Junjie Yao
Assistant Professor of Biomedical Engineering
Our mission at PI-Lab is to develop state-of-the-art photoacoustic tomography (PAT) technologies and translate PAT advances into diagnostic and therapeutic applications, especially in functional brain imaging and early cancer theranostics. PAT is the most sensitive modality for imaging rich optical absorption contrast over a wide range of spatial scales at high speed, and is one of the fastest growing biomedical imaging technologies. Using numerous endogenous and exogenous contrasts, PAT can provide high-resolution images at scales covering organelles, cells, tissues, organs, small-animal organisms, up to humans, and can reveal tissue’s anatomical, functional, metabolic, and even histologic properties, with molecular and neuronal specificity.
At PI-Lab, we develop PAT technologies with novel and advanced imaging performance, in terms of spatial resolutions, imaging speed, penetration depth, detection sensitivity, and functionality. We are interested with all aspects of PAT technology innovations, including efficient light illumination, high-sensitivity ultrasonic detection, super-resolution PAT, high-speed imaging acquisition, novel PA genetic contrast, and precise image reconstruction. On top of the technological advancements, we are devoted to serve the broad life science and medical communities with matching PAT systems for various research and clinical needs. With its unique contrast mechanism, high scalability, and inherent functional and molecular imaging capabilities, PAT is well suited for a variety of pre-clinical applications, especially for studying tumor angiogenesis, cancer hypoxia, and brain disorders; it is also a promising tool for clinical applications in procedures such as cancer screening, melanoma staging, and endoscopic examination.
Current Research Interests
Office Hours
Current Appointments & Affiliations
- Assistant Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2016
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2017
- Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2018
Contact Information
- Hudson Hall Annex 261, Durham, NC 27708
- Room 1427, Fitzpatrick Ciemas, 101 Science Drive, PO Box 90281, Durham, NC 27708
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junjie.yao@duke.edu
(919) 681-0694
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Duke Photoacoustics Lab website
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Google Scholar
- Background
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Education, Training, & Certifications
- Ph.D., Washington University in St. Louis 2012
- Recognition
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In the News
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JAN 3, 2023 Pratt School of Engineering -
MAY 31, 2022 Pratt School of Engineering -
MAY 24, 2022 Pratt School of Engineering -
JAN 24, 2022 Duke Engineering News -
NOV 12, 2020 -
FEB 13, 2019 Pratt School of Engineering -
JUL 27, 2018 Duke University School of Medicine Alumni News Magazine -
MAY 10, 2017 Pratt School of Engineering -
OCT 30, 2016
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Awards & Honors
- Early Career Development (CAREER) Award. National Science Foundation (NSF). 2022
- Fellow. Optica (formally OSA). 2022
- 2019 Young Investigator Award. IEEE Photonics Society . 2019
- Collaborative Sciences Award. American Heart Association . July 1, 2018
- OSA/Quantel Bright Idea Competition (Finalist). Optical Society of America. May 2017
- Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2016: Imaging and Sensing. February 2016
- Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2015: Imaging and Sensing . February 2015
- Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2013: Imaging and Sensing . February 2013
- Chinese Government Award for Outstanding Self-financed Students Aboard. The Education Ministry of China. December 2012
- Best Master Dissertation Award. Tsinghua University. July 2008
- Comprehensive Student Fellowship. Tsinghua University. January 2008
- KangShien Outstanding Graduate Fellowship. Tsinghua University. July 2006
- CyrusTang Fellowship (2002-2006). Tsinghua University. September 2002
- Expertise
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Subject Headings
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Global Scholarship
- Research
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Selected Grants
- CAREER: Mapping deep brain functions with super-resolution protoacoustic imaging awarded by National Science Foundation 2022 - 2027
- Innovations in Shock Wave Lithotripsy Technology awarded by National Institutes of Health 1997 - 2026
- Platelet-mast cell interactions in pathogen induced vascular pathology awarded by National Institutes of Health 2021 - 2025
- Targeted neuromodulation to enhance recovery of the aged brain after ischemic stroke awarded by National Institutes of Health 2022 - 2024
- High-resolution High-speed Photoacoustic and Ultrasound Imaging of Small Vessels Functions in Ischemic Stroke awarded by National Institutes of Health 2019 - 2024
- 3D Functional Photoacoustic Imaging of Human Brain with a Stretchable Ultrasound Matrix Array awarded by Pennsylvania State University 2021 - 2023
- Transcranial photoacoustic imaging using a virtual array awarded by Pennsylvania State University 2020 - 2023
- Sub-Diffraction Deep Photoacoustic Imaging with NIR photochromic Probes awarded by Albert Einstein College of Medicine 2021 - 2023
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2023
- Head-mounted Photoacoustic Imaging of Deep-brain Neural Activities in Freely Behaving Animals awarded by National Institutes of Health 2020 - 2023
- High-Throughput Volumetric Photoacoustic Imaging of Living Vascularized Organoids awarded by National Institutes of Health 2019 - 2022
- A turnkey research platform to accelerate clinical translation of targeted immunomodulation-enhanced therapies awarded by SonoVol, Inc. 2021 - 2022
- Whole-organ bioreactor with integrated nondestructive 3D molecular imaging awarded by SonoVol, Inc. 2019 - 2022
- Photoacoustic-Imaging-Guided Intravascular Sonothrombolysis awarded by North Carolina State University 2019 - 2021
- Development of a Longitudinal Molecular Imaging Platform to Support Immuno-Oncology Research awarded by SonoVol, Inc. 2019 - 2020
- A turnkey research platform to accelerate clinical translation of focused-ultrasound (FUS) oncology therapies awarded by SonoVol, Inc. 2019 - 2020
- Evaluation of the accuracy of computer-guided laser delivery versus a human-operator for cutaneous applications awarded by American Society for Dermatologic Surgery 2019 - 2020
- Training in Medical Imaging awarded by National Institutes of Health 2003 - 2020
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Menozzi, Luca, Ángela Del Águila, Tri Vu, Chenshuo Ma, Wei Yang, and Junjie Yao. “Three-dimensional non-invasive brain imaging of ischemic stroke by integrated photoacoustic, ultrasound and angiographic tomography (PAUSAT).” Photoacoustics 29 (February 2023): 100444. https://doi.org/10.1016/j.pacs.2022.100444.Full Text
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Tang, Yuqi, Shanshan Tang, Chengwu Huang, Paul Klippel, Chenshuo Ma, Nathan Caso, Shigao Chen, Yun Jing, and Junjie Yao. “High-fidelity deep functional photoacoustic tomography enhanced by virtual point sources.” Photoacoustics 29 (February 2023): 100450. https://doi.org/10.1016/j.pacs.2023.100450.Full Text
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Oliinyk, Olena S., Chenshuo Ma, Sergei Pletnev, Mikhail Baloban, Carlos Toboada, Huaxin Sheng, Junjie Yao, and Vladislav V. Verkhusha. “Deep-tissue SWIR imaging using rationally designed small red-shifted near-infrared fluorescent protein.” Nature Methods 20, no. 1 (January 2023): 70–74. https://doi.org/10.1038/s41592-022-01683-0.Full Text
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Chen, Maomao, Laiming Jiang, Clare Cook, Yushun Zeng, Tri Vu, Ruimin Chen, Gengxi Lu, et al. “High-speed wide-field photoacoustic microscopy using a cylindrically focused transparent high-frequency ultrasound transducer.” Photoacoustics 28 (December 2022): 100417. https://doi.org/10.1016/j.pacs.2022.100417.Full Text
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Kilian, Hailey I., Chenshuo Ma, Huijuan Zhang, Maomao Chen, Anoop Nilam, Breandan Quinn, Yuqi Tang, Jun Xia, Junjie Yao, and Jonathan F. Lovell. “Intraperitoneal administration for sustained photoacoustic contrast agent imaging.” Photoacoustics 28 (December 2022): 100406. https://doi.org/10.1016/j.pacs.2022.100406.Full Text
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Taboada, Carlos, Jesse Delia, Maomao Chen, Chenshuo Ma, Xiaorui Peng, Xiaoyi Zhu, Laiming Jiang, et al. “Glassfrogs conceal blood in their liver to maintain transparency.” Science (New York, N.Y.) 378, no. 6626 (December 2022): 1315–20. https://doi.org/10.1126/science.abl6620.Full Text
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Li, Mucong, Nathan Beaumont, Chenshuo Ma, Juan Rojas, Tri Vu, Max Harlacher, Graeme O’Connell, et al. “Three-Dimensional Deep-Tissue Functional and Molecular Imaging by Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT).” Ieee Transactions on Medical Imaging 41, no. 10 (October 2022): 2704–14. https://doi.org/10.1109/tmi.2022.3168859.Full Text
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Zhang, Ruiying, Lei S. Li, Bin Rao, Haoyang Rong, Min-Yu Sun, Junjie Yao, Ruimin Chen, et al. “Multiscale photoacoustic tomography of neural activities with GCaMP calcium indicators.” Journal of Biomedical Optics 27, no. 9 (September 2022). https://doi.org/10.1117/1.jbo.27.9.096004.Full Text
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Chen, Junqin, Daiwei Li, Wenjun Yu, Zhiteng Ma, Chenhang Li, Gaoming Xiang, Yuan Wu, Junjie Yao, and Pei Zhong. “The Effects of Scanning Speed and Standoff Distance of the Fiber on Dusting Efficiency during Short Pulse Holmium: YAG Laser Lithotripsy.” J Clin Med 11, no. 17 (August 28, 2022). https://doi.org/10.3390/jcm11175048.Full Text Link to Item
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Zhu, Xiaoyi, Qiang Huang, Anthony DiSpirito, Tri Vu, Qiangzhou Rong, Xiaorui Peng, Huaxin Sheng, et al. “Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy.” Light Sci Appl 11, no. 1 (May 17, 2022): 138. https://doi.org/10.1038/s41377-022-00836-2.Full Text Open Access Copy Link to Item
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Kasatkina, Ludmila A., Chenshuo Ma, Mikhail E. Matlashov, Tri Vu, Mucong Li, Andrii A. Kaberniuk, Junjie Yao, and Vladislav V. Verkhusha. “Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model.” Nature Communications 13, no. 1 (May 2022): 2813. https://doi.org/10.1038/s41467-022-30547-6.Full Text
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Tang, Yuqi, Huaiyu Wu, Paul Klippel, Bohua Zhang, Hsiao-Ying Shadow Huang, Yun Jing, Xiaoning Jiang, and Junjie Yao. “Deep thrombosis characterization using photoacoustic imaging with intravascular light delivery.” Biomedical Engineering Letters 12, no. 2 (May 2022): 135–45. https://doi.org/10.1007/s13534-022-00216-0.Full Text
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Zhang, Huijuan, Wei Bo, Depeng Wang, Anthony DiSpirito, Chuqin Huang, Nikhila Nyayapathi, Emily Zheng, et al. “Deep-E: A Fully-Dense Neural Network for Improving the Elevation Resolution in Linear-Array-Based Photoacoustic Tomography.” Ieee Transactions on Medical Imaging 41, no. 5 (May 2022): 1279–88. https://doi.org/10.1109/tmi.2021.3137060.Full Text
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Duan, Tingyang, Xiaorui Peng, Maomao Chen, Dong Zhang, Fei Gao, and Junjie Yao. “Detection of weak optical absorption by optical-resolution photoacoustic microscopy.” Photoacoustics 25 (March 2022): 100335. https://doi.org/10.1016/j.pacs.2022.100335.Full Text
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Dong, Biqin, Junjie Yao, and Xosé Luís Deán-Ben. “Editorial: Advances in Photoacoustic Neuroimaging.” Frontiers in Neuroscience 16 (January 2022): 859515. https://doi.org/10.3389/fnins.2022.859515.Full Text
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Ma, Chenshuo, Wanlu Li, Daiwei Li, Maomao Chen, Mian Wang, Laiming Jiang, Luis Santiago Mille, et al. “Photoacoustic imaging of 3D-printed vascular networks.” Biofabrication 14, no. 2 (January 2022). https://doi.org/10.1088/1758-5090/ac49d5.Full Text
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Menozzi, Luca, Wei Yang, Wuwei Feng, and Junjie Yao. “Sound out the impaired perfusion: Photoacoustic imaging in preclinical ischemic stroke.” Frontiers in Neuroscience 16 (January 2022): 1055552. https://doi.org/10.3389/fnins.2022.1055552.Full Text
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Chen, Maomao, Xiaoyu Duan, Bangxin Lan, Tri Vu, Xiaoyi Zhu, Qiangzhou Rong, Wei Yang, Ulrike Hoffmann, Jun Zou, and Junjie Yao. “High-speed functional photoacoustic microscopy using a water-immersible two-axis torsion-bending scanner.” Photoacoustics 24 (December 2021): 100309. https://doi.org/10.1016/j.pacs.2021.100309.Full Text
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Li, Daiwei, Lucas Humayun, Emelina Vienneau, Tri Vu, and Junjie Yao. “Seeing through the Skin: Photoacoustic Tomography of Skin Vasculature and Beyond.” Jid Innovations : Skin Science From Molecules to Population Health 1, no. 3 (September 2021): 100039. https://doi.org/10.1016/j.xjidi.2021.100039.Full Text
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Vu, Tri, Yuqi Tang, Mucong Li, Georgii Sankin, Shanshan Tang, Shigao Chen, Pei Zhong, and Junjie Yao. “Photoacoustic computed tomography of mechanical HIFU-induced vascular injury.” Biomedical Optics Express 12, no. 9 (September 2021): 5489–98. https://doi.org/10.1364/boe.426660.Full Text
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Li, Mucong, Juanjuan Gu, Tri Vu, Georgy Sankin, Pei Zhong, Junjie Yao, and Yun Jing. “Time-Resolved Passive Cavitation Mapping Using the Transient Angular Spectrum Approach.” Ieee Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 68, no. 7 (July 2021): 2361–69. https://doi.org/10.1109/tuffc.2021.3062357.Full Text
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Mac Grory, Brian, Matthew Schrag, Sven Poli, Chantal J. Boisvert, Martin S. Spitzer, Maximillian Schultheiss, Max Nedelmann, et al. “Structural and Functional Imaging of the Retina in Central Retinal Artery Occlusion - Current Approaches and Future Directions.” J Stroke Cerebrovasc Dis 30, no. 7 (July 2021): 105828. https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105828.Full Text Link to Item
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Xia, Jun, Muyinatu A. Lediju Bell, Jan Laufer, and Junjie Yao. “Translational Photoacoustic Imaging for Disease Diagnosis, Monitoring, and Surgical Guidance: introduction to the feature issue.” Biomedical Optics Express 12, no. 7 (July 2021): 4115–18. https://doi.org/10.1364/boe.430421.Full Text
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Zhang, Dong, Ran Li, Maomao Chen, Tri Vu, Huaxin Sheng, Wei Yang, Ulrike Hoffmann, Jianwen Luo, and Junjie Yao. “Photoacoustic imaging of in vivo hemodynamic responses to sodium nitroprusside.” J Biophotonics 14, no. 7 (July 2021): e202000478. https://doi.org/10.1002/jbio.202000478.Full Text Open Access Copy Link to Item
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DiSpirito, Anthony, Tri Vu, Manojit Pramanik, and Junjie Yao. “Sounding out the hidden data: A concise review of deep learning in photoacoustic imaging.” Experimental Biology and Medicine (Maywood, N.J.) 246, no. 12 (June 2021): 1355–67. https://doi.org/10.1177/15353702211000310.Full Text
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Vu, T., A. DiSpirito, D. Li, Z. Wang, X. Zhu, M. Chen, L. Jiang, et al. “Deep image prior for undersampling high-speed photoacoustic microscopy.” Photoacoustics 22 (June 1, 2021). https://doi.org/10.1016/j.pacs.2021.100266.Full Text
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Vu, Tri, Anthony DiSpirito, Daiwei Li, Zixuan Wang, Xiaoyi Zhu, Maomao Chen, Laiming Jiang, et al. “Deep image prior for undersampling high-speed photoacoustic microscopy.” Photoacoustics 22 (June 2021): 100266. https://doi.org/10.1016/j.pacs.2021.100266.Full Text
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Yao, Junjie, and Lihong V. Wang. “Perspective on fast-evolving photoacoustic tomography.” Journal of Biomedical Optics 26, no. 6 (June 2021). https://doi.org/10.1117/1.jbo.26.6.060602.Full Text
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Li, Honghui, Zhiyou Wu, Jinde Zhang, Xiang Sun, Fei Duan, Junjie Yao, Mingyang Sun, Jiaqiang Zhang, and Liming Nie. “Instant Ultrasound-Evoked Precise Nanobubble Explosion and Deep Photodynamic Therapy for Tumors Guided by Molecular Imaging.” Acs Applied Materials & Interfaces 13, no. 18 (May 2021): 21097–107. https://doi.org/10.1021/acsami.1c05517.Full Text
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Liang, Bingyang, Shaomeng Wang, Fei Shen, Qing Huo Liu, Yubin Gong, and Junjie Yao. “Acoustic impact of the human skull on transcranial photoacoustic imaging.” Biomedical Optics Express 12, no. 3 (March 2021): 1512–28. https://doi.org/10.1364/boe.420084.Full Text
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Shemetov, Anton A., Mikhail V. Monakhov, Qinrong Zhang, Jose Ernesto Canton-Josh, Manish Kumar, Maomao Chen, Mikhail E. Matlashov, et al. “A near-infrared genetically encoded calcium indicator for in vivo imaging.” Nat Biotechnol 39, no. 3 (March 2021): 368–77. https://doi.org/10.1038/s41587-020-0710-1.Full Text Link to Item
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Tang, Yuqi, and Junjie Yao. “3D Monte Carlo simulation of light distribution in mouse brain in quantitative photoacoustic computed tomography.” Quantitative Imaging in Medicine and Surgery 11, no. 3 (March 2021): 1046–59. https://doi.org/10.21037/qims-20-815.Full Text
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DiSpirito, Anthony, Daiwei Li, Tri Vu, Maomao Chen, Dong Zhang, Jianwen Luo, Roarke Horstmeyer, and Junjie Yao. “Reconstructing Undersampled Photoacoustic Microscopy Images Using Deep Learning.” Ieee Transactions on Medical Imaging 40, no. 2 (February 2021): 562–70. https://doi.org/10.1109/tmi.2020.3031541.Full Text
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Li, Mucong, Georgy Sankin, Tri Vu, Junjie Yao, and Pei Zhong. “Tri-modality cavitation mapping in shock wave lithotripsy.” The Journal of the Acoustical Society of America 149, no. 2 (February 2021): 1258. https://doi.org/10.1121/10.0003555.Full Text
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Humayun, Lucas, Colin Smith, Wanlu Li, Yu Shrike Zhang, Christine Park, Wuwei Feng, and Junjie Yao. “SARS-CoV-2-related vascular injury: mechanisms, imaging and models.” Microphysiological Systems 5 (January 2021): 1. https://doi.org/10.21037/mps-20-6.Full Text
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III, Anthony DiSpirito, Daiwei Li, Tri Vu, Maomao Chen, Dong Zhang, Jianwen Luo, Roarke Horstmeyer, and Junjie Yao. “Reconstructing Undersampled Photoacoustic Microscopy Images Using Deep Learning.” Ieee Trans. Medical Imaging 40 (2021): 562–70. https://doi.org/10.1109/TMI.2020.3031541.Full Text
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Li, Mucong, Tri Vu, Georgy Sankin, Brenton Winship, Kohldon Boydston, Russell Terry, Pei Zhong, and Junjie Yao. “Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-Scattering Fiber Diffuser.” Ieee Transactions on Medical Imaging 40, no. 1 (January 2021): 346–56. https://doi.org/10.1109/tmi.2020.3027199.Full Text
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Vu, Tri, Mucong Li, Hannah Humayun, Yuan Zhou, and Junjie Yao. “A generative adversarial network for artifact removal in photoacoustic computed tomography with a linear-array transducer.” Experimental Biology and Medicine (Maywood, N.J.) 245, no. 7 (April 2020): 597–605. https://doi.org/10.1177/1535370220914285.Full Text
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Li, Yang, Lei Li, Liren Zhu, Konstantin Maslov, Junhui Shi, Peng Hu, En Bo, et al. “Snapshot Photoacoustic Topography Through an Ergodic Relay for High-throughput Imaging of Optical Absorption.” Nature Photonics 14, no. 3 (March 2020): 164–70. https://doi.org/10.1038/s41566-019-0576-2.Full Text
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Li, Mucong, Bangxin Lan, Georgii Sankin, Yuan Zhou, Wei Liu, Jun Xia, Depeng Wang, Gregg Trahey, Pei Zhong, and Junjie Yao. “Simultaneous Photoacoustic Imaging and Cavitation Mapping in Shockwave Lithotripsy.” Ieee Transactions on Medical Imaging 39, no. 2 (February 2020): 468–77. https://doi.org/10.1109/tmi.2019.2928740.Full Text
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Li, Mucong, Nikhila Nyayapathi, Hailey I. Kilian, Jun Xia, Jonathan F. Lovell, and Junjie Yao. “Sound Out the Deep Colors: Photoacoustic Molecular Imaging at New Depths.” Molecular Imaging 19 (January 2020): 1536012120981518. https://doi.org/10.1177/1536012120981518.Full Text
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Onufer, Emily J., Bola Aladegbami, Toru Imai, Kristen Seiler, Adam Bajinting, Cathleen Courtney, Stephanie Sutton, et al. “EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis.” Plos One 15, no. 9 (January 2020): e0236964. https://doi.org/10.1371/journal.pone.0236964.Full Text
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Tang, Yuqi, Xuejun Qian, Darrin J. Lee, Qifa Zhou, and Junjie Yao. “From Light to Sound: Photoacoustic and Ultrasound Imaging in Fundamental Research of Alzheimer's Disease.” Obm Neurobiology 4, no. 2 (January 2020). https://doi.org/10.21926/obm.neurobiol.2002056.Full Text
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Vu, Tri, Daniel Razansky, and Junjie Yao. “Listening to tissues with new light: recent technological advances in photoacoustic imaging.” Journal of Optics (2010) 21, no. 10 (October 2019). https://doi.org/10.1088/2040-8986/ab3b1a.Full Text
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Chen, Maomao, Hailey J. Knox, Yuqi Tang, Wei Liu, Liming Nie, Jefferson Chan, and Junjie Yao. “Simultaneous photoacoustic imaging of intravascular and tissue oxygenation.” Optics Letters 44, no. 15 (August 2019): 3773–76. https://doi.org/10.1364/ol.44.003773.Full Text
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Liang, Bingyang, Wei Liu, Qiwei Zhan, Mucong Li, Mingwei Zhuang, Qing H. Liu, and Junjie Yao. “Impacts of the murine skull on high-frequency transcranial photoacoustic brain imaging.” Journal of Biophotonics 12, no. 7 (July 2019): e201800466. https://doi.org/10.1002/jbio.201800466.Full Text
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Humayun, Hannah, and Junjie Yao. “Imaging the aged brain: pertinence and methods.” Quantitative Imaging in Medicine and Surgery 9, no. 5 (May 2019): 842–57. https://doi.org/10.21037/qims.2019.05.06.Full Text
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Zhou, Yuan, Mucong Li, Wei Liu, Georgy Sankin, Jianwen Luo, Pei Zhong, and Junjie Yao. “Thermal Memory Based Photoacoustic Imaging of Temperature.” Optica 6, no. 2 (February 2019): 198–205. https://doi.org/10.1364/optica.6.000198.Full Text
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Lan, Bangxin, Wei Liu, Ya-Chao Wang, Junhui Shi, Yang Li, Song Xu, Huaxin Sheng, et al. “High-speed widefield photoacoustic microscopy of small-animal hemodynamics.” Biomed Opt Express 9, no. 10 (October 1, 2018): 4689–4701. https://doi.org/10.1364/BOE.9.004689.Full Text Open Access Copy Link to Item
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Shi, Junhui, Yuqi Tang, and Junjie Yao. “Advances in super-resolution photoacoustic imaging.” Quantitative Imaging in Medicine and Surgery 8, no. 8 (September 2018): 724–32. https://doi.org/10.21037/qims.2018.09.14.Full Text
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Tang, Yuqi, Wei Liu, Yang Li, Qifa Zhou, and Junjie Yao. “Concurrent photoacoustic and ultrasound microscopy with a coaxial dual-element ultrasonic transducer.” Visual Computing for Industry, Biomedicine, and Art 1, no. 1 (September 2018): 3. https://doi.org/10.1186/s42492-018-0003-4.Full Text
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Vienneau, Emelina, Wei Liu, and Junjie Yao. “Dual-view acoustic-resolution photoacoustic microscopy with enhanced resolution isotropy.” Optics Letters 43, no. 18 (September 2018): 4413–16. https://doi.org/10.1364/ol.43.004413.Full Text
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Yao, Junjie, and Lihong V. Wang. “Recent progress in photoacoustic molecular imaging.” Current Opinion in Chemical Biology 45 (August 2018): 104–12. https://doi.org/10.1016/j.cbpa.2018.03.016.Full Text
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Hsu, Hsun-Chia, Lei Li, Junjie Yao, Terence T. W. Wong, Junhui Shi, Ruimin Chen, Qifa Zhou, and Lihong Wang. “Dual-axis illumination for virtually augmenting the detection view of optical-resolution photoacoustic microscopy.” Journal of Biomedical Optics 23, no. 7 (July 1, 2018). https://doi.org/10.1117/1.JBO.23.7.076001.Full Text Link to Item
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Li, Lei, Anton A. Shemetov, Mikhail Baloban, Peng Hu, Liren Zhu, Daria M. Shcherbakova, Ruiying Zhang, et al. “Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo.” Nature Communications 9, no. 1 (July 2018): 2734. https://doi.org/10.1038/s41467-018-05231-3.Full Text
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Liu, Wei, Daria M. Shcherbakova, Neel Kurupassery, Yang Li, Qifa Zhou, Vladislav V. Verkhusha, and Junjie Yao. “Quad-mode functional and molecular photoacoustic microscopy.” Scientific Reports 8, no. 1 (July 2018): 11123. https://doi.org/10.1038/s41598-018-29249-1.Full Text
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Li, Mucong, Yuqi Tang, and Junjie Yao. “Photoacoustic tomography of blood oxygenation: A mini review.” Photoacoustics 10 (June 2018): 65–73. https://doi.org/10.1016/j.pacs.2018.05.001.Full Text
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Liu, Wei, and Junjie Yao. “Photoacoustic microscopy: principles and biomedical applications.” Biomedical Engineering Letters 8, no. 2 (May 2018): 203–13. https://doi.org/10.1007/s13534-018-0067-2.Full Text
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Qu, Yuan, Lei Li, Yuecheng Shen, Xiaoming Wei, Terence T. W. Wong, Peng Hu, Junjie Yao, Konstantin Maslov, and Lihong V. Wang. “Dichroism-sensitive photoacoustic computed tomography.” Optica 5, no. 4 (April 2018): 495–501. https://doi.org/10.1364/optica.5.000495.Full Text
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Zhang, Yu Shrike, and Junjie Yao. “Imaging Biomaterial-Tissue Interactions.” Trends in Biotechnology 36, no. 4 (April 2018): 403–14. https://doi.org/10.1016/j.tibtech.2017.09.004.Full Text
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Li, Mucong, Bangxin Lan, Wei Liu, Jun Xia, and Junjie Yao. “Internal-illumination photoacoustic computed tomography.” Journal of Biomedical Optics 23, no. 3 (March 2018): 1–4. https://doi.org/10.1117/1.jbo.23.3.030506.Full Text
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Liu, Wei, Yuan Zhou, Mengran Wang, Lei Li, Emelina Vienneau, Ruimin Chen, Jianwen Luo, et al. “Correcting the limited view in optical-resolution photoacoustic microscopy.” Journal of Biophotonics 11, no. 2 (February 2018). https://doi.org/10.1002/jbio.201700196.Full Text
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Zhou, Yuan, Eric Tang, Jianwen Luo, and Junjie Yao. “Deep-tissue temperature mapping by multi-illumination photoacoustic tomography aided by a diffusion optical model: a numerical study.” Journal of Biomedical Optics 23, no. 1 (January 2018): 1–10. https://doi.org/10.1117/1.jbo.23.1.016014.Full Text
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Saxena, Y., C. Kim, and J. Yao. “From bench to market: commercialization of photoacoustic imaging.” Hongwai Yu Jiguang Gongcheng/Infrared and Laser Engineering 46, no. 11 (November 25, 2017). https://doi.org/10.3788/IRLA201746.1103001.Full Text
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Liu, Wei, Bangxin Lan, Leo Hu, Ruimin Chen, Qifa Zhou, and Junjie Yao. “Photoacoustic thermal flowmetry with a single light source.” Journal of Biomedical Optics 22, no. 9 (September 2017): 1–6. https://doi.org/10.1117/1.jbo.22.9.096001.Full Text
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Brunker, Joanna, Junjie Yao, Jan Laufer, and Sarah E. Bohndiek. “Photoacoustic imaging using genetically encoded reporters: a review.” Journal of Biomedical Optics 22, no. 7 (July 2017). https://doi.org/10.1117/1.jbo.22.7.070901.Full Text
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Lin, Li, Junjie Yao, Ruiying Zhang, Chun-Cheng Chen, Chih-Hsien Huang, Yang Li, Lidai Wang, William Chapman, Jun Zou, and Lihong V. Wang. “High-speed photoacoustic microscopy of mouse cortical microhemodynamics.” Journal of Biophotonics 10, no. 6–7 (June 2017): 792–98. https://doi.org/10.1002/jbio.201600236.Full Text
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Yao, Junjie. “When pressure meets light: detecting the photoacoustic effect at the origin.” Light, Science & Applications 6, no. 6 (June 2017): e17062. https://doi.org/10.1038/lsa.2017.62.Full Text
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Lin, Li, Pengfei Zhang, Song Xu, Junhui Shi, Lei Li, Junjie Yao, Lidai Wang, Jun Zou, and Lihong V. Wang. “Handheld optical-resolution photoacoustic microscopy.” Journal of Biomedical Optics 22, no. 4 (April 2017): 41002. https://doi.org/10.1117/1.jbo.22.4.041002.Full Text
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Imai, Toru, Barbara Muz, Cheng-Hung Yeh, Junjie Yao, Ruiying Zhang, Abdel Kareem Azab, and Lihong Wang. “Direct measurement of hypoxia in a xenograft multiple myeloma model by optical-resolution photoacoustic microscopy.” Cancer Biology & Therapy 18, no. 2 (February 2017): 101–5. https://doi.org/10.1080/15384047.2016.1276137.Full Text
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Li, Lei, Liren Zhu, Cheng Ma, Li Lin, Junjie Yao, Lidai Wang, Konstantin Maslov, et al. “Single-impulse Panoramic Photoacoustic Computed Tomography of Small-animal Whole-body Dynamics at High Spatiotemporal Resolution.” Nature Biomedical Engineering 1, no. 5 (January 2017): 0071. https://doi.org/10.1038/s41551-017-0071.Full Text
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He, Yun, Lidai Wang, Junhui Shi, Junjie Yao, Lei Li, Ruiying Zhang, Chih-Hsien Huang, Jun Zou, and Lihong V. Wang. “In vivo label-free photoacoustic flow cytography and on-the-spot laser killing of single circulating melanoma cells.” Scientific Reports 6 (December 2016): 39616. https://doi.org/10.1038/srep39616.Full Text
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Wang, Lihong V., and Junjie Yao. “A practical guide to photoacoustic tomography in the life sciences.” Nature Methods 13, no. 8 (July 2016): 627–38. https://doi.org/10.1038/nmeth.3925.Full Text Open Access Copy
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Lin, Li, Junjie Yao, Lei Li, and Lihong V. Wang. “In vivo photoacoustic tomography of myoglobin oxygen saturation.” Journal of Biomedical Optics 21, no. 6 (June 2016): 61002. https://doi.org/10.1117/1.jbo.21.6.061002.Full Text
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Zhou, Yong, Junjie Yao, and Lihong V. Wang. “Tutorial on photoacoustic tomography.” Journal of Biomedical Optics 21, no. 6 (June 2016): 61007. https://doi.org/10.1117/1.jbo.21.6.061007.Full Text
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Hai, Pengfei, Junjie Yao, Guo Li, Chiye Li, and Lihong V. Wang. “Photoacoustic elastography.” Optics Letters 41, no. 4 (February 2016): 725–28. https://doi.org/10.1364/ol.41.000725.Full Text
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Yao, Junjie, Andrii A. Kaberniuk, Lei Li, Daria M. Shcherbakova, Ruiying Zhang, Lidai Wang, Guo Li, Vladislav V. Verkhusha, and Lihong V. Wang. “Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe.” Nature Methods 13, no. 1 (January 2016): 67–73. https://doi.org/10.1038/nmeth.3656.Full Text Open Access Copy
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Yao, Junjie, Jun Xia, and Lihong V. Wang. “Multiscale Functional and Molecular Photoacoustic Tomography.” Ultrasonic Imaging 38, no. 1 (January 2016): 44–62. https://doi.org/10.1177/0161734615584312.Full Text
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Yao, Junjie, Liang Song, and Lihing V. Wang. “Photoacoustic microscopy: superdepth, superresolution, and superb contrast.” Ieee Pulse 6, no. 3 (May 2015): 34–37. https://doi.org/10.1109/mpul.2015.2409100.Full Text
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Yao, Junjie, Lidai Wang, Joon-Mo Yang, Konstantin I. Maslov, Terence T. W. Wong, Lei Li, Chih-Hsien Huang, Jun Zou, and Lihong V. Wang. “High-speed label-free functional photoacoustic microscopy of mouse brain in action.” Nature Methods 12, no. 5 (May 2015): 407–10. https://doi.org/10.1038/nmeth.3336.Full Text Open Access Copy
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Yang, Joon-Mo, Chiye Li, Ruimin Chen, Bin Rao, Junjie Yao, Cheng-Hung Yeh, Amos Danielli, et al. “Optical-resolution photoacoustic endomicroscopy in vivo.” Biomedical Optics Express 6, no. 3 (March 2015): 918–32. https://doi.org/10.1364/boe.6.000918.Full Text
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Yang, Joon Mo, Christopher Favazza, Junjie Yao, Ruimin Chen, Qifa Zhou, K Kirk Shung, and Lihong V. Wang. “Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus.” Plos One 10, no. 4 (January 2015): e0120269. https://doi.org/10.1371/journal.pone.0120269.Full Text
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Martel, Catherine, Junjie Yao, Chih-Hsien Huang, Jun Zou, Gwendalyn J. Randolph, and Lihong V. Wang. “Photoacoustic lymphatic imaging with high spatial-temporal resolution.” Journal of Biomedical Optics 19, no. 11 (November 2014): 116009. https://doi.org/10.1117/1.jbo.19.11.116009.Full Text
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Hai, Pengfei, Junjie Yao, Konstantin I. Maslov, Yong Zhou, and Lihong V. Wang. “Near-infrared optical-resolution photoacoustic microscopy.” Optics Letters 39, no. 17 (September 2014): 5192–95. https://doi.org/10.1364/ol.39.005192.Full Text
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Yao, Junjie, Daria M. Shcherbakova, Chiye Li, Arie Krumholz, Ramon A. Lorca, Erin Reinl, Sarah K. England, Vladislav V. Verkhusha, and Lihong V. Wang. “Reversibly switchable fluorescence microscopy with enhanced resolution and image contrast.” Journal of Biomedical Optics 19, no. 8 (August 2014): 086018. https://doi.org/10.1117/1.jbo.19.8.086018.Full Text
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Zhang, Ruiying, Lidai Wang, Junjie Yao, Cheng-Hung Yeh, and Lihong V. Wang. “In vivo optically encoded photoacoustic flowgraphy.” Optics Letters 39, no. 13 (July 2014): 3814–17. https://doi.org/10.1364/ol.39.003814.Full Text
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Zhang, Yu Shrike, Junjie Yao, Chi Zhang, Lei Li, Lihong V. Wang, and Younan Xia. “Optical-resolution photoacoustic microscopy for volumetric and spectral analysis of histological and immunochemical samples.” Angewandte Chemie (International Ed. in English) 53, no. 31 (July 2014): 8099–8103. https://doi.org/10.1002/anie.201403812.Full Text
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Yao, Junjie, and Lihong V. Wang. “Sensitivity of photoacoustic microscopy.” Photoacoustics 2, no. 2 (June 2014): 87–101. https://doi.org/10.1016/j.pacs.2014.04.002.Full Text
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Yao, Junjie, and Lihong V. Wang. “Photoacoustic Brain Imaging: from Microscopic to Macroscopic Scales.” Neurophotonics 1, no. 1 (May 2014): 1877516. https://doi.org/10.1117/1.nph.1.1.011003.Full Text
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Yao, Junjie, Rebecca C. Gilson, Konstantin I. Maslov, Lidai Wang, and Lihong V. Wang. “Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media.” Journal of Biomedical Optics 19, no. 4 (April 2014): 046007. https://doi.org/10.1117/1.jbo.19.4.046007.Full Text
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Yao, Junjie, and Lihong V. Wang. “Breakthrough in Photonics 2013: Photoacoustic Tomography in Biomedicine.” Ieee Photonics Journal 6, no. 2 (April 2014): 0701006. https://doi.org/10.1109/jphot.2014.2310197.Full Text
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Zhou, Yong, Junjie Yao, Konstantin I. Maslov, and Lihong V. Wang. “Calibration-free absolute quantification of particle concentration by statistical analyses of photoacoustic signals in vivo.” Journal of Biomedical Optics 19, no. 3 (March 2014): 37001. https://doi.org/10.1117/1.jbo.19.3.037001.Full Text
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Xia, Jun, Junjie Yao, and Lihong V. Wang. “Photoacoustic tomography: principles and advances.” Electromagnetic Waves (Cambridge, Mass.) 147 (January 2014): 1–22. https://doi.org/10.2528/pier14032303.Full Text Open Access Copy
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Yao, Junjie, Lidai Wang, Chiye Li, Chi Zhang, and Lihong V. Wang. “Photoimprint photoacoustic microscopy for three-dimensional label-free subdiffraction imaging.” Physical Review Letters 112, no. 1 (January 2014): 014302. https://doi.org/10.1103/physrevlett.112.014302.Full Text
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Zhang, Yu Shrike, Junjie Yao, Lihong V. Wang, and Younan Xia. “Fabrication of Cell Patches Using Biodegradable Scaffolds with a Hexagonal Array of Interconnected Pores (SHAIPs).” Polymer 55, no. 1 (January 2014): 445–52. https://doi.org/10.1016/j.polymer.2013.06.019.Full Text
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Zhang, Yu Shrike, Xin Cai, Junjie Yao, Wenxin Xing, Lihong V. Wang, and Younan Xia. “Non-invasive and in situ characterization of the degradation of biomaterial scaffolds by volumetric photoacoustic microscopy.” Angewandte Chemie (International Ed. in English) 53, no. 1 (January 2014): 184–88. https://doi.org/10.1002/anie.201306282.Full Text
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Yao, Junjie, Haixin Ke, Stephen Tai, Yong Zhou, and Lihong V. Wang. “Absolute photoacoustic thermometry in deep tissue.” Optics Letters 38, no. 24 (December 2013): 5228–31. https://doi.org/10.1364/ol.38.005228.Full Text
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Wang, Lidai, Jun Xia, Junjie Yao, Konstantin I. Maslov, and Lihong V. Wang. “Ultrasonically encoded photoacoustic flowgraphy in biological tissue.” Physical Review Letters 111, no. 20 (November 2013): 204301. https://doi.org/10.1103/physrevlett.111.204301.Full Text
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Wang, Lidai, Junjie Yao, Konstantin I. Maslov, Wenxin Xing, and Lihong V. Wang. “Ultrasound-heated photoacoustic flowmetry.” Journal of Biomedical Optics 18, no. 11 (November 2013): 117003. https://doi.org/10.1117/1.jbo.18.11.117003.Full Text
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Yao, Junjie, and Lihong V. Wang. “Photoacoustic Microscopy.” Laser & Photonics Reviews 7, no. 5 (September 2013). https://doi.org/10.1002/lpor.201200060.Full Text
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Zhang, Ruiying, Junjie Yao, Konstantin I. Maslov, and Lihong V. Wang. “Structured-illumination photoacoustic Doppler flowmetry of axial flow in homogeneous scattering media.” Applied Physics Letters 103, no. 9 (August 2013): 94101. https://doi.org/10.1063/1.4819735.Full Text
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Zhou, Yong, Junjie Yao, and Lihong V. Wang. “Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth.” Optics Letters 38, no. 14 (July 2013): 2592–95. https://doi.org/10.1364/ol.38.002592.Full Text
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Rowland, Kathryn J., Junjie Yao, Lidai Wang, Christopher R. Erwin, Konstantin I. Maslov, Lihong V. Wang, and Brad W. Warner. “Up-regulation of hypoxia-inducible factor 1 alpha and hemodynamic responses following massive small bowel resection.” Journal of Pediatric Surgery 48, no. 6 (June 2013): 1330–39. https://doi.org/10.1016/j.jpedsurg.2013.03.031.Full Text
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Cai, Xin, Yu Zhang, Li Li, Sung-Wook Choi, Matthew R. MacEwan, Junjie Yao, Chulhong Kim, Younan Xia, and Lihong V. Wang. “Investigation of neovascularization in three-dimensional porous scaffolds in vivo by a combination of multiscale photoacoustic microscopy and optical coherence tomography.” Tissue Engineering. Part C, Methods 19, no. 3 (March 2013): 196–204. https://doi.org/10.1089/ten.tec.2012.0326.Full Text
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Huang, Chih-Hsien, Junjie Yao, Lihong V. Wang, and Jun Zou. “A water-immersible 2-axis scanning mirror microsystem for ultrasound andha photoacoustic microscopic imaging applications.” Microsystem Technologies : Sensors, Actuators, Systems Integration 19, no. 4 (January 2013): 577–82. https://doi.org/10.1007/s00542-012-1660-4.Full Text
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Yao, Junjie, Jun Xia, Konstantin I. Maslov, Mohammadreza Nasiriavanaki, Vassiliy Tsytsarev, Alexei V. Demchenko, and Lihong V. Wang. “Noninvasive photoacoustic computed tomography of mouse brain metabolism in vivo.” Neuroimage 64 (January 2013): 257–66. https://doi.org/10.1016/j.neuroimage.2012.08.054.Full Text
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Zhang, Chi, Konstantin Maslov, Junjie Yao, and Lihong V. Wang. “In vivo photoacoustic microscopy with 7.6-µm axial resolution using a commercial 125-MHz ultrasonic transducer.” Journal of Biomedical Optics 17, no. 11 (November 2012): 116016. https://doi.org/10.1117/1.jbo.17.11.116016.Full Text
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Yang, Joon-Mo, Ruimin Chen, Christopher Favazza, Junjie Yao, Chiye Li, Zhilin Hu, Qifa Zhou, K Kirk Shung, and Lihong V. Wang. “A 2.5-mm diameter probe for photoacoustic and ultrasonic endoscopy.” Optics Express 20, no. 21 (October 2012): 23944–53. https://doi.org/10.1364/oe.20.023944.Full Text
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Yang, Joon-Mo, Christopher Favazza, Ruimin Chen, Junjie Yao, Xin Cai, Konstantin Maslov, Qifa Zhou, K Kirk Shung, and Lihong V. Wang. “Simultaneous functional photoacoustic and ultrasonic endoscopy of internal organs in vivo.” Nature Medicine 18, no. 8 (August 2012): 1297–1302. https://doi.org/10.1038/nm.2823.Full Text
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Yao, Junjie, Chih-Hsien Huang, Lidai Wang, Joon-Mo Yang, Liang Gao, Konstantin I. Maslov, Jun Zou, and Lihong V. Wang. “Wide-field fast-scanning photoacoustic microscopy based on a water-immersible MEMS scanning mirror.” Journal of Biomedical Optics 17, no. 8 (August 2012): 080505–080501. https://doi.org/10.1117/1.jbo.17.8.080505.Full Text
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Yao, Junjie, Konstantin I. Maslov, and Lihong V. Wang. “In vivo photoacoustic tomography of total blood flow and potential imaging of cancer angiogenesis and hypermetabolism.” Technology in Cancer Research & Treatment 11, no. 4 (August 2012): 301–7. https://doi.org/10.7785/tcrt.2012.500278.Full Text
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Krumholz, Arie, Lidai Wang, Junjie Yao, and Lihong V. Wang. “Functional photoacoustic microscopy of diabetic vasculature.” Journal of Biomedical Optics 17, no. 6 (June 2012): 060502. https://doi.org/10.1117/1.jbo.17.6.060502.Full Text
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Rowland, Kathryn J., Junjie Yao, Lidai Wang, Christopher R. Erwin, Konstantin I. Maslov, Lihong V. Wang, and Brad W. Warner. “Immediate alterations in intestinal oxygen saturation and blood flow after massive small bowel resection as measured by photoacoustic microscopy.” Journal of Pediatric Surgery 47, no. 6 (June 2012): 1143–49. https://doi.org/10.1016/j.jpedsurg.2012.03.020.Full Text
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Filonov, Grigory S., Arie Krumholz, Jun Xia, Junjie Yao, Lihong V. Wang, and Vladislav V. Verkhusha. “Deep-tissue photoacoustic tomography of a genetically encoded near-infrared fluorescent probe.” Angewandte Chemie (International Ed. in English) 51, no. 6 (February 2012): 1448–51. https://doi.org/10.1002/anie.201107026.Full Text
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Yao, Junjie, Konstantin I. Maslov, Ernest R. Puckett, Kathryn J. Rowland, Brad W. Warner, and Lihong V. Wang. “Double-illumination photoacoustic microscopy.” Optics Letters 37, no. 4 (February 2012): 659–61. https://doi.org/10.1364/ol.37.000659.Full Text
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Tsytsarev, Vassiliy, Konstantin I. Maslov, Junjie Yao, Archana R. Parameswar, Alexei V. Demchenko, and Lihong V. Wang. “In vivo imaging of epileptic activity using 2-NBDG, a fluorescent deoxyglucose analog.” Journal of Neuroscience Methods 203, no. 1 (January 2012): 136–40. https://doi.org/10.1016/j.jneumeth.2011.09.005.Full Text
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Chatni, Muhammad Rameez, Junjie Yao, Amos Danielli, Christopher P. Favazza, Konstantin I. Maslov, and Lihong V. Wang. “Functional photoacoustic microscopy of pH.” Journal of Biomedical Optics 16, no. 10 (October 2011): 100503. https://doi.org/10.1117/1.3644495.Full Text
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Yao, Junjie, and Lihong V. Wang. “Photoacoustic tomography: fundamentals, advances and prospects.” Contrast Media & Molecular Imaging 6, no. 5 (September 2011): 332–45. https://doi.org/10.1002/cmmi.443.Full Text
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Krumholz, Arie, Sarah J. Vanvickle-Chavez, Junjie Yao, Timothy P. Fleming, William E. Gillanders, and Lihong V. Wang. “Photoacoustic microscopy of tyrosinase reporter gene in vivo.” Journal of Biomedical Optics 16, no. 8 (August 2011): 080503. https://doi.org/10.1117/1.3606568.Full Text
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Oladipupo, Sunday, Song Hu, Joanna Kovalski, Junjie Yao, Andrea Santeford, Rebecca E. Sohn, Ralph Shohet, Konstantin Maslov, Lihong V. Wang, and Jeffrey M. Arbeit. “VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting.” Proceedings of the National Academy of Sciences of the United States of America 108, no. 32 (August 2011): 13264–69. https://doi.org/10.1073/pnas.1101321108.Full Text
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Tsytsarev, Vassiliy, Song Hu, Junjie Yao, Konstantin Maslov, Dennis L. Barbour, and Lihong V. Wang. “Photoacoustic microscopy of microvascular responses to cortical electrical stimulation.” Journal of Biomedical Optics 16, no. 7 (July 2011): 076002. https://doi.org/10.1117/1.3594785.Full Text
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Yao, Junjie, Konstantin I. Maslov, Yu Zhang, Younan Xia, and Lihong V. Wang. “Label-free oxygen-metabolic photoacoustic microscopy in vivo.” Journal of Biomedical Optics 16, no. 7 (July 2011): 076003. https://doi.org/10.1117/1.3594786.Full Text
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Oladipupo, Sunday S., Song Hu, Andrea C. Santeford, Junjie Yao, Joanna R. Kovalski, Ralph V. Shohet, Konstantin Maslov, Lihong V. Wang, and Jeffrey M. Arbeit. “Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.” Blood 117, no. 15 (April 2011): 4142–53. https://doi.org/10.1182/blood-2010-09-307538.Full Text
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Kim, Chulhong, Hyon-Min Song, Xin Cai, Junjie Yao, Alexander Wei, and Lihong V. Wang. “In vivo photoacoustic mapping of lymphatic systems with plasmon-resonant nanostars.” Journal of Materials Chemistry 21, no. 9 (January 2011): 2841–44. https://doi.org/10.1039/c0jm04194g.Full Text
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Wang, Lidai, Konstantin Maslov, Junjie Yao, Bin Rao, and Lihong V. Wang. “Fast voice-coil scanning optical-resolution photoacoustic microscopy.” Optics Letters 36, no. 2 (January 2011): 139–41. https://doi.org/10.1364/ol.36.000139.Full Text
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Yao, Junjie, Konstantin I. Maslov, Yunfei Shi, Larry A. Taber, and Lihong V. Wang. “In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth.” Optics Letters 35, no. 9 (May 2010): 1419–21. https://doi.org/10.1364/ol.35.001419.Full Text
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Yao, Junjie, and Lihong V. Wang. “Transverse flow imaging based on photoacoustic Doppler bandwidth broadening.” Journal of Biomedical Optics 15, no. 2 (March 2010): 021304. https://doi.org/10.1117/1.3339953.Full Text
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Yao, Junjie, Konstantin Maslov, Song Hu, and Lihong V. Wang. “Evans blue dye-enhanced capillary-resolution photoacoustic microscopy in vivo.” Journal of Biomedical Optics 14, no. 5 (September 2009): 054049. https://doi.org/10.1117/1.3251044.Full Text
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Song, X. L., G. Hu, J. J. Yao, and J. Bai. “Three-dimensional reconstruction for fluorescence tomography using cylinder phantoms.” Ruan Jian Xue Bao/Journal of Software 20, no. 5 (May 1, 2009): 1089–95. https://doi.org/10.3724/SP.J.1001.2009.03560.Full Text
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Yao, J. J., G. Hu, and J. Bai. “Modeling and validation of light propagation in free-space for non-contact near-infrared fluorescent tomography.” Hongwai Yu Haomibo Xuebao/Journal of Infrared and Millimeter Waves 27, no. 5 (October 1, 2008).
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Yao, J. J., G. Hu, S. H. Yue, and J. Bai. “A 3D-surface torso reconstruction method used in fluorescence molecular tomography of small animals.” Chinese Journal of Biomedical Engineering 27, no. 3 (June 1, 2008): 360–65.
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Hu, G., J. Yao, and J. Bai. “Full-angle optical imaging of near-infrared fluorescent probes implanted in small animals.” Progress in Natural Science 18, no. 6 (January 1, 2008): 707–11. https://doi.org/10.1016/j.pnsc.2007.11.021.Full Text
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Book Sections
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Yao, J., and L. V. Wang. “Photoacoustic Molecular Imaging: Principles and Practice.” In Molecular Imaging: Principles and Practice, 233–44, 2021. https://doi.org/10.1016/B978-0-12-816386-3.00016-8.Full Text
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Vienneau, E., T. Vu, and J. Yao. “Photoacoustic imaging of skin.” In Imaging Technologies and Transdermal Delivery in Skin Disorders, 411–42, 2019. https://doi.org/10.1002/9783527814633.ch16.Full Text
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Vienneau, E., T. Vu, and J. Yao. “Photoacoustic imaging of skin.” In Augmented Customer Strategy: CRM in the Digital Age, 411–42, 2019.
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Wang, L. V., J. Xia, and J. Yao. “Photoacoustic neuroimaging.” In Neurophotonics and Brain Mapping, 235–56, 2017. https://doi.org/10.1201/9781315373058.Full Text
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Zhou, M., L. Li, J. Yao, R. R. Bouchard, L. V. Wang, and C. Li. “Nanoparticles for photoacoustic imaging of vasculature.” In Design and Applications of Nanoparticles in Biomedical Imaging, 337–56, 2016. https://doi.org/10.1007/978-3-319-42169-8_16.Full Text
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Conference Papers
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Wu, H., Y. Tang, H. Kim, J. Yao, and X. Jiang. “Fiber based laser ultrasound transducer for intravascular thrombolysis with detective photoacoustic imaging.” In Ieee International Ultrasonics Symposium, Ius, Vol. 2020-September, 2020. https://doi.org/10.1109/IUS46767.2020.9251732.Full Text
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Li, M., and J. Yao. “Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-scattering Fiber Diffuser.” In 2020 Ieee Photonics Conference, Ipc 2020 Proceedings, 2020. https://doi.org/10.1109/IPC47351.2020.9252241.Full Text
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Yao, J. “Ultrasfast Wide-field Photoacoustic Microscopy of Small-animal Models.” In 2020 Ieee Photonics Conference, Ipc 2020 Proceedings, 2020. https://doi.org/10.1109/IPC47351.2020.9252208.Full Text
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Nief, Corrine A., Erika Chelales, Robert Morhard, Maomao Chem, Jeffrey Everitt, Jenna Mueller, Junjie Yao, Mark W. Dewhirst, and Nirmala Ramanujam. “Abstract 5243: Averting tumor growth in rodent breast cancer models with a liquid ablation approach.” In Cancer Research, 80:5243–5243. American Association for Cancer Research (AACR), 2020. https://doi.org/10.1158/1538-7445.am2020-5243.Full Text
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Wu, H., H. Kim, Y. Tang, J. Yao, and X. Jiang. “Fiber-optic laser-ultrasound transducer using carbon nanoparticles for intravascular sonothrombolysis.” In Proceedings of the Ieee Conference on Nanotechnology, 2019-July:261–64, 2019. https://doi.org/10.1109/NANO46743.2019.8993894.Full Text
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Duan, T., Y. Tang, F. Gao, and J. Yao. “Application of mathematical morphological filter for noise reduction in photoacoustic imaging.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10878, 2019. https://doi.org/10.1117/12.2512176.Full Text
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Li, L., A. A. Shemetov, P. Hu, D. M. Shcherbakova, J. Shi, J. Yao, V. V. Verkhusha, and L. V. Wang. “In vivo photoacoustic multi-contrast imaging and detection of protein interactions using a small near-infrared photochromic protein.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10878, 2019. https://doi.org/10.1117/12.2509198.Full Text
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Lan, B., W. Liu, and J. Yao. “High-speed wide-field photoacoustic microscopy.” In Optics Infobase Conference Papers, Vol. Part F91-TRANSLATIONAL 2018, 2018. https://doi.org/10.1364/TRANSLATIONAL.2018.JTu3A.68.Full Text
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Yao, J., J. Zou, and L. V. Wang. “Wide-field fast-scanning photoacoustic microscopy of brain functions in action.” In 2017 Conference on Lasers and Electro Optics, Cleo 2017 Proceedings, 2017-January:1–2, 2017. https://doi.org/10.1364/CLEO_AT.2017.ATu1B.5.Full Text
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He, Y., L. Wang, J. Shi, J. Yao, L. Li, R. Zhang, C. H. Huang, J. Zou, and L. V. Wang. “Real-time photoacoustic flow cytography and photothermolysis of single circulating melanoma cells in vivo.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10064, 2017. https://doi.org/10.1117/12.2255068.Full Text
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Li, L., L. Zhu, C. Ma, L. Lin, J. Yao, L. Wang, K. Maslov, et al. “Imaging small animal whole-body dynamics by single-impulse panoramic photoacoustic computed tomography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10064, 2017. https://doi.org/10.1117/12.2251593.Full Text
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Yao, J., A. A. Kaberniuk, L. Li, D. M. Shcherbakova, R. Zhang, L. Wang, G. Li, V. V. Verkhusha, and L. V. Wanga. “Reversibly switchable photoacoustic tomography using a genetically encoded near-infrared phytochrome.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9708, 2016. https://doi.org/10.1117/12.2229156.Full Text
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Yao, J., J. M. Yang, L. Waiig, J. Zou, and L. Y. Waug. “Fast functional photoacoustic microscopy of mouse brain.” In Optics and the Brain, Brain 2015, 2015. https://doi.org/10.1364/brain.2015.brm4b.3.Full Text
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Wang, L., J. Yao, R. Zhang, S. Xu, G. Li, J. Zou, and L. V. Wang. “Photoacoustic imaging of single circulating melanoma cells in vivo.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9323, 2015. https://doi.org/10.1117/12.2076987.Full Text
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Yang, J. M., C. Favazza, J. Yao, R. Chen, Q. Zhou, K. K. Shung, and L. V. Wang. “Three-dimensional photoacoustic and ultrasonic endoscopic imaging of two rabbit esophagi.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9323, 2015. https://doi.org/10.1117/12.2080294.Full Text
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Yang, J. M., C. Li, R. Chen, B. Rao, J. Yao, C. H. Yeh, A. Danielli, et al. “Label-free optical-resolution photoacoustic endomicroscopy in vivo.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9323, 2015. https://doi.org/10.1117/12.2080224.Full Text
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Yao, J., J. M. Yang, L. Waiig, J. Zou, and L. Y. Waug. “Fast functional photoacoustic microscopy of mouse brain.” In Optics and the Brain, Brain 2015, 2015.
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Yao, J., L. Wang, C. Li, C. Zhang, and L. V. Wang. “Photo-imprint super-resolution photoacoustic microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9323, 2015. https://doi.org/10.1117/12.2077350.Full Text
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Yang, Zhenyuan, Jianhua Chen, Junjie Yao, Riqiang Lin, Jing Meng, Chengbo Liu, Jinhua Yang, Xiang Li, Lihong Wang, and Liang Song. “Multi-parametric quantitative microvascular imaging with optical-resolution photoacoustic microscopy in vivo.” In Optics Express, 22:1500–1511, 2014. https://doi.org/10.1364/oe.22.001500.Full Text
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Zhang, R., J. Yao, K. I. Maslov, and L. V. Wang. “Photoacoustic Doppler axial flow measurement of homogenous media using structured illumination.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8943, 2014. https://doi.org/10.1117/12.2038356.Full Text
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Zhou, Y., J. Yao, K. I. Maslov, and L. V. Wang. “Photoacoustic correlation spectroscopy for calibration-free absolute quantification of particle concentration.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8943, 2014. https://doi.org/10.1117/12.2036635.Full Text
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Zhou, Y., J. Yao, and L. V. Wang. “Photoacoustic microscopy with enhanced resolution and imaging depth aided by optical clearing.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8943, 2014. https://doi.org/10.1117/12.2036636.Full Text
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Huang, C. H., J. Yao, L. V. Wang, and J. Zou. “A water-immersible 2-Axis scanning mirror microsystem for ultrasound and photoacoustic microscopic imaging applications.” In Proceedings of Spie the International Society for Optical Engineering, Vol. 8616, 2013. https://doi.org/10.1117/12.2003087.Full Text
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Cai, X., Y. Zhang, L. Li, S. W. Choi, M. R. MacEwan, J. Yao, C. Kim, Y. Xia, and L. V. Wang. “Photoacoustic microscopy of neovascularization in three-dimensional porous scaffolds.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8581, 2013. https://doi.org/10.1117/12.2005236.Full Text
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Yang, J. M., C. Favazza, R. Chen, J. Yao, X. Cai, C. Li, K. Maslov, Q. Zhou, K. K. Shung, and L. V. Wang. “Photoacoustic endoscopic imaging of the rabbit mediastinum.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8581, 2013. https://doi.org/10.1117/12.2004980.Full Text
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Yao, J., C. H. Huang, C. Martel, K. I. Maslov, L. Wang, J. M. Yang, L. Gao, G. Randolph, J. Zou, and L. V. Wang. “Water-Immersible MEMS scanning mirror designed for wide-field fast-scanning photoacoustic microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8581, 2013. https://doi.org/10.1117/12.2005669.Full Text
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Yao, J., J. Xia, K. Maslov, M. R. N. Avanaki, V. Tsytsarev, A. V. Demchenko, and L. V. Wang. “Noninvasive photoacoustic computed tomography of mouse brain metabolism in vivo.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8581, 2013. https://doi.org/10.1117/12.2005645.Full Text
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Zhang, C., K. Maslov, J. Yao, and L. V. Wang. “Photoacoustic microscopy with 7.6-μm axial resolution.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8581, 2013. https://doi.org/10.1117/12.2003248.Full Text
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Yao, J., and L. V. Wang. “Multi-scale Multi-contrast Photoacoustic Microscopy.” In Optics Infobase Conference Papers, 2013.
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Yao, J., and L. V. Wang. “Multi-scale Multi-contrast Photoacoustic Microscopy.” In Optics Infobase Conference Papers, 2013. https://doi.org/10.1364/fio.2013.fm4a.1.Full Text
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Yang, J. M., C. Favazza, R. Chen, J. Yao, X. Cai, K. Maslov, Q. Zhou, K. Kirk Shung, and L. V. Wang. “Volumetric photoacoustic endoscopy.” In Biomedical Optics, Biomed 2012, 2012.
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Chatni, M. R., J. Yao, A. Danielli, C. P. Favazza, K. I. Maslov, and L. V. Wang. “Functional photoacoustic microscopy of pH.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8223, 2012. https://doi.org/10.1117/12.907685.Full Text
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Hu, S., R. Sohn, Z. H. Lu, B. Soetikno, Q. Zhong, J. Yao, K. Maslov, J. M. Arbeit, and L. V. Wang. “Multi-contrast photoacoustic microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8223, 2012. https://doi.org/10.1117/12.909754.Full Text
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Krumholz, A., G. S. Filonov, J. Xia, J. Yao, V. V. Verkhusha, and L. V. Wang. “Photoacoustic imaging of the near-infrared fluorescent protein iRFP in vivo.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8223, 2012. https://doi.org/10.1117/12.908927.Full Text
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Yang, J. M., C. Favazza, R. Chen, J. Yao, X. Cai, K. Maslov, Q. Zhou, K. K. Shung, and L. V. Wang. “Toward dual-wavelength functional photoacoustic endoscopy: Laser and peripheral optical systems development.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8223, 2012. https://doi.org/10.1117/12.909163.Full Text
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Yang, J. M., R. Chen, C. Favazza, J. Yao, Q. Zhou, K. K. Shung, and L. V. Wang. “A 2.5-mm outer diameter photoacoustic endoscopic mini-probe based on a highly sensitive PMN-PT ultrasonic transducer.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8223, 2012. https://doi.org/10.1117/12.909207.Full Text
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Yao, J., K. I. Maslov, and L. V. Wang. “In vivo photoacoustic tomography of total blood flow and Doppler angle.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8223, 2012. https://doi.org/10.1117/12.909480.Full Text
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Yao, J., K. J. Rowland, L. Wang, K. I. Maslov, B. W. Warner, and L. V. Wang. “Double-illumination photoacoustic microscopy of intestinal hemodynamics following massive small bowel resection.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8223, 2012. https://doi.org/10.1117/12.909508.Full Text
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Yao, J., C. H. Huang, K. I. Maslov, L. Wang, L. Gao, J. Zou, and L. V. Wang. “Water-Immersible MEMS scanning mirror enhanced optical-resolution photoacoustic microscopy.” In Biomedical Optics, Biomed 2012, 2012. https://doi.org/10.1364/biomed.2012.bsu3a.54.Full Text
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Danielli, A., J. Yao, A. Krumholz, and L. V. Wang. “Effects of calibration factors and intensity dependent non-linearity on functional photoacoustic microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7899, 2011. https://doi.org/10.1117/12.875287.Full Text
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Krumholz, A., S. Chavez, J. Yao, T. Fleming, W. E. Gillanders, and L. V. Wang. “Tyrosinase-catalyzed melanin as a contrast agent for photoacoustic tomography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7899, 2011. https://doi.org/10.1117/12.879110.Full Text
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Wang, L., K. Maslov, J. Yao, L. Li, and L. V. Wang. “Development of real-time photoacoustic microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7899, 2011. https://doi.org/10.1117/12.875415.Full Text
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Yao, J., K. I. Maslov, and L. V. Wang. “Noninvasive quantification of metabolic rate of oxygen (MRO2) by photoacoustic microscopy.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7899, 2011. https://doi.org/10.1117/12.874777.Full Text
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Rao, B., X. Cai, F. Christopher, J. Yao, L. Li, S. Duong, L. H. Liaw, J. Holtzman, P. Wilder-Smith, and L. V. Wang. “Photoacoustic microscopy of human teeth.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7884, 2011. https://doi.org/10.1117/12.874070.Full Text
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Hu, S., S. Oladipupo, J. Yao, A. C. Santeford, K. Maslov, J. Kovalski, J. M. Arbeit, and L. V. Wang. “Optical-resolution photoacoustic microscopy of angiogenesis in a transgenic mouse model.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7564, 2010. https://doi.org/10.1117/12.841177.Full Text
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Tsytsarev, V., J. Yao, S. Hu, L. Li, C. P. Favazza, K. I. Maslov, and L. V. Wang. “Invasive and transcranial photoacoustic imaging of the vascular response to brain electrical stimulation.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7564, 2010. https://doi.org/10.1117/12.840290.Full Text
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Yao, J., K. I. Maslov, S. Hu, and L. V. Wang. “Photoacoustic microscopy using Evans Blue dye as a contrast agent.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7564, 2010. https://doi.org/10.1117/12.840684.Full Text
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Yao, J., K. I. Maslov, and L. V. Wang. “Transverse flow measurement using photoacoustic Doppler bandwidth broadening: Phantom and in vivo studies.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7564, 2010. https://doi.org/10.1117/12.840676.Full Text
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Hu, G., J. Yao, H. Li, and J. Bai. “Fluorescent optical imaging of small animals using filtered back-projection 3D surface reconstruction method.” In Biomedical Engineering and Informatics: New Development and the Future Proceedings of the 1st International Conference on Biomedical Engineering and Informatics, Bmei 2008, 2:76–80, 2008. https://doi.org/10.1109/BMEI.2008.61.Full Text
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Preprints
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Zhang, Wenxu, Yajuan Li, Anthony A. Fung, Zhi Li, Hongje Jang, Honghao Zha, Xiaoping Chen, et al. “Multi-Molecular Hyperspectral PRM-SRS Imaging.” Cold Spring Harbor Laboratory, July 25, 2022. https://doi.org/10.1101/2022.07.25.501472.Full Text
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- Teaching & Mentoring
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Recent Courses
- BME 494: Projects in Biomedical Engineering (GE) 2023
- BME 553: Deep Tissue Optics (GE, IM) 2023
- BME 791: Graduate Independent Study 2023
- BME 303L: Modern Diagnostic Imaging Systems (AC or GE) 2022
- BME 493: Projects in Biomedical Engineering (GE) 2022
- BME 590: Special Topics in Biomedical Engineering 2022
- BME 790L: Advanced Topics with the Lab for Graduate Students in Biomedical Engineering 2022
- BME 791: Graduate Independent Study 2022
- BME 792: Continuation of Graduate Independent Study 2022
- BME 303L: Modern Diagnostic Imaging Systems (AC or GE) 2021
- BME 590: Special Topics in Biomedical Engineering 2021
- BME 790L: Advanced Topics with the Lab for Graduate Students in Biomedical Engineering 2021
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Advising & Mentoring
Available to mentor:
- Masters
- PhD
- Post-Doc
- Professional
- Undergraduate
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