Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellowship, Pediatric Anesthesiology, Duke University School of Medicine 2012 - 2013
  • Residency, Anesthesiology, Drexel University, College of Medicine 2008 - 2011
  • M.D., University of North Carolina - Chapel Hill 2006
• 

  Duke Appointment History

  • Associate Professor of Anesthesiology, Anesthesiology, Pediatrics, Anesthesiology 2019 - 2020
  • Assistant Professor of Anesthesiology, Anesthesiology, Pediatrics, Anesthesiology 2013 - 2019
• Research
• 

  Selected Grants

  • Grunenthal KF550372 awarded by Grunenthal GmbH 2016 - 2017
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Andrews, Jon S., and Kelly A. Machovec. “Home is Where the Heart Is: Interstage Home Monitoring in Infants With Single-Ventricle Heart Disease.” J Cardiothorac Vasc Anesth 35, no. 10 (October 2021): 2835–37. https://doi.org/10.1053/j.jvca.2021.05.033.
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    • Machovec, Kelly A., and Warwick A. Ames. “Evidence-Based Medicine in the Time of COVID: We Have a Problem.” J Cardiothorac Vasc Anesth 35, no. 5 (May 2021): 1274–75. https://doi.org/10.1053/j.jvca.2020.10.058.
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    • Ames, Warwick Aubrey, and Kelly Machovec. “An update on the management of PONV in a pediatric patient.” Best Pract Res Clin Anaesthesiol 34, no. 4 (December 2020): 749–58. https://doi.org/10.1016/j.bpa.2020.05.007.
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    • Finucane, Elizabeth, Edmund Jooste, and Kelly A. Machovec. “Neuromonitoring Modalities in Pediatric Cardiac Anesthesia: A Review of the Literature.” J Cardiothorac Vasc Anesth 34, no. 12 (December 2020): 3420–28. https://doi.org/10.1053/j.jvca.2020.02.054.
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    • Machovec, Kelly A., and Warwick A. Ames. “Recycle: Do It for the Kids.” J Cardiothorac Vasc Anesth 34, no. 12 (December 2020): 3352–53. https://doi.org/10.1053/j.jvca.2020.07.030.
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    • Machovec, Kelly A., and Warwick A. Ames. “Big Syringe, Little Syringe.” J Cardiothorac Vasc Anesth 34, no. 9 (September 2020): 2401–2. https://doi.org/10.1053/j.jvca.2020.05.017.
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    • Barnett, Annika M., Kelly A. Machovec, Warwick A. Ames, Hercilia M. Homi, Jennifer L. Turi, Jeannie Koo, Matthew Fuller, and Edmund H. Jooste. “The effect of intraoperative methadone during pediatric cardiac surgery on postoperative opioid requirements.” Paediatr Anaesth 30, no. 7 (July 2020): 773–79. https://doi.org/10.1111/pan.13903.
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    • Machovec, Kelly A., and Edmund H. Jooste. “The Database Dilemma: An Imperfect but Critical Tool to Improve Quality and Benchmark Outcomes.” J Cardiothorac Vasc Anesth 33, no. 10 (October 2019): 2615–17. https://doi.org/10.1053/j.jvca.2019.03.065.
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    • Machovec, Kelly A., and Edmund H. Jooste. “Pediatric Transfusion Algorithms: Coming to a Cardiac Operating Room Near You.” J Cardiothorac Vasc Anesth 33, no. 7 (July 2019): 2017–29. https://doi.org/10.1053/j.jvca.2018.12.008.
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    • Machovec, Kelly A., and Warwick A. Ames. “Primum Non Nocere.” J Cardiothorac Vasc Anesth 33, no. 7 (July 2019): 1930–31. https://doi.org/10.1053/j.jvca.2019.01.038.
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    • Jones, Stephanie E., Edmund H. Jooste, Erin A. Gottlieb, Jamie Schwartz, Dheeraj Goswami, Nischal K. Gautam, Claudia Benkwitz, et al. “Preoperative Laboratory Studies for Pediatric Cardiac Surgery Patients: A Multi-Institutional Perspective.” Anesth Analg 128, no. 5 (May 2019): 1051–54. https://doi.org/10.1213/ANE.0000000000004114.
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    • P Mathew, Jonathan, and Kelly A. Machovec. “A New Paradigm of Anxiolysis.” J Cardiothorac Vasc Anesth 33, no. 5 (May 2019): 1251–52. https://doi.org/10.1053/j.jvca.2018.09.022.
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    • Jooste, Edmund H., Rebecca Scholl, Yi-Hung Wu, Robert D. B. Jaquiss, Andrew J. Lodge, Warwick A. Ames, H Mayumi Homi, et al. “Double-Blind, Randomized, Placebo-Controlled Trial Comparing the Effects of Antithrombin Versus Placebo on the Coagulation System in Infants with Low Antithrombin Undergoing Congenital Cardiac Surgery.” J Cardiothorac Vasc Anesth 33, no. 2 (February 2019): 396–402. https://doi.org/10.1053/j.jvca.2018.05.052.
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    • Jooste, Edmund H., and Kelly A. Machovec. “Hypercoagulability - The Underdiagnosed and Undertreated Nemesis of Congenital Heart Surgery.” J Cardiothorac Vasc Anesth 32, no. 4 (August 2018): 1664–66. https://doi.org/10.1053/j.jvca.2018.01.016.
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    • Einhorn, Lisa M., Brad M. Taicher, Nathaniel H. Greene, Leon J. Reinstein, Edmund H. Jooste, Michael J. Campbell, and Kelly A. Machovec. “Percutaneous endoscopic gastrostomy vs surgical gastrostomy in infants with congenital heart disease.” Paediatr Anaesth 28, no. 7 (July 2018): 612–17. https://doi.org/10.1111/pan.13416.
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    • Jooste, Edmund H., and Kelly A. Machovec. “It is Time to Stop Missing the Forest for the Trees: The Debate on Corticosteroid Use in Pediatric Heart Surgery.” J Cardiothorac Vasc Anesth 31, no. 6 (December 2017): 1957–59. https://doi.org/10.1053/j.jvca.2017.06.035.
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    • Machovec, Kelly A., Nathaniel H. Greene, Eileen M. Raynor, and Brad M. Taicher. “Bilateral Upper Lobe Bronchi Originating from the Trachea.” Anesthesiology 127, no. 6 (December 2017): 1015. https://doi.org/10.1097/ALN.0000000000001805.
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    • Machovec, Kelly A., and Deepu S. Ushakumari. “Time Is Money.” Anesth Analg 125, no. 2 (August 2017): 372–74. https://doi.org/10.1213/ANE.0000000000002204.
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    • Machovec, Kelly A., Brad Taicher, Robert D. B. Jaquiss, and Kevin D. Hill. “Images in Anesthesiology: Anomalous Single Coronary Artery from the Pulmonary Artery.” Anesthesiology 126, no. 6 (June 2017): 1169. https://doi.org/10.1097/ALN.0000000000001532.
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    • Tew, Shannon, Manuel L. Fontes, Nathaniel H. Greene, Miklos D. Kertai, George Ofori-Amanfo, Robert D. B. Jaquiss, Andrew J. Lodge, et al. “Natural history of nonimmune-mediated thrombocytopenia and acute kidney injury in pediatric open-heart surgery.” Paediatric Anaesthesia 27, no. 3 (March 2017): 305–13. https://doi.org/10.1111/pan.13063.
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    • Jooste, Edmund H., Kelly A. Machovec, Lisa M. Einhorn, Warwick A. Ames, Hercilia M. Homi, Robert D. B. Jaquiss, Andrew J. Lodge, Jerrold H. Levy, and Ian J. Welsby. “3-Factor Prothrombin Complex Concentrates in Infants With Refractory Bleeding After Cardiac Surgery.” J Cardiothorac Vasc Anesth 30, no. 6 (December 2016): 1627–31. https://doi.org/10.1053/j.jvca.2016.01.029.
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    • Amhaz, Hassan H., Kate Buretta, Edmund H. Jooste, Kelly Machovec, Jeffery R. Marcus, and Warwick A. Ames. “Upper Extremity Peripheral Intravenous Line Infiltration With Concomitant Loss of Pulses Treated With Lipoaspiration: A Case Report.” A a Case Rep 7, no. 9 (November 1, 2016): 185–87. https://doi.org/10.1213/XAA.0000000000000381.
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    • Gregory, Stephen H., Madhav Swaminathan, Yasmin Maisonave, and Kelly A. Machovec. “Management of 1-Lung Ventilation in a Patient With Failing Fontan Circulation.” A a Case Rep 7, no. 8 (October 15, 2016): 177–80. https://doi.org/10.1213/XAA.0000000000000377.
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    • Machovec, Kelly A., Gregory Smigla, Warwick A. Ames, Courtney Schwimer, H Mayumi Homi, Ishwori B. Dhakal, Robert D. B. Jaquiss, Andrew J. Lodge, and Edmund H. Jooste. “Reduction in blood transfusion in a cohort of infants having cardiac surgery with cardiopulmonary bypass after instituting a goal-directed transfusion policy.” Perfusion 31, no. 7 (October 2016): 598–603. https://doi.org/10.1177/0267659116640866.
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    • Eapen, Rose J., Brad M. Taicher, Eric Benner, and Kelly Machovec. “Laryngeal Cleft.” Anesthesiology, August 30, 2016. https://doi.org/10.1097/ALN.0000000000001337.
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    • Machovec, Kelly A., Robert D. B. Jaquiss, David D. Kaemmer, Warwick A. Ames, Hercilia M. Homi, Richard J. Walczak, Andrew J. Lodge, and Edmund H. Jooste. “Cardiopulmonary Bypass Strategy for a Cyanotic Child With Hemoglobin SC Disease.” Ann Thorac Surg 101, no. 6 (June 2016): 2373–75. https://doi.org/10.1016/j.athoracsur.2015.09.046.
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    • McCartney, Sharon L., Kelly Machovec, and Edmund H. Jooste. “Uncorrected Tetralogy of Fallot, Biventricular Dysfunction, and a Large Pericardial Effusion.” J Cardiothorac Vasc Anesth 29, no. 5 (October 2015): 1391–95. https://doi.org/10.1053/j.jvca.2015.06.033.
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    • Machovec, Kelly A., Edmund H. Jooste, Richard J. Walczak, Hercilia Mayumi Homi, Robert D. B. Jaquiss, Andrew J. Lodge, and Warwick A. Ames. “A change in anticoagulation monitoring improves safety, reduces transfusion, and reduces costs in infants on cardiopulmonary bypass.” Paediatr Anaesth 25, no. 6 (June 2015): 580–86. https://doi.org/10.1111/pan.12591.
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    • Nimjee, Shahid M., Tony P. Smith, Ronald J. Kanter, Warwick Ames, Kelly A. Machovec, Gerald A. Grant, and Ali R. Zomorodi. “Rapid ventricular pacing for a basilar artery pseudoaneurysm in a pediatric patient: case report.” J Neurosurg Pediatr 15, no. 6 (June 2015): 625–29. https://doi.org/10.3171/2014.11.PEDS14290.
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    • Machovec, Kelly A., Deepu S. Ushakumari, Ian J. Welsby, and Vance G. Nielsen. “The procoagulant properties of purified fibrinogen concentrate are enhanced by carbon monoxide releasing molecule-2.” Thromb Res 129, no. 6 (June 2012): 793–96. https://doi.org/10.1016/j.thromres.2011.08.005.
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    • Brodsky, Melissa A., Kelly A. Machovec, Bryan P. Chambers, and Vance G. Nielsen. “Platelet-mediated thrombolysis in patients with δ-storage pool deficiency: a thrombelastographic analysis.” Blood Coagul Fibrinolysis 22, no. 7 (October 2011): 610–12. https://doi.org/10.1097/MBC.0b013e328349a2a4.
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    • Malayaman, Saninuj N., Jack B. Cohen, Kelly A. Machovec, Brian E. Bernhardt, Matt R. Arkebauer, and Vance G. Nielsen. “Carbon monoxide releasing molecule-2 enhances α2-antiplasmin activity.” Blood Coagul Fibrinolysis 22, no. 4 (June 2011): 345–48. https://doi.org/10.1097/MBC.0b013e328344c657.
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  • Book Sections

    • MacHovec, K. A., and B. Craig Weldon. “Pediatric transfusion therapy and blood conservation.” In Essentials of Pediatric Anesthesiology, 305–14, 2014. https://doi.org/10.1007/9781107375338.
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