Journal articleNursing outlook · March 2023
BackgroundOver the last two centuries nurses have been practicing, teaching, and conducting research on social factors that contribute to health and the language has evolved over this time.PurposeTo explore how social factors that contrib ...
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Journal articleThe Journal of the Association of Nurses in AIDS Care : JANAC · January 2023
AbstractStigma is a fundamental cause of health inequities. Guided by the Adaptive Leadership Framework for Chronic Illness (ALFCI), this descriptive qualitative study explored the challenges of stigma and disclosure experienced by women with HIV ...
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Journal articleThe Journal of the Association of Nurses in AIDS Care : JANAC · November 2022
AbstractMen who have sex with men (MSM) and people with HIV (PWH) perceive, internalize, and experience significant stigma from family members, health care providers, and community members because of their sexual behaviors. The current monkeypox ( ...
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Journal articleThe Journal of the Association of Nurses in AIDS Care : JANAC · November 2022
AbstractMonkeypox is a zoonotic infection that manifests as dermatologic lesions that may be painful or pruritic and can appear on the face, trunk, extremities, genitals, and mucosal surfaces. In 2022, cases of monkeypox increased exponentially an ...
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Journal articleBMC women's health · June 2022
BackgroundWomen living with HIV (WLWH) report low engagement in health care, missed office visits, and less engagement in the clinical encounter. Strengthening the clinical encounter for WLWH may improve health outcomes and quality of life. The Ad ...
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Journal articleThe Journal of the Association of Nurses in AIDS Care : JANAC · May 2022
AbstractWomen living with HIV have a higher burden of non-AIDS comorbidities and prevalence of chronic conditions. The Adaptive Leadership Framework for Chronic Illness clarifies living with complex health challenges by delineating the technical w ...
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Journal articleJournal of Interprofessional Education and Practice · March 1, 2022
Preceptors often train students from different educational backgrounds. Many preceptors do not have adequate preparation to assess and educate students from backgrounds that differ from their own. Training students in specialty clinics creates additional c ...
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Journal articleThe Journal of the Association of Nurses in AIDS Care : JANAC · March 2022
AbstractBlack women living with HIV (WLWH) face individual and sociostructural challenges. Despite these challenges, many exemplify remarkable levels of resilience and coping. Yet, research on resilience and coping in this population is limited. T ...
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Journal articleJournal for Nurse Practitioners · January 1, 2022
The development of highly effective antiretroviral treatment has significantly decreased the disease burden and increased the life expectancy of people living with HIV. As people with HIV live longer, they will require ongoing HIV specialty and primary car ...
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Journal articleOpen Forum Infect Dis · August 2021
We report a case of substantial weight gain in a virologically suppressed patient with HIV after changing his antiretroviral therapy from efavirenz/emtricitabine/tenofovir DF to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide with subsequent ra ...
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Journal articleSex Transm Dis · March 1, 2021
BACKGROUND: Few studies have examined long-term outcomes among persons who initiate preexposure prophylaxis (PrEP) in the South, including PrEP discontinuation and sexually transmitted infection (STI) rates. METHODS: Care discontinuation (>6 months without ...
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Journal articleAIDS · November 1, 2020
OBJECTIVES: The aim of this study was to evaluate penetration of antiretrovirals into compartments and efficacy of a dual, NRTI-sparing regimen in acute HIV infection (AHI). DESIGN: Single-arm, open-label pilot study of participants with AHI initiating rit ...
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Journal articleJournal of acquired immune deficiency syndromes (1999) · December 2018
BackgroundWe estimated the effect of initiating virologically suppressive antiretroviral therapy (ART) during acute HIV infection versus chronic HIV infection (AHI vs. CHI) on CD4/CD8 ratio normalization.SettingA prospective clinical coho ...
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Journal articleOpen Forum Infect Dis · November 2018
Transmitted drug resistance to the integrase strand transfer inhibitor (INSTI) class of antiretrovirals is very rare. We present a case of a treatment-naive female patient with human immunodeficiency virus harboring resistance to all INSTIs, including bict ...
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Journal articleAIDS Care · May 2018
Pre-exposure prophylaxis (PrEP) is an effective HIV prevention method, but many primary care physicians (PCPs) have not incorporated PrEP into practice. While PrEP may be a key strategy to reducing high HIV transmission rates in the southern US, knowledge ...
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Journal articleAIDS research and human retroviruses · January 2018
AGS-004 consists of matured autologous dendritic cells co-electroporated with in vitro transcribed RNA encoding autologous HIV antigens. In an open-label, single arm sub-study of AGS-004-003, AGS-004 was administered monthly to suppressed participants who ...
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Journal articleAIDS · November 28, 2016
BACKGROUND: Updated guidelines recommend immediate antiretroviral treatment (ART) during acute HIV infection (AHI), but efficacy data on regimens during AHI are limited. METHODS: We provide final data on a prospective, single-arm 96-week open-label study o ...
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Journal articleThe Journal of the Association of Nurses in AIDS Care : JANAC · May 2016
Responding to a national need for a new workforce of HIV care providers as the first generation of providers decrease their practices or retire, the Duke University School of Nursing, with funding from the Health Resources and Services Administration, deve ...
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Journal articleSexually transmitted diseases · July 2014
BackgroundSexually transmitted infection (STI) diagnosis after diagnosis of acute HIV infection (AHI) indicates ongoing high-risk sexual behavior and possible risk of HIV transmission. We assessed predictors of STI acquisition and the effect of ti ...
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Journal articleJ Acquir Immune Defic Syndr · April 15, 2013
Initiation of antiretroviral therapy during acute HIV-1 infection may prevent persistent immune activation. We analyzed longitudinal CD38+HLA-DR+ CD8+ T-cell percentages in 31 acutely infected individuals who started early (median 43 days since infection) ...
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Journal articleAIDS Res Hum Retroviruses · January 2013
In 1998 a collaboration between Duke University and the University of North Carolina, Chapel Hill (UNC) was founded to enhance identification of persons with acute HIV-1 infection (AHI). The Duke-UNC AHI Research Consortium Cohort consists of patients ≥18 ...
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Journal articleAIDS Res Hum Retroviruses · August 2012
Acute HIV-1 infection causes a rapid total body depletion of CD4(+) T cells in most individuals and HIV-1-specific CD8(+) T cell expansion in response to viral replication. A numerically high CD8 T cell response may indicate limited T cell repertoire again ...
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Journal articleJ Immunol · May 1, 2012
Previous studies have revealed that HIV-infected individuals possess circulating CD4(+)CD8(+) double-positive (DP) T cells specific for HIV Ags. In the present study, we analyzed the proliferation and functional profile of circulating DP T cells from 30 ac ...
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Journal articleDisability and health journal · January 2012
BackgroundIndividuals with disabilities have an elevated risk of residential injury. However, the prevalence of home hazards and safety practices among households where an individual with a disability resides is unknown.MethodsThis study ...
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Journal articleAIDS · April 24, 2011
OBJECTIVE: Characterize responses to non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral treatment (ART) initiated during acute HIV infection (AHI). DESIGN: This was a prospective, single-arm evaluation of once-daily, co-formulated ...
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Journal articlePLoS Pathog · February 10, 2011
In the present study, we analyzed the functional profile of CD8+ T-cell responses directed against autologous transmitted/founder HIV-1 isolates during acute and early infection, and examined whether multifunctionality is required for selection of virus es ...
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Journal articleAntiviral therapy · January 2009
BackgroundTransmitted drug resistance (TDR) limits antiretroviral options and thus complicates the management of HIV-positive patients. HIV disproportionately affects the southern US, but available national estimates of TDR prevalence principally ...
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Journal articleAmerican journal of preventive medicine · January 2005
BackgroundMore needs to be known about the prevalence of risk and protective factors for fires, burns, and carbon monoxide poisoning in U.S. households.MethodsA random-digit-dial survey was conducted about home safety with 1003 respondent ...
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Journal articleInjury control and safety promotion · December 2003
The purpose of this analysis was to quantify the magnitude of death and disability from drowning and near-drowning worldwide and to provide epidemiological data on which to base prevention efforts. All data are from the Global Burden of Disease 2000 (Versi ...
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Journal articleInjury prevention : journal of the International Society for Child and Adolescent Injury Prevention · June 2003
ObjectiveTo systematically review evaluation studies of educational interventions promoting safe firearm storage.MethodsMedline, ERIC, PsycINFO, Criminal Justice Periodicals Index, Cumulative Index of Nursing and Allied Health Literature, ...
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Journal articleArch Pediatr Adolesc Med · August 2002
BACKGROUND: As with other injury prevention practices, education about safe firearm storage is recommended to prevent injuries to children. OBJECTIVE: To assess whether parents who are safety conscious in other respects also practice firearm safety. METHOD ...
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