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Konstantin Arbeev

Associate Research Professor in the Social Science Research Institute
Social Science Research Institute
Box 90420, Durham, NC 27708
2024 W. Main Street, Room A102F, Durham, NC 27705

Scholarly Works - Book sections


Approaches to Statistical Analysis of Longitudinal Data on Aging, Health, and Longevity: Biodemographic Perspectives

Book section · January 1, 2016 Longitudinal data play a pivotal role in discovering different aspects of knowledge related to aging, health, and longevity. There are many statistical methods for the analysis of longitudinal data, which is one of the most prolific areas of statistical sc ... Full text Cite

Continuing the Search for Determinants of Healthy Life Span and Longevity

Book section · January 1, 2016 Life expectancy in humans worldwide has been experiencing dramatic increases for the past two centuries (Oeppen and Vaupel 2002). In most countries, the extension of lifespan is associated with a transition from a long historical period of high fertility a ... Full text Cite

Dynamic Characteristics of Aging-Related Changes as Predictors of Longevity and Healthy Lifespan

Book section · January 1, 2016 It is well known from epidemiological research that values of indices describing physiological states at a given age may influence human morbidity and mortality risks. Studies of the connections between aging and life span suggest that the dynamic properti ... Full text Cite

The Latent Class Stochastic Process Model for Evaluation of Hidden Heterogeneity in Longitudinal Data

Book section · January 1, 2016 Various approaches to statistical model building and data analysis that incorporate unobserved heterogeneity are ubiquitous in different scientific disciplines. Frailty models introduce the concept of unobserved or hidden heterogeneity in survival analysis ... Full text Cite

Stochastic Process Models of Mortality and Aging

Book section · January 1, 2016 A better understanding of relationships among human aging, health, and longevity requires integrative statistical methods capable of taking into account relevant knowledge accumulated in the field when extracting useful information from the data. In this c ... Full text Cite

Evidence for Dependence Among Diseases

Book section · January 1, 2016 Demographic calculations evaluating the role of chronic diseases in life expectancy use the assumption that diseases are independent. Disease independence was a plausible hypothesis in the era of infectious diseases. However, the health problems of modern ... Full text Cite

Age Trajectories of Physiological Indices: Which Factors Influence Them?

Book section · January 1, 2016 Longitudinal data on aging, health, and longevity provide researchers with a unique opportunity to observe aging-related changes in biomarkers that describe the functioning of individual organisms during people’s life courses. In this chapter, empirical es ... Full text Cite

How Biodemographic Approaches Can Improve Statistical Power in Genetic Analyses of Longitudinal Data on Aging, Health, and Longevity

Book section · January 1, 2016 The modern era of revolutionary advances in genetics provides great opportunities and challenges for the field of biodemography. We discuss approaches to work with the rich data available in modern longitudinal studies of aging, health, and longevity that ... Full text Cite

Integrative Mortality Models for the Study of Aging, Health, and Longevity: Benefits of Combining Data

Book section · January 1, 2016 In a number of longitudinal studies, individual health and physiological/biological variables are repeatedly measured for a relatively large number of study subjects. Such data have good potential for evaluating properties of dynamic mechanisms involved in ... Full text Cite

Integrative Mortality Models with Parameters That Have Biological Interpretations

Book section · January 1, 2016 Mortality rates are important characteristics of life span distributions that integrate the influences of many external and internal factors affecting individuals in the population during their life course. These include the ontogenetic program, individual ... Full text Cite

Health Effects and Medicare Trajectories: Population-Based Analysis of Morbidity and Mortality Patterns

Book section · January 1, 2016 The tremendous research potential of U.S. Medicare data for evaluation of current, and forecasting of future, patterns of aging-related diseases among older U.S. adults remains largely unexplored. In this chapter, we present and discuss the results of a se ... Full text Cite

Medical Cost Trajectories and Onset of Age-Associated Diseases

Book section · January 1, 2016 Aging-related deterioration in health impacts an important economic component: the medical costs associated with disease diagnosis and treatment. Because almost all U.S. residents aged 65+ years old are covered by the Medicare system, prediction of future ... Full text Cite

Factors That May Increase Vulnerability to Cancer and Longevity in Modern Human Populations

Book section · January 1, 2016 Cancer incidence rates for all disease sites combined and life expectancy have increased over time in many countries around the world. These increases were concurrent with economic progress and the spread of the Western lifestyle. Overall cancer risk and l ... Full text Cite

Methodological aspects of studying human aging, health, and mortality

Book section · January 1, 2013 Age trajectories of mortality rates in human populations characterize individuals’ inequality in the duration of life. Various models of mortality rates are used in the analyses of survival data in demographic and epidemiological applications aiming to ide ... Full text Cite