Scholars@Duke
Kamrouz Ghadimi

Kamrouz Ghadimi

Adjunct Associate Professor in the Department of Anesthesiology
Anesthesiology, Cardiothoracic
kamrouz.ghadimi@duke.edu
40 Medicine Circle, Box 3094, Durham, NC 27710
2933 Woodstone Lane, Avon, OH 44011

Featured Works

Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery.

Journal article Circulation · October 24, 2023 Featured Publication BACKGROUND: Right ventricular failure (RVF) is a leading driver of morbidity and death after major cardiac surgery for advanced heart failure, including orthotopic heart transplantation and left ventricular assist device implantation. Inhaled pulmonary-sel ... Full text Open Access Link to item Cite

Perioperative Considerations in Management of the Severely Bleeding Coagulopathic Patient.

Journal article Anesthesiology · May 1, 2023 Featured Publication Inherited and acquired coagulopathy are frequently associated with major bleeding in severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage. Perioperative management is multifactorial and includes preoperative optimization an ... Full text Open Access Link to item Cite

Evaluation and Management of Pulmonary Hypertension in Noncardiac Surgery: A Scientific Statement From the American Heart Association.

Journal article Circulation · April 25, 2023 Featured Publication Pulmonary hypertension, defined as an elevation in blood pressure in the pulmonary arteries, is associated with an increased risk of death. The prevalence of pulmonary hypertension is increasing, with an aging population, a rising prevalence of heart and l ... Full text Open Access Link to item Cite

Hydroxocobalamin or Methylene Blue for Vasoplegic Syndrome in Adult Cardiothoracic Surgery.

Journal article J Cardiothorac Vasc Anesth · February 2022 Featured Publication OBJECTIVE: To compare hydroxocobalamin and methylene blue for the treatment of vasopressor-refractory vasoplegic syndrome (VS) after adult cardiac surgery with cardiopulmonary bypass (CPB). DESIGN: A retrospective, propensity-matched, cohort study was perf ... Full text Open Access Link to item Cite

Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial.

Journal article JAMA Surg · January 1, 2022 Featured Publication IMPORTANCE: Inhaled nitric oxide (iNO) is commonly administered for selectively inhaled pulmonary vasodilation and prevention of oxidative injury after lung transplant (LT). Inhaled epoprostenol (iEPO) has been introduced worldwide as a cost-saving alterna ... Full text Open Access Link to item Cite

COVID-19: Thrombosis, thromboinflammation, and anticoagulation considerations.

Journal article Int J Lab Hematol · July 2021 Featured Publication Vascular endothelial injury is a hallmark of acute infection at both the microvascular and macrovascular levels. The hallmark of SARS-CoV-2 infection is the current COVID-19 clinical sequelae of the pathophysiologic responses of hypercoagulability and thro ... Full text Open Access Link to item Cite

Risk of Transmitting Coronavirus Disease 2019 During Nebulizer Treatment: A Systematic Review.

Journal article J Aerosol Med Pulm Drug Deliv · June 2021 Featured Publication Rationale: There is an urgent need to understand the risk of viral transmission during nebulizer treatment of patients with coronavirus disease 2019 (COVID-19). Objectives: To assess the risk of transmitting severe acute respiratory syndrome coronavirus 2 ... Full text Open Access Link to item Cite

Fibrin-modulating nanogels for treatment of disseminated intravascular coagulation.

Journal article Blood Adv · February 9, 2021 Featured Publication Disseminated intravascular coagulation (DIC) is a pathological coagulopathy associated with infection that increases mortality. In DIC, excessive thrombin generation causes symptoms from formation of microthrombi to multiorgan failure; bleeding risks can a ... Full text Open Access Link to item Cite

Three-factor prothrombin complex concentrates for refractory bleeding after cardiovascular surgery within an algorithmic approach to haemostasis.

Journal article Vox Sang · May 2019 Featured Publication BACKGROUND/OBJECTIVES: Prothrombin complex concentrates (PCC) are increasingly administered off-label in the United States to treat bleeding in cardiovascular surgical patients and carry the potential risk for acquired thromboembolic side-effects after sur ... Full text Open Access Link to item Cite

Perioperative management of the bleeding patient.

Journal article Br J Anaesth · December 2016 Featured Publication Perioperative bleeding remains a major complication during and after surgery, resulting in increased morbidity and mortality. The principal causes of non-vascular sources of haemostatic perioperative bleeding are a preexisting undetected bleeding disorder, ... Full text Open Access Link to item Cite

Advancing extubation time for cardiac surgery patients using lean work design.

Journal article J Cardiothorac Vasc Anesth · December 2014 Featured Publication BACKGROUND: Early extubation in select cardiac surgery patients reduces tracheal intubation times, intensive care unit length of stay, and hospital length of stay. While there is good evidence in the literature to support early extubation, there is very li ... Full text Link to item Cite