Justin Solomon

Journal article Phys Med · August 2025 PURPOSE: To develop and characterize individualized dose and quality measures at organ level compared to their generic counterparts across a clinical CT dataset. MATERIALS AND METHODS: The study included 9801 chest-abdomen-pelvis and abdomen-pelvis CT exam ... Full text Open Access Link to item Cite

Minimum perceivable size difference: how well can radiologists visually detect a change in lung nodule size from CT images?

Journal article Eur Radiol · April 2021 OBJECTIVE: The purpose of this study was to determine how well radiologists could visually detect a change in lung nodule size on the basis of visual image perception alone. SUBJECTS AND METHODS: Under IRB approval, 109 standard chest CT image series were ... Full text Link to item Cite

Can Realistic Liver Tissue Surrogates Accurately Quantify the Impact of Reduced-kV Imaging on Attenuation and Contrast of Parenchyma and Lesions?

Journal article Acad Radiol · May 2019 RATIONALE AND OBJECTIVES: To assess if a liquid tissue surrogate for the liver (LTSL) can emulate contrast-enhanced liver parenchyma and lesions and quantify the impact of reduced-kV imaging as a function of lesion contrast, phase of enhancement, and phant ... Full text Link to item Cite

How accurate and precise are CT based measurements of iodine concentration? A comparison of the minimum detectable concentration difference among single source and dual source dual energy CT in a phantom study.

Journal article Eur Radiol · April 2019 OBJECTIVES: To assess the impact of scan- and patient-related factors on the error and the minimum detectable difference in iodine concentration among different generations of single-source (SS) fast kV-switching and dual-source (DS) dual-energy CT (DECT). ... Full text Link to item Cite

Validation of lesion simulations in clinical CT data for anonymized chest and abdominal CT databases.

Journal article Med Phys · April 2019 PURPOSE: To make available to the medical imaging community a computed tomography (CT) image database composed of hybrid datasets (patient CT images with digitally inserted anthropomorphic lesions) where lesion ground truth is known a priori. It is envisio ... Full text Link to item Cite

High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study.

Journal article AJR Am J Roentgenol · March 2019 OBJECTIVE: The purpose of this study was to assess the impact of high pitch values on image noise, spatial resolution, and iodine quantification in single-source wide-coverage fast-kilovoltage-switching dual-energy CT (DECT). MATERIALS AND METHODS: Two pha ... Full text Link to item Cite

Systematic analysis of bias and variability of morphologic features for lung lesions in computed tomography.

Journal article J Med Imaging (Bellingham) · January 2019 We propose to characterize the bias and variability of quantitative morphology features of lung lesions across a range of computed tomography (CT) imaging conditions. A total of 15 lung lesions were simulated (five in each of three spiculation classes: low ... Full text Link to item Cite

3D task-transfer function representation of the signal transfer properties of low-contrast lesions in FBP- and iterative-reconstructed CT.

Journal article Med Phys · November 2018 PURPOSE: The purpose of this study was to investigate how accurately the task-transfer function (TTF) models the signal transfer properties of low-contrast features in a non-linear commercial CT system. METHODS: A cylindrical phantom containing 24 anthropo ... Full text Link to item Cite

Local complexity metrics to quantify the effect of anatomical noise on detectability of lung nodules in chest CT imaging.

Journal article J Med Imaging (Bellingham) · October 2018 The purpose of this study is to (1) develop metrics to characterize the regional anatomical complexity of the lungs, and (2) relate these metrics with lung nodule detection in chest CT. A free-scrolling reader-study with virtually inserted nodules (13 radi ... Full text Link to item Cite

Estimating detectability index in vivo: development and validation of an automated methodology.

Journal article J Med Imaging (Bellingham) · July 2018 This study's purpose was to develop and validate a method to estimate patient-specific detectability indices directly from patients' CT images (i.e., in vivo). The method extracts noise power spectrum (NPS) and modulation transfer function (MTF) resolution ... Full text Link to item Cite

Inter-laboratory comparison of channelized hotelling observer computation.

Journal article Med Phys · July 2018 PURPOSE: The task-based assessment of image quality using model observers is increasingly used for the assessment of different imaging modalities. However, the performance computation of model observers needs standardization as well as a well-established t ... Full text Link to item Cite

Interchangeability between real and three-dimensional simulated lung tumors in computed tomography: an interalgorithm volumetry study.

Journal article J Med Imaging (Bellingham) · July 2018 Using hybrid datasets consisting of patient-derived computed tomography (CT) images with digitally inserted computational tumors, we establish volumetric interchangeability between real and computational lung tumors in CT. Pathologically-confirmed malignan ... Full text Link to item Cite

A Third-Generation Adaptive Statistical Iterative Reconstruction Technique: Phantom Study of Image Noise, Spatial Resolution, Lesion Detectability, and Dose Reduction Potential.

Journal article AJR Am J Roentgenol · June 2018 OBJECTIVE: The purpose of this study was to assess image noise, spatial resolution, lesion detectability, and the dose reduction potential of a proprietary third-generation adaptive statistical iterative reconstruction (ASIR-V) technique. MATERIALS AND MET ... Full text Link to item Cite

Optimizing window settings for improved presentation of virtual monoenergetic images in dual-energy computed tomography.

Journal article Med Phys · November 2017 PURPOSE: Dual-energy computed tomography virtual monoenergetic imaging (VMI) at 40 keV exhibits superior contrast-to-noise ratio (CNR), although practicing radiologists do not consistently prefer it over VMI at 70 keV due to high perceivable noise. We hypo ... Full text Link to item Cite

Effect of Radiation Dose Reduction and Reconstruction Algorithm on Image Noise, Contrast, Resolution, and Detectability of Subtle Hypoattenuating Liver Lesions at Multidetector CT: Filtered Back Projection versus a Commercial Model-based Iterative Reconstruction Algorithm.

Journal article Radiology · September 2017 Purpose To determine the effect of radiation dose and iterative reconstruction (IR) on noise, contrast, resolution, and observer-based detectability of subtle hypoattenuating liver lesions and to estimate the dose reduction potential of the IR algorithm in ... Full text Link to item Cite

Techniques for virtual lung nodule insertion: volumetric and morphometric comparison of projection-based and image-based methods for quantitative CT.

Journal article Phys Med Biol · August 22, 2017 Virtual nodule insertion paves the way towards the development of standardized databases of hybrid CT images with known lesions. The purpose of this study was to assess three methods (an established and two newly developed techniques) for inserting virtual ... Full text Link to item Cite

Dual-Source Single-Energy Multidetector CT Used to Obtain Multiple Radiation Exposure Levels within the Same Patient: Phantom Development and Clinical Validation.

Journal article Radiology · May 2017 Purpose To develop, in a phantom environment, a method to obtain multidetector computed tomographic (CT) data sets at multiple radiation exposure levels within the same patient and to validate its use for potential dose reduction by using different image r ... Full text Link to item Cite

Comparison of low-contrast detectability between two CT reconstruction algorithms using voxel-based 3D printed textured phantoms.

Journal article Med Phys · December 2016 PURPOSE: To use novel voxel-based 3D printed textured phantoms in order to compare low-contrast detectability between two reconstruction algorithms, FBP (filtered-backprojection) and SAFIRE (sinogram affirmed iterative reconstruction) and determine what im ... Full text Link to item Cite

Impact of breast structure on lesion detection in breast tomosynthesis, a simulation study.

Journal article J Med Imaging (Bellingham) · July 2016 This study aims to characterize the effect of background tissue density and heterogeneity on the detection of irregular masses in breast tomosynthesis, while demonstrating the capability of the sophisticated tools that can be used in the design, implementa ... Full text Link to item Cite

Correlation between human detection accuracy and observer model-based image quality metrics in computed tomography.

Journal article J Med Imaging (Bellingham) · July 2016 The purpose of this study was to compare computed tomography (CT) low-contrast detectability from human readers with observer model-based surrogates of image quality. A phantom with a range of low-contrast signals (five contrasts, three sizes) was imaged o ... Full text Link to item Cite

Quantitative Features of Liver Lesions, Lung Nodules, and Renal Stones at Multi-Detector Row CT Examinations: Dependency on Radiation Dose and Reconstruction Algorithm.

Journal article Radiology · April 2016 PURPOSE: To determine if radiation dose and reconstruction algorithm affect the computer-based extraction and analysis of quantitative imaging features in lung nodules, liver lesions, and renal stones at multi-detector row computed tomography (CT). MATERIA ... Full text Link to item Cite

Characteristic image quality of a third generation dual-source MDCT scanner: Noise, resolution, and detectability.

Journal article Med Phys · August 2015 PURPOSE: The purpose of this work was to assess the inherent image quality characteristics of a new multidetector computed tomography system in terms of noise, resolution, and detectability index as a function of image acquisition and reconstruction for a ... Full text Link to item Cite

Diagnostic Performance of an Advanced Modeled Iterative Reconstruction Algorithm for Low-Contrast Detectability with a Third-Generation Dual-Source Multidetector CT Scanner: Potential for Radiation Dose Reduction in a Multireader Study.

Journal article Radiology · June 2015 PURPOSE: To assess the effect of radiation dose reduction on low-contrast detectability by using an advanced modeled iterative reconstruction (ADMIRE; Siemens Healthcare, Forchheim, Germany) algorithm in a contrast-detail phantom with a third-generation du ... Full text Link to item Cite

Evaluating iterative reconstruction performance in computed tomography.

Journal article Med Phys · December 2014 PURPOSE: Iterative reconstruction (IR) offers notable advantages in computed tomography (CT). However, its performance characterization is complicated by its potentially nonlinear behavior, impacting performance in terms of specific tasks. This study aimed ... Full text Link to item Cite

A generic framework to simulate realistic lung, liver and renal pathologies in CT imaging.

Journal article Phys Med Biol · November 7, 2014 Realistic three-dimensional (3D) mathematical models of subtle lesions are essential for many computed tomography (CT) studies focused on performance evaluation and optimization. In this paper, we develop a generic mathematical framework that describes the ... Full text Link to item Cite

Quantum noise properties of CT images with anatomical textured backgrounds across reconstruction algorithms: FBP and SAFIRE.

Journal article Med Phys · September 2014 PURPOSE: Quantum noise properties of CT images are generally assessed using simple geometric phantoms with uniform backgrounds. Such phantoms may be inadequate when assessing nonlinear reconstruction or postprocessing algorithms. The purpose of this study ... Full text Link to item Cite

Design of anthropomorphic Textured phantoms for CT performance evaluation

Journal article Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2014 Commercially available computed Tomography (CT) Technologies such as iterative reconstruction (IR) have The potential To enable reduced patient doses while maintaining diagnostic image quality. However, systematically determining safe dose reduction levels ... Full text Cite

WE-C-103-06: An Automated CT Quality Control Program.

Journal article Med Phys · June 2013 PURPOSE: Daily image quality assessment is an essential part of a rigorous quality control program. Time constraints; however, make it difficult to fully analyze image quality daily. Therefore, the goal of this work was to develop a robust automated CT qua ... Full text Link to item Cite

Relating noise to image quality indicators in CT examinations with tube current modulation.

Journal article AJR Am J Roentgenol · March 2013 OBJECTIVE: Modern CT systems use surrogates of noise-noise index (NI) and quality reference effective tube current-time product (Q)-to infer the quality of images acquired using tube current modulation. This study aimed to determine the relationship betwee ... Full text Link to item Cite

Quantitative comparison of noise texture across CT scanners from different manufacturers.

Journal article Med Phys · October 2012 PURPOSE: To quantitatively compare noise texture across computed tomography (CT) scanners from different manufacturers using the noise power spectrum (NPS). METHODS: The American College of Radiology CT accreditation phantom (Gammex 464, Gammex, Inc., Midd ... Full text Link to item Cite