ConferenceJournal of Clinical Oncology · February 10, 2025
410Background:
Inflammasomes are multiprotein complexes that regulate inflammation-associated signaling pathways. Although in ...
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ConferenceAnesthesiology · May 1, 2024
BACKGROUND: Anesthesia and/or surgery accelerate Alzheimer's disease pathology and cause memory deficits in animal models, yet there is a lack of prospective data comparing cerebrospinal fluid (CSF) Alzheimer's disease-related biomarker and cognitive traje ...
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ConferenceJournal of Clinical Oncology · February 1, 2024
84 Background: 2 studies found significantly longer overall survival in Black vs. White patients with metastatic castration-resistant prostate cancer (PCa): a 2019 meta-analysis of 9 phase III trials and a 2020 registry study. Ou ...
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ConferenceUrology · May 2023
OBJECTIVE: To assess how the validated Prostate Health Index (PHI) risk stratifications perform with African American (AA) men and establish a threshold PHI value to potentially rule out the need for prostate biopsy. MATERIALS AND METHODS: AA men meeting F ...
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ConferenceJournal of Clinical Oncology · February 20, 2018
382 Background: Nearly one third of men treated with curative intent for localized prostate cancer (PC) will develop a rising PSA. The rate of PSA rise (PSA doubling time aka PSASDT) is a predictor metastases and PC death. In lab ...
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ConferenceJournal of Clinical Oncology · May 20, 2017
e16566 Background: A CCP score has been developed and validated to provide prognostic information in prostate cancer. To date, our studies have exclusively used qRT-PCR to measure CCP gene expression, which is generally considere ...
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ConferenceJournal of Clinical Oncology · February 20, 2017
e589 Background: Leuprolide acetate (LA) is the standard-of-care luteinizing hormone-releasing hormone (LHRH) agonist used to suppress serum testosterone (T) in the treatment of advanced prostate cancer. There are currently two L ...
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ConferenceProstate Cancer Prostatic Dis · March 2016
BACKGROUND: In men with high Gleason PC and rapid PSA progression after surgery, failure rates remain unacceptably high despite salvage radiation. We explored a novel multimodality approach of docetaxel with anti-angiogenic therapy before salvage radiother ...
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ConferenceJournal of Clinical Oncology · January 10, 2016
84 Background: Active surveillance (AS) is an increasingly popular treatment modality for men with localized prostate cancer. Recently, we developed a method to select men for AS based on a score that combines cell cycle progress ...
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ConferenceJournal of Clinical Oncology · February 20, 2013
139 Background: The post-radical prostatectomy (RP) CAPRA-S nomogram stratifies men into low, intermediate and high risk groups for biochemical recurrence (BCR) and proved accurate for predicting 3 and 5 year BCR rates in a large ...
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ConferenceJournal of Clinical Oncology · March 1, 2011
47 Background: ProsVue is an investigational PSA immunoassay whose reporter antibody is labeled with a synthetic DNA sequence. RT-PCR detects the DNA signal indicating the PSA concentration. Pilot studies showed ProsVue slope (le ...
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ConferenceJournal of Clinical Oncology · March 1, 2011
12 Background: Comparative effectiveness of the gonadotropin-releasing hormone (GnRH) blocker, degarelix, vs the GnRH agonist, leuprolide, was evaluated during a 1-year phase III trial (CS21); data have been presented. We now rep ...
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ConferenceLecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics · January 1, 2000
Prostate cancer is the leading cause of death for American men. The gold standard for diagnosis of prostate cancer is transrectal ultrasound-guided needle core biopsy. Unfortunately, no imaging modality, including ultrasound, can effectively differentiate ...
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ConferenceLecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics · January 1, 1998
The diagnosis of localized prostate cancer is carried out by standard core needle biopsies under guidance of transrectal ultrasound imaging of the prostate gland. This paper describes a 3-D model supported virtual environment for prostate cancer diagnosis ...
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ConferenceProceedings Pacific Medical Technology Symposium Transcending Time Distance and Structural Barriers Pacmedtek 1998 · January 1, 1998
The diagnosis of localized prostate cancer is carried out by standard core needle biopsies under guidance of transrectal ultrasound imaging of the prostate gland. This paper describes a 3D model supported virtual environment for prostate cancer diagnosis a ...
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ConferenceProceedings Pacific Medical Technology Symposium Transcending Time Distance and Structural Barriers Pacmedtek 1998 · January 1, 1998
To detect prostate cancer urologists routinely use the systematic sextant needle biopsy technique. This patterned biopsy technique has been adopted with little quantitative or scientific evidence to support its use. Using 136 digitized radical prostatectom ...
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