Scholars@Duke
Justin Solomon

Justin Solomon

Associate Professor of Radiology
Radiology
justin.solomon@duke.edu
2424 Erwin Rd, Suite 302, Office 3050, Durham, NC 27705
2424 Erwin Rd, Suite 302 Office 3005, Durham, NC 27705

Scholarly Works - Conferences

A Data-Centric Strategy for Developing CT Dose and Noise Reference Levels from Clinical Patient Populations

Conference · November 27, 2018 PURPOSE To develop a data-centric strategy solution for developing CT dose and noise reference levels across large clinical patient populations and in CT scanners. METHOD AND MATERIALS This IRB-exempt study evaluated CT abdominopelvic (AP)-related examin ... Cite

3D printed anthropomorphic physical phantom for mammography and DBT with high contrast custom materials, lesions, and uniform chest wall region

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2018 Anthropomorphic breast phantoms mimic anatomy to evaluate the performance of clinical mammography and digital breast tomosynthesis (DBT) systems. Our goal is to make a phantom that mimics clinically relevant appearance of a patient to allow for improved im ... Full text Cite

How reliable are texture measurements?

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2018 The purpose of this study was to assess the bias (objectivity) and variability (robustness) of computed tomography (CT) texture features (internal heterogeneities) across a series of image acquisition settings and reconstruction algorithms. We simulated a ... Full text Cite

Realistic lesion simulation: Application of hyperelastic deformation to lesion-local environment in lung CT

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2018 Lesion simulation programs can be used to insert realistic, generated lesions into anatomical images for further study. Most lesion simulation programs rely on insertion of a mask within an otherwise unchangeable, i.e., static surrounding - in reality, les ... Full text Cite

Bias and variability in morphology features of lung lesions across CT imaging conditions

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2018 CT imaging method can influence radiomic features. The purpose of this study was to characterize the intra-protocol and inter-protocol variability and bias of quantitative morphology features of lung lesions across a range of CT imaging conditions. A total ... Full text Cite

Can a 3D task transfer function accurately represent the signal transfer properties of low-contrast lesions in non-linear CT systems?

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2018 The purpose of this study was to investigate how accurately the task-transfer function (TTF) models the signal transfer properties of low-contrast features in a non-linear CT system. A cylindrical phantom containing 24 anthropomorphic liver lesions (modele ... Full text Cite

Quantifying quality: correlation phantom and clinical scan CT noise levels to contruct a Quality Reference Level

Conference · November 26, 2017 Conclusion This study represents a proof of concept method to develop and refine a Noise Reference Level for a given protocol and scanner. This represents a first step in establishing an automated Performance Reference Level for a given scan protocol that ... Cite

From DRL to NRL: A First Step Toward Quality-Based Reference Level

Conference Medical Physics · June 30, 2017 Purpose: Radiologic procedures are optimized based on a benefit-to-risk. However, risk has been the primary focus of radiology optimization and dose monitoring. Such programs are typically based on the concept of Diagnostic Reference Level (DRL). The term ... Cite

Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2017 Physical breast phantoms provide a standard method to test, optimize, and develop clinical mammography systems, including new digital breast tomosynthesis (DBT) systems. In previous work, we produced an anthropomorphic phantom based on 500x500x500 μm breas ... Full text Cite

Accuracy and variability of texture-based radiomics features of lung lesions across CT imaging conditions

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2017 Texture analysis for lung lesions is sensitive to changing imaging conditions but these effects are not well understood, in part, due to a lack of ground-truth phantoms with realistic textures. The purpose of this study was to explore the accuracy and vari ... Full text Cite

Development of local complexity metrics to quantify the effect of anatomical noise on detectability of lung nodules in chest CT imaging

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2017 The purpose of this study was to develop metrics of local anatomical complexity and compare them with detectability of lung nodules in CT. Data were drawn retrospectively from a published perception experiment in which detectability was assessed in cases e ... Full text Cite

In-vivo detectability index: Development and validation of an automated methodology

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2017 The purpose of this study was to develop and validate a method to estimate patient-specific detectability indices directly from patients' CT images (i.e., "in vivo"). The method works by automatically extracting noise (NPS) and resolution (MTF) properties ... Full text Cite

Inter-algorithm lesion volumetry comparison of real and 3D simulated lung lesions in CT

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2017 The purpose of this study was to establish volumetric exchangeability between real and computational lung lesions in CT. We compared the overall relative volume estimation performance of segmentation tools when used to measure real lesions in actual patien ... Full text Cite

Design, fabrication, and implementation of voxel-based 3D printed textured phantoms for task-based image quality assessment in CT

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2016 In x-ray computed tomography (CT), task-based image quality studies are typically performed using uniform background phantoms with low-contrast signals. Such studies may have limited clinical relevancy for modern non-linear CT systems due to possible influ ... Full text Cite

Second generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and inkjet printing of iodinated lesion inserts

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2016 Physical phantoms are needed for the evaluation and optimization of new digital breast tomosynthesis (DBT) systems. Previously, we developed an anthropomorphic phantom based on human subject breast CT data and fabricated using commercial 3D printing. We no ... Full text Cite

Development of a Hausdorff distance based 3D quantification technique to evaluate the CT imaging system impact on depiction of lesion morphology

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2016 The purpose of this study was to develop a 3D quantification technique to assess the impact of imaging system on depiction of lesion morphology. Regional Hausdorff Distance (RHD) was computed from two 3D volumes: virtual mesh models of synthetic nodules or ... Full text Cite

Development and comparison of projection and image space 3D nodule insertion techniques

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2016 This study aimed to develop and compare two methods of inserting computerized virtual lesions into CT datasets. 24 physical (synthetic) nodules of three sizes and four morphologies were inserted into an anthropomorphic chest phantom (LUNGMAN, KYOTO KAGAKU) ... Full text Cite

Synthesized interstitial lung texture for use in anthropomorphic computational phantoms

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2016 A realistic model of the anatomical texture from the pulmonary interstitium was developed with the goal of extending the capability of anthropomorphic computational phantoms (e.g., XCAT, Duke University), allowing for more accurate image quality assessment ... Full text Cite

A multireader diagnostic performance study of low-contrast detectability on a third-generation dual-source CT scanner: Filtered back projection versus advanced modeled iterative reconstruction

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2015 The purpose of this work was to compare CT low-contrast detectability between two reconstruction algorithms, filtered back-projection (FBP) and advanced modeled iterative reconstruction (ADMIRE). A phantom was designed with a range of low-contrast circular ... Full text Cite

What observer models best reflect low-contrast detectability in CT?

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2015 The purpose of this work was to compare CT low-contrast detectability as measured via human perception experiments with observer model surrogates of image quality measured directly from the images. A phantom was designed with a range of low-contrast circul ... Full text Cite

Are uniform phantoms sufficient to characterize the performance of iterative reconstruction in CT?

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · June 3, 2013 The evaluation of dose reduction potential from iterative reconstruction (IR) algorithms is an area of ongoing research in CT. The non-linearity of IR algorithms poses challenges to using traditional image quality metrics. Past attempts to evaluate iterati ... Full text Cite

TU‐C‐103‐01: A Framework for 3D Modeling of Anthropomorphic Lesions in CT

Conference Medical Physics · January 1, 2013 Purpose: Realistic three‐dimensional mathematical models of subtle lesions are essential for many CT studies focused on performance evaluation and optimization. The purpose of this work was to develop and apply a generic framework for creating such models ... Full text Cite