27710
2424 Erwin Rd,, 10044 Hock Plaza, Durham, NC 27710

Overview


We have broad interests in using microbial genomics to understand how microbes interact with each other and their hosts. This interest includes the roles played by both beneficial and harmful bacteria, fungi, and viruses and how they interact with the immune system. We study single microbes and microbial communities, primarily using high-throughput sequencing methods. We have a particular interest in developing new experimental and analytical methods that leverage the power of high-throughput sequencing. We are also interested in using deep learning in microbiology research.

Current Appointments & Affiliations


Assistant Professor in Biostatistics & Bioinformatics · 2021 - Present Biostatistics & Bioinformatics, Division of Integrative Genomics, Biostatistics & Bioinformatics

Recent Publications


Glucagon-Like Peptide 1 Receptor (Glp1r) Deficiency Does Not Appreciably Alter Airway Inflammation or Gut-Lung Microbiome Axis in a Mouse Model of Obese Allergic Airways Disease and Bariatric Surgery.

Journal Article J Asthma Allergy · 2025 PURPOSE: High body mass index (≥30 kg/m2) is associated with asthma severity, and nearly 40% of asthma patients exhibit obesity. Furthermore, over 40% of patients with obesity and asthma that receive bariatric surgery no longer require asthma medication. I ... Full text Link to item Cite

Malassezia responds to environmental pH signals through the conserved Rim/Pal pathway.

Journal Article mBio · October 16, 2024 During mammalian colonization and infection, microorganisms must be able to rapidly sense and adapt to changing environmental conditions including alterations in extracellular pH. The fungus-specific Rim/Pal signaling pathway is one process that supports m ... Full text Link to item Cite
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Recent Grants


Prenatal maternal obesity and neurodevelopment: The mediating role of the microbiome and metabolome

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2029

Quantitative Methods for HIV/AIDS Research

Inst. Training Prgm or CMETraining Faculty · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2028

NSF Engineering Research Center for Precision Microbiome Engineering (PreMiEr)

ResearchInvestigator · Awarded by National Science Foundation · 2022 - 2027

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Education, Training & Certifications


Johns Hopkins University · 2006 Ph.D.