Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Critical Care Fellowship, Pediatrics/Northwestern University, Ann & Robert H Lurie Children's Hospital of Chicago 2010 - 2013
  • Residency, Pediatrics/Wayne State University, Children's Hospital of Michigan 2007 - 2010
  • D.O., Michigan State University, College of Osteopathic Medicine 2007
• 

  Previous Appointments & Affiliations

  • Instructor in the Department of Pediatrics, Pediatrics, Critical Care Medicine, Pediatrics 2021
• Expertise
• 

  Subject Headings

  • Heart Defects, Congenital
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Cheung, Eva W., Christopher W. Mastropietro, Saul Flores, Venugopal Amula, Monique Radman, David Kwiatkowski, Bao Nguyen Puente, et al. “Procedural Outcomes of Pulmonary Atresia With Intact Ventricular Septum in Neonates: A Multicenter Study.” Ann Thorac Surg 115, no. 6 (June 2023): 1470–77. https://doi.org/10.1016/j.athoracsur.2022.07.055.
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    • Cashen, Katherine, Robert M. Sutton, Ron W. Reeder, Tageldin Ahmed, Michael J. Bell, Robert A. Berg, Candice Burns, et al. “Calcium use during paediatric in-hospital cardiac arrest is associated with worse outcomes.” Resuscitation 185 (April 2023): 109673. https://doi.org/10.1016/j.resuscitation.2022.109673.
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    • Buckley, Jason R., John M. Costello, Arthur J. Smerling, Peter Sassalos, Venu Amula, Katherine Cashen, Christine M. Riley, et al. “Contemporary Multicenter Outcomes for Truncus Arteriosus With Interrupted Aortic Arch.” Ann Thorac Surg 115, no. 1 (January 2023): 144–50. https://doi.org/10.1016/j.athoracsur.2022.08.040.
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    • Chalam, Jennifer N., Jennifer Noble, Amy M. DeLaroche, Robert R. Ehrman, and Katherine Cashen. “Characteristics of Adult Rapid Response Events in a Freestanding Children's Hospital.” Hosp Pediatr 12, no. 12 (December 1, 2022): 1058–65. https://doi.org/10.1542/hpeds.2022-006748.
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    • Kim, Ji-Yeon, Ajit Sarnaik, Ahmad Farooqi, and Katherine Cashen. “Contemporary feeding practices in postoperative patients with Congenital Heart Disease.” Cardiol Young 32, no. 12 (December 2022): 1938–43. https://doi.org/10.1017/S1047951121005229.
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    • Cashen, Katherine, Ron W. Reeder, Tageldin Ahmed, Michael J. Bell, Robert A. Berg, Candice Burns, Joseph A. Carcillo, et al. “Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial.” Pediatr Crit Care Med 23, no. 10 (October 1, 2022): 784–92. https://doi.org/10.1097/PCC.0000000000003045.
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    • Schneider, Jordan, Bradley Tilford, Raya Safa, John Dentel, Michelle Veenstra, Jocelyn Ang, and Katherine Cashen. “Extracorporeal membrane oxygenation for multisystem inflammatory syndrome in children.” Perfusion 37, no. 6 (September 2022): 639–42. https://doi.org/10.1177/02676591211020904.
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    • Tseng, Yu-Shan, Nicole Swaney, Katherine Cashen, Amrish Jain, Nina Ma, and Andrew Prout. “Nephrogenic diabetes insipidus with new onset diabetic ketoacidosis in a child - challenges in fluid and electrolyte management.” Pediatr Nephrol 37, no. 9 (September 2022): 2209–12. https://doi.org/10.1007/s00467-022-05436-1.
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    • Iliopoulos, Ilias, Christopher W. Mastropietro, Saul Flores, Eva Cheung, Venugopal Amula, Monique Radman, David Kwiatkowski, et al. “Pulmonary Atresia with Intact Ventricular Septum: Midterm Outcomes from a Multicenter Cohort.” Pediatr Cardiol, June 25, 2022. https://doi.org/10.1007/s00246-022-02954-5.
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    • Cashen, Katherine, Katherine Regling, and Arun Saini. “Extracorporeal Membrane Oxygenation in Critically Ill Children.” Pediatr Clin North Am 69, no. 3 (June 2022): 425–40. https://doi.org/10.1016/j.pcl.2022.01.008.
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    • Cashen, Katherine, and Raya Safa. “Cardiovascular Critical Care in Children.” Pediatr Clin North Am 69, no. 3 (June 2022): 403–13. https://doi.org/10.1016/j.pcl.2022.02.002.
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    • Lieh-Lai, Mary W., and Katherine Cashen. “[Not Available].” Pediatr Clin North Am 69, no. 3 (June 2022): xv–xvi. https://doi.org/10.1016/j.pcl.2022.03.001.
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    • Martin, Amarilis, Peter T. Rycus, Ahmad Farooqi, John Dentel, and Katherine Cashen. “Extracorporeal membrane oxygenation outcomes in children with Williams syndrome: a review of the ELSO registry.” Perfusion 37, no. 4 (May 2022): 359–66. https://doi.org/10.1177/0267659121999299.
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    • Regling, Katherine, Arun Saini, and Katherine Cashen. “Viscoelastic Testing in Pediatric Mechanical Circulatory Support.” Front Med (Lausanne) 9 (2022): 854258. https://doi.org/10.3389/fmed.2022.854258.
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    • Cashen, Katherine, David M. Kwiatkowski, Christine M. Riley, Jason Buckley, Peter Sassalos, Keshava N. Gowda, Ilias Iliopoulos, et al. “Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery: A Retrospective Multicenter Study.” Pediatr Crit Care Med 22, no. 12 (December 1, 2021): e626–35. https://doi.org/10.1097/PCC.0000000000002820.
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    • Tseng, Yu-Shan, Christopher Herron, Richard Garcia, and Katherine Cashen. “Sustained ventricular tachycardia in a paediatric patient with acute COVID-19 myocarditis.” Cardiol Young 31, no. 9 (September 2021): 1510–12. https://doi.org/10.1017/S1047951121000792.
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    • Grewal, M. K., M. J. Gregory, A. Jain, D. Mohammad, K. Cashen, J. Y. Ang, R. L. Thomas, and R. P. Valentini. “Acute Kidney Injury in Pediatric Acute SARS-CoV-2 Infection and Multisystem Inflammatory Syndrome in Children (MIS-C): Is There a Difference?” Frontiers in Pediatrics 9 (August 9, 2021). https://doi.org/10.3389/fped.2021.692256.
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    • Sanil, Yamuna, Amrit Misra, Raya Safa, Jennifer M. Blake, Ahmad Charaf Eddine, Preetha Balakrishnan, Richard U. Garcia, et al. “Echocardiographic Indicators Associated with Adverse Clinical Course and Cardiac Sequelae in Multisystem Inflammatory Syndrome in Children with Coronavirus Disease 2019.” J Am Soc Echocardiogr 34, no. 8 (August 2021): 862–76. https://doi.org/10.1016/j.echo.2021.04.018.
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    • Abdel-Haq, Nahed, Basim I. Asmar, Maria P. Deza Leon, Eric J. McGrath, Harbir S. Arora, Katherine Cashen, Bradley Tilford, Ahmad Charaf Eddine, Usha Sethuraman, and Jocelyn Y. Ang. “SARS-CoV-2-associated multisystem inflammatory syndrome in children: clinical manifestations and the role of infliximab treatment.” Eur J Pediatr 180, no. 5 (May 2021): 1581–91. https://doi.org/10.1007/s00431-021-03935-1.
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    • Gurkha, Dhritiman, Katie Cashen, Paul Patek, Karima Lelak, and Kelly Levasseur. “Coronavirus-19 Multisystem Inflammatory Syndrome in Children (MIS-C): A Pediatric Simulation Case for Residents, Fellows, and Advanced Practice Providers.” Mededportal 17 (2021): 11180. https://doi.org/10.15766/mep_2374-8265.11180.
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    • Tseng, Y. S., B. Tilford, U. Sethuraman, and K. Cashen. “Combined Hyperglycemic Hyperosmolar Syndrome and Diabetic Ketoacidosis Associated with COVID-19 in a Pediatric Patient.” Case Reports in Critical Care 2021 (January 1, 2021). https://doi.org/10.1155/2021/6429710.
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    • Cashen, Katherine, Tara L. Petersen, Cailyn Rood, Daniel Cater, Sheila F. Waslawski, James E. Slaven, and Christopher W. Mastropietro. “Emergency department utilisation and critical readmission in patients with Fontan circulation.” Cardiol Young 30, no. 12 (December 2020): 1902–9. https://doi.org/10.1017/S1047951120003121.
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    • Bakar, Adnan M., John M. Costello, Peter Sassalos, Venu Amula, Jason R. Buckley, Arthur J. Smerling, Ilias Iliopoulos, et al. “Multicenter Analysis of Truncal Valve Management and Outcomes in Children with Truncus Arteriosus.” Pediatr Cardiol 41, no. 7 (October 2020): 1473–83. https://doi.org/10.1007/s00246-020-02405-z.
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    • Cashen, Katherine, Kathleen Meert, and Heidi J. Dalton. “Platelet Count and Function during Pediatric Extracorporeal Membrane Oxygenation.” Semin Thromb Hemost 46, no. 3 (April 2020): 357–65. https://doi.org/10.1055/s-0040-1708542.
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    • Cashen, K., and A. Martin. “Platelet dysfunction during pediatric cardiac ECMO.” Progress in Pediatric Cardiology 56 (March 1, 2020). https://doi.org/10.1016/j.ppedcard.2019.101187.
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    • Cashen, Katherine, Heidi Dalton, Ron W. Reeder, Arun Saini, Athena F. Zuppa, Thomas P. Shanley, Christopher J. L. Newth, et al. “Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation.” Pediatr Crit Care Med 21, no. 2 (February 2020): 178–85. https://doi.org/10.1097/PCC.0000000000002102.
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    • Riley, Christine M., Christopher W. Mastropietro, Peter Sassalos, Jason R. Buckley, John M. Costello, Ilias Iliopoulos, Aimee Jennings, et al. “Utilization of inhaled nitric oxide after surgical repair of truncus arteriosus: A multicenter analysis.” Congenit Heart Dis 14, no. 6 (November 2019): 1078–86. https://doi.org/10.1111/chd.12849.
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    • Cashen, K., K. Meert, and H. Dalton. “Anticoagulation in Neonatal ECMO: An Enigma Despite a Lot of Effort!.” Frontiers in Pediatrics 7 (September 13, 2019). https://doi.org/10.3389/fped.2019.00366.
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    • Kapur, Gaurav, Lingguang Chen, Yong Xu, Katherine Cashen, Jeff Clark, Xiaoce Feng, and Sean F. Wu. “Noninvasive Determination of Blood Pressure by Heart Sound Analysis Compared With Intra-Arterial Monitoring in Critically Ill Children-A Pilot Study of a Novel Approach.” Pediatr Crit Care Med 20, no. 9 (September 2019): 809–16. https://doi.org/10.1097/PCC.0000000000001997.
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    • Cashen, Katherine, and Tara Petersen. “Diabetic Ketoacidosis.” Pediatr Rev 40, no. 8 (August 2019): 412–20. https://doi.org/10.1542/pir.2018-0231.
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    • Czolgosz, Thomas, Katherine Cashen, Ahmad Farooqi, and Nirupama Kannikeswaran. “Delayed Admissions to the Pediatric Intensive Care Unit: Progression of Disease or Errors in Emergency Department Management.” Pediatr Emerg Care 35, no. 8 (August 2019): 568–74. https://doi.org/10.1097/PEC.0000000000001887.
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    • Gradidge, Eleanor A., Lisa M. Grimaldi, Katherine Cashen, Keshava M. N. Gowda, Kurt D. Piggott, Michael Wilhelm, John M. Costello, and Christopher W. Mastropietro. “Near-infrared spectroscopy for prediction of extubation success after neonatal cardiac surgery.” Cardiol Young 29, no. 6 (June 2019): 787–92. https://doi.org/10.1017/S1047951119000829.
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    • Mastropietro, Christopher W., Venu Amula, Peter Sassalos, Jason R. Buckley, Arthur J. Smerling, Ilias Iliopoulos, Christine M. Riley, et al. “Characteristics and operative outcomes for children undergoing repair of truncus arteriosus: A contemporary multicenter analysis.” J Thorac Cardiovasc Surg 157, no. 6 (June 2019): 2386-2398.e4. https://doi.org/10.1016/j.jtcvs.2018.12.115.
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    • Buckley, Jason R., Venu Amula, Peter Sassalos, John M. Costello, Arthur J. Smerling, Ilias Iliopoulos, Aimee Jennings, et al. “Multicenter Analysis of Early Childhood Outcomes After Repair of Truncus Arteriosus.” Ann Thorac Surg 107, no. 2 (February 2019): 553–59. https://doi.org/10.1016/j.athoracsur.2018.08.094.
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    • Cashen, Katherine, John M. Costello, Lisa M. Grimaldi, Keshava Murty Narayana Gowda, Elizabeth A. S. Moser, Kurt D. Piggott, Michael Wilhelm, and Christopher W. Mastropietro. “Multicenter Validation of the Vasoactive-Ventilation-Renal Score as a Predictor of Prolonged Mechanical Ventilation After Neonatal Cardiac Surgery.” Pediatr Crit Care Med 19, no. 11 (November 2018): 1015–23. https://doi.org/10.1097/PCC.0000000000001694.
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    • Dalton, Heidi J., Katherine Cashen, Ron W. Reeder, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, et al. “Hemolysis During Pediatric Extracorporeal Membrane Oxygenation: Associations With Circuitry, Complications, and Mortality.” Pediatr Crit Care Med 19, no. 11 (November 2018): 1067–76. https://doi.org/10.1097/PCC.0000000000001709.
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    • Cashen, Katherine, Ron Reeder, Heidi J. Dalton, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, et al. “Acquired infection during neonatal and pediatric extracorporeal membrane oxygenation.” Perfusion 33, no. 6 (September 2018): 472–82. https://doi.org/10.1177/0267659118766436.
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    • Cashen, Katherine, Ron W. Reeder, Christina Shanti, Heidi J. Dalton, J Michael Dean, Kathleen L. Meert, and Kathleen L. Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN). “Is therapeutic hypothermia during neonatal extracorporeal membrane oxygenation associated with intracranial hemorrhage?” Perfusion 33, no. 5 (July 2018): 354–62. https://doi.org/10.1177/0267659117747693.
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    • Cashen, Katherine, and Ashok P. Sarnaik. “Ventilator-Associated Conditions: Are the New Definitions "Eliminating the Noise" or Ignoring Important Preconditions?” Pediatr Crit Care Med 19, no. 6 (June 2018): 578–79. https://doi.org/10.1097/PCC.0000000000001541.
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    • Cashen, Katherine, Ron Reeder, Heidi J. Dalton, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, et al. “Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors.” Pediatr Crit Care Med 19, no. 3 (March 2018): 245–53. https://doi.org/10.1097/PCC.0000000000001439.
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    • Cashen, Katherine, Ron Reeder, Heidi J. Dalton, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, et al. “Functional Status of Neonatal and Pediatric Patients After Extracorporeal Membrane Oxygenation.” Pediatr Crit Care Med 18, no. 6 (June 2017): 561–70. https://doi.org/10.1097/PCC.0000000000001155.
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    • Cashen, Katherine, and Tara L. Petersen. “Pleural Effusions and Pneumothoraces.” Pediatr Rev 38, no. 4 (April 2017): 170–81. https://doi.org/10.1542/pir.2016-0088.
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    • Cashen, Katherine, Roland L. Chu, Justin Klein, Peter T. Rycus, and John M. Costello. “Extracorporeal membrane oxygenation outcomes in children with hemophagocytic lymphohistiocytosis.” Perfusion 32, no. 2 (March 2017): 151–56. https://doi.org/10.1177/0267659116667804.
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    • Mastropietro, Christopher W., Katherine Cashen, Lisa M. Grimaldi, Keshava Murty Narayana Gowda, Kurt D. Piggott, Michael Wilhelm, Eleanor Gradidge, Elizabeth A. S. Moser, Brian D. Benneyworth, and John M. Costello. “Extubation Failure after Neonatal Cardiac Surgery: A Multicenter Analysis.” J Pediatr 182 (March 2017): 190-196.e4. https://doi.org/10.1016/j.jpeds.2016.12.028.
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    • Cashen, K., T. K. Hollis, R. E. Delius, and K. L. Meert. “Extracorporeal membrane oxygenation for pediatric cardiac failure: Review with a focus on unique subgroups.” Progress in Pediatric Cardiology 43 (December 1, 2016): 105–11. https://doi.org/10.1016/j.ppedcard.2016.05.003.
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    • Cashen, Katherine, and Tara Petersen. “Pediatric Pulseless Ventricular Tachycardia: A Simulation Scenario for Fellows, Residents, Medical Students, and Advanced Practitioners.” Mededportal 12 (June 3, 2016): 10407. https://doi.org/10.15766/mep_2374-8265.10407.
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    • Cashen, Katherine, Bradley Tilford, Ajit Sarnaik, and Jeff Clark. “Pediatric Complete Heart Block.” Mededportal, February 12, 2016. https://doi.org/10.15766/mep_2374-8265.10348.
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    • Hollis, Taemyn, Bradley Tilford, and Katherine Cashen. “An Infant With Single Ventricle Physiology and Hypoxemia.” Mededportal, December 29, 2015. https://doi.org/10.15766/mep_2374-8265.10323.
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    • Hollis, Taemyn, Katherine Cashen, and Peter Rycus. “1156.” Critical Care Medicine 43 (December 2015): 290–91. https://doi.org/10.1097/01.ccm.0000474987.45769.e2.
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    • Hollis, Taemyn, Katherine Cashen, and Peter Rycus. “1129.” Critical Care Medicine 43 (December 2015): 284–284. https://doi.org/10.1097/01.ccm.0000474960.49340.fc.
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    • Levasseur, Kelly, and Katherine Cashen. “Infant With Adrenal Insufficiency and Shock.” Mededportal, August 28, 2015. https://doi.org/10.15766/mep_2374-8265.10173.
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    • Cashen, Katherine, Ravi R. Thiagarajan, James W. Collins, Peter T. Rycus, Carl L. Backer, Marleta Reynolds, and John M. Costello. “Extracorporeal Membrane Oxygenation in Pediatric Trisomy 21: 30 Years of Experience from the Extracorporeal Life Support Organization Registry.” J Pediatr 167, no. 2 (August 2015): 403–8. https://doi.org/10.1016/j.jpeds.2015.04.048.
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    • Cashen, Katherine, Roland Chu, Justin Klein, Peter Rycus, and John Costello. “1041.” Critical Care Medicine 42 (December 2014): A1610–11. https://doi.org/10.1097/01.ccm.0000458538.32999.57.
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    • Cashen, Katherine, Nguyenvu Nguyen, Hantamalala Ralay-Ranaivo, Shannon Haymond, RayeAnn deReigner, Donald Chace, Victor DeJesus, and Mark Wainwright. “266.” Critical Care Medicine 41 (December 2013): A61–A61. https://doi.org/10.1097/01.ccm.0000439412.13139.99.
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    • Cashen, Katherine, Pooja Gupta, Mary Lieh-Lai, and Christopher Mastropietro. “Infants with single ventricle physiology in the emergency department: are physicians prepared?” J Pediatr 159, no. 2 (August 2011): 273-7.e1. https://doi.org/10.1016/j.jpeds.2011.01.031.
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    • Cashen, Katherine, and Deepak Kamat. “Recurrent fever and rash.” Clin Pediatr (Phila) 48, no. 6 (July 2009): 679–82. https://doi.org/10.1177/0009922809333090.
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    • Mohawk, Jennifer A., Katherine Cashen, and Theresa M. Lee. “Inhibiting cortisol response accelerates recovery from a photic phase shift.” Am J Physiol Regul Integr Comp Physiol 288, no. 1 (January 2005): R221–28. https://doi.org/10.1152/ajpregu.00272.2004.
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    • Kwiatkowski, David M., Christopher W. Mastropietro, Katherine Cashen, Saurabh Chiwane, Saul Flores, Ilias Iliopoulos, Karan B. Karki, et al. “Characteristics and Surgical Outcomes of Patients With Late Presentation of Anomalous Left Coronary Artery From the Pulmonary Artery: A Multicenter Study.” Semin Thorac Cardiovasc Surg 33, no. 1 (n.d.): 141–50. https://doi.org/10.1053/j.semtcvs.2020.08.014.
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  • Book Sections

    • Cashen, K., S. Sehgal, and H. L. Walters. “Pediatric mechanical circulatory support.” In Cardiac Emergencies in Children: A Practical Approach to Diagnosis and Management, 201–18, 2018. https://doi.org/10.1007/978-3-319-73754-6_12.
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    • Sarnaik, S., K. Cashen, and A. P. Sarnaik. “Emergency presentation of heart disease.” In Cardiac Emergencies in Children: A Practical Approach to Diagnosis and Management, 1–15, 2018. https://doi.org/10.1007/978-3-319-73754-6_1.
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  • Conference Papers

    • Cashen, Katherine, Kathleen Meert, Ron Reeder, Robert Berg, Kellimarie Cooper, John Wesley Diddle, Kathryn Graham, et al. “CAUTION FOR CALCIUM USE DURING PEDIATRIC CPR: DO SELECTED RESUSCITATION SCENARIOS BENEFIT?” In Critical Care Medicine, 50:693–693, 2022.
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    • Khan, Mohammad, Chris Smith, John Dentel, Ahmad Farooqi, and Katherine Cashen. “EARLY EXTUBATION GUIDELINE DECREASES LENGTH OF MECHANICAL VENTILATION IN PEDIATRIC CARDIAC SURGERY.” In Critical Care Medicine, 50:642–642, 2022.
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    • Radman, Monique, Christopher W. Mastropietro, John M. Costello, Venu Amula, Saul Flores, Elizabeth Caudill, Karan Karki, et al. “Intermediate Outcomes After Repair of Anomalous Left Coronary Artery From the Pulmonary Artery.” In Ann Thorac Surg, 112:1307–15, 2021. https://doi.org/10.1016/j.athoracsur.2020.06.130.
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